المؤلفون: Li F; Department of Radiology, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, USA., Fan Y; Division of Physical Science & Processing Technology, Brazosport College, Lake Jackson, TX, USA., Zhou L; Department of Pathology and Genomic Medicine, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, USA., Martin DR; Department of Radiology, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, USA., Liu Z; Department of Radiology, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, USA. Electronic address: zliu2@houstonmethodist.org., Li Z; Department of Radiology, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, USA. Electronic address: Zheng.li3@nih.gov.

المصدر: Nuclear medicine and biology [Nucl Med Biol] 2024 Sep-Oct; Vol. 136-137, pp. 108929. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9304420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9614 (Electronic) Linking ISSN: 09698051 NLM ISO Abbreviation: Nucl Med Biol Subsets: MEDLINE

مواضيع طبية MeSH: HSP90 Heat-Shock Proteins*/metabolism , HSP90 Heat-Shock Proteins*/antagonists & inhibitors , Copper Radioisotopes* , Breast Neoplasms*/diagnostic imaging , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Lactams, Macrocyclic*/chemical synthesis , Lactams, Macrocyclic*/chemistry , Lactams, Macrocyclic*/pharmacology , Benzoquinones*/chemistry, Animals ; Humans ; Mice ; Female ; Isotope Labeling ; Cell Line, Tumor ; Tissue Distribution ; Chemistry Techniques, Synthetic ; Gene Expression Regulation, Neoplastic ; Radiochemistry ; Positron-Emission Tomography/methods ; Cricetulus

المؤلفون: Lima CR; Laboratory of Biological System Modeling, Centro de Desenvolvimento Tecnológico em Saúde (CDTS), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., Antunes D; Laboratório de Genômica Aplicada e Bioinovações, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., Caffarena E; Grupo de Biofísica Computacional e Modelagem Molecular, Programa de Computação Científica (PROCC), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, Brazil., Carels N; Laboratory of Biological System Modeling, Centro de Desenvolvimento Tecnológico em Saúde (CDTS), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro 21040-900, Brazil.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 12; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Lactams, Macrocyclic*/pharmacology , Lactams, Macrocyclic*/chemistry , Ritonavir*/chemistry , Ritonavir*/pharmacology , Benzoquinones*/chemistry , Benzoquinones*/pharmacology , Benzoquinones*/metabolism , HSP90 Heat-Shock Proteins*/chemistry , HSP90 Heat-Shock Proteins*/metabolism , HSP90 Heat-Shock Proteins*/antagonists & inhibitors, Humans ; Protein Binding ; Molecular Dynamics Simulation ; Molecular Docking Simulation ; Models, Molecular ; Binding Sites ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/chemistry

المؤلفون: Park JH; Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea., Kim SJ; Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.; Catholic Central Laboratory of Surgery, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.; Translational Research Team, Surginex Co., Ltd., Seoul 06591, Republic of Korea., Kim OH; Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.; Catholic Central Laboratory of Surgery, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea., Kim DJ; Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.; Catholic Central Laboratory of Surgery, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 12; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Exosomes*/metabolism , Stomach Neoplasms*/drug therapy , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/pathology , Benzoquinones*/pharmacology , Benzoquinones*/administration & dosage , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/administration & dosage , Antineoplastic Agents*/therapeutic use , Lactams, Macrocyclic*/pharmacology , Lactams, Macrocyclic*/administration & dosage , Lactams, Macrocyclic*/therapeutic use, Animals ; Mice ; Humans ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Drug Delivery Systems/methods ; Apoptosis/drug effects ; Mice, Nude

المؤلفون: Sato Y; Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan., Sato Y; DNA Chip Research Inc, Tokyo, Japan., Irie K; Department of Pharmaceutics, Faculty of Pharmaceutical Science, Kobe Gakuin University, Kobe, Japan., Nanjo S; Department of Respiratory Medicine, Kanazawa University Hospital, Kanazawa, Japan., Hara S; Department of Pathology, Kobe City Medical Center General Hospital, Kobe, Japan., Fujiwara S; Department of Neurology, Kobe City Medical Center General Hospital, Kobe, Japan., Tomii K; Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.

المصدر: Thoracic cancer [Thorac Cancer] 2024 Aug; Vol. 15 (23), pp. 1772-1775. Date of Electronic Publication: 2024 Jun 24.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-7714 (Electronic) Linking ISSN: 17597706 NLM ISO Abbreviation: Thorac Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Organophosphorus Compounds*/therapeutic use , Organophosphorus Compounds*/pharmacology , Organophosphorus Compounds*/administration & dosage , Lactams*/therapeutic use , Aminopyridines*/therapeutic use , Aminopyridines*/pharmacology , Anaplastic Lymphoma Kinase*/genetics , Pyrimidines*/therapeutic use , Pyrimidines*/pharmacology , Pyrimidines*/administration & dosage , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Lactams, Macrocyclic*/therapeutic use , Lactams, Macrocyclic*/pharmacology , Adenocarcinoma of Lung*/drug therapy , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/genetics , Drug Resistance, Neoplasm* , Pyrazoles*/therapeutic use , Pyrazoles*/pharmacology , Carbazoles*/therapeutic use , Carbazoles*/pharmacology , Carbazoles*/administration & dosage , Piperidines*/therapeutic use , Piperidines*/pharmacology, Humans ; Male ; Adult ; Brain Neoplasms/drug therapy ; Brain Neoplasms/secondary

