المؤلفون: Laverty DJ; Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Gupta SK; Mