المؤلفون: Rodríguez Vásquez, Sofía

مصطلحات موضوعية: Progeria -- genetics, Progeria -- pathology, Lamin Type A -- genetics, Lamin Type A -- metabolism, Gene Expression, Cell Aging, Aging, Premature -- genetics, Alternative Splicing, Protein Isoforms -- genetics

Degree: Diss. (sammanfattning) Stockholm : Karolinska Institutet, 2014

المؤلفون: Schmidt, Eva

مصطلحات موضوعية: Progeria -- genetics, Progeria -- metabolism, Disease Models, Animal, Mice, Gene Expression, Brain -- metabolism, Bone and Bones -- metabolism, Tooth -- metabolism, Lamin Type A -- genetics, Lamin Type A -- metabolism, Mutation, Nuclear Proteins -- genetics, Nuclear Proteins -- metabolism

URL الوصول: http://hdl.handle.net/10616/40744

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2011

المؤلفون: Karoutas, A., Szymanski, W., Rausch, T., Guhathakurta, S., Rog-Zielinska, E. A., Peyronnet, R., Seyfferth, J., Chen, H. R., de Leeuw, R., Herquel, B., Kimura, Hiroshi, Mittler, G., Kohl, P., Medalia, O., Korbel, J. O., Akhtar, A.

المساهمون: University of Zurich, Akhtar, Asifa

المصدر: Nature Cell Biology

مصطلحات موضوعية: Genome instability, Cell Nucleus/metabolism/*ultrastructure, 610 Medicine & health, Epigenesis, Genetic, Histones, 1307 Cell Biology, 03 medical and health sciences, Histone H3, Mice, Nuclear Proteins/genetics/*metabolism, 0302 clinical medicine, Heterochromatin, 10019 Department of Biochemistry, Animals, Epigenetics, Histones/genetics/metabolism, Cells, Cultured, Histone Acetyltransferases, 030304 developmental biology, Cell Nucleus, Mice, Knockout, 0303 health sciences, Chemistry, fungi, Histone Acetyltransferases/genetics/*metabolism, Nuclear Proteins, Acetylation, Cell Biology, Fibroblasts, Lamin Type A, Cell biology, Mice, Inbred C57BL, Lamin Type A/chemistry/genetics/*metabolism, 030220 oncology & carcinogenesis, Acetyltransferase, Nuclear lamina, 570 Life sciences, biology, Lamin, NSL complex

وصف الملف: Karoutas_et_al._2019.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3548ff4d5435a5924760feb5f54ba9
https://doi.org/10.5167/uzh-176015

المؤلفون: Sagelius, Hanna

مصطلحات موضوعية: Progeria -- genetics, Progeria -- metabolism, Progeria -- pathology, Lamin Type A -- genetics, Lamin Type A -- metabolism, Phenotype, Mutation, Hair Follicle -- metabolism, Transcription, Genetic

Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2009

المؤلفون: Alexandra Sousa, Brenda Moura, Roberto Pinto, José Silva Cardoso, José Carlos Machado, Manuel Campelo, José Manuel Lopes, Sérgio Carvalho Leite, Elisabete Martins, Paulo Canedo, Sandra Amorim

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Revista Portuguesa de Cardiologia, Vol 38, Iss 6, Pp 441-447 (2019)
Revista Portuguesa de Cardiologia (English Edition), Vol 38, Iss 6, Pp 441-447 (2019)