المؤلفون: Gupta R; Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali, Punjab 140306, India.; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States., Chauhan A; Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali, Punjab 140306, India.; Special Centre for Nanoscience, Jawaharlal Nehru University, New Delhi 110067, India., Kaur T; Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali, Punjab 140306, India., Kuanr BK; Special Centre for Nanoscience, Jawaharlal Nehru University, New Delhi 110067, India., Sharma D; Institute of Nano Science and Technology, Knowledge City, Sector 81, Mohali, Punjab 140306, India.

المصدر: ACS nano [ACS Nano] 2024 Jul 02; Vol. 18 (26), pp. 17145-17161. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

مواضيع طبية MeSH: HSP90 Heat-Shock Proteins*/antagonists & inhibitors , HSP90 Heat-Shock Proteins*/metabolism , Glioma*/therapy , Glioma*/pathology , Glioma*/immunology , Glioma*/drug therapy , Hyperthermia, Induced* , Lactams, Macrocyclic*/pharmacology , Lactams, Macrocyclic*/chemistry , Benzoquinones*/pharmacology , Benzoquinones*/chemistry, Animals ; Mice ; Humans ; Cell Line, Tumor ; Cell Survival/drug effects ; Tumor Microenvironment/drug effects

المؤلفون: Suwannalert P; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.; Pathobiology Information and Learning Center, Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Panpinyaporn P; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Wantanachaisaeng P; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Teeppaibul T; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Worawichitchaikun T; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Koomsang T; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.; Pathobiology Information and Learning Center, Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Naktubtim C; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.; Pathobiology Information and Learning Center, Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand., Payuhakrit W; Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand; witchuda.pay@mahidol.ac.th.; Pathobiology Information and Learning Center, Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.

المصدر: In vivo (Athens, Greece) [In Vivo] 2024 Sep-Oct; Vol. 38 (5), pp. 2228-2238.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8806809 Publication Model: Print Cited Medium: Internet ISSN: 1791-7549 (Electronic) Linking ISSN: 0258851X NLM ISO Abbreviation: In Vivo Subsets: MEDLINE

مواضيع طبية MeSH: Benzoquinones*/pharmacology , Lactams, Macrocyclic*/pharmacology , Apoptosis*/drug effects , Breast Neoplasms*/genetics , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/metabolism , Endoplasmic Reticulum Stress*/drug effects , Eukaryotic Initiation Factor-2*/metabolism , Eukaryotic Initiation Factor-2*/genetics , eIF-2 Kinase*/metabolism , eIF-2 Kinase*/genetics, Humans ; Female ; Cell Line, Tumor ; HSP90 Heat-Shock Proteins/metabolism ; HSP90 Heat-Shock Proteins/genetics ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Up-Regulation/drug effects

المؤلفون: Illendula S; Research scholar, Department of Pharmacy, Shyam university, Dausa-303511, Rajasthan, India., Sharma S; Principal and Professor, Department of Pharmacy, Shyam university, Dausa-303511, Rajasthan, India.

المصدر: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2024 Aug 20; Vol. 40, pp. e20240009. Date of Electronic Publication: 2024 Aug 20.

نوع المنشور: Journal Article; Validation Study

بيانات الدورية: Publisher: Zhongguo ying yong sheng li xue za zhi bian ji bu Country of Publication: China NLM ID: 9426407 Publication Model: Electronic Cited Medium: Print ISSN: 1000-6834 (Print) Linking ISSN: 10006834 NLM ISO Abbreviation: Zhongguo Ying Yong Sheng Li Xue Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Lactams* , Aminopyridines*/analysis , Pyrazoles*/analysis , Lactams, Macrocyclic*, Chromatography, High Pressure Liquid/methods

المؤلفون: Shih JY; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: jyshih@ntu.edu.tw., Luo YH; Taipei Veterans General Hospital, Taipei, Taiwan., Chang GC; School of Medicine, and Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan; Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Chang JW; Chang Gung Memorial Hospital- Linko, Taoyuan, Taiwan., Wang CC; Divisions of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Chang Gung University College of Medicine, Kaohsiung, Taiwan., Yang TY; Taichung Veterans General Hospital, Taichung, Taiwan., Fang WT; Pfizer, Taiwan., Shau WY; Pfizer, Taiwan.

المصدر: Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2024 Aug; Vol. 123 (8), pp. 875-881. Date of Electronic Publication: 2024 Jan 09.

