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1
المؤلفون: Y. Joy Yu Zuchero, William H Montgomery, Laura DeForge, William J. Meilandt, Kwame Hoyte, Wilman Luk, Dongping He, Ryan J. Watts, Jasvinder K. Atwal, Kimberly Scearce-Levie, Yanmei Lu
المصدر: Bioanalysis. 8:1067-1075
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Clinical Biochemistry, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Endogeny, Transferrin receptor, Disease, Analytical Chemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Antibodies, Bispecific, Drug Discovery, Receptors, Transferrin, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, Medicine, General Pharmacology, Toxicology and Pharmaceutics, Amyloid beta-Peptides, biology, business.industry, Brain, General Medicine, Peptide Fragments, Disease Models, Animal, Medical Laboratory Technology, 030104 developmental biology, Drug development, Immunology, biology.protein, Cancer research, Biomarker (medicine), Amyloid Precursor Protein Secretases, Antibody, business, Biomarkers, 030217 neurology & neurosurgery
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2
المؤلفون: Eric Suto, Wei Yu Lin, Flavius Martin, Sami McVay, Allen Nguyen, Ali A. Zarrin, Mercedesz Balazs, Wyne P. Lee, Yonglian Sun, Laura DeForge, Patrick Caplazi, Dhaya Seshasayee, Zhonghua Lin
المصدر: Arthritis & Rheumatology (Hoboken, N.j.)
مصطلحات موضوعية: Cyclophosphamide, medicine.medical_treatment, Immunology, Cell Count, Systemic Lupus Erythematosus, Mice, Rheumatology, immune system diseases, B-Cell Activating Factor, medicine, Animals, Lupus Erythematosus, Systemic, Immunology and Allergy, skin and connective tissue diseases, BAFF receptor, B-cell activating factor, B cell, Autoantibodies, B-Lymphocytes, Systemic lupus erythematosus, Lupus erythematosus, Mice, Inbred NZB, Terpenes, business.industry, Incidence, Antibodies, Monoclonal, Interferon-alpha, Immunotherapy, Acute Kidney Injury, Antigens, CD20, medicine.disease, Blockade, Disease Models, Animal, Treatment Outcome, medicine.anatomical_structure, Female, business, B-Cell Activation Factor Receptor, medicine.drug
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3
المؤلفون: Laura DeForge, Eric Suto, Justin Lesch, Joseph W. Lubach, Arna Katewa, Zora Modrusan, Tao Huang, Allen Nguyen, Harvey Wong, Lichuan Liu, Jianyong Wang, Jason A. Hackney, James J. Crawford, Adam R. Johnson, Chungkee Poon, Sami McVay, Jacob Z. Chen, Zhonghua Lin, Yugang Wang, Marya Liimatta, Jason DeVoss, Peter Blomgren, Kevin S. Currie, Karin Reif, Wendy B. Young, Cary D. Austin, Michael J. Townsend, Nandhini Ramamoorthi, Jonathan Hau, Julie DiPaolo, Meire Bremer, Wyne P. Lee
المصدر: JCI Insight. 2
مصطلحات موضوعية: 0301 basic medicine, Myeloid, Plasma Cells, Lupus nephritis, Gene Expression, Kidney, Lymphocyte Activation, Mice, 03 medical and health sciences, immune system diseases, Agammaglobulinaemia Tyrosine Kinase, medicine, Animals, Humans, Bruton's tyrosine kinase, Myeloid Cells, skin and connective tissue diseases, B-cell activating factor, B cell, Autoantibodies, Cell Proliferation, B-Lymphocytes, Systemic lupus erythematosus, Mice, Inbred NZB, biology, business.industry, Interferon-alpha, Glomerulonephritis, General Medicine, medicine.disease, Lupus Nephritis, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Immunology, biology.protein, Female, business, Nephritis, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495b8b0af6744c8645b436f824312ac
https://doi.org/10.1172/jci.insight.90111 -
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المؤلفون: Kelly M. Loyet, Lisa A. Damico-Beyer, Jeremy Good, Kha Le, Xiangdan Wang, Philip E. Hass, Laura DeForge, Teresa Davancaze, Jihong Yang, Alyssa Morimoto, Lizette Sturgeon, Menno van Lookeren Campagne, Maureen Wong, Peter Haughney
المصدر: Journal of Pharmacology and Experimental Therapeutics. 351:527-537
مصطلحات موضوعية: Male, Pharmacology, Lampalizumab, Immunoglobulin Fab Fragments, Macular Degeneration, Mice, medicine, Animals, Humans, Antigen Binding Fragment, Serine protease, Dose-Response Relationship, Drug, biology, business.industry, Macular degeneration, medicine.disease, Complement inhibition, Macaca fascicularis, Dose–response relationship, Treatment Outcome, Intravitreal Injections, Immunology, Complement C3a, biology.protein, Alternative complement pathway, Molecular Medicine, Cattle, Complement Factor D, Female, Factor D, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff87804fcd99c185604a27c050704d1f
https://doi.org/10.1124/jpet.114.215921 -
5
المؤلفون: Robert F. Kelley, Laura DeForge, Kyra J. Cowan, Maya Leabman, Y. Gloria Meng, Suhasini Iyer
المصدر: mAbs. 5:896-903
