يعرض 1 - 10 نتائج من 11 نتيجة بحث عن '"Laurence Queguiner"', وقت الاستعلام: 1.01s تنقيح النتائج
  1. 1
    Use of 3-(Pentafluorosulfanyl)phenol to Access to Advanced Substituted Pentafluorosulfanylphenol/anisole: Application to the Synthesis of 2-(Arylpentafluorosulfanyl)indanedione

    المؤلفون: Sabrina Quatrevaux, Jerome Guillemont, Sandrine Gaurrand, Laurence Queguiner, Michaut Antoine Benjamin

    المصدر: Letters in Organic Chemistry. 19:602-607

    مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Organic Chemistry, Organic chemistry, Phenol, Anisole, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a52ef4d6059ca313646009520f88196b
    https://doi.org/10.2174/1570178618666210218211831

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  2. 2
    Ion mobility-mass spectrometry analysis of diarylquinoline diastereomers: Drugs used for tuberculosis treatment

    المؤلفون: Laurence Queguiner, Carlos Afonso, Jerome Guillemont, Eric Arnoult, David Speybrouck, Virginie Domalain, Marie Hubert-Roux, Dany Jeanne Dit Fouque

    المساهمون: Chimie Organique et Bioorganique : Réactivité et Analyse (COBRA), Institut Normand de Chimie Moléculaire Médicinale et Macromoléculaire (INC3M), Institut de Chimie du CNRS (INC)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Université Le Havre Normandie (ULH), Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Institut de Chimie du CNRS (INC)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie Organique Fine (IRCOF), Université de Rouen Normandie (UNIROUEN), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Janssen-Cilag [Val-de-Reuil], Janssen-Cilag [Issy-les-Moulineaux]

    المصدر: European Journal of Mass Spectrometry
    European Journal of Mass Spectrometry, IM Publications, 2019, 25 (3), pp.291-299. ⟨10.1177/1469066718813226⟩

    مصطلحات موضوعية: Ion-mobility spectrometry, Antitubercular Agents, Protonation, 010402 general chemistry, Tandem mass spectrometry, Mass spectrometry, 01 natural sciences, Adduct, Ion, Computational chemistry, Diarylquinolines, Ion Mobility Spectrometry, Humans, Tuberculosis, [CHIM]Chemical Sciences, Spectroscopy, Molecular Structure, Chemistry, 010401 analytical chemistry, Diastereomer, Stereoisomerism, General Medicine, Atomic and Molecular Physics, and Optics, 3. Good health, 0104 chemical sciences

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193463214cb8e11c02132a54dc59c707
    https://hal-normandie-univ.archives-ouvertes.fr/hal-02330535

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  3. 3
    Minisci-Photoredox-Mediated α-Heteroarylation of N-Protected Secondary Amines: Remarkable Selectivity of Azetidines

    المؤلفون: Laurence Queguiner, Guillaume Bretel, Cyril Henry, Ann Vos, Hélène Beucher, James P. Edwards, Lieven Meerpoel, Didier Berthelot, Cyril Bosset, Elisabeth Thérèse Jeanne Pasquier

    المصدر: Organic letters. 20(19)

    مصطلحات موضوعية: Scope (project management), 010405 organic chemistry, Chemistry, Organic Chemistry, Surface modification, Physical and Theoretical Chemistry, 010402 general chemistry, Selectivity, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189ad85334f051f21c017039098a038b
    https://pubmed.ncbi.nlm.nih.gov/30252482

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  4. 4
    Synthesis and Biological Evaluation of C-5 Methyl Substituted 4-Arylthio and 4-Aryloxy-3-Iodopyridin-2(1H)-one Type Anti-HIV Agents

    المؤلفون: Marie-Pierre de Béthune, Said Oumouch, Patrice Palandjian, Jerome Emile Georges Guillemont, Daniel Vernier, Kurt Hertogs, Koen Andries, Chi Hung Nguyen, Laurence Queguiner, David S. Grierson, Abdellah Benjahad, Laurence F B Decrane

