المؤلفون: Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight, Rachael A. Ralli, Sang-Kyu Kim, Kellie-Marie Banks, Eva Vidacs, Clemence Virely, Keith C.S. Sia, Lauryn S. Bracken, Racquel Collins-Underwood, Christina Drenberg, Laura B. Ramsey, Sara C. Meyer, Megumi Takiguchi, Ross A. Dickins, Ross Levine, Jacques Ghysdael, Mark A. Dawson, Richard B. Lock, Charles G. Mullighan, Ricky W. Johnstone

المصدر: Cell Reports, Vol 5, Iss 4, Pp 1047-1059 (2013)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713006372; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/038b13b134c84948ae45ebf210800b23

المؤلفون: Richard B. Lock, Malcolm A. Smith, Peter J. Houghton, Stephen P. Hunger, Mignon L. Loh, Cheryl L. Willman, Charles G. Mullighan, Catherine A. Billups, Raushan T. Kurmasheva, Kathryn G. Roberts, Philipp A. Dietrich, Kathryn Evans, I-Ming Chen, Hernan Carol, Keith C.S. Sia, Richard C. Harvey, Lauryn S. Bracken, Santi Suryani

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3368725252e9fbbf2a94692c84a5b21
https://doi.org/10.1158/1535-7163.22503796

المؤلفون: Kathryn Evans, Raushan T. Kurmasheva, William R. Wilson, Donya Moradi Manesh, Ashlee Hedrick, Catherine A. Billups, Cara E. Toscan, Hernan Carol, Peter J. Houghton, Glenn M. Marshall, Jennifer Richmond, Rosemary Sutton, Lauryn S. Bracken, Jad El-Hoss, Malcolm A. Smith, Richard B. Lock

المصدر: Blood. 126:1193-1202

مصطلحات موضوعية: Male, Vincristine, 3-Hydroxysteroid Dehydrogenases, Adolescent, Cell Survival, T cell, Immunoblotting, Immunology, Antineoplastic Agents, Pharmacology, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Real-Time Polymerase Chain Reaction, Biochemistry, Mice, chemistry.chemical_compound, In vivo, Biomarkers, Tumor, medicine, Animals, Humans, Child, Sensitization, Lymphoid Neoplasia, business.industry, Aldo-Keto Reductase Family 1 Member C3, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Nitrogen mustard, Transplantation, Leukemia, medicine.anatomical_structure, chemistry, Child, Preschool, Nitrogen Mustard Compounds, Hydroxyprostaglandin Dehydrogenases, Cancer research, Biomarker (medicine), Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faefe87e0309154c0ba137f5e67fddf1
https://doi.org/10.1182/blood-2014-12-618900

المؤلفون: Kathryn Evans, Raushan T. Kurmasheva, Cheryl L. Willman, Lauryn S. Bracken, Richard B. Lock, Hernan Carol, Peter J. Houghton, Keith C.S. Sia, Mignon L. Loh, Charles G. Mullighan, Santi Suryani, Stephen P. Hunger, Catherine A. Billups, Kathryn G. Roberts, Malcolm A. Smith, I-Ming Chen, Richard C. Harvey, Philipp A. Dietrich

المصدر: Molecular Cancer Therapeutics. 14:364-374

مصطلحات موضوعية: Cancer Research, Cell Survival, MAP Kinase Signaling System, Biopsy, Pharmacology, Article, Mice, In vivo, medicine, Animals, Humans, Molecular Targeted Therapy, Child, Protein Kinase Inhibitors, Genetic Association Studies, Janus Kinases, Gene Expression Regulation, Leukemic, business.industry, MEK inhibitor, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Xenograft Model Antitumor Assays, In vitro, Gene expression profiling, Pyrimidines, Treatment Outcome, Cell killing, medicine.anatomical_structure, Oncology, Mutation, Selumetinib, Pyrazoles, Benzimidazoles, Bone marrow, Janus kinase, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f00a78f238c9a1a9141a7e6dccf9d7
https://doi.org/10.1158/1535-7163.mct-14-0647

المؤلفون: Jun Yuan, Ning Xu, Karen L. MacKenzie, Rosemary O'Brien, Richard B. Lock, Carlotta Petti, Chen Yang, Tao Liu, Chin-Yi Kan, Michelle F. Maritz, Lauryn S. Bracken

