المؤلفون: Maria Alice V. Willrich, Paula M. Ladwig

المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 10-18 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab

مصطلحات موضوعية: RAVUL, ravulizumab, Clinical Biochemistry, MW, molecular weight, LDT, lab-developed test, law.invention, Complement inhibitor, AMR, analytical measuring range, law, NIVOL, nivolumab, Intact light chain, IS, internal standard, Spectroscopy, LC, liquid chromatography, Chemistry, Ravulizumab, Eculizumab, Isotype, Orbitrap, Therapeutic monitoring, Medical Laboratory Technology, HPLC, high performance liquid chromatography, Research Article, LLOQ, lower limit of quantitation, IRB, Institutional Review Board, ECUL, eculizumab, Mass spectrometry, Microbiology, Fc, crystallizable fragment, t-mAb, therapeutic monoclonal antibody, LLOD, lower limit of detection, PNH, paroxysmal nocturnal hemoglobinuria, Time of flight, PBS, phosphate buffered saline, Affinity chromatography, LOB, limit of blankMS, mass spectrometry, C5, complement component 5, Medical technology, R855-855.5, aHUS, atypical hemolytic uremic syndrome, Chromatography, Orbitrap ms, Intact protein, Q-TOF, quadrupole time-of-flight, XIC, extracted ion chromatogram, DTT, dithiothreitol, Therapeutic monoclonal antibody, Da, daltons, NHS, normal human serum

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88685fcc88f512f223cf9cedd64e9176
http://www.sciencedirect.com/science/article/pii/S2667145X21000146

المؤلفون: Bojana Rakic, Hilary Vallance, Joshua A. Dubland, Graham Sinclair

المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 1-10 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab

مصطلحات موضوعية: Newborn screening, MS/MS, tandem mass spectrometry, 2-Methylcitric acid, Homocysteine, Clinical Biochemistry, rpm, revolutions per minute, Methylmalonic acid, Tandem mass spectrometry, MMA, methylmalonic acid, NBS, newborn screening, chemistry.chemical_compound, DMAP, 4-(dimethylamino)pyridine, Met, methionine, Liquid chromatography–mass spectrometry, HCl, hydrochloric acid, health care economics and organizations, DBS, dried blood spot, Spectroscopy, FA, formic acid, ESI, electrospray ionization, Second-tier, LC, liquid chromatography, food and beverages, Regular Article, Dried blood spot, Medical Laboratory Technology, Specimen collection, S/N, signal-to-noise, GC, gas chromatography, Phe, phenylalanine, DAABD-AE, 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole, LLOQ, lower limit of quantitation, Analyte, HCY, homocysteine, education, MCA, 2-methylcitric acid, Cbl, cobalamin, Microbiology, LLOD, lower limit of detection, GPCho’s, glycerophosphocholines, health services administration, EDC, N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, Medical technology, C2, acetylcarnitine, R855-855.5, Derivatization, CBS, cystathionine β-synthase, MPs, mobile phases, Chromatography, Mass spectrometry, C3, propionylcarnitine, PPV, positive predictive value, QC, quality control, MS, mass spectrometry, chemistry, DTT, dithiothreitol, MRM, multiple reaction monitoring

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50beebd48c7a916d499a13356b9284c0
https://doi.org/10.1016/j.jmsacl.2021.03.001

المؤلفون: Siripat, Khammesri, Chadarat, Ampasavate, Darunee, Hongwiset, Raktham, Mektrirat, Siriluk, Sangsrijan, Janine L, Brown, Chatchote, Thitaram