    المصدر: Journal of medicinal chemistry

    مصطلحات موضوعية: Iodopyridones, Anti-HIV Agents, Stereochemistry, Mutant, Chemical synthesis, Cell Line, Small Molecule Libraries, Inhibitory Concentration 50, Drug Discovery, medicine, Humans, chemistry.chemical_classification, Reverse-transcriptase inhibitor, biology, Wild type, HIV, HIV Reverse Transcriptase, In vitro, Chemistry, Enzyme, chemistry, Enzyme inhibitor, Mutation, biology.protein, Molecular Medicine, Lactone, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4b3260eeaf39908174f455f48fc404
    https://doi.org/10.1021/jm900802y

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  5. 5
    Discovery of pyrimidyl-5-hydroxamic acids as new potent histone deacetylase inhibitors

    المؤلفون: Peter ten Holte, Boudewijn Janssens, Sandrine Gaurrand, Janine Arts, Jacky van Gompel, Virginie Sophie Poncelet, Patrick Angibaud, Ann Marien, Hans De Winter, Bruno Roux, An Aerts, Verdonck Marc Gustaaf Celine, Jacky Van Dun, Luc Van Hijfte, Kristof Van Emelen, Isabelle Noëlle Constance Pilatte, Eddy Jean Edgard Freyne, Wim Floren, Michel Janicot, Sven Franciscus Anna Van Brandt, Jean-Michel Argoullon, Laurence Queguiner

    المصدر: European Journal of Medicinal Chemistry. 40:597-606

    مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Stereochemistry, medicine.drug_class, Hydroxamic Acids, Inhibitory Concentration 50, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Cell Proliferation, Pharmacology, Histone deacetylase 5, Hydroxamic acid, Molecular Structure, biology, HDAC11, Histone deacetylase 2, HDAC10, Organic Chemistry, Histone deacetylase inhibitor, General Medicine, Histone Deacetylase Inhibitors, Pyrimidines, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Female, Histone deacetylase, HeLa Cells

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdbd08dce8f647012c95f1517777f59
    https://doi.org/10.1016/j.ejmech.2005.01.008

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  6. 6
    Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors

    المؤلفون: Bruno Roux, Luc Van Hijfte, Jacky van Gompel, Claire Mackie, Sven Franciscus Anna Janssen Pharm. Van Brandt, Marc Noppe, Ann Marien, David Speybrouck, Lut Janssen, Marc Du Jardin, Wim Floren, Eddy Jean Edgard Freyne, Michel Janicot, Kristof Van Emelen, Jacky Van Dun, Ron Gilissen, Isabelle Noëlle Constance Pilatte, Virginie Sophie Poncelet, Patrick Angibaud, Verdonck Marc Gustaaf Celine, Peter ten Holte, Sandrine Gaurrand, Martin John Page, Jozef Peeters, Laurence Decrane, Janine Arts, Laurence Queguiner

    المصدر: Bioorganicmedicinal chemistry letters. 20(1)

    مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Mice, Nude, Antineoplastic Agents, Hydroxamic Acids, Biochemistry, Histone Deacetylases, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Cytotoxicity, Molecular Biology, Cell Proliferation, chemistry.chemical_classification, Hydroxamic acid, biology, Organic Chemistry, Histone deacetylase inhibitor, Xenograft Model Antitumor Assays, Rats, Histone Deacetylase Inhibitors, Enzyme, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Histone deacetylase

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc639d3fe98001df6eb7f54901be8937
    https://pubmed.ncbi.nlm.nih.gov/19906529

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  7. 7
    Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121)

    المؤلفون: Philippe Muller, Pieter Van Remoortere, Rudy Edmond Willebrords, Fortin Jerome Michel Claude, Tom Valerius Josepha Gevers, Koen Andries, Christophe Meyer, Piet Wigerinck, Heidi Szel, Jean-François Bonfanti, Janssens Frans Eduard, Philip Timmerman, Frederic Marc Maurice Doublet, Peggy Janssens, Koen Wuyts, Laurence Queguiner

