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المؤلفون: Suman Nag, Ming Yu, Sampath K. Gollapudi, Qing-Fen Gan
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Benzylamines, HCM, hypertrophic cardiomyopathy, HMM, heavy meromyosin, DMSO, dimethyl sulfoxide, Biochemistry, synthetic thick filaments (STFs), MyBPC, myosin-binding protein C, interacting-heads motif (IHM), Myosin head, Adenosine Triphosphate, Myosin, Phosphorylation, Super-Relaxed State (SRX), education.field_of_study, Heavy meromyosin, Chemistry, Cardiac muscle, Editors' Pick, medicine.anatomical_structure, Research Article, Myosin light-chain kinase, Myosin Light Chains, Population, macromolecular substances, Myosins, IHM, interacting-heads motif, 03 medical and health sciences, LMM, light meromyosin, Bc, bovine cardiac, medicine, Molecular motor, RLC, regulatory light chain, Animals, Humans, mavacamten, education, Muscle, Skeletal, Uracil, Molecular Biology, S2, subfragment 2, SRX, super-relaxed, 030102 biochemistry & molecular biology, DRX, disordered relaxed, Myosin Subfragments, R403Q, Cell Biology, Myocardial Contraction, S1, subfragment 1, 030104 developmental biology, STFs, synthetic thick filaments, Biophysics, ELC, essential light chain
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0bfbff28fa0b211d2a00a4347e7626
http://europepmc.org/articles/PMC7948491 -
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المؤلفون: Matthew Batchelor, Peter J. Knight, Michelle Peckham, Ruth E. Hughes, Francine Parker, Marcin Wolny
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: 0301 basic medicine, muscle, Muscle Fibers, Skeletal, myosin, medicine.disease_cause, Sarcomere, GST, glutathione S-transferase, Protein Structure, Secondary, Mice, MRE, mean residue ellipticity, Structural Biology, Myosin, CD, circular dichroism, Coiled coil, Mutation, Meromyosin, Chemistry, Myogenesis, MPD-1, Laing early-onset distal myopathy, MD, molecular dynamics, 3. Good health, Cell biology, medicine.anatomical_structure, medicine.symptom, myopathy, Sarcomeres, β-MHC, β-cardiac myosin heavy chain, In Vitro Techniques, Molecular Dynamics Simulation, Article, RMSF, root mean square fluctuation, Cell Line, 03 medical and health sciences, LMM, light meromyosin, medicine, Animals, Myopathy, Molecular Biology, EM, electron microscopy, coiled coil, Myosin Heavy Chains, Skeletal muscle, mutations, WT, wild-type, Rats, Distal Myopathies, Microscopy, Electron, 030104 developmental biology, Cardiac Myosins
وصف الملف: application/pdf
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المؤلفون: Michael J. Greenberg, Samantha K. Barrick
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: cardiac muscle, S2, subfragment-2, DRX, disordered relaxed state, HCM, hypertrophic cardiomyopathy, cardiac development, OM, omecamtiv mecarbil, HMM, heavy meromyosin, myosin, heart, macromolecular substances, contractile protein, Mechanotransduction, Cellular, Biochemistry, Contractility, LMM, light meromyosin, cMyBP-C, cardiac myosin-binding protein C, ATP hydrolysis, Myosin, RLC, regulatory light chain, medicine, Molecular motor, Animals, Humans, Mechanotransduction, DCM, dilated cardiomyopathy, Molecular Biology, mechanotransduction, Heart Failure, hiPSC-CM, human induced pluripotent stem cell–derived cardiomyocyte, Chemistry, JBC Reviews, Myocardium, IHM, interacting heads motif, Cardiac muscle, Cell Biology, medicine.disease, Myocardial Contraction, S1, subfragment-1, SRX, super relaxed state, medicine.anatomical_structure, Heart failure, medicine.symptom, cardiomyopathy, Cardiac Myosins, Neuroscience, ELC, essential light chain, MHC, myosin heavy chain, Muscle contraction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618af3dcd76ba61655a8927e701d2a4
https://doi.org/10.1016/j.jbc.2021.101297
