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المؤلفون: Nandi P; School of Molecular Sciences, Arizona State University, Tempe, AZ, USA.; Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, USA.; Biology Department, Brookhaven National Laboratory, Upton, NY, USA., DeVore K; School of Molecular Sciences, Arizona State University, Tempe, AZ, USA.; Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, USA., Wang F; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Li S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Walker JD; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA., Truong TT; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA.; Faculty of Pharmacy, Phenikaa University, Hanoi, Vietnam., LaPorte MG; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA., Wipf P; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA., Schlager H; Curia Global, Albany, NY, USA., McCleerey J; Curia Global, Albany, NY, USA.; Graduate School of Arts and Sciences, Boston University, Boston, MA, USA., Paquette W; Curia Global, Albany, NY, USA., Columbres RCA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.; Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, USA., Gan T; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Poh YP; Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, USA.; Biodesign Center for Mechanism of Evolution, Arizona State University, Tempe, AZ, USA., Fromme P; School of Molecular Sciences, Arizona State University, Tempe, AZ, USA.; Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, USA., Flint AJ; Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Wolf M; Curia Global, Albany, NY, USA., Huryn DM; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Chou TF; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. tfchou@caltech.edu.; Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, CA, USA. tfchou@caltech.edu., Chiu PL; School of Molecular Sciences, Arizona State University, Tempe, AZ, USA. plchiu@asu.edu.; Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, USA. plchiu@asu.edu.

المصدر: Communications chemistry [Commun Chem] 2024 Aug 09; Vol. 7 (1), pp. 177. Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101725670 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3669 (Electronic) Linking ISSN: 23993669 NLM ISO Abbreviation: Commun Chem Subsets: PubMed not MEDLINE

المؤلفون: LaPorte MG; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Alverez C; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Chatterley A; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Kovaliov M; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Carder EJ; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Houghton MJ; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Lim C; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Miller ER; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Samankumara LP; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Liang M; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Kerrigan K; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Yue Z; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Li S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States., Tomaino F; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Wang F; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States., Green N; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Stott GM; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Srivastava A; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Chou TF; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States., Wipf P; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Huryn DM; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Jun 21; Vol. 14 (7), pp. 977-985. Date of Electronic Publication: 2023 Jun 21 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Charaschanya M; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Maskrey TS; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., LaPorte MG; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Janjic JM; Pharmaceutical Sciences, Duquesne University School of Pharmacy, 415 Mellon Hall, Pittsburgh, Pennsylvania 15282, United States.; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Wipf P; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2022 Feb 04; Vol. 13 (3), pp. 403-408. Date of Electronic Publication: 2022 Feb 04 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Sen M; Department of Hematology/Oncology, UPMC Hillman Cancer Center , Pittsburgh, PA, USA., Kindsfather A; Department of Hematology/Oncology, UPMC Hillman Cancer Center , Pittsburgh, PA, USA., Danilova L; Department of Oncology, Laboratory of Systems Biology and Computational Genetics, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore, MD, USA.; Vavilov Institute of General Genetics, Russian Academy of Sciences , Moscow, Russia., Zhang F; Chemical Diversity Center, University of Pittsburgh , Pittsburgh, PA, USA., Colombo R; Chemical Diversity Center, University of Pittsburgh , Pittsburgh, PA, USA., LaPorte MG; Chemical Diversity Center, University of Pittsburgh , Pittsburgh, PA, USA., Kurland BF; Department of Biostatistics, University of Pittsburgh , Pittsburgh, PA, USA., Huryn DM; Chemical Diversity Center, University of Pittsburgh , Pittsburgh, PA, USA., Wipf P; Chemical Diversity Center, University of Pittsburgh , Pittsburgh, PA, USA., Herman JG; Department of Hematology/Oncology, UPMC Hillman Cancer Center , Pittsburgh, PA, USA.

المصدر: Epigenetics [Epigenetics] 2020 Jun - Jul; Vol. 15 (6-7), pp. 604-617. Date of Electronic Publication: 2019 Oct 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Gene Silencing*, Carcinoma, Non-Small-Cell Lung/*genetics , Lung Neoplasms/*genetics , Receptor-Like Protein Tyrosine Phosphatases, Class 2/*genetics , STAT3 Transcription Factor/*metabolism, A549 Cells ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Promoter Regions, Genetic ; Receptor-Like Protein Tyrosine Phosphatases, Class 2/metabolism ; bcl-X Protein/genetics ; bcl-X Protein/metabolism

المؤلفون: LaPorte MG; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Burnett JC; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Computational Drug Development Group, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892, United States., Colombo R; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Bulfer SL; Department of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, California 94158, United States., Alverez C; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Chou TF; Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90502, United States., Neitz RJ; Department of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, California 94158, United States., Green N; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Moore WJ; Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States., Yue Z; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Li S; Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90502, United States., Arkin MR; Department of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, California 94158, United States., Wipf P; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Huryn DM; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Sep 18; Vol. 9 (11), pp. 1075-1081. Date of Electronic Publication: 2018 Sep 18 (Print Publication: 2018).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Burnett JC; Leidos Biomedical Research, Inc., P.O. Box B, Frederick, MD 21702, USA., Lim C, Peyser BD, Samankumara LP, Kovaliov M, Colombo R, Bulfer SL, LaPorte MG, Hermone AR, McGrath CF, Arkin MR, Gussio R, Huryn DM, Wipf P

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2017 May 16; Vol. 15 (19), pp. 4096-4114.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Allosteric Site* , Hydrophobic and Hydrophilic Interactions* , Threonine*, Adenosine Triphosphatases/*chemistry , Adenosine Triphosphatases/*metabolism , Nuclear Proteins/*chemistry , Nuclear Proteins/*metabolism, Amino Acid Motifs ; Ligands ; Models, Molecular ; Protein Binding

المؤلفون: LaPorte MG; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA., Wang Z; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Colombo R; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA., Garzan A; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA., Peshkov VA; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA., Liang M; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Johnston PA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA., Schurdak ME; University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA; University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA., Sen M; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Camarco DP; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Hua Y; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA., Pollock NI; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Lazo JS; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Grandis JR; Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA 94158, USA., Wipf P; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA; University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA., Huryn DM; University of Pittsburgh Chemical Diversity Center, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Aug 01; Vol. 26 (15), pp. 3581-5. Date of Electronic Publication: 2016 Jun 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Pyrazoles/*pharmacology , STAT3 Transcription Factor/*antagonists & inhibitors , Thiadiazines/*pharmacology , Triazoles/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Pyrazoles/chemistry ; STAT3 Transcription Factor/metabolism ; Structure-Activity Relationship ; Thiadiazines/chemical synthesis ; Thiadiazines/chemistry ; Triazoles/chemical synthesis ; Triazoles/chemistry