المؤلفون: Doris Chen, Wanjia Yu, Laura Aitken, Frank Gunn-Moore

المصدر: Cells, Vol 11, Iss 19, p 3140 (2022)

مصطلحات موضوعية: Willin/FRMD6, mitochondrial dysfunction, oxidative stress, Alzheimer’s disease, neurodegeneration, ERK signaling, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/19/3140; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/7d185684c8e1456ab5284790b1d8a5a9

المؤلفون: Ondrej Benek, Lukas Hroch, Laura Aitken, Frank Gunn-Moore, Lucie Vinklarova, Kamil Kuca, Daniel I. Perez, Concepcion Perez, Ana Martinez, Zdenek Fisar, Kamil Musilek

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 665-670 (2018)

مصطلحات موضوعية: Alzheimer’s disease, amyloid-beta binding alcohol dehydrogenase (ABAD), benzothiazole, casein kinase 1 (CK1), neurodegeneration, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/e6a3739db0ac4249892a19629268c016

المؤلفون: Doris Chen, Wanjia Yu, Laura Aitken, Frank Gunn-Moore

المصدر: Cells, Vol 10, Iss 11, p 3024 (2021)

مصطلحات موضوعية: Willin/FRMD6, Hippo signaling, Alzheimer’s disease, neurodegeneration, mechanotransduction, oxidative stress, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/11/3024; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/b67184628280410783fae04e19b9810c

المؤلفون: Monika Schmidt, Ondrej Benek, Lucie Vinklarova, Martina Hrabinova, Lucie Zemanova, Matej Chribek, Vendula Kralova, Lukas Hroch, Rafael Dolezal, Antonin Lycka, Lukas Prchal, Daniel Jun, Laura Aitken, Frank Gunn-Moore, Kamil Kuca, Kamil Musilek

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 6, p 2059 (2020)

مصطلحات موضوعية: neurodegeneration, alzheimer’s disease, 17β-hydroxysteroid dehydrogenase type 10, abad, inhibitor, benzothiazole, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/6/2059; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/791a9647fb064038aebddfb79664380c

المؤلفون: Laura Aitken, Ondrej Benek, Brogan E. McKelvie, Rebecca E. Hughes, Lukas Hroch, Monika Schmidt, Louise L. Major, Lucie Vinklarova, Kamil Kuca, Terry K. Smith, Kamil Musilek, Frank J. Gunn-Moore

المصدر: Molecules, Vol 24, Iss 15, p 2757 (2019)

مصطلحات موضوعية: Alzheimer’s disease (AD), amyloid-beta peptide (Aβ), mitochondria, 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), amyloid binding alcohol dehydrogenase (ABAD), benzothiazole, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/15/2757; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/c039f8abf9114eae9e6a20208c4c6e80

المؤلفون: Karina Vitanova, Gayle H. Doherty, Rona R. Ramsay, Matthew J. Buchan, Ying Cheng, Laura Aitken, Frank J. Gunn-Moore

المساهمون: University of St Andrews. School of Psychology and Neuroscience, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex, University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis, University of St Andrews. Centre for Biophotonics, University of St Andrews. Institute of Behavioural and Neural Sciences

المصدر: Journal of Neurochemistry. 155:191-206

مصطلحات موضوعية: Leptin, 0301 basic medicine, FIS1, MFN2, Mitochondrion, Biology, Hippocampus, Mitochondrial Dynamics, Biochemistry, Neuroprotection, Cell Line, GTP Phosphohydrolases, Mitochondrial Proteins, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Mitochondrial fusion, Hippocampal, Animals, Humans, Inner mitochondrial membrane, Monoamine Oxidase, Ischemic Stroke, Amyloid beta-Peptides, Mitochondrial fission, Monoamine oxidase, DAS, Peptide Fragments, Mitochondria, Cell biology, Glucose, Neuroprotective Agents, 030104 developmental biology, mitochondrial fusion, Mitochondrial Membranes, RC0321, Reactive Oxygen Species, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae53fcbfef891931f123660ff771ea6
https://doi.org/10.1111/jnc.15003

المؤلفون: Frank J. Gunn-Moore, Wanjia Yu, Doris Chen, Laura Aitken

المصدر: Cells, Vol 10, Iss 3024, p 3024 (2021)
Cells

مصطلحات موضوعية: Nervous system, QH301-705.5, Regulator, Down-Regulation, Review, Biology, Pathogenesis, Willin/FRMD6, Alzheimer Disease, medicine, Humans, oxidative stress, Mechanotransduction, Biology (General), mechanotransduction, Neurons, Hippo signaling, Neurodegeneration, neurodegeneration, Membrane Proteins, General Medicine, medicine.disease, Actin cytoskeleton, Phenotype, medicine.anatomical_structure, Neuroscience, Alzheimer’s disease, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ac0bcf7bfac2c0df9f22dee4f17104
https://www.mdpi.com/2073-4409/10/11/3024

