المؤلفون: Langenhorst JB; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Model-informed Drug Development Consultant, Pharmetheus AB, Uppsala, Sweden., Boss J; Hospital Pharmacy, St Jansdal Hospital, Harderwijk, The Netherlands., van Kesteren C; Hospital Pharmacy, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Lalmohamed A; Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Kuball J; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Hematology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Egberts ACG; Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacoepidemiology & Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Boelens JJ; Stem Cell Transplant and Cellular Therapies; Pediatrics, Memorial Sloan Kettering Cancer Centre, New York City, New York, USA., Huitema ADR; Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Maarseveen EM; Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2020 Aug; Vol. 86 (8), pp. 1499-1509. Date of Electronic Publication: 2020 Mar 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Busulfan* , Hematopoietic Stem Cell Transplantation*, Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Drug Monitoring ; Female ; Glutathione ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Young Adult

المؤلفون: Langenhorst JB; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Laboratory of Translational Immunology, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands.; Model-informed drug development consultant, Pharmetheus AB, Uppsala, Sweden., Dorlo TPC; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Kesteren C; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., van Maarseveen EM; Department of Clinical Pharmacy, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands., Nierkens S; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Laboratory of Translational Immunology, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands., de Witte MA; Department of Hematology, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands., Boelens JJ; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Stem Cell Transplant and Cellular Therapies, Pediatrics, Memorial Sloan Kettering Cancer Centre, New York, New York, USA., Huitema ADR; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Clinical Pharmacy, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands.

المصدر: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2020 May; Vol. 9 (5), pp. 272-281. Date of Electronic Publication: 2020 Apr 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Research Design*, Antineoplastic Agents/*administration & dosage , Hematopoietic Stem Cell Transplantation/*methods , Vidarabine/*analogs & derivatives, Adult ; Combined Modality Therapy ; Computer Simulation ; Hematologic Neoplasms/therapy ; Humans ; Randomized Controlled Trials as Topic/methods ; Vidarabine/administration & dosage

المؤلفون: Steen-Louws C; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands.; Department of Rheumatology and Clinical Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Boross P; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Prado J; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Meeldijk J; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Langenhorst JB; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Huitema ADR; Department of Clinical Pharmacy, UMC Utrecht, Utrecht University, Utrecht, Netherlands.; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute, Amsterdam, Netherlands., den Hartog MT; Bioceros Holding B.V., Utrecht, Netherlands., Boon L; Bioceros Holding B.V., Utrecht, Netherlands., Lafeber FPJG; Department of Rheumatology and Clinical Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Hack CE; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Eijkelkamp N; Center for Translational Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands., Popov-Celeketic J; Department of Rheumatology and Clinical Immunology, UMC Utrecht, Utrecht University, Utrecht, Netherlands. J.Popov-Celeketic@umcutrecht.nl.

المصدر: Pharmaceutical research [Pharm Res] 2019 Dec 26; Vol. 37 (2), pp. 17. Date of Electronic Publication: 2019 Dec 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Inflammatory Agents/*blood , Interleukin-10/*blood , Interleukin-4/*blood , N-Acetylneuraminic Acid/*chemistry , Recombinant Fusion Proteins/*blood, Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; CHO Cells ; Cricetulus ; Disease Models, Animal ; Glycosylation ; HEK293 Cells ; Humans ; Interleukin-10/chemistry ; Interleukin-10/pharmacology ; Interleukin-4/chemistry ; Interleukin-4/pharmacology ; Metabolic Clearance Rate ; Mice, Inbred C57BL ; Pain/drug therapy ; Rats, Wistar ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/pharmacology

المؤلفون: Langenhorst JB; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Laboratory of Translational Immunology and., van Kesteren C; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., van Maarseveen EM; Department of Clinical Pharmacy, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands., Dorlo TPC; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/Netherlands Cancer Institute, Amsterdam, The Netherlands., Nierkens S; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Laboratory of Translational Immunology and., Lindemans CA; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., de Witte MA; Laboratory of Translational Immunology and.; Department of Hematology, UMCU, Utrecht University, Utrecht, The Netherlands; and., van Rhenen A; Department of Hematology, UMCU, Utrecht University, Utrecht, The Netherlands; and., Raijmakers R; Department of Hematology, UMCU, Utrecht University, Utrecht, The Netherlands; and., Bierings M; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Kuball J; Laboratory of Translational Immunology and.; Department of Hematology, UMCU, Utrecht University, Utrecht, The Netherlands; and., Huitema ADR; Department of Clinical Pharmacy, University Medical Centre Utrecht (UMCU), Utrecht University, Utrecht, The Netherlands.; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/Netherlands Cancer Institute, Amsterdam, The Netherlands., Boelens JJ; Pediatric Blood and Marrow Transplant Program, Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Stem Cell Transplant and Cellular Therapies, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.

المصدر: Blood advances [Blood Adv] 2019 Jul 23; Vol. 3 (14), pp. 2179-2187.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Hematopoietic Stem Cell Transplantation*/adverse effects , Hematopoietic Stem Cell Transplantation*/methods , Transplantation Conditioning*/adverse effects , Transplantation Conditioning*/methods, Myeloablative Agonists/*therapeutic use , Vidarabine/*analogs & derivatives, Adolescent ; Adult ; Cause of Death ; Female ; Humans ; Male ; Middle Aged ; Mortality ; Myeloablative Agonists/administration & dosage ; Myeloablative Agonists/adverse effects ; Myeloablative Agonists/pharmacokinetics ; Prognosis ; Retrospective Studies ; Risk Factors ; Transplantation, Homologous ; Vidarabine/administration & dosage ; Vidarabine/adverse effects ; Vidarabine/pharmacokinetics ; Vidarabine/therapeutic use ; Young Adult

المؤلفون: Langenhorst JB; Pediatric Blood and Marrow Transplant Program, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Dorlo TPC; Department of Pharmacy and Pharmacology, Antoni van Leeuwenhoek Hospital/Netherlands Cancer Institute, Amsterdam, The Netherlands., van Maarseveen EM; Department of Clinical Pharmacy, University Medical Centre, Utrecht, Utrecht University, Heidelberglaan 100: D.00.X, 3584 CX, Utrecht, The Netherlands., Nierkens S; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Kuball J; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Hematology, University Medical Centre, Utrecht, Utrecht University, Utrecht, The Netherlands., Boelens JJ; Pediatric Blood and Marrow Transplant Program, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Stem Cell Transplant and Cellular Therapies; Pediatrics, Memorial Sloan Kettering Cancer Centre, New York, NY, USA., van Kesteren C; Pediatric Blood and Marrow Transplant Program, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Huitema ADR; Department of Pharmacy and Pharmacology, Antoni van Leeuwenhoek Hospital/Netherlands Cancer Institute, Amsterdam, The Netherlands. a.d.r.huitema-2@umcutrecht.nl.; Department of Clinical Pharmacy, University Medical Centre, Utrecht, Utrecht University, Heidelberglaan 100: D.00.X, 3584 CX, Utrecht, The Netherlands. a.d.r.huitema-2@umcutrecht.nl.

المصدر: Clinical pharmacokinetics [Clin Pharmacokinet] 2019 May; Vol. 58 (5), pp. 627-637.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Models, Biological*, Myeloablative Agonists/*pharmacokinetics , Vidarabine/*analogs & derivatives, Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Hematopoietic Stem Cell Transplantation ; Humans ; Infant ; Male ; Middle Aged ; Transplantation Conditioning ; Vidarabine/pharmacokinetics ; Young Adult

المؤلفون: Punt AM; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: a.m.punt@umcutrecht.nl., Langenhorst JB; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., Egas AC; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., Boelens JJ; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., van Kesteren C; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., van Maarseveen EM; Department of Clinical Pharmacy, Division of Laboratory Medicine and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.

المصدر: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2017 Jun 15; Vol. 1055-1056, pp. 81-85. Date of Electronic Publication: 2017 Apr 15.

نوع المنشور: Journal Article; Validation Study

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Adenine Nucleotides/*blood , Antineoplastic Agents/*blood , Arabinonucleosides/*blood , Busulfan/*blood , Drug Monitoring/*methods , Immunosuppressive Agents/*blood , Tandem Mass Spectrometry/*methods , Vidarabine/*analogs & derivatives, Chromatography, Liquid/methods ; Clofarabine ; Hematopoietic Stem Cell Transplantation ; Humans ; Isotopes/blood ; Limit of Detection ; Transplantation Conditioning ; Vidarabine/blood