المؤلفون: Sudre, L, Cheung, F, Kevorkian, L, Young, DA, Darrah, C, Donell, ST, Shepstone, L, Porter, S, Brockbank, S, Edwards, DR, Parker, AE, Clark, IM, Boubriak, OA, Urban, JPG, Cui, Z, Tew, SR, Li, Y, Tweats, LM, Hawkins, RE, Hardingham, TE, Green, D, Partridge, KA, Leveque, I, Mann, S, Oreffo, ROC, Ball, SG, Kielty, CM, Qin, M, Tai, G, Polak, JM, Bishop, AE, Stolzing, A, Scutt, A, Screen, HRC, Shelton, JC, Bader, DL, Lee, DA, Hall, A, Hayes, A, Brown, L, Tubo, R, Caterson, B, Blain, EJ, Gilbert, SJ, Duance, VC, Davies, L, Blain, E, Duance, V, Shengda, Z, Wu, M-H, Xu, X, Heywood, HK, Sims, T, Miot, S, Martin, I, Roughley, PJ, Soranzo, C, Pavesio, A, Hollander, AP, Yang, X, Webb, D, Blaker, J, Maquet, V, Boccaccini, AR, Cooper, C, Eves, P, Beck, AJ, Shard, AG, Gawkrodger, DJ, Mac Neil, S, Rajpar, MH, Kadler, KE, Thornton, DJ, Briggs, MD, Boot-Handford, RP, Ellis, MJ, Tai, C-C, Perera, S, Chaudhuri, JB, Callender, P, Mason, DJ, Colley, H, Mc Arthur, S, Mirmalek-Sani, SH, Roach, HI, Hanley, NA, Wilson, DI, MacIntosh, AC, Crawford, A, Hatton, PV, Wallis, G, Shah, R, Knowles, JC, Hunt, NP, Lewis, MP, Rippon, HJ, Ali, BE, De Bank, PA, Kellam, B, Shakesheff, KM, Comerford, EJ, Tarlton, JF, Wales, A, Bailey, AJ, Innes, JF, Olivier, V, Xie, Y, Descamps, M, Hivart, P, Lu, J, Hardouin, P, Anderson, V, Spiller, DG, Vaughan-Thomas, A, Eissa, SZS, Faram, T, Birch, HL, Zeugolis, D, Paul, G, Attenburrow, G, Bhadal, N, Whawell, SA, Worrall, LK, Rose, FRAJ, Bradshaw, TD, Stevens, MFG, Chuo, CB, Wiseman, MA, Phillips, JB, Brown, RA, Harrison, CA, Gossiel, F, Bullock, AJ, Blumsohn, A, Li, Z, Derham, B, Gaissmaier, C, Fritz, J, Krackhardt, T, Flesch, I, Aicher, WK, Ashammakhi, N, Liu, K-K, Yang, Y, Ahearne, M, Then, K, El Haj, A, Cheung, I, Wright, TC, Kostyuk, O, Baria, KE, Chowdhury, TT, Sharma, AM, Bomzon, Z, Kimmel, E, Knight, MM, Dickinson, S, Pittarello, L, Fish, RS, Ralphs, JR, Farjanel, J, Sève, S, Borel, A, Sommer, P, Hulmes, DJS, Whiting, CV, Dalton, SJ, Mitchell, DC, Kafienah, W, Mistry, S, Hollander, A, Cartmell, S, Magnay, J, Dobson, J, Appleby, RN, Salter, DM, Scutt, N, Rolf, CG, Barry, JJA, Nazhat, SN, Scotchford, CA, Howdle, SM, Roberts, S, Gargiulo, B, Evans, EH, Menage, J, Johnson, WEB, Eisenstein, S, Richardson, JB, Stenfeldt, C, Avery, NC, Tidswell, H, Crabtree, J, Frazer, A, Fraser, S, Wong, M, Beckett, K, Grobbelaar, A, Mudera, V, Bax, DV, Cain, SA, Humphries, MJ, Lomas, A, Oldershaw, R, Murdoch, A, Brennan, K, Redman, S, Haughton, L, Dowthwaite, G, Williams, A, Archer, CW, Esfandiari, E, Stokes, CR, Cox, TM, Evans, MJ, Bailey, M, Hayman, AR, Day, MJ, Williams, R, Evans, D, Adesida, A, Millwards-Sadler, J, Salter, D, Smith, R, Korda, M, Porter, R, Kalia, P, Wiseman, M, Blunn, G, Goodship, A, McClumpha, A, Horrocks, M, Pabbruwe, MB, Du, X, Stewart, K, Suciati, T, Lakey, RL, Pennington, CJ, Cawston, TE, Palmer, L, Tasman, C, Clare, M, Gidley, J, Sandy, J, Mansell, J, Ellis, T, Burger, F, Lauder, R, Khan, I, Smith, M

المصدر: University of Manchester-PURE

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c8c4b4d45b13bf24949445c243dcea8a
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المؤلفون: Barter MJ; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK., Hui W, Lakey RL, Catterall JB, Cawston TE, Young DA

المصدر: Annals of the rheumatic diseases [Ann Rheum Dis] 2010 Dec; Vol. 69 (12), pp. 2189-98. Date of Electronic Publication: 2010 Aug 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE

مواضيع طبية MeSH: Cartilage, Articular/*drug effects , Collagen/*metabolism , Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology , Matrix Metalloproteinases/*physiology , Nasal Cartilages/*drug effects, Animals ; Cartilage, Articular/metabolism ; Cattle ; Cells, Cultured ; Collagenases/biosynthesis ; Down-Regulation/drug effects ; Gelatinases/biosynthesis ; Gene Expression Regulation, Enzymologic/drug effects ; Humans ; Interleukin-1alpha/pharmacology ; Lovastatin/analogs & derivatives ; Lovastatin/pharmacology ; Matrix Metalloproteinases/genetics ; Mevalonic Acid/pharmacology ; Nasal Cartilages/metabolism ; Oncostatin M/pharmacology ; Signal Transduction/drug effects ; Simvastatin/antagonists & inhibitors ; Simvastatin/pharmacology ; Terpenes/metabolism ; Tissue Culture Techniques

المؤلفون: Rankin KS; Musculoskeletal Research Group, University of Newcastle upon Tyne, Medical School, Newcastle upon Tyne, United Kingdom. ksrankin@yahoo.co.uk, Lakey RL, Gerrand CH, Sprowson AP, McCaskie AW, Birch MA

المصدر: The Journal of rheumatology [J Rheumatol] 2010 Feb; Vol. 37 (2), pp. 426-31. Date of Electronic Publication: 2009 Dec 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Journal Of Rheumatology Publishing Co Country of Publication: Canada NLM ID: 7501984 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0315-162X (Print) Linking ISSN: 0315162X NLM ISO Abbreviation: J Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Culture Techniques*, Cartilage, Articular/*metabolism , Chondrocytes/*metabolism , Osteoarthritis/*metabolism, Analysis of Variance ; Cartilage, Articular/cytology ; Cell Shape ; Cells, Cultured ; Chondrocytes/cytology ; Collagen Type II/genetics ; Collagen Type II/metabolism ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Matrix Metalloproteinase 1/genetics ; Matrix Metalloproteinase 1/metabolism ; Osteoarthritis/genetics ; Proteoglycans/genetics ; Proteoglycans/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SOX9 Transcription Factor/genetics ; SOX9 Transcription Factor/metabolism

المؤلفون: Cawston TE; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK., Lakey RL, Rowan AD

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2010; Vol. 622, pp. 245-55.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Assays/*methods , Matrix Metalloproteinases/*metabolism, Animals ; Cattle ; Enzyme Activation/drug effects ; Enzyme Precursors/metabolism ; Phenylmercuric Acetate/analogs & derivatives ; Phenylmercuric Acetate/pharmacology ; Staining and Labeling ; Substrate Specificity/drug effects ; Trypsin/pharmacology

المؤلفون: Lakey RL; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK., Cawston TE

المصدر: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2009 Oct; Vol. 48 (10), pp. 1208-12. Date of Electronic Publication: 2009 Aug 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

مواضيع طبية MeSH: Antirheumatic Agents/*pharmacology , Collagen/*metabolism , Hyaline Cartilage/*drug effects , Proteoglycans/*metabolism , Sulfasalazine/*pharmacology, Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Cartilage, Articular/drug effects ; Cartilage, Articular/metabolism ; Cattle ; Cells, Cultured ; Culture Media, Conditioned ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Drug Evaluation, Preclinical/methods ; Gene Expression Regulation, Enzymologic/drug effects ; Humans ; Hyaline Cartilage/metabolism ; Interleukin-1alpha/antagonists & inhibitors ; Interleukin-1alpha/pharmacology ; Metalloproteases/biosynthesis ; Nasal Cartilages/drug effects ; Nasal Cartilages/metabolism ; Oncostatin M/antagonists & inhibitors ; Oncostatin M/pharmacology ; Osteoarthritis, Knee/metabolism

المؤلفون: Lakey RL; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK., Morgan TG, Rowan AD, Isaacs JD, Cawston TE, Hilkens CM

المصدر: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2009 May; Vol. 48 (5), pp. 502-7. Date of Electronic Publication: 2009 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid/*immunology , Cartilage, Articular/*immunology , Dendritic Cells/*immunology, Antibodies, Monoclonal/pharmacology ; CD40 Ligand/metabolism ; Cartilage, Articular/drug effects ; Cells, Cultured ; Coculture Techniques ; Collagen/metabolism ; Collagenases/metabolism ; Humans ; Immunoglobulin gamma-Chains/pharmacology ; Infliximab ; Receptors, Tumor Necrosis Factor ; Recombinant Fusion Proteins/pharmacology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/biosynthesis ; Tumor Necrosis Factor-alpha/physiology ; Up-Regulation

المؤلفون: Litherland GJ; Cell Signalling, Injury, and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Dixon C, Lakey RL, Robson T, Jones D, Young DA, Cawston TE, Rowan AD

المصدر: The Journal of biological chemistry [J Biol Chem] 2008 May 23; Vol. 283 (21), pp. 14221-9. Date of Electronic Publication: 2008 Mar 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Enzymologic* , Signal Transduction*/drug effects, Cartilage/*enzymology , Collagenases/*metabolism , Phosphatidylinositol 3-Kinases/*metabolism , Proto-Oncogene Proteins c-akt/*metabolism, Animals ; Cartilage/drug effects ; Cells, Cultured ; Chondrocytes/drug effects ; Chondrocytes/enzymology ; Humans ; Interleukin-1/pharmacology ; Interleukin-6/pharmacology ; Isoenzymes/metabolism ; Mice ; Oncostatin M/pharmacology ; Phosphorylation/drug effects ; Protein Kinase Inhibitors/pharmacology ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Pyruvate Dehydrogenase Acetyl-Transferring Kinase