المؤلفون: Younes Belkouchi, Laetitia Nebot-Bral, Littisha Lawrance, Michele Kind, Clémence David, Samy Ammari, Paul-Henry Cournède, Hugues Talbot, Perrine Vuagnat, Cristina Smolenschi, Patricia L. Kannouche, Nathalie Chaput, Nathalie Lassau, Antoine Hollebecque

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: mismatch repair (MMR) deficiency, immunotherapy, CT scan, tumor volume, biomarker, anti-PD1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.982790/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/fae99fd4b90a457bb087c481b50e2a46

المؤلفون: Jean-Yves Scoazec, Antoine Hollebecque, Aurélien Marabelle, Alexandra Leary, Lydie Cassard, Nathalie Chaput, Cristina Smolenschi, Perrine Vuagnat, Jean-Mehdi Jouniaux, Laetitia Nebot-Bral, Andrey A Yurchenko, Louise de Forceville, Mathieu Danjou, Reginaldo C A Rosa, Caroline Pouvelle, Said Aoufouchi, Emeline Colomba, Sergey Nikolaev, Patricia Kannouche

المصدر: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://jitc.bmj.com/content/10/7/e005059.full; https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/e34026e4687a48cba574cb8fd575cd1c

المؤلفون: Clélia Coutzac, Jean-Mehdi Jouniaux, Angelo Paci, Julien Schmidt, Domenico Mallardo, Atmane Seck, Vahe Asvatourian, Lydie Cassard, Patrick Saulnier, Ludovic Lacroix, Paul-Louis Woerther, Aurore Vozy, Marie Naigeon, Laetitia Nebot-Bral, Mélanie Desbois, Ester Simeone, Christine Mateus, Lisa Boselli, Jonathan Grivel, Emilie Soularue, Patricia Lepage, Franck Carbonnel, Paolo Antonio Ascierto, Caroline Robert, Nathalie Chaput

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1117fcdf2fd44e30b8bbaa1e829d3ecf

المؤلفون: Edouard Auclin, Perrine Vuagnat, Cristina Smolenschi, Julien Taieb, Jorge Adeva, Laetitia Nebot-Bral, Marta Garcia de Herreros, Rosario Vidal Tocino, Federico Longo-Muñoz, Yola El Dakdouki, Patricia Martín-Romano, Lydia Gaba, Tamara Saurí, Helena Oliveres, Eduardo Castañón, Rocio Garcia-Carbonero, Benjamin Besse, Christophe Massard, Laura Mezquita, Antoine Hollebecque

المصدر: Cancers, Vol 13, Iss 15, p 3776 (2021)

مصطلحات موضوعية: LIPI, dNLR, LDH, MSI-H, dMMR, immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6694/13/15/3776; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/5914bac3321d482f8b15a43fb558ad2f

المؤلفون: Patricia Martin-Romano, H. Oliveres, Cristina Smolenschi, Lydia Gaba, P. Vuagnat, Jorge Adeva, Eduardo Castanon, Yola El Dakdouki, Laetitia Nebot-Bral, Rocio Garcia-Carbonero, Benjamin Besse, Marta Garcia de Herreros, Federico Longo-Muñoz, Tamara Sauri, Rosario Vidal Tocino, Edouard Auclin, Julien Taieb, Antoine Hollebecque, Laura Mezquita, Christophe Massard

المصدر: Cancers, Vol 13, Iss 3776, p 3776 (2021)
Cancers
Volume 13
Issue 15

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, LDH, medicine.medical_treatment, LIPI, Gastroenterology, Article, immune checkpoint inhibitors, 03 medical and health sciences, 0302 clinical medicine, Immune system, Refractory, Internal medicine, medicine, Clinical endpoint, dMMR, RC254-282, Predictive marker, Lung, Performance status, business.industry, MSI-H, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Retrospective cohort study, Immunotherapy, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, dNLR, immunotherapy, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d8359793954215378670b8aff62b88
https://www.mdpi.com/2072-6694/13/15/3776

المؤلفون: Laetitia Nebot-Bral, Antoine Hollebecque, Andrey A Yurchenko, Louise de Forceville, Mathieu Danjou, Jean-Mehdi Jouniaux, Reginaldo C A Rosa, Caroline Pouvelle, Said Aoufouchi, Perrine Vuagnat, Cristina Smolenschi, Emeline Colomba, Alexandra Leary, Aurelien Marabelle, Jean-Yves Scoazec, Lydie Cassard, Sergey Nikolaev, Nathalie Chaput, Patricia Kannouche

المصدر: Journal for ImmunoTherapy of Cancer. 10:e005059

مصطلحات موضوعية: Pharmacology, Cancer Research, Brain Neoplasms, Neutrophils, Immunology, Mice, Oncology, Neoplastic Syndromes, Hereditary, Tin, Tumor Microenvironment, Animals, Humans, Molecular Medicine, Immunology and Allergy, Microsatellite Instability, Colorectal Neoplasms, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c325fa6f6c3c343b15f7c8a11ddc42f
https://doi.org/10.1136/jitc-2022-005059

المؤلفون: Julien Schmidt, Ludovic Lacroix, Atmane Seck, Aurore Vozy, Patrick Saulnier, Jonathan Grivel, Nathalie Chaput, Jean Mehdi Jouniaux, Ester Simeone, Franck Carbonnel, Paolo A. Ascierto, Laetitia Nebot-Bral, M. Naigeon, Domenico Mallardo, L. Boselli, Paul Louis Woerther, Caroline Robert, Lydie Cassard, Patricia Lepage, Angelo Paci, Clélia Coutzac, Mélanie Desbois, Christine Mateus, V. Asvatourian, Emilie Soularue

المساهمون: Micalis Institute, INRA, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France, Laboratoire d’Immunomonitoring en Oncologie (LIO), Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse (AMMICa), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Faculté de Médecine Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)-Université Paris-Saclay, Institut Gustave Roussy (IGR), Vectorologie et thérapeutiques anti-cancéreuses [Villejuif] (UMR 8203), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, Fondazione IRCCS Istituto Nazionale Tumori - National Cancer Institute [Milan], Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, IRCCS Istituto Nazionale dei Tumori [Milano], AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Instituto Nazionale Tumori-Fondazione 'G. Pascale', Direction de la recherche [Gustave Roussy], Fondation Gustave Roussy Direction Générale de l’offre de Soins, DGOS: TRANSLA 12-174 Institut National de la Santé et de la Recherche Médicale, Inserm Centre National de la Recherche Scientifique, CNRS: INCa-DGOS-INSERM_12551, ANR-10IBHU-0001 Fondation Gustave Roussy Institut National Du Cancer, INCa: 2012-1-RT-14-IGR-01 Fondation pour la Recherche Médicale, FRM AstraZeneca Sanofi GlaxoSmithKline Australia, GSK, The authors thank Dr. Patrick Gonin from the PlatForm for Preclinical Evaluation (PFEP). Fundings: This study was funded by Gustave Roussy Cancer Campus, Fondation Gustave Roussy, the Institut national de la santé et de la recherche médicale (INSERM), the Centre national de la recherche scientifique (CNRS), SIRIC SOCRATE (INCa DGOS INSERM 6043), SIRIC SOCRATE 2.0 (INCa-DGOS-INSERM_12551), MMO program: ANR-10IBHU-0001), Direction General de l’Offre de Soins (DGOS, TRANSLA 12-174), Institut National du Cancer (INCa, 2012-062 N_ Canceropole: 2012-1-RT-14-IGR-01). Dr. Clélia Coutzac was supported by fellowships from Fondation pour la Recherche Medicale (FRM) from 2015 to 2016., N.C. reports research grants from Cytune Pharma, GSK, Sanofi, has participated in advisory boards for AstraZeneca and has been a speaker for Sanofi and AstraZeneca. C.R. has participated in advisory boards for Roche, GSK, Merck, Novartis, Amgen, BMS and Novartis. Franck Carbonnel received boards or lecture fees from enterome, Amgen, Astra, MSD, BMS, Janssen, Pfizer, Abbvie, Mayoly Spindler, Takeda, Pileje, Roche. E. Soularue has participated in advisory board for Novartis. L.L. has participated in advisory boards for Roche, Astrazeneca, BMS, Genomic Health, Illumina, Qiagen, Novartis Thermofisher and has been a speaker for Amgen, AstraZeneca, Dyn, Vela diagnostics, Luye Pharma, and Roche. P.A.A. has/had a consultant/advisory role for Bristol Myers-Squibb, Roche-Genentech, Merck Sharp & Dohme, Array, Novartis, Amgen, Merck Serono, Pierre Fabre, Incyte, NewLink Genetics, Genmab, Medimmune, AstraZeneca, Syndax, SunPharma, Sanofi, Idera. He also received Research funds from Bristol Myers-Squibb, Roche-Genentech, Array. The other authors have no conflicts of interest to declare., ANR-10-IBHU-0001,MMO (IHU-CANCER),Institut de Médecine Personnalisée du Cancer(2010)

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-16079-x⟩
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], T-Lymphocytes, medicine.medical_treatment, General Physics and Astronomy, Pharmacology, Gut flora, T-Lymphocytes, Regulatory, Immune tolerance, Tumour biomarkers, Mice, 0302 clinical medicine, Neoplasms, RNA, Ribosomal, 16S, CTLA-4 Antigen, lcsh:Science, Cancer, Mice, Inbred BALB C, Multidisciplinary, biology, Chemistry, hemic and immune systems, 3. Good health, Butyrates, 030220 oncology & carcinogenesis, B7-1 Antigen, Science, Immunology, [SDV.CAN]Life Sciences [q-bio]/Cancer, chemical and pharmacologic phenomena, Butyrate, digestive system, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, Biomarkers, Tumor, medicine, Animals, Humans, CD86, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Dendritic Cells, General Chemistry, Immunotherapy, Fatty Acids, Volatile, biology.organism_classification, Ipilimumab, Gastrointestinal Microbiome, 030104 developmental biology, CTLA-4, lcsh:Q, B7-2 Antigen, Propionates, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Biomarkers, CD80

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cce94443436fc757640bcdfcf82411
https://doi.org/10.1038/s41467-020-16079-x

المؤلفون: Antoine Hollebecque, P.L. Kannouche, Aurélien Marabelle, Laetitia Nebot-Bral, Cristina Smolenschi, Said Aoufouchi, Sergey Nikolaev, L. De Forceville, M. Danjou, Nathalie Chaput, P. Vuagnat, J-Y. Scoazec, Andrey A. Yurchenko

المصدر: Annals of Oncology. 32:S1226

مصطلحات موضوعية: Oncology, business.industry, Anti pd 1, Cancer research, Medicine, DNA mismatch repair, Hematology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b35a8a10b89eb12d1a55b22ec0bf02bd
https://doi.org/10.1016/j.annonc.2021.08.255

المؤلفون: Laetitia Nebot-Bral, Patricia Kannouche, Clelia Coutzac, Nathalie Chaput

المساهمون: Stabilité Génétique et Oncogenèse (UMR 8200), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d’Immunomonitoring en Oncologie (LIO), Analyse moléculaire, modélisation et imagerie de la maladie cancéreuse (AMMICa), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Kannouche, patricia

المصدر: Bulletin du Cancer
Bulletin du Cancer, John Libbey Eurotext, 2019, 106 (2), pp.105-113. ⟨10.1016/j.bulcan.2018.08.007⟩
Bulletin du Cancer, 2019, 106 (2), pp.105-113. ⟨10.1016/j.bulcan.2018.08.007⟩

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Context (language use), [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.GEN] Life Sciences [q-bio]/Genetics, DNA Mismatch Repair, B7-H1 Antigen, Mutation Accumulation, 03 medical and health sciences, 0302 clinical medicine, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, Antigen, Neoplasms, Tumor Microenvironment, medicine, Humans, CTLA-4 Antigen, Radiology, Nuclear Medicine and imaging, ComputingMilieux_MISCELLANEOUS, Tumor microenvironment, [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, business.industry, Microsatellite instability, Hematology, General Medicine, Immunotherapy, Prognosis, medicine.disease, Immune checkpoint, 3. Good health, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Microsatellite Instability, DNA mismatch repair, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bdcfae60b44698cd5fa1a59ca66c9d
https://hal.archives-ouvertes.fr/hal-02425478

المؤلفون: Patricia Kannouche, Nathalie Chaput, Said Aoufouchi, Laetitia Nebot-Bral, Stéphane Champiat, David Brandao, David Malka, Emmanuelle Despras, Olivier Caron, Aurélien Marabelle, Loic Verlingue, Alexandra Leary, Yolla El-Dakdouki, Etienne Rouleau

المصدر: European journal of cancer (Oxford, England : 1990). 84

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, DNA Mutational Analysis, Pembrolizumab, Biology, DNA Mismatch Repair, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigens, Neoplasm, Predictive Value of Tests, Neoplasms, medicine, Biomarkers, Tumor, Tumor Microenvironment, Humans, Genetic Predisposition to Disease, Molecular Targeted Therapy, Precision Medicine, Poly-ADP-Ribose Binding Proteins, DNA Polymerase III, Tumor microenvironment, Microsatellite instability, Immunotherapy, DNA Polymerase II, Precision medicine, medicine.disease, 030104 developmental biology, Phenotype, Oncology, Tumor Escape, 030220 oncology & carcinogenesis, Immunology, Mutation, Cancer research, DNA mismatch repair, Microsatellite Instability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f69dfc275cd33e1e5773525884cb272
https://pubmed.ncbi.nlm.nih.gov/28846956