مصطلحات موضوعية: Male, lcsh:Diseases of the circulatory (Cardiovascular) system, Genetic variants, TNNT2, medicine.medical_treatment, DNA Mutational Analysis, Dilated cardiomyopathy, 030204 cardiovascular system & hematology, Heart transplantation, LMNA, 0302 clinical medicine, Lamin Type A / genetics, DNA / genetics, 030212 general & internal medicine, General Environmental Science, 0303 health sciences, Cardiomyopathy, Dilated / surgery, High-Throughput Nucleotide Sequencing, Lamin Type A / metabolism, Middle Aged, Lamin Type A, 3. Good health, Phenotype, Female, Cardiology and Cardiovascular Medicine, Cardiomyopathy, Dilated, Adult, Cardiomyopathy, Dilated / genetics, medicine.medical_specialty, DNA sequencing, 03 medical and health sciences, Internal medicine, medicine, Humans, Gene, 030304 developmental biology, business.industry, Genetic Variation, Heterozygote advantage, DNA, medicine.disease, 030228 respiratory system, lcsh:RC666-701, Mutation, Next-generation sequencing, Heart Transplantation, General Earth and Planetary Sciences, business, Follow-Up Studies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9bb647852e193a57702007f8400419
https://hdl.handle.net/10216/136215

المؤلفون: Hirano, Y., Hizume, K., Kimura, Hiroshi, Takeyasu, K., Haraguchi, T., Hiraoka, Y.

المصدر: Journal of Biological Chemistry. 287:42654-42663

مصطلحات موضوعية: Histones/*metabolism, Tudor domain, Transcription, Genetic, Nuclear Envelope, Heterochromatin, Molecular Sequence Data, Receptors, Cytoplasmic and Nuclear, DNA and Chromosomes, Lamin B receptor, Methylation, Models, Biological, Biochemistry, Heterochromatin/*metabolism, Histones, Histone H4, Humans, Histone code, Inner membrane, Lamin Type B/metabolism, Amino Acid Sequence, Molecular Biology, Nuclear Envelope/metabolism, Lamin Type B, biology, Repressor Proteins/metabolism, Lysine, fungi, Cell Biology, Molecular biology, Protein Structure, Tertiary, Chromatin, Cell biology, Repressor Proteins, Receptors, Cytoplasmic and Nuclear/chemistry/*metabolism, Protein Processing, Post-Translational, HEK293 Cells, Histone, biology.protein, sense organs, Protein Multimerization, Lysine/metabolism, HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5390330bef10014bae47d37b6d55b16
https://doi.org/10.1074/jbc.m112.397950

المؤلفون: David Masson, Scott Sayers, Minako Ishibashi, Alan R. Tall, Nan Wang, Marit Westerterp, Rong Li, Carrie L. Welch

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Translational Immunology Groningen (TRIGR)

المصدر: Journal of Lipid Research, 51(9), 2655-2663. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Lipid Research, Vol 51, Iss 9, Pp 2655-2663 (2010)

مصطلحات موضوعية: Apolipoprotein E, receptor, Cholesterol, VLDL, LDL/metabolism, Macrophages, Peritoneal/cytology, Biochemistry, Mice, Endocrinology, hemic and lymphatic diseases, Receptors, Orphan Nuclear Receptors/genetics, polycyclic compounds, nuclear receptor, Cells, Cultured, Research Articles, Liver X Receptors, Mice, Knockout, Cultured, Sterol Regulatory Element Binding Protein 2/genetics, lipoprotein, Serine Endopeptidases, Intracellular Signaling Peptides and Proteins, Lamin Type A, Orphan Nuclear Receptors, Triglycerides/blood, Cholesterol, Liver, Proteins/genetics, Kexin, lipids (amino acids, peptides, and proteins), Proprotein Convertases, Proprotein Convertase 9, Sterol Regulatory Element Binding Protein 1, Niemann-Pick disease, Sterol Regulatory Element Binding Protein 2, medicine.medical_specialty, Cells, Knockout, Ubiquitin-Protein Ligases, Receptors, LDL/metabolism, Serine Endopeptidases/genetics, QD415-436, Biology, Cholesterol/blood, digestive system, Apolipoproteins E, Liver/physiology, Sterol Regulatory Element Binding Protein 1/genetics, Niemann-Pick C1 Protein, Internal medicine, medicine, Animals, Peritoneal/cytology, Cholesterol, VLDL/metabolism, Ubiquitin-Protein Ligases/genetics, Liver X receptor, Triglycerides, Macrophages, PCSK9, Proteins, nutritional and metabolic diseases, VLDL/metabolism, Lamin Type A/metabolism, Cell Biology, Sterol regulatory element-binding protein, Receptors, LDL, LDL receptor, Macrophages, Peritoneal, Sterol regulatory element-binding protein 2, atherosclerosis, Apolipoproteins E/genetics, Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8914b87aacc6512d6f3d88cfea443cfd
https://doi.org/10.1194/jlr.m006163