نوع المنشور: Journal Article; Observational Study; Multicenter Study

بيانات الدورية: Publisher: Formosan Medical Association, Elsevier Country of Publication: Singapore NLM ID: 9214933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0929-6646 (Print) Linking ISSN: 09296646 NLM ISO Abbreviation: J Formos Med Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Lung Neoplasms*/drug therapy , Anaplastic Lymphoma Kinase*/antagonists & inhibitors , Aminopyridines*/therapeutic use , Lactams*/therapeutic use , Pyrazoles*/therapeutic use , Lactams, Macrocyclic*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Taiwan ; Adult ; Protein Kinase Inhibitors/therapeutic use

المؤلفون: Arriola E; Medical Oncology Department, Hospital del Mar, Center for Biomedical Network Research on Cancer (CIBERONC), Barcelona, Spain. earriola@psmar.cat., de Castro J; Medical Oncology Department, La Paz University Hospital, Hospital La Paz Health Research Institute (IdiPAZ), Center for Biomedical Network Research on Cancer (CIBERONC), Madrid, Spain., García-Campelo R; Medical Oncology Department, A Coruña University Hospital, Biomedical Research Institute of A Coruña (INIBIC), A Coruña, Spain., Bernárdez B; Oncological Pharmacy Unit, Santiago de Compostela University Clinical Hospital, Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela, A Coruña, Spain., Bernabé R; Medical Oncology Department, Virgen del Rocío University Hospital, Biomedicine Institute of Sevilla (IBIS), University of Sevilla, Sevilla, Spain., Bruna J; Neuro-Oncology Unit, Bellvitge University Hospital, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain., Dómine M; Medical Oncology Department, Fundación Jiménez Díaz University Hospital, Fundación Jiménez Díaz Health Research Institute (IIS-FJD), Autonomous University of Madrid, Madrid, Spain., Isla D; Medical Oncology Department, University Hospital Lozano Blesa, Health Research Institute of Aragon (IIS Aragón), Zaragoza, Spain., Juan-Vidal Ó; Medical Oncology Department, La Fe University and Polytechnic Hospital, Valencia, Spain., López-Fernández T; Cardiology Department, La Paz University Hospital, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain., Nadal E; Medical Oncology Department, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain., Rodríguez-Abreu D; Insular-Maternity and Pediatric University Hospital Complex of Gran Canaria, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain., Vares M; Internal Medicine Department, A Coruña University Hospital, A Coruña, Spain., Asensio Ú; Medical Department, Pfizer Oncology, Madrid, Spain., García LF; Medical Department, Pfizer Oncology, Madrid, Spain., Felip E; Medical Oncology Department, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain.

المصدر: Clinical drug investigation [Clin Drug Investig] 2024 Aug; Vol. 44 (8), pp. 553-576. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Lactams* , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Anaplastic Lymphoma Kinase*/antagonists & inhibitors , Anaplastic Lymphoma Kinase*/genetics , Aminopyridines*/adverse effects , Pyrazoles*/adverse effects , Pyrazoles*/therapeutic use , Lactams, Macrocyclic*, Humans ; Protein Kinase Inhibitors/adverse effects ; Protein Kinase Inhibitors/therapeutic use ; Consensus ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use

المؤلفون: Wilson I; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Qiu M; Sydpath, St Vincent's Hospital, Sydney, Australia.; St Vincent's Clinical School, University of New South Wales, Sydney, Australia., Itchins M; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.; Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia., Wang B; Sydpath, St Vincent's Hospital, Sydney, Australia., Huang ML; Sydpath, St Vincent's Hospital, Sydney, Australia.; Kinghorn Centre for Cancer Genomics Medicine, Garvan Institute of Medical Research, Sydney, Australia., Grimison P; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

المصدر: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2024 Aug; Vol. 7 (8), pp. e2164.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print Cited Medium: Internet ISSN: 2573-8348 (Electronic) Linking ISSN: 25738348 NLM ISO Abbreviation: Cancer Rep (Hoboken) Subsets: MEDLINE

مواضيع طبية MeSH: Oncogene Proteins, Fusion*/genetics , Drug Resistance, Neoplasm*/genetics , Protein Kinase Inhibitors*/therapeutic use , Anaplastic Lymphoma Kinase*/genetics , Anaplastic Lymphoma Kinase*/antagonists & inhibitors , Sarcoma*/genetics , Sarcoma*/drug therapy , Sarcoma*/pathology , Lactams* , Mutation* , Lactams, Macrocyclic*/therapeutic use, Humans ; Male ; Middle Aged ; Pyrazoles/therapeutic use ; Fatal Outcome ; Aminopyridines/therapeutic use ; Carbazoles/therapeutic use ; Carbazoles/administration & dosage ; Piperidines/therapeutic use ; Tyrosine Kinase Inhibitors