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المؤلفون: Goshi Shiota, Hiroyuki Tsuchiya
المصدر: Tsuchiya, Hiroyuki. Shiota, Goshi. Immune evasion by cancer stem cells. Regenerative Therapy. 17. 20-33. doi:10.1016/j.reth.2021.02.006
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapyمصطلحات موضوعية: PD-L1/2, ligands 1/2, 0301 basic medicine, Medicine (General), Immune checkpoint inhibitors, Cell, LAG3, lymphocyte activation gene 3, Review, NK cells, Tumor initiation, HNSCC, head and neck squamous cell carcinoma, MIC, MHC class I polypeptide-related sequence, DC, dendritic cell, 0302 clinical medicine, AML, acute myeloid leukemia, ARID3B, AT-rich interaction domain-containing protein 3B, OCT4, octamer-binding transcription factor 4, TCR, T cell receptor, Cancer stem cells, Immune evasion, CCR7, C–C motif chemokine receptor 7, KDM4, lysine-specific demethylase 4C, medicine.anatomical_structure, TAM, tumor-associated macrophage, EMT, epithelial–mesenchymal transition, NK, natural killer, ULBP, UL16 binding protein, LILR, leukocyte immunoglobulin-like receptor, NGF, nerve growth factor, T cells, Biomedical Engineering, Treg, regulatory T cell, Tumor immunity, CTL, cytotoxic T lymphocytes, NOD, nonobese diabetic, Biomaterials, 03 medical and health sciences, R5-920, Immune system, ALDH, alcohol dehydrogenase, EV, extracellular vesicle, MDSC, myeloid-derived suppressor cell, Cancer stem cell, medicine, MHC, major histocompatibility complex, KIR, killer immunoglobulin-like receptor, TAP, transporter associated with antigen processing, SCID, severe combined immunodeficient, QH573-671, business.industry, LMP, low molecular weight protein, CIK, cytokine-induced killer cell, LOX, lysyl oxidase, CTLA-4, cytotoxic T-cell-associated antigen-4, CMV, cytomegalovirus, SOX2, sex determining region Y-box 2, NSG, NOD/SCID IL-2 receptor gamma chain null, Evasion (ethics), CSC, cancer stem cell, 030104 developmental biology, DNMT, DNA methyltransferase, Cancer cell, Immune checkpoints, Cancer research, PI9, protease inhibitor 9, ADCC, antibody-dependent cell mediated cytotoxicity, uPAR, urokinase-type plasminogen activator receptor, Cytology, business, ETO, fat mass and obesity associated protein, 030217 neurology & neurosurgery, PD-1, programmed death receptor-1, PSME3, proteasome activator subunit 3, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Karan M. Shah, Elena Adinolfi, Elena De Marchi, Archana Singh, Luke Tattersall, Alex Williamson, Jennifer M. Down, William D. Fraser, Alison Gartland, Francesco Di Virgilio, Michelle A. Lawson, Dominique Heymann, Darren Lath, Darrell Green
المساهمون: University of Sheffield [Sheffield], University of East Anglia [Norwich] (UEA), Università degli Studi di Ferrara = University of Ferrara (UniFE), Institut de Cancérologie de l'Ouest [Angers/Nantes] (UNICANCER/ICO), UNICANCER, Norwich University, Heymann, Dominique
المصدر: Journal of Bone Oncology
Journal of Bone Oncology, 2021, 31, pp.100398. ⟨10.1016/j.jbo.2021.100398⟩
Journal of Bone Oncology, Vol 31, Iss, Pp 100398-(2021)مصطلحات موضوعية: FDR : False Discovery Rate, Diseases of the musculoskeletal system, EMT : Epithelial–mesenchymal transition, [SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], Metastasis, OS : Osteosarcoma, PE : Paired End, ATP : Adenosine Triphosphate, Purinergic signalling, BzATP : Benzoyl ATP, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], Bone cancer, RC254-282, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Osteosarcoma, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, PDGFB, Purinergic receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Transfection, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, DE : Differentially Expressed, Oncology, ECM : Extracellular Matrix, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, [SDV.MHEP.AHA] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, LOX : Lysyl Oxidase, [SDV.MHEP.PED] Life Sciences [q-bio]/Human health and pathology/Pediatrics, [SDV.CAN] Life Sciences [q-bio]/Cancer, In vivo, medicine, HBSS : Hanks Balanced Salt Solution, [SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], MMPs : Matrix Metalloproteinases, Cell adhesion, P2RX7B, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, business.industry, Ambientale, Cancer, P2RX7, medicine.disease, ATP, qRT-PCR : Quantitative Reverse Transcription Polymerase Chain Reaction, RC925-935, Cancer research, business