المؤلفون: Hans-Hinrich Sievers, Nimrat Grewal, Salah A. Mohamed, J.H.N. Lindeman, Adriana C. Gittenberger-de Groot, Robert E. Poelmann, Ad J.J.C. Bogers, Marie-José Goumans, Robert J.M. Klautz, Marco C. DeRuiter, Meindert Palmen

المساهمون: Cardiothoracic Surgery

المصدر: The Journal of Thoracic and Cardiovascular Surgery, 148(4), 1583-90. Mosby Inc.
The Journal of Thoracic and Cardiovascular Surgery, 148(4), 1583-1590
Journal of thoracic and cardiovascular surgery, 148(4), 1583-1590. Mosby Inc.
Journal of Thoracic and Cardiovascular Surgery, 148(4), 1583-1590. Mosby Inc.

مصطلحات موضوعية: Male, Vascular smooth muscle, Biopsy, Heart Valve Diseases, Muscle, Smooth, Vascular/pathology, Aorta, Thoracic, Biomarkers/metabolism, Muscle, Smooth, Vascular, Immunoenzyme Techniques, Bicuspid aortic valve, Bicuspid Aortic Valve Disease, Medicine, Aorta, Aortic Diseases/pathology, Vascular/pathology, biology, Blotting, Heart Valve Diseases/pathology, Nuclear Proteins, Middle Aged, Lamin Type A, Progerin, Protein Precursors/metabolism, Aortic Valve, cardiovascular system, Cardiology, Muscle, Female, Smooth, Cardiology and Cardiovascular Medicine, Western, Dilatation, Pathologic, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Smooth muscle cell differentiation, Calponin, Blotting, Western, Aortic Diseases, medicine.artery, Internal medicine, Ascending aorta, Humans, Protein Precursors, Aged, Nuclear Proteins/metabolism, Pathologic, business.industry, Thoracic/pathology, Aortic Valve/abnormalities, Lamin Type A/metabolism, medicine.disease, Dilatation, biology.protein, Smoothelin, Surgery, business, Aorta, Thoracic/pathology, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0805898f2459bda7ab289ebeadca2203
https://pure.amc.nl/en/publications/ascending-aorta-dilation-in-association-with-bicuspid-aortic-valve(c93fe26f-421f-4330-9a89-dd8467c02861).html

المؤلفون: Francesco A. Manzoli, Giovanna Lattanzi, Alberto Bavelloni, Sandra Marmiroli, Vittoria Cenni, Nadir M. Maraldi

المساهمون: Maraldi NM, Lattanzi G, Cenni V, Bavelloni A, Marmiroli S, Manzoli FA.

مصطلحات موضوعية: Genetics, Cell Nucleus, Cancer Research, Nuclear Envelope, # Cell Nucleus/metabolism # Cell Nucleus/ultrastructure # Disease* # Humans # Lamin Type A/metabolism* # Nuclear Envelope/metabolism # Nuclear Envelope/ultrastructure # Phosphorylation # Signal Transduction/physiology, Biology, Lamin Type A, Chromatin, Cell biology, Cell nucleus, medicine.anatomical_structure, Cytoplasm, medicine, Molecular Medicine, Nuclear lamina, Humans, Disease, Signal transduction, Phosphorylation, Cytoskeleton, Molecular Biology, Transcription factor, Lamin, Signal Transduction

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1770d9ea4d3d926f78a5024b7cb102d4
https://hdl.handle.net/11380/648447