نتائج البحث - "Lasse Kjellerup"

المصدر: Clausen, J D, Kjellerup, L, Cohrt, K OH, Hansen, J B, Dalby-Brown, W & Winther, A-M L 2017, ' Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives ', Bioorganic & Medicinal Chemistry Letters, vol. 27, no. 19, pp. 4564-4570 . https://doi.org/10.1016/j.bmcl.2017.08.067
Bioorganic & Medicinal Chemistry Letters

مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, Inhibitor, Stereochemistry, ATPase, 030106 microbiology, Clinical Biochemistry, Carbazoles, Carbazole, Pharmaceutical Science, Microbial Sensitivity Tests, Antifungal, Biochemistry, Article, H(+)-K(+)-Exchanging ATPase, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Candida albicans, Drug Discovery, medicine, Na+/K+-ATPase, Molecular Biology, Ion transporter, ComputingMethodologies_COMPUTERGRAPHICS, Dose-Response Relationship, Drug, Molecular Structure, Bacteria, biology, Chemistry, Organic Chemistry, Proton Pump Inhibitors, Adenosine, Proton pump, Yeast, Calcium ATPase, Adenosine diphosphate, 030104 developmental biology, Membrane protein, biology.protein, Molecular Medicine, Adenosine triphosphate, Intracellular, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7cd679d9f480980cb44ea43fc7b45d
https://doi.org/10.1016/j.bmcl.2017.08.067

View record from ScienceDirect

4

HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides

المؤلفون: Aml Winther, Kenneth T. Kongstad, Lasse Kjellerup, Sileshi Gizachhew Wubshet, Dan Staerk

المصدر: Planta Medica. 81:S1-S381

مصطلحات موضوعية: Pharmacology, Fungicide, Chromatography, Complementary and alternative medicine, Chemistry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Hplc hrms, High resolution, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c9a22cd5df1e72f409242a639da59090
https://doi.org/10.1055/s-0036-1596273

5

Novel zinc-attenuating compounds as potent broad-spectrum antifungal agents with in vitro and in vivo efficacy

المؤلفون: Laura Marín, Anne-Marie Lund Winther, Lasse Kjellerup, William Dalby-Brown, José Antonio Calera, Karen A. O'Hanlon Cohrt, Johannes D. Clausen

المساهمون: Innovation Fund Denmark, Pcovery, Consejo Superior de Investigaciones Científicas (España), Universidad de Salamanca, Wellcome Trust, Boehringer Ingelheim Fonds, Ministerio de Economía y Competitividad (España), Kjellerup, Lasse, Lund Winther, Anne-Marie, Kjellerup, Lasse [0000-0002-7855-3567], Lund Winther, Anne-Marie [0000-0002-5776-0989]

المصدر: GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
Antimicrobial Agents and Chemotherapy
Digital.CSIC. Repositorio Institucional del CSIC
Cohrt, K A OH, Marín, L, Kjellerup, L, Clausen, J D, Dalby-Brown, W, Antonio Calera, J & Winther, A-M L 2018, ' Novel zinc-attenuating compounds as potent broad-spectrum antifungal agents with In Vitro and In Vivo efficacy ', Antimicrobial Agents and Chemotherapy, vol. 62, no. 5, e02024-17 . https://doi.org/10.1128/AAC.02024-17

مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, 030106 microbiology, Microbial Sensitivity Tests, Pharmacology, Antifungal, Aspergillus fumigatus, Mice, 03 medical and health sciences, Drug Resistance, Fungal, In vivo, Instituto de Biología Funcional y Genómica, Zinc deprivation, Cell Line, Tumor, Yeasts, Candida albicans, medicine, Animals, Aspergillosis, Humans, Pharmacology (medical), Mode of action, Mechanisms of Action: Physiological Effects, Mice, Inbred BALB C, Antifungals, biology, Chemistry, Drug discovery, Candidiasis, Hep G2 Cells, biology.organism_classification, In vitro, Yeast, 3. Good health, Proton-Translocating ATPases, Infectious Diseases, Mechanism of action, Drug development, Zinc Compounds, medicine.symptom, antifungal, Zinc homeostasis

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c177540d77100e16b977e5e30050db1
http://hdl.handle.net/10261/182769

6

Cyclic AMP Pathway Activation and Extracellular Zinc Induce Rapid Intracellular Zinc Mobilization in

المؤلفون: Lasse, Kjellerup, Anne-Marie L, Winther, Duncan, Wilson, Anja T, Fuglsang

المصدر: Frontiers in Microbiology

مصطلحات موضوعية: ER, cAMP, zinc, Candida albicans, signaling, Microbiology, Original Research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1b4cfafae117277b2a8680af245139b6
https://pubmed.ncbi.nlm.nih.gov/29619016

7

Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv

المؤلفون: Anne-Marie Lund Winther, Dan Staerk, Sileshi Gizachew Wubshet, Kenneth T. Kongstad, Lasse Kjellerup

المصدر: Fitoterapia. 105:102-106

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43e7bb85d45e356057f8b23a3b58cd5
https://doi.org/10.1016/j.fitote.2015.06.013

