المؤلفون: Han S; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA., Yao J; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA., Yamazaki H; Section of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto 606-8303, Japan.; Center for Innovative Research for Communities and Clinical Excellence (CiRC2LE), Fukushima Medical University, Fukushima 960-1295, Japan., Streicher SA; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI 96813, USA., Rao J; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Nianogo RA; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA., Zhang Z; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA., Huang BZ; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

المصدر: Nutrients [Nutrients] 2024 Mar 12; Vol. 16 (6). Date of Electronic Publication: 2024 Mar 12.

نوع المنشور: Meta-Analysis; Journal Article

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Lactase-Phlorizin Hydrolase*/genetics , Colorectal Neoplasms*/epidemiology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/prevention & control, Humans ; Mendelian Randomization Analysis

المؤلفون: Marten LM; Department of Biochemistry, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany; Department of Pediatrics, University Medical Center Eppendorf, Martinistr. 52, 20251 Hamburg, Germany., Wanes D; Department of Biochemistry, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany., Stellbrinck T; Department of Biochemistry, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany., Santer R; Department of Pediatrics, University Medical Center Eppendorf, Martinistr. 52, 20251 Hamburg, Germany., Naim HY; Department of Biochemistry, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany. Electronic address: Hassan.Naim@tiho-hannover.de.

المصدر: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Apr 01; Vol. 1868 (4), pp. 166338. Date of Electronic Publication: 2022 Jan 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

مواضيع طبية MeSH: Carbohydrate Metabolism, Inborn Errors/*pathology , Lactase/*deficiency , Lactase-Phlorizin Hydrolase/*genetics, Animals ; COS Cells ; Carbohydrate Metabolism, Inborn Errors/genetics ; Chlorocebus aethiops ; Humans ; Lactase/genetics ; Lactase-Phlorizin Hydrolase/chemistry ; Lactase-Phlorizin Hydrolase/metabolism ; Mutagenesis, Site-Directed ; Mutation, Missense ; Protein Folding ; Protein Transport

SCR Disease Name: Lactase Deficiency, Congenital

المؤلفون: Wanes D; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany. dalanda.wanes@tiho-hannover.de.; Laboratory of Functional Physiology and Valorization of Bioresources⁻Higher Institute of Biotechnology of Béja, University of Jendouba, Jendouba 8189, Tunisia. dalanda.wanes@tiho-hannover.de., Husein DM; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany. diab.husein@tiho-hannover.de., Naim HY; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany. Hassan.Naim@tiho-hannover.de.

المصدر: Nutrients [Nutrients] 2019 Feb 22; Vol. 11 (2). Date of Electronic Publication: 2019 Feb 22.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Carbohydrate Metabolism, Inborn Errors/*diagnosis , Lactase/*deficiency , Lactase-Phlorizin Hydrolase/*deficiency , Lactase-Phlorizin Hydrolase/*genetics, Carbohydrate Metabolism, Inborn Errors/genetics ; Carbohydrate Metabolism, Inborn Errors/pathology ; Genotype ; Humans ; Lactase/genetics ; Lactase-Phlorizin Hydrolase/metabolism ; Mutation

SCR Disease Name: Lactase Deficiency, Congenital

المؤلفون: Amiri M; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany. mahdi.amiri@tiho-hannover.de., Diekmann L; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany. lena.diekmann@tiho-hannover.de., von Köckritz-Blickwede M; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany. maren.von.koeckritz-blickwede@tiho-hannover.de.; The Research Center for Emerging Infections and Zoonosis (RIZ), University of Veterinary Medicine Hannover, Hannover, Germany. maren.von.koeckritz-blickwede@tiho-hannover.de., Naim HY; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany. hassan.naim@tiho-hannover.de.

المصدر: Nutrients [Nutrients] 2015 Aug 28; Vol. 7 (9), pp. 7209-30. Date of Electronic Publication: 2015 Aug 28.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Lactase/*deficiency , Lactase-Phlorizin Hydrolase/*metabolism , Lactose Intolerance/*epidemiology , Neoplasms/*epidemiology, Dairy Products/adverse effects ; Genetic Predisposition to Disease ; Humans ; Incidence ; Lactase/classification ; Lactase/genetics ; Lactase-Phlorizin Hydrolase/genetics ; Lactose/metabolism ; Lactose Intolerance/classification ; Lactose Intolerance/diagnosis ; Lactose Intolerance/enzymology ; Lactose Intolerance/genetics ; Mutation ; Neoplasms/diagnosis ; Phenotype ; Prevalence ; Protective Factors ; Protein Conformation ; Risk Assessment ; Risk Factors ; Structure-Activity Relationship

SCR Disease Name: Lactose Intolerance, Adult Type

المؤلفون: Diekmann L; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Buenteweg 17, D-30559, Hannover, Germany. lena.diekmann@tiho.hannover.de., Pfeiffer K; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Buenteweg 17, D-30559, Hannover, Germany. katrin.pfeiffer@tiho.hannover.de., Naim HY; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Buenteweg 17, D-30559, Hannover, Germany. hassan.naim@tiho.hannover.de.