المصدر: Veterinary and Animal Science

مصطلحات موضوعية: EEHV-HD, Elephant endotheliotropic herpesvirus hemorrhagic disease, Bioavailability, LLOQ, Lower limit of quantitation, %CV, Mean precision, Acyclovir, m/z, Mass-to-charge ratio, Article, MRT, Mean residence time, T1/2, Elimination half-life, Cmax, Peak plasma concentration, AUC0-inf, Total area under the plasma concentration-time curve from time zero to infinity, Pharmacokinetics, HSV, Herpes simplex virus, Kel, Elimination rate constant, QC, Quality control, Vd(ss), Steady-state volume of distribution, EHV, Equid alphaherpesvirus, F, Bioavailability, virus diseases, IV, Intravenous administration, r2, Coefficients of determination, Cl, Total clearance, S/N, Signal to noise ratio, EEHV, Elephantendotheliotropic herpesviruses, PO, Oral administration, Tmax, Time to reach peak plasma, MAT, Mean absorption time, Elephant endotheliotropic herpesvirus (EEHV), LC-MS/MS, Liquid chromatography-tandem mass spectrometry, AUC0-t, Total area under the plasma concentration-time curve from time 0–48h, Asian elephant, MRM, Multiple reaction monitoring

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::2588efe2c1ce851fda186c5e0639132e
https://pubmed.ncbi.nlm.nih.gov/35024493

المؤلفون: Cora Wunder, Werner Pogoda, Alexander Paulke, Stefan W. Toennes

المصدر: MethodsX
MethodsX, Vol 8, Iss, Pp 101563-(2021)

مصطلحات موضوعية: LLOQ, lower limit of quantitation, LOD, limit of detection, Method validation, Science, Post-offence drinking, Methanol, HS, headspace, Cal, calibrator, GTFCh, Gesellschaft für Toxikologische und Forensische Chemie, Method Article, CV, coefficients of variation, 1-propanol, QC, quality control, MS, mass spectrometry, ISTD, internal standard, EI, electron impact ionization, FID, flame ionization detection, Alcohol, GC, gas chromatography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c3c0474cca9fa44b8f45acd0f068e1d8
https://pubmed.ncbi.nlm.nih.gov/34754825

المؤلفون: Wenjuan Hu, Bo Tan, Lu Chang, Yuanchao Xie, Jia Liu, Chang-Qiang Ke, Jingshan Shen

المصدر: Journal of Pharmaceutical and Biomedical Analysis

مصطلحات موضوعية: Male, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, PPT, protein precipitation, Analytical Chemistry, chemistry.chemical_compound, Mice, FDA, United States Federal Drug Administration, Tandem Mass Spectrometry, Recovery, Drug Discovery, Nucleotide, Prodrugs, ATNs, active triphosphate nucleotide metabolites, IS, internal standard, RDV, remdesivir, Spectroscopy, FA, formic acid, chemistry.chemical_classification, Aqueous solution, Alanine, ESI, electrospray ionization, Prodrug, LLE, liquid-liquid extraction, Liver, COVID 19, coronavirus disease 2019, RSDs, relative standard deviations, RMP, remdesivir monophosphate, Stability, NH4Ac, ammonium acetate, LLOQ, lower limit of quantitation, Bioanalysis, ATP, adenosine triphosphate, Formic acid, UPLC-MS/MS, ultra-performance liquid chromatography coupled triple-quadrupole mass spectrometry, Electrospray ionization, KD, equilibrium dissociation constant, Remdesivir, Mass spectrometry, Antiviral Agents, Nucleotide triphosphate, Article, LC–MS/MS, FT-ICR MS, fourier transform ion cyclotron resonance mass spectrometry, RTP, remdesivir nucleotide triphosphate, Animals, Humans, AgNO3, silver nitrate, RdRp, RNA-dependent RNA polymerases, TCEP, tris (2 carboxyethyl) phosphine hydrochloride, Active metabolite, ComputingMethodologies_COMPUTERGRAPHICS, Chromatography, 010405 organic chemistry, Nucleotide monophosphate, 010401 analytical chemistry, SPE, solid-phase extraction, COVID-19, DTNB, 55′ dithiobis (2-nitrobenzoic acid), ACN, acetonitrile, Adenosine Monophosphate, 0104 chemical sciences, COVID-19 Drug Treatment, BNPP, bis (p-nitrophenyl) phosphate, QC, quality control, RN, remdesivir nucleoside, chemistry, SARS CoV 2, severe acute respiratory coronavirus 2, MeOH, methanol, UTP, uridine triphosphate, HSA, human serum albumin, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34f48353e81866b14c556b4dd902bf8
http://europepmc.org/articles/PMC7703390