مصطلحات موضوعية: Glycosylation, Immunology, Enzyme-Linked Immunosorbent Assay, Receptors, Fc, Plasma protein binding, Pharmacology, chemistry.chemical_compound, Cricetinae, Report, Animals, Immunology and Allergy, Receptor, chemistry.chemical_classification, Dose-Response Relationship, Drug, biology, Chinese hamster ovary cell, Wild type, Antibodies, Monoclonal, Genetic Variation, Molecular biology, Fragment crystallizable region, Amino acid, Macaca fascicularis, chemistry, biology.protein, Antibody, Protein Binding
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6
المؤلفون: Mercedesz Balazs, Donghong Yan, Maria N. Lorenzo, Tao Sai, Laura DeForge, Kajal Hamidzadeh, Andrew Sebrell, Yan Qu, Jin Zhaoyu, Merone Roose-Girma, Meijuan Zhou, Patrick Caplazi, Wyne P. Lee, Min Xu, Yonglian Sun, Zhonghua Lin, Kate Senger, Wei Yu Lin, Jiabing Ding, Shahram Misaghi, Allen Nguyen, Ali A. Zarrin, Søren Warming, Cary D. Austin, Vishva M. Dixit
المصدر: Proceedings of the National Academy of Sciences. 110:15770-15775
مصطلحات موضوعية: Recombination hotspot, Lymphocyte Activation, Immunoglobulin E, Mice, Activation-induced (cytidine) deaminase, Animals, Gene Knock-In Techniques, RNA, Messenger, Alleles, Recombination, Genetic, Genetics, B-Lymphocytes, Hybridomas, Multidisciplinary, biology, Immunoglobulin mu-Chains, Gene targeting, Cytidine deaminase, Biological Sciences, Immunoglobulin Class Switching, Germ Cells, Immunoglobulin class switching, Genetic Loci, Gene Targeting, Models, Animal, biology.protein, Immunoglobulin epsilon-Chains, Antibody, Recombination
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba4e540cf59a6dd15e59e52d423e521
https://doi.org/10.1073/pnas.1221661110 -
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المؤلفون: Alexander W. Koch, Ben-Quan Shen, Yanmei Lu, Laura DeForge, Raymond K. Tong, Daniela Bumbaca, Hong Xiang
المصدر: Bioanalysis. 4:703-711
مصطلحات موضوعية: Time Factors, Recombinant Fusion Proteins, Clinical Biochemistry, Enzyme-Linked Immunosorbent Assay, Semaphorins, Biology, High-performance liquid chromatography, Antibodies, Analytical Chemistry, Mice, In vivo, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Polyacrylamide gel electrophoresis, Chromatography, High Pressure Liquid, Antitumor activity, Protein Stability, Intact protein, General Medicine, Molecular biology, In vitro, Immunoglobulin Fc Fragments, Medical Laboratory Technology, Fc fusion, Electrophoresis, Chromatography, Gel, Electrophoresis, Polyacrylamide Gel, Female
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8
المؤلفون: Saileta Prabhu, Jeff Lutman, Yanmei Lu, Rong Deng, Y. Gloria Meng, Laura DeForge, Frank-Peter Theil, Suhasini Iyer, Paul J. Fielder, Kwame Hoyte
المصدر: mAbs. 4:101-109
مصطلحات موضوعية: medicine.drug_class, Injections, Subcutaneous, Immunology, Antibody Affinity, Biological Availability, Mice, SCID, Receptors, Fc, Pharmacology, Monoclonal antibody, Immunoglobulin G, Mice, Neonatal Fc receptor, Report, medicine, Animals, Humans, Immunology and Allergy, biology, Catabolism, Chemistry, Histocompatibility Antigens Class I, Potential effect, Antibodies, Monoclonal, Bioavailability, biology.protein, Antibody, Function (biology), Protein Binding
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9
المؤلفون: Juan Zhang, Wyne P. Lee, Vishva M. Dixit, Kate Senger, Allen Nguyen, Donghong Yan, Maria N. Lorenzo, Yonglian Sun, Shahram Misaghi, Sherry Heldens, Ali A. Zarrin, Tao Sai, Christopher Garris, Jiansheng Wu, Laura DeForge, Andrew Sebrell, Min Xu
المصدر: The Journal of Immunology. 185:166-173
مصطلحات موضوعية: Immunology, B-Lymphocyte Subsets, Somatic hypermutation, Immunoglobulin E, Mice, chemistry.chemical_compound, Animals, Humans, Immunology and Allergy, Repeated sequence, Cells, Cultured, Recombination, Genetic, biology, Cytidine deaminase, Immunoglobulin Class Switching, Molecular biology, Mice, Mutant Strains, Immunoglobulin Switch Region, Immunoglobulin Isotypes, Mice, Inbred C57BL, Immunoglobulin class switching, chemistry, Gene Targeting, biology.protein, Somatic Hypermutation, Immunoglobulin, Antibody, Gene Deletion, Recombination, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788509bc98407279ad87b0a2df615a66
https://doi.org/10.4049/jimmunol.1000515 -
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المؤلفون: Jane L. Grogan, Xin Yu, Allen Nguyen, Ganesh Kolumam, Eugene Chiang, Judy Young, Nathan Wei, Wai Lee Wong, Catherine Kung, Kristen Wolslegel, Laura DeForge, Michael J. Townsend
المصدر: Cytokine. 51:78-86
مصطلحات موضوعية: Male, T-Lymphocytes, medicine.medical_treatment, Immunology, Matrix metalloproteinase, Lymphocyte Activation, Biochemistry, Proinflammatory cytokine, Arthritis, Rheumatoid, Synovitis, Synovial Fluid, medicine, Humans, Immunology and Allergy, Synovial fluid, Molecular Biology, Aged, Demography, Aged, 80 and over, Chemistry, Lymphotoxin alpha1, beta2 Heterotrimer, Hematology, Fibroblasts, Middle Aged, medicine.disease, Cytokine, Lymphotoxin, Solubility, Rheumatoid arthritis, Metalloproteases, Female, Tumor necrosis factor alpha, Chemokines, Cell Adhesion Molecules