المصدر: BMC gastroenterology [BMC Gastroenterol] 2015 Mar 21; Vol. 15, pp. 36. Date of Electronic Publication: 2015 Mar 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Heterozygote* , Mutation*, Carbohydrate Metabolism, Inborn Errors/*genetics , Lactase/*deficiency , Lactase-Phlorizin Hydrolase/*genetics , Lactose Intolerance/*genetics, Animals ; COS Cells ; Carbohydrate Metabolism, Inborn Errors/enzymology ; Chlorocebus aethiops ; Genetic Markers ; Humans ; Lactase/genetics ; Lactase-Phlorizin Hydrolase/biosynthesis ; Lactase-Phlorizin Hydrolase/chemistry ; Lactase-Phlorizin Hydrolase/physiology ; Lactose Intolerance/enzymology

SCR Disease Name: Lactase Deficiency, Congenital

المؤلفون: Anguita-Ruiz A; Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology 'José Mataix', Center of Biomedical Research, University of Granada, Avda. del Conocimiento s/n. Armilla, 18016 Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, 18014 Granada, Spain.; CIBEROBN (Physiopathology of Obesity and Nutrition Network CB12/03/30038), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain., Aguilera CM; Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology 'José Mataix', Center of Biomedical Research, University of Granada, Avda. del Conocimiento s/n. Armilla, 18016 Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, 18014 Granada, Spain.; CIBEROBN (Physiopathology of Obesity and Nutrition Network CB12/03/30038), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain., Gil Á; Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology 'José Mataix', Center of Biomedical Research, University of Granada, Avda. del Conocimiento s/n. Armilla, 18016 Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, 18014 Granada, Spain.; CIBEROBN (Physiopathology of Obesity and Nutrition Network CB12/03/30038), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.

المصدر: Nutrients [Nutrients] 2020 Sep 03; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Genotype* , Phenotype*, Lactose Intolerance/*genetics, Adult ; Animals ; Epigenomics ; Ethnicity ; Evolution, Molecular ; Humans ; Lactase/genetics ; Lactase-Phlorizin Hydrolase/genetics ; Lactose ; Lactose Intolerance/classification ; Milk ; Polymorphism, Single Nucleotide

المؤلفون: de Laffolie J; Department of Paediatrics, Justus-Liebig-University Giessen, Giessen, Germany., Sheridan D; Department of Pathology, Justus-Liebig-University Giessen, Giessen, Germany., Reinshagen K; Department of Pediatric Surgery, UKE: University Hospital Eppendorf, Altona Children's Hospital, Hamburg, Germany., Wessel L; Department of Pediatric Surgery, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany., Zimmermann C; Department of Paediatrics, Justus-Liebig-University Giessen, Giessen, Germany., Stricker S; Department of Paediatrics, Justus-Liebig-University Giessen, Giessen, Germany., Lerch MM; Department of Internal Medicine A, Ernst-Moritz-Arndt University, Greifswald, Germany., Weigel M; Institute of Medical Microbiology, Justus-Liebig-University Giessen, Giessen, Germany.; German Centre for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Justus Liebig University Giessen, Giessen, Germany., Hain T; Institute of Medical Microbiology, Justus-Liebig-University Giessen, Giessen, Germany.; German Centre for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Justus Liebig University Giessen, Giessen, Germany., Domann E; Institute of Medical Microbiology, Justus-Liebig-University Giessen, Giessen, Germany.; German Centre for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Justus Liebig University Giessen, Giessen, Germany., Rudloff S; Department of Paediatrics, Justus-Liebig-University Giessen, Giessen, Germany., Nichols BL; Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA., Naim HY; Department of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany., Zimmer KP; Department of Paediatrics, Justus-Liebig-University Giessen, Giessen, Germany.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Mar; Vol. 34 (3), pp. 3983-3995. Date of Electronic Publication: 2020 Jan 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Intestine, Large/*enzymology , Short Bowel Syndrome/*enzymology, Aminopeptidases/metabolism ; Blotting, Western ; Disaccharidases/metabolism ; Female ; Humans ; Lactase-Phlorizin Hydrolase/metabolism ; Lactobacillus/physiology ; Male ; Microscopy, Immunoelectron ; Peptide Hydrolases/metabolism ; Proteobacteria/physiology ; Sucrase-Isomaltase Complex/metabolism