وصف الملف: application/pdf
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المؤلفون: Weiying Zhang, Xueli Fu, Bowen Liu, Lu Zhang, Lihong Ye, Xue Wang, Tianjiao Wang, Kai Ye, Feifei Xu, Tianzhi Jin, Yue Wu
المصدر: EBioMedicine
مصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Research paper, Carcinogenesis, ASA, aspirin, PDTC, pyrrolidine dithiocarbamate, LMCD1-AS1, medicine.disease_cause, TNF-α, tumour necrosis factor-α, NF-κB, Extracellular matrix, Mice, 0302 clinical medicine, Cell Movement, TCGA, the cancer genome atlas, ncRNAs, non-coding RNAs, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, Liver Neoplasms, Let-7g, NF-kappa B, General Medicine, ECM, extracellular matrix, Blot, ChIP, chromatin immunoprecipitation, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, RNA, Long Noncoding, Collagen, P4HA2, collagen prolyl 4-hydroxylase A subunit 2, MTT, methyl thiazolyl tetrazolium, China, DMSO, dimethylsulfoxide, Carcinoma, Hepatocellular, IHC, immunohistochemical, Lysyl oxidase, miRNAs, microRNA, Collagen deposition, General Biochemistry, Genetics and Molecular Biology, Prolyl Hydroxylases, 03 medical and health sciences, Col IV, collagen type IV, Cell Line, Tumor, microRNA, medicine, Animals, Humans, IF, immunofluorescence, Viability assay, Col I, collagen type I, Cell Proliferation, P4HA2, Aspirin, business.industry, medicine.disease, Lox, lysyl oxidase, Xenograft Model Antitumor Assays, MicroRNAs, 030104 developmental biology, siRNA, small interfering RNA, Cancer research, lncRNA, long noncoding RNA, business, HCC, hepatocellular carcinoma, Protein Processing, Post-Translational
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المؤلفون: Michael P, Murphy, Justin R, King, Katherin E, Leckie
المصدر: JACC: Basic to Translational Science
مصطلحات موضوعية: Jak/Stat, p, phosphorylated, WT, wild type, KO, knockout, Stat, signal transducer and activator of transcription, AD, aortic dissection, AngII, angiotensin II, SMA, smooth muscle α-actin, SMC, smooth muscle cell, BAPN, β-aminopropionitrile, SMemb, embryonic isoform of myosin heavy chain, Jnk, c-Jun N-terminal kinases, SM2, smooth muscle myosin heavy chain, Lox, lysyl oxidase, Socs, suppressor of cytokine signaling, smooth muscle cells, ECM, extracellular matrix, IL, interleukin, smSocs3-KO, knockout of the smooth muscle cell Socs3, PRECLINICAL RESEARCH, inflammation, aortic dissection
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المؤلفون: Stacy K. Thomas, Gregory L. Beatty, Jesse Lee
المصدر: EBioMedicine
EBioMedicine, Vol 53, Iss, Pp-(2020)مصطلحات موضوعية: 0301 basic medicine, LIF, leukaemia inhibitory factor, Neutrophils, PDAC, pancreatic ductal adenocarcinoma, lcsh:Medicine, EMT, epithelial to mesenchymal transition, PSC, pancreatic stellate cells, Wnt1, Wnt family member 1, PDGF, platelet-derived growth factor, Metastasis, Prxx1, paired-related homeodomain transcription factor 1, Pancreatic ductal adenocarcinoma, MIF, macrophage migration inhibitory factor, 0302 clinical medicine, Clinical trials, DNA, deoxyribonucleic acid, CXCL, C-X-C motif chemokine ligand, SAA, serum amyloid A, Medicine, TGF, transforming growth factor, TMEM, tumor microenvironments of metastasis, Series, Cancer, lcsh:R5-920, Vaccines, CXCR, CXC chemokine receptor, PDGFR, platelet-derived growth factor receptor, TNF, tumor necrosis