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1دورية أكاديمية
المؤلفون: Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2دورية أكاديمية
المؤلفون: Peter C. Ray, Margaret Huggett, Penelope A. Turner, Malcolm Taylor, Laura A. T. Cleghorn, Julie Early, Anuradha Kumar, Shilah A. Bonnett, Lindsay Flint, Douglas Joerss, James Johnson, Aaron Korkegian, Steven Mullen, Abraham L. Moure, Susan H. Davis, Dinakaran Murugesan, Michael Mathieson, Nicola Caldwell, Curtis A. Engelhart, Dirk Schnappinger, Ola Epemolu, Fabio Zuccotto, Jennifer Riley, Paul Scullion, Laste Stojanovski, Lisa Massoudi, Gregory T. Robertson, Anne J. Lenaerts, Gail Freiberg, Dale J. Kempf, Thierry Masquelin, Philip A. Hipskind, Joshua Odingo, Kevin D. Read, Simon R. Green, Paul G. Wyatt, Tanya Parish
المصدر: ACS Omega, Vol 6, Iss 3, Pp 2284-2311 (2021)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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3دورية أكاديمية
المؤلفون: Stephen Patterson, Susan Wyllie, Suzanne Norval, Laste Stojanovski, Frederick RC Simeons, Jennifer L Auer, Maria Osuna-Cabello, Kevin D Read, Alan H Fairlamb
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: Leishmania donovani, Visceral leishmaniasis, drug repurposing, pharmacokinetics, pharmacodynamics, OPC-67683, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Caterina Pont, Elisabet Viayna, Stephen Brand, Ian H. Gilbert, Peter George Dodd, Iva Lukac, Laste Stojanovski, Maria Osuna-Cabello, Jennifer Riley, Sujatha Manthri, Kate McGonagle, Timothy J. Miles, Julio Martin, Fabio Zuccotto, Frederick R. C. Simeons, John Thomas, Maria L. Marco, Paul G. Wyatt, Kevin D. Read, Stephen Thompson, Jose M. Fiandor, Michael G. Thomas, Manu De Rycker, Eun-Jung Ko
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Pyridines, Phenotypic screening, In silico, Antiprotozoal Agents, Drug Evaluation, Preclinical, Protozoan Proteins, Computational biology, Molecular Dynamics Simulation, Scaffold hopping, 01 natural sciences, Article, Cell Line, 03 medical and health sciences, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, East africa, Animals, Humans, 030304 developmental biology, 0303 health sciences, Binding Sites, Drug discovery, Chemistry, medicine.disease, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Protein Subunits, Visceral leishmaniasis, Proteasome, Solubility, Drug Design, Molecular Medicine, Leishmaniasis, Visceral, Proteasome Inhibitors, Half-Life, Leishmania donovani
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المؤلفون: Alasdair Smith, Richard J. Wall, Stephen Patterson, Tim Rowan, Eva Rico Vidal, Laste Stojanovski, Margaret Huggett, Shahienaz E. Hampton, Michael G. Thomas, Victoriano Corpas Lopez, Kirsten Gillingwater, Jeff Duke, Grant Napier, Rose Peter, Hervé S. Vitouley, Justin R. Harrison, Rachel Milne, Laura Jeacock, Nicola Baker, Susan H. Davis, Frederick Simeons, Jennifer Riley, David Horn, Reto Brun, Fabio Zuccotto, Michael J Witty, Susan Wyllie, Kevin D. Read, Ian H. Gilbert
المصدر: Journal of medicinal chemistry. 65(7)
مصطلحات موضوعية: Trypanosomiasis, African, Trypanosoma congolense, Drug Discovery, Drug Repositioning, Molecular Medicine, Animals, Cattle, Trypanosoma vivax, Cyclin-Dependent Kinases
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المؤلفون: Tanya Parish, Lindsay Flint, Anuradha Kumar, Lisa M. Massoudi, Paul Scullion, Gregory T. Robertson, Shilah A. Bonnett, Simon Green, Nicola Caldwell, Jennifer Riley, Gail M. Freiberg, Philip Arthur Hipskind, Michael Mathieson, Thierry Masquelin, Laste Stojanovski, Curtis A. Engelhart, Margaret Huggett, Dinakaran Murugesan, Abraham Lopez Moure, Fabio Zuccotto, Julie V. Early, Ola Epemolu, Paul G. Wyatt, Dale J. Kempf, Kevin D. Read, Susan Davis, Laura A. T. Cleghorn, James Johnson, Steven Mullen, Malcolm Taylor, Anne J. Lenaerts, Penelope A. Turner, Peter C. Ray, Joshua Odingo, Dirk Schnappinger, Aaron Korkegian, Douglas Joerss
المصدر: ACS Omega