المؤلفون: Behrendt M; From the Department of Physiological Chemistry, University of Veterinary Medicine Hannover, D-30559 Hannover, Germany and., Polaina J; the Instituto de Agroquímica y Tecnología de Alimentos, Consejo Superior de Investigaciones Científicas, Apartado de Correos 73, Burjassot, E46100 Valencia, Spain., Naim HY; From the Department of Physiological Chemistry, University of Veterinary Medicine Hannover, D-30559 Hannover, Germany and. Electronic address: Hassan.Naim@tiho-hannover.de.

المصدر: The Journal of biological chemistry [J Biol Chem] 2010 Feb 05; Vol. 285 (6), pp. 4143-4152. Date of Electronic Publication: 2009 Dec 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Protein Folding*, Intestinal Mucosa/*enzymology , Lactase-Phlorizin Hydrolase/*chemistry , Lactase-Phlorizin Hydrolase/*metabolism, Animals ; COS Cells ; Catalytic Domain/genetics ; Cell Line ; Chlorocebus aethiops ; Electrophoresis, Polyacrylamide Gel ; Endoplasmic Reticulum/enzymology ; Golgi Apparatus/enzymology ; Humans ; Immunoprecipitation ; Lactase-Phlorizin Hydrolase/genetics ; Lactose/metabolism ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Microscopy, Confocal ; Models, Molecular ; Mutation ; Phlorhizin/metabolism ; Protein Multimerization ; Protein Structure, Tertiary ; Protein Transport ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Structure-Activity Relationship ; Transfection

المؤلفون: Sibley E; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition Stanford University School of Medicine, 300 Pasteur Drive, G310, Stanford, CA 94305, USA. eric.sibley@stanford.edu, Ahn JK

المصدر: Transactions of the American Clinical and Climatological Association [Trans Am Clin Climatol Assoc] 2011; Vol. 122, pp. 155-65.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Clinical And Climatological Association Country of Publication: United States NLM ID: 7507559 Publication Model: Print Cited Medium: Internet ISSN: 0065-7778 (Print) Linking ISSN: 00657778 NLM ISO Abbreviation: Trans Am Clin Climatol Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide* , Promoter Regions, Genetic*, Black People/*genetics , Carbohydrate Metabolism, Inborn Errors/*genetics , Intestinal Mucosa/*enzymology , Lactase/*genetics , Lactase-Phlorizin Hydrolase/*genetics, Awards and Prizes ; Caco-2 Cells ; Carbohydrate Metabolism, Inborn Errors/enzymology ; Carbohydrate Metabolism, Inborn Errors/ethnology ; Gene Expression Regulation, Enzymologic ; Genetic Predisposition to Disease ; Humans ; Hydrolysis ; Lactase/metabolism ; Lactase-Phlorizin Hydrolase/metabolism ; Lactose/metabolism ; Phenotype ; Transfection

المؤلفون: Babu J; Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India., Kumar S, Babu P, Prasad JH, Ghoshal UC

المصدر: The American journal of clinical nutrition [Am J Clin Nutr] 2010 Jan; Vol. 91 (1), pp. 140-6. Date of Electronic Publication: 2009 Nov 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0376027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3207 (Electronic) Linking ISSN: 00029165 NLM ISO Abbreviation: Am J Clin Nutr Subsets: MEDLINE

مواضيع طبية MeSH: Lactase-Phlorizin Hydrolase/*genetics , Lactose/*metabolism , Lactose Intolerance/*epidemiology , Lactose Intolerance/*genetics , Lactose Tolerance Test/*methods, Blood Glucose/metabolism ; Breath Tests ; DNA/blood ; DNA/genetics ; DNA Primers ; Fasting ; Genotype ; Geography ; Humans ; Hydrogen/analysis ; India/epidemiology ; Intestine, Small/enzymology ; Irritable Bowel Syndrome/diagnosis ; Lactase/metabolism ; Lactase-Phlorizin Hydrolase/deficiency ; Polymorphism, Restriction Fragment Length ; Sensitivity and Specificity