factor, Immune evasion, General Medicine, Primary tumor, Treatment paradigms, MET, mesenchymal-to-epithelial transition, MMP, matrix metalloproteinase, Tumor microenvironment, 030220 oncology & carcinogenesis, Immunotherapy, lcsh:Medicine (General), PI3K, phosphoinositide 3-kinase, TLR, Toll-like receptor, T cells, Zeb1, zinc finger E-box-binding homeobox 1, General Biochemistry, Genetics and Molecular Biology, SIRP, signal regulatory protein, STAT3, signal transducer and activation of transcription, 03 medical and health sciences, Paracrine signalling, DCC, disseminated cancer cell, Pancreatic cancer, CSF, colony stimulating factor, CCR, C-C chemokine receptor, Humans, Epithelial–mesenchymal transition, CAF, cancer-associated fibroblasts, Inflammation, EGF, epidermal growth factor, business.industry, Macrophages, lcsh:R, Immunosurveillance, LOX, lysyl oxidase, PanIN, pancreatic intraepithelial neoplasia, Therapeutic resistance, TIMP, tissue inhibitor matrix metalloproteinase, medicine.disease, TRAIL-R, TNF-related apoptosis-inducing ligand receptor, IL, interleukin, Pancreatic Neoplasms, 030104 developmental biology, Cancer cell, Cancer research, business
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المؤلفون: Ward, Matthew, Iskratsch, Thomas
المصدر: Biochimica et Biophysica Acta. Molecular Cell Research
مصطلحات موضوعية: ICM, Idiopathic cardiomyopathy, HLCCs, Hylald-derived collagen crosslinks, HCM, hypertrophic cardiomyopathy, Heart Diseases, DCM, Dilated cardiomyopathy, PKC, Protein Kinase C, GEF, Guanine nucleotide exchange factor, LV, Left ventricle, MRTF, myocardin-related transcription factor, Mechanotransduction, Cellular, Article, VASH1, vasohibin-1, LCCs, Lysald-derived collagen crosslinks, LH, Lysyl hydroxylase, PKA, Protein Kinase A, Humans, Myocytes, Cardiac, MRE, magnetic resonance elastography, Cell Proliferation, TNNT, Troponin T, SWE, ultrasound cardiac shear-wave elastography, Cell Death, LOX, Lysyl oxidase, TCP, tubulin carboxypeptidase, SVBP, small vasohibin binding protein, Lys, Lysin, Cell Differentiation, Heart, TNNI, Troponin I, AFM, atomic force microscope, LOXL, Lysyl oxidase like protein, CM, Cardiomyocytes, MYH, Myosin Heavy Chain, TTL, tubulin tyrosine ligase, Cellular Microenvironment, GAP, GTPase activating protein
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المؤلفون: Aneesh K. Ramaswamy, Katherine L. Lorentz, David A. Vorp, Justin S. Weinbaum, Rachel E. Sides, Leila M. Reines, Eoghan M. Cunnane
المصدر: Matrix Biology Plus, Vol 4, Iss, Pp-(2019)
Matrix Biology Plusمصطلحات موضوعية: SMC, smooth muscle cell, LTBP, latent TGF-β binding protein, 030204 cardiovascular system & hematology, Biochemistry, Extracellular matrix, Aortic aneurysm, 0302 clinical medicine, lcsh:QH301-705.5, Aorta, 0303 health sciences, biology, Tropoelastin, integumentary system, Chemistry, LOXL-1, LOX-like 1, ASC, adipose-derived stromal cell, ECM, extracellular matrix, Cell biology, medicine.anatomical_structure, RT, reverse transcriptase, cardiovascular system, qPCR, quantitative polymerase chain reaction, Elastic fiber, ACA, epsilon-amino caproic acid, Histology, Stromal cell, Biophysics, Lysyl oxidase, Article, 03 medical and health sciences, FBS, fetal bovine serum, NCM, non-conditioned media, PBS, phosphate buffered saline, TGF-β, transforming growth factor-β, AA, aortic aneurysm, Genetics, medicine, Extracellular, Molecular Biology, 030304 developmental biology, LOX, lysyl oxidase, Cell Biology, ASC-SF, ASC secreted factors, medicine.disease, Aneurysm, Vascular regeneration, Elastin, NT, no treatment, lcsh:Biology (General), biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd7d4e17f66cc01c499b27884dc4021
http://www.sciencedirect.com/science/article/pii/S2590028519300134 -
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المؤلفون: Feneck, Eleanor M., Lewis, Philip N., Ralphs, Jim, Meek, Keith M.