المؤلفون: I.G. Bressán, Susana Francisca Llesuy, María Isabel Giménez

المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 19, Iss, Pp 7-19 (2021)

مصطلحات موضوعية: ESI+, Positive electrospray source ionization mode, LC-MS/MS, Liquid chromatography coupled to tandem mass spectrometry, C0, Pre-dose trough concentration, Clinical Biochemistry, LLOQ, Lower limit of quantitation, PCDBS, Pre-cut dried blood spots, Context (language use), QC, Quality control samples, CV%, Coefficient of variation, Tandem mass spectrometry, Microbiology, DBS, Dried blood spots, Matrix (chemical analysis), Method comparison, R%, Relative recovery, CS, Calibration standard, Cyclosporin a, medicine, Medical technology, [M+NH4]+, Ammoniated adduct, ICb95%, 95% confidence interval for intercepts, R855-855.5, mTOR, Mechanistic target of Rapamycin, ZnSO4·7H2O, Zinc sulfate heptahydrate, Spectroscopy, Ht, Hematocrit, DMPS, Dried matrix on paper discs, ComputingMethodologies_COMPUTERGRAPHICS, Everolimus, Chromatography, medicine.diagnostic_test, Chemistry, LSS, Limited sampling strategy, Dried matrix on paper discs (DMPD), PIs, Prediction intervals, Gold standard (test), ICm95%, 95% confidence interval for slopes, Immunosuppressants, Medical Laboratory Technology, PDBS, Perforated dried blood spots, Hematocrit, C2, 2-hour post-dose concentration, RE%, Percentage of the relative error, Therapeutic drug monitoring, Sample collection, Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1b1bf3289038564893ac12f0145981
https://pubmed.ncbi.nlm.nih.gov/34820661

المؤلفون: Junke Song, Li Zhang, Yanfeng Xu, Dezhi Yang, Shiying Yang, Wen Zhang, Jinhua Wang, Shuo Tian, Shengqian Yang, Tianyi Yuan, Ailin Liu, Qi Lv, Fengdi Li, Hongqi Liu, Biyu Hou, Xiaozhong Peng, Yang Lu, Guanhua Du

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Male, EEP, end-expiratory pause, DENV, dengue virus, SI, selection index, Pharmacology, ZIKV, Zika virus, Biochemistry, Antioxidants, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Random Allocation, 0302 clinical medicine, Oral administration, BALF, bronchoalveolar lavage fluid, Chlorocebus aethiops, Respiratory function, MOI, multiplicity of infection, Mice, Inbred BALB C, biology, HIV, human immunodeficiency virus, H & E, Hematoxylin and eosin, Treatment Outcome, CPE, cytopathic effect, 030220 oncology & carcinogenesis, COVID-19, Coronavirus Disease 2019, Flavanones, Scutellaria baicalensis, Female, ANOVA, Analysis of variance, Inflammation Mediators, LLOQ, lower limit of quantitation, Acute Lung Injury, JEV, Japanese encephalitis virus, Mice, Transgenic, Lung injury, Cavg, average steady-state plasma concentration, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, 03 medical and health sciences, EC50, half-maximal effective concentrations, In vivo, medicine, Animals, Cell damage, Vero Cells, ComputingMethodologies_COMPUTERGRAPHICS, Dose-Response Relationship, Drug, SARS-CoV-2, COVID-19, biology.organism_classification, medicine.disease, Baicalein, In vitro, Penh, enhanced pause, Rats, COVID-19 Drug Treatment, CC50, half-cytotoxic concentration, Mpro, main protease, 030104 developmental biology, chemistry, PEF, peak expiratory flow, Cmax, peak plasma concentration, hACE2, human angiotensin-converting enzyme 2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9405d794982bac469003939795bc7c15
http://europepmc.org/articles/PMC7588320