المؤلفون: Jana Janockova, Jana Kubackova, Karel Vales, Petr Jost, João Pina, Zuzana Bednarikova, Jan Korabecny, Katarina Motykova, Eugenie Nepovimova, Luísa Cortes, Zofia Chrienova, Kamil Musilek, Carlos Serpa, Rafael Dolezal, Lucie Svobodova, Lucie Junova, Laura Aitken, Vendula Hepnarova, Martin Vališ, Katarina Chalupova, Ondrej Soukup, Danijela Rostohar, Marketa Chvojkova, Daniel Jun, Lubica Muckova, Catarina S. H. Jesus, Zuzana Gazova, Kamil Kuca, Rebecca E. Hughes, Tomas Kucera

المصدر: Bioorganic chemistry. 107

مصطلحات موضوعية: Amyloid, Cholinergic Agents, Pharmacology, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Protein Aggregates, Structure-Activity Relationship, In vivo, Alzheimer Disease, Drug Discovery, medicine, Humans, Benzothiazoles, Enzyme Inhibitors, Molecular Biology, IC50, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, 3-Hydroxyacyl CoA Dehydrogenases, Acetylcholinesterase, In vitro, 0104 chemical sciences, Mitochondria, 010404 medicinal & biomolecular chemistry, Neuroprotective Agents, Benzothiazole, chemistry, Tacrine, Cholinergic, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a8a38c3acadad44401b27e8e3bfeba
https://pubmed.ncbi.nlm.nih.gov/33421953

المؤلفون: Concepción Pérez, Daniel I. Perez, Zdenek Fisar, Lukas Hroch, Ondrej Benek, Kamil Kuca, Frank J. Gunn-Moore, Kamil Musilek, Ana Martínez, Laura Aitken, Lucie Vinklarova

المساهمون: National Institute of Mental Health (Czech Republic), University of Hradec Králové, Rosetrees Trust, Biotechnology and Biological Sciences Research Council (UK), Ministerio de Economía y Competitividad (España), University of St Andrews. School of Biology, University of St Andrews. Institute of Behavioural and Neural Sciences, University of St Andrews. Biomedical Sciences Research Complex

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 665-670 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Enzyme Inhibition and Medicinal Chemistry

مصطلحات موضوعية: 0301 basic medicine, Short Communication, QH301 Biology, NDAS, Library science, Amyloid-beta binding alcohol dehydrogenase (ABAD), Structure-Activity Relationship, QH301, 03 medical and health sciences, 0302 clinical medicine, Political science, Drug Discovery, Humans, QD, Benzothiazoles, Enzyme Inhibitors, Neurodegeneration, Biological sciences, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Casein Kinase I, Phenylurea Compounds, lcsh:RM1-950, neurodegeneration, 3-Hydroxyacyl CoA Dehydrogenases, Neurodegenerative Diseases, benzothiazole, General Medicine, Alzheimer's disease, Benzothiazole, QD Chemistry, 3. Good health, casein kinase 1 (CK1), Casein kinase 1 (CK1), lcsh:Therapeutics. Pharmacology, 030104 developmental biology, Research council, RC0321, amyloid-beta binding alcohol dehydrogenase (ABAD), Christian ministry, Casein kinase 1, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Alzheimer’s disease, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165ba45be77aced7ee46436b66b4ee64
https://doi.org/10.1080/14756366.2018.1445736

المؤلفون: Terry K. Smith, Angus Morrison, Philip S. Jones, Andrew D. Pannifer, Stuart P. McElroy, Laura Aitken, Frank J. Gunn-Moore, Gemma L. Baillie

المساهمون: Rosetrees Trust, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex, University of St Andrews. Institute of Behavioural and Neural Sciences

المصدر: SLAS Discovery. 22:676-685

مصطلحات موضوعية: 0301 basic medicine, RM, Chemical Phenomena, QH301 Biology, NDAS, Peptide, In Vitro Techniques, Biology, Pharmacology, Ligands, 01 natural sciences, Biochemistry, Analytical Chemistry, QH301, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Alzheimer Disease, Drug Discovery, Humans, Cytotoxic T cell, ligand binding [Pharmacology], Enzyme Inhibitors, Enzyme Assays, Alcohol dehydrogenase, chemistry.chemical_classification, Ultra-high throughput screening, Enzyme assays or enzyme kinetics, Neurodegenerative diseases, 3-Hydroxyacyl CoA Dehydrogenases, Reproducibility of Results, Metabolism, Small molecule, In vitro, RM Therapeutics. Pharmacology, High-Throughput Screening Assays, 0104 chemical sciences, Kinetics, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Enzyme, Drug development, chemistry, RC0321, biology.protein, Molecular Medicine, Receptor binding, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Protein Binding, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fb33157ea39d89368f777833bd160e
https://doi.org/10.1177/2472555217697964