    المصدر: Journal of medicinal chemistry

    مصطلحات موضوعية: Male, Models, Molecular, Paramyxoviridae, Pyridines, Morpholines, Fusion inhibitor, Computational biology, Antiviral Agents, Virus, Rats, Sprague-Dawley, Structure-Activity Relationship, Drug Discovery, Drug Resistance, Viral, Structure–activity relationship, Animals, Sigmodontinae, Mononegavirales, Binding Sites, biology, Chemistry, Pharmacology. Therapy, Virus Internalization, biology.organism_classification, Rats, Respiratory Syncytial Viruses, Sprague dawley, Biochemistry, Mutation, Molecular Medicine, Benzimidazoles, Viral Fusion Proteins, Protein Binding

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bccd604791964784d9bd96c5c4ca306
    https://pubmed.ncbi.nlm.nih.gov/18254606

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  8. 8
    Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship

    المؤلفون: Jerome Emile Georges Guillemont, Koen Wuyts, Heidi Szel, Peggy Janssens, Laurence Queguiner, Fortin Jerome Michel Claude, Eric Arnoult, Philippe Muller, Jean Fernand Armand Lacrampe, Frederic Marc Maurice Doublet, Cois Sommen, Rudy Edmond Willebrords, Jean-François Bonfanti, Philip Timmerman, Tom Valerius Josepha Gevers, Koen Andries, Piet Wigerinck, Janssens Frans Eduard

    المصدر: Journal of medicinal chemistry

    مصطلحات موضوعية: Male, Benzimidazole, Paramyxoviridae, Pyridines, Pharmacology, Kidney, Antiviral Agents, Virus, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Pharmacokinetics, Piperidines, In vivo, Drug Discovery, Animals, Humans, Tissue Distribution, Mononegavirales, Lung, biology, Pharmacology. Therapy, biology.organism_classification, In vitro, Rats, Respiratory Syncytial Viruses, Biochemistry, chemistry, Liver, Molecular Medicine, Benzimidazoles, Lead compound, Viral Fusion Proteins, HeLa Cells

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6cc63268acb0f4afb491d6fe86b844
    https://pubmed.ncbi.nlm.nih.gov/17722899

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  9. 9
    Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains

    المؤلفون: Christophe Gabriel Marcel Demestre, Benoit Antoine Schmitt, Céline Isabelle Mordant, Laurence Queguiner, C. Masungi, Paul J. Lewi, Jerome Emile Georges Guillemont, Elisabeth Thérèse Jeanne Pasquier, Anik Peeters, Liesbeth Smeulders, Kurt Hertogs, Eva Bettens, Jan Heeres

    المصدر: European journal of medicinal chemistry. 42(5)

    مصطلحات موضوعية: Male, Nevirapine, Efavirenz, Magnetic Resonance Spectroscopy, Virus, Mass Spectrometry, chemistry.chemical_compound, Dogs, Drug Discovery, Nitriles, medicine, Animals, Rats, Wistar, Chromatography, High Pressure Liquid, Diarylpyrimidines, Pharmacology, Reverse-transcriptase inhibitor, Chemistry, Organic Chemistry, Rilpivirine, Wild type, virus diseases, General Medicine, Virology, Reverse transcriptase, Rats, Pyrimidines, Biochemistry, HIV-1, Reverse Transcriptase Inhibitors, Female, Spectrophotometry, Ultraviolet, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa4c8f26ea76d8cb85c08edce10577a
    https://pubmed.ncbi.nlm.nih.gov/17223230

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  10. 10
    دورية أكاديمية
    Synthesis and Biological Evaluation of C-5 Methyl Substituted 4-Arylthio and 4-Aryloxy-3-Iodopyridin-2(1H)-one Type Anti-HIV Agents†.

    المؤلفون: Jérôme Guillemont, Abdellah Benjahad, Said Oumouch, Laurence Decrane, Patrice Palandjian, Daniel Vernier, Laurence Queguiner, Koen Andries, Marie-Pierre de Béthune, Kurt Hertogs, David S. Grierson, Chi Hung Nguyen

    المصدر: Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7473-7487, 15p

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