ACS Omega, Vol 6, Iss 3, Pp 2284-2311 (2021)مصطلحات موضوعية: 0303 health sciences, Tuberculosis, biology, 030306 microbiology, Chemistry, General Chemical Engineering, Phenotypic screening, hERG, General Chemistry, Pharmacology, medicine.disease, biology.organism_classification, In vitro, Article, 3. Good health, Mycobacterium tuberculosis, 03 medical and health sciences, Minimum inhibitory concentration, In vivo, biology.protein, medicine, Cytotoxicity, QD1-999, 030304 developmental biology
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7دورية أكاديمية
المؤلفون: Susan Wyllie, Michael Thomas, Stephen Patterson, Sabrinia Crouch, Manu Rycker, Rhiannon Lowe, Stephanie Gresham, Michael D. Urbaniak, Thomas D. Otto, Laste Stojanovski, Frederick R. C. Simeo
المصدر: Nature, Nature. 619(7970):48-48
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المؤلفون: Caroline Wilson, Peter Ray, Fabio Zuccotto, Jorge Hernandez, Anup Aggarwal, Claire Mackenzie, Nicola Caldwell, Malcolm Taylor, Margaret Huggett, Michael Mathieson, Dinakaran Murugesan, Alasdair Smith, Susan Davis, Mattia Cocco, Maloy K. Parai, Arjun Acharya, Fabio Tamaki, Paul Scullion, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Eva Maria Lopez-Román, Pedro Alfonso Torres-Gómez, Ana Maria Toledo, Laura Guijarro-Lopez, Isabel Camino, Curtis A. Engelhart, Dirk Schnappinger, Lisa M. Massoudi, Anne Lenaerts, Gregory T. Robertson, Chris Walpole, David Matthews, David Floyd, James C. Sacchettini, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Simon R. Green, Paul G. Wyatt
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Models, Molecular, 0303 health sciences, ERG1 Potassium Channel, 010405 organic chemistry, Antitubercular Agents, Heart, Microbial Sensitivity Tests, Mycobacterium tuberculosis, 01 natural sciences, Cardiotoxicity, Article, 0104 chemical sciences, 3. Good health, 03 medical and health sciences, Structure-Activity Relationship, Bacterial Proteins, Palmitoyl-CoA Hydrolase, Piperidines, Drug Discovery, Molecular Medicine, Humans, Polyketide Synthases, 030304 developmental biology, Benzofurans
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المؤلفون: Michael G. Thomas, Maria L. Marco, John Thomas, Daniel Spinks, Ian H. Gilbert, Laste Stojanovski, Frederick R. C. Simeons, Ola Epemolu, Sujatha Manthri, Claire Naylor, Timothy J. Miles, Manu De Rycker, Suzanne Norval, Susan Wyllie, Stephen Patterson, Jennifer Riley, Maria Osuna-Cabello, Richard J. Wall, Jose M. Fiandor, Paul G. Wyatt, Kevin D. Read, Stephen Thompson
المصدر: Journal of Medicinal Chemistry. 63:9523-9539
مصطلحات موضوعية: 0303 health sciences, Chemistry, Pharmacology, medicine.disease, 01 natural sciences, Parasitic infection, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Visceral leishmaniasis, In vivo, Drug Discovery, Toxicity, medicine, Molecular Medicine, Water chemistry, Structure–activity relationship, Inhibitory concentration 50, 030304 developmental biology
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المؤلفون: Kevin D. Read, Sabrinia D. Crouch, Juan Miguel-Siles, Stephen Thompson, Lorna MacLean, Timothy J. Miles, Franck Martin, Alain Claude-Marie Daugan, Suzanne Norval, Laste Stojanovski, Gloria Fra, John Thomas, Frederick R. C. Simeons, Sujatha Manthri, Jose M. Fiandor, César Guerrero, Myriam Ajakane, Maria Osuna-Cabello, Paul G. Wyatt, Manu De Rycker, Lorna Campbell, Claire J. MacKenzie, Ian H. Gilbert, Jennifer Riley, Yoko Shishikura, Michael G. Thomas, Raul F. Velasco
المصدر: RSC Medicinal Chemistry. 11:1168-1177
مصطلحات موضوعية: Pharmacology, 0303 health sciences, 030306 microbiology, business.industry, Organic Chemistry, Pharmaceutical Science, medicine.disease, Biochemistry, 03 medical and health sciences, Visceral leishmaniasis, In vivo, Drug Discovery, medicine, Molecular Medicine, Identification (biology), business, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::907889087930243eaf8e578bd0ada172
https://doi.org/10.1039/d0md00203h
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