المصدر: Experimental Eye Research
مصطلحات موضوعية: Adult, Male, genetic structures, Fibrillin-1, Corneal Stroma, Article, Cornea, Mice, IOP, Intraocular pressure, Trabecular Meshwork, Animals, Humans, PBST, phosphate buffered saline tween-20, MAGP, Microfibril-associated glycoproteins, Descemet Membrane, Aged, SBF-SEM, Serial block face scanning electron microscopy, TEM, Transmission electron microscopy, LOX, Lysyl oxidase, TPEM, Two-photon excitation microscopy, Glaucoma, Elastic Tissue, eye diseases, Elastin, TGF-β, Transforming growth factor beta, Mice, Inbred C57BL, Elastic fibres, POAG, Primary open angle glaucoma, Female, sense organs, MFS, Marfan syndrome
وصف الملف: application/pdf
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المؤلفون: Jessica Bauer, Yasna Jain, Taher A. Saif, Barbara Jung, Bashar Emon
المصدر: Computational and Structural Biotechnology Journal, Vol 16, Iss, Pp 279-287 (2018)
Computational and Structural Biotechnology Journalمصطلحات موضوعية: 0301 basic medicine, EMT, Epithelial to mesenchymal transition, VEGF, Vascular endothelial growth factor, TACs, Tumor-associated collagen signatures, IGFs, Insulin-like growth factors, IL-13, Interleukin-13, Review Article, LOX, Lysyl Oxidase, Biochemistry, Metastasis, SDF-1/CXCL12, Stromal cell-derived factor 1/C-X-C motif chemokine 12, Extracellular matrix, α-SMA, α-Smooth muscle actin, 0302 clinical medicine, Structural Biology, TNF-α, Tumor necrosis factor-α, HGF/SF, Hepatocyte growth factor/Scatter factor, Cancer, CSF-1, Colony stimulating factor 1, MMPs, Matrix metalloproteinases, 3. Good health, Computer Science Applications, Tumor biophysics, EGF, Epidermal growth factor, 030220 oncology & carcinogenesis, CAF, Cancer associated fibroblast, ECM stiffness, Growth factors, Biotechnology, Stromal cell, KGF, Keratinocyte growth factor, also FGF7, lcsh:Biotechnology, CYR61/CCN1, Cysteine-rich angiogenic inducer 61/CCN family member 1, Biophysics, Cancer metastasis, NO, Nitric oxide, 03 medical and health sciences, ECM, Extracellular matrix, IL-33, Interleukin-33, Stroma, lcsh:TP248.13-248.65, TGFβ, Transforming growth factor β, Genetics, medicine, IL-6, Interleukin-6, Tumor microenvironment, business.industry, technology, industry, and agriculture, medicine.disease, Activin/TGFβ, 030104 developmental biology, ADAMs, Adamalysins, CTGF, Connective tissue growth factor, Cancer cell, Cancer research, ANGPT2, Angiopoietin 2, business, FGF, Fibroblast growth factor
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المؤلفون: Goggins, Eibhlin, Kakkad, Samata, Mironchik, Yelena, Jacob, Desmond, Wildes, Flonne, Krishnamachary, Balaji, Bhujwalla, Zaver M.
المصدر: Neoplasia (New York, N.Y.)
مصطلحات موضوعية: Original article, Col1, Collagen I, SMA, Smooth Muscle Actin, MT-MMP, Membrane-Type Matrix Metalloproteinase, Apoptosis, Triple Negative Breast Neoplasms, SHG, Second Harmonic Generation, qRT-PCR, Quantitative Real Time Polymerase Chain Reaction, LOX, Lysyl Oxidase, TNBC, Triple Negative Breast Cancer, Collagen Type I, Protein-Lysine 6-Oxidase, Mice, DAB, 3,3′-diaminobenzedine, Basic Helix-Loop-Helix Transcription Factors, Biomarkers, Tumor, Tumor Cells, Cultured, Tumor Microenvironment, Animals, Humans, ECM, Extracellular Matrix, Cell Proliferation, TME, Tumor Microenvironment, Elastic Tissue, Hypoxia-Inducible Factor 1, alpha Subunit, Xenograft Model Antitumor Assays, MMP, Matrix Metalloproteinase, Cell Hypoxia, Gene Expression Regulation, Neoplastic, P4H, Prolyl Hydroxylase, DS, Double Silenced, HIF, Hypoxia Inducible Factor, H&E, Hematoxylin and eosin, Female