المؤلفون: Hao Wen, Wendong Li, Chunsheng Liu, Yong Liu, Ying Liu, Xiao-Qing Zhu, Ya Gao

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 4, Iss 2, Pp 161-166 (2014)
Acta Pharmaceutica Sinica B

مصطلحات موضوعية: LLOQ, lower limit of quantitation, BMMY, buffered methanol-complex medium, CNV, copy number variation, BMGY, buffered glycerol-complex medium, RSD, relative standard deviation, Mevalonic acid, Reductase, MM, minimal medium, law.invention, Pichia pastoris, HMGR, 3-hydroxy-3-methylglutaryl-CoA reductase, chemistry.chemical_compound, PCR, polymerase chain reaction, law, Botany, Glycyrrhiza uralensis Fisch, MD, minimal dextrose medium, General Pharmacology, Toxicology and Pharmaceutics, Triterpenoid saponin, chemistry.chemical_classification, Ergosterol, LOD, limit of detection, biology, Copy number variation, lcsh:RM1-950, Glycyrrhiza uralensis, biology.organism_classification, 3-Hydroxy-3-methylglutaryl-CoA reductase gene, lcsh:Therapeutics. Pharmacology, Enzyme, chemistry, Biochemistry, Over-expression, Recombinant DNA, Original Article, MVA, mevalonic acid, YPD, yeast peptone dextrose medium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5348d45e52d539b5873889e1a9634b
http://europepmc.org/articles/PMC4590296

المؤلفون: Pinkstaff J; BioMarin Pharmaceutical Inc., Novato, CA, USA., McCullagh E; BioMarin Pharmaceutical Inc., Novato, CA, USA., Grover A; BioMarin Pharmaceutical Inc., Novato, CA, USA., Melton AC; BioMarin Pharmaceutical Inc., Novato, CA, USA., Cherukuri A; BioMarin Pharmaceutical Inc., Novato, CA, USA., Wait JC; BioMarin Pharmaceutical Inc., Novato, CA, USA., Nguyen A; BioMarin Pharmaceutical Inc., Novato, CA, USA., Butt MT; StageBio, Mt. Jackson, VA, USA., Trombley JL; Northern Biomedical Research Inc., Norton Shores, MI, USA., Reed RP; Northern Biomedical Research Inc., Norton Shores, MI, USA., Adams EL; Northern Biomedical Research Inc., Norton Shores, MI, USA., Boyd RB; Northern Biomedical Research Inc., Norton Shores, MI, USA., Chandra S; BioMarin Pharmaceutical Inc., Novato, CA, USA., Henshaw J; BioMarin Pharmaceutical Inc., Novato, CA, USA., O'Neill CA; BioMarin Pharmaceutical Inc., Novato, CA, USA., Zanelli E; Allievex Corporation, Marblehead, MA, USA., Kovalchin J; Allievex Corporation, Marblehead, MA, USA.

المصدر: Toxicology reports [Toxicol Rep] 2023 Mar 01; Vol. 10, pp. 357-366. Date of Electronic Publication: 2023 Mar 01 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Internet ISSN: 2214-7500 (Electronic) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE

المؤلفون: Kim K; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee H; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee JJ; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Cha K; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Hyun Park N; Bio-Medical Science Co., Ltd, Seoul, Republic of Korea., Shin YK; Waters Korea Ltd, Seoul, Republic of Korea., Chae H; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Oh EJ; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

المصدر: Journal of mass spectrometry and advances in the clinical lab [J Mass Spectrom Adv Clin Lab] 2023 Jan 05; Vol. 27, pp. 56-60. Date of Electronic Publication: 2023 Jan 05 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101776811 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-145X (Electronic) Linking ISSN: 2667145X NLM ISO Abbreviation: J Mass Spectrom Adv Clin Lab Subsets: PubMed not MEDLINE