المصدر: The Journal of biological chemistry. 288(17)

مصطلحات موضوعية: Telomerase, Survivin, Inhibitor of apoptosis, medicine.disease_cause, Response Elements, Biochemistry, Inhibitor of Apoptosis Proteins, medicine, E2F1, Humans, Myofibroblasts, Molecular Biology, Psychological repression, neoplasms, Caspase, Cyclin-Dependent Kinase Inhibitor p16, Cell Line, Transformed, biology, E2F1 Transcription Factor, Molecular Bases of Disease, Cell Biology, Up-Regulation, Oxidative Stress, Cell Transformation, Neoplastic, Cancer research, biology.protein, Carcinogenesis, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68768501bf0129078d566261f97e666
https://pubmed.ncbi.nlm.nih.gov/23449974

المؤلفون: Jennifer Richmond, Lauryn S. Bracken, Raushan T. Kurmasheva, Kathryn Evans, Peter J. Houghton, Malcolm A. Smith, Richard B. Lock, Alissa Robbins, Santi Suryani

المصدر: Cancer Research. 75:3276-3276

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Navitoclax, Oncogene, business.industry, Chronic lymphocytic leukemia, Cancer, Nod, medicine.disease, Clinical trial, chemistry.chemical_compound, Basal (phylogenetics), chemistry, In vivo, Internal medicine, Immunology, medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4661e25be58a22a38a5b9f9fbb390890
https://doi.org/10.1158/1538-7445.am2015-3276

المؤلفون: Richard B. Lock, Peter J. Houghton, Raushan T. Kurmasheva, Hernan Carol, Santi Suryani, Keith C.S. Sia, Malcolm A. Smith, Kathryn Evans, Lauryn S. Bracken

المصدر: Blood. 120:3562-3562

مصطلحات موضوعية: MAPK/ERK pathway, business.industry, Immunology, JAK-STAT signaling pathway, Cell Biology, Hematology, Pharmacology, Biochemistry, Cell killing, In vivo, STAT protein, Medicine, business, Janus kinase, Protein kinase B, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5e7a9824812549e01eb0f06cac6a95b0
https://doi.org/10.1182/blood.v120.21.3562.3562

المؤلفون: Sara C. Meyer, Mark A. Dawson, Charles G. Mullighan, Megumi Takiguchi, Rachael A Ralli, Richard B. Lock, Racquel Collins-Underwood, Sang-Kyu Kim, Ross A. Dickins, Jacques Ghysdael, Lauryn S. Bracken, Eva Vidacs, Vanessa S. Solomon, Clemence Virely, Ross L. Levine, Deborah A. Knight, Ricky W. Johnstone, Keith C.S. Sia, Laura B. Ramsey, Christina D. Drenberg, Michaela Waibel, Kellie-Marie Banks

المصدر: Cell Reports
Cell Reports, Vol 5, Iss 4, Pp 1047-1059 (2013)
Cell reports

مصطلحات موضوعية: MAPK/ERK pathway, BH3 Mimetic ABT-737, Mutant, Apoptosis, Mice, SCID, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Piperazines, Nitrophenols, Mice, 0302 clinical medicine, Mice, Inbred NOD, hemic and lymphatic diseases, lcsh:QH301-705.5, STAT5, 0303 health sciences, Sulfonamides, Janus kinase 2, biology, Bcl-2-Like Protein 11, food and beverages, 3. Good health, Biphenyl compound, 030220 oncology & carcinogenesis, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Cell Survival, Transplantation, Heterologous, bcl-X Protein, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Cell Line, Tumor, Proto-Oncogene Proteins, Nitriles, Animals, Humans, PI3K/AKT/mTOR pathway, 030304 developmental biology, Gene Expression Profiling, Biphenyl Compounds, Membrane Proteins, Janus Kinase 2, Transplantation, Mice, Inbred C57BL, Pyrimidines, lcsh:Biology (General), Drug Resistance, Neoplasm, Cancer research, biology.protein, Pyrazoles, Apoptosis Regulatory Proteins, Neoplasm Transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dc501d0e7ec2e1586a258336c2f3a2