View record from ScienceDirect

8

Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity

المؤلفون: William Dalby-Brown, Anne-Marie Lund Winther, Johannes D. Clausen, Thomas David Pallin, Anne Louise Mortensen, Karen O'Hanlon Cohrt, Maike Bublitz, John Bondo Hansen, Anja T. Fuglsang, Lasse Kjellerup, Sandra Gordon

المصدر: PLoS ONE
Bublitz, M, Kjellerup, L, Cohrt, K OH, Gordon, S, Mortensen, A L, Clausen, J D, Pallin, T D, Hansen, J B, Fuglsang, A T, Dalby-Brown, W & Winther, A-M L 2018, ' Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity ', PLOS ONE, vol. 13, no. 1, e0188620 . https://doi.org/10.1371/journal.pone.0188620
PLoS ONE, Vol 13, Iss 1, p e0188620 (2018)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Adenosine Triphosphatase, Antifungal Agents, ATPase, Cell Membranes, lcsh:Medicine, Yeast and Fungal Models, Crystallography, X-Ray, Pathology and Laboratory Medicine, Biochemistry, Membrane Potentials, chemistry.chemical_compound, Adenosine Triphosphate, ATP hydrolysis, Chemical reactions, Microbial Physiology, Medicine and Health Sciences, Enzyme Inhibitors, lcsh:Science, Candida, Fungal Pathogens, Multidisciplinary, Crystallography, biology, Molecular Structure, Antimicrobials, Hydrolysis, Physics, Microbial Growth and Development, Eukaryota, Drugs, Hep G2 Cells, Condensed Matter Physics, 3. Good health, Enzymes, Chemistry, Experimental Organism Systems, Medical Microbiology, Physical Sciences, Crystal Structure, Saccharomyces Cerevisiae, Pathogens, Cellular Structures and Organelles, medicine.drug, Research Article, Fungal Growth, SERCA, Stereochemistry, 030106 microbiology, Carbazoles, Microbial Sensitivity Tests, Mycology, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Saccharomyces, Model Organisms, Microbial Control, medicine, Humans, Candida Albicans, Solid State Physics, Homology modeling, Binding site, Microbial Pathogens, Pharmacology, Antifungals, lcsh:R, Organisms, Fungi, Phosphatases, Biology and Life Sciences, Proteins, Cell Biology, Adenosine, Yeast, 030104 developmental biology, chemistry, P-type ATPases, biology.protein, P-type ATPase, Enzymology, lcsh:Q, Drug Screening Assays, Antitumor, Adenosine triphosphate, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82b8c2b948adb1cd53bd7ce9a466e8a
https://pubmed.ncbi.nlm.nih.gov/29293507

Find this article in full text from ProQuest

9

Identification of antifungal H+-ATPase inhibitors with effect on the plasma membrane potential

المؤلفون: Karen O'Hanlon Cohrt, Sandra Gordon, Anja T. Fuglsang, Anne-Marie Lund Winther, William Dalby Brown, Lasse Kjellerup

المصدر: Kjellerup, L, Gordon, S, Cohrt, K OH, Brown, W D, Fuglsang, A T & Winther, A-M L 2017, ' Identification of antifungal H +-ATPase inhibitors with effect on the plasma membrane potential ', Antimicrobial Agents and Chemotherapy, vol. 61, no. 7, e00032-17 . https://doi.org/10.1128/AAC.00032-17
Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, Saccharomyces cerevisiae Proteins, ATPase, membrane proteins, Peptide, Saccharomyces cerevisiae, 01 natural sciences, Membrane Potentials, 03 medical and health sciences, Journal Article, Humans, Pharmacology (medical), Mode of action, Mechanisms of Action: Physiological Effects, Pharmacology, Membrane potential, chemistry.chemical_classification, Fungal protein, biology, 010405 organic chemistry, Chemistry, Cell Membrane, Hep G2 Cells, drug development, 0104 chemical sciences, 3. Good health, Proton-Translocating ATPases, 030104 developmental biology, Infectious Diseases, Membrane, Biochemistry, Membrane protein, biology.protein, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0824bf72e11b63e28b0853acbd6c7b07
https://curis.ku.dk/portal/da/publications/identification-of-antifungal-hatpase-inhibitors-with-effect-on-the-plasma-membrane-potential(3cc9b6d9-2d05-41f0-b5da-99bfc6aee5c3).html

10

High-Resolution Screening Combined with HPLC-HRMS-SPE-NMR for Identification of Fungal Plasma Membrane H+-ATPase Inhibitors from Plants

المؤلفون: Kenneth T. Kongstad, Anne-Marie Lund Winther, Lasse Kjellerup, Ane Johannesen, Dan Staerk, Sileshi Gizachew Wubshet, Anna K. Jäger

المصدر: Journal of Agricultural and Food Chemistry. 62:5595-5602

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a1b20070b71e6fff27d78a66dd9272
https://doi.org/10.1021/jf501605z

Find this issue from the American Chemical Society

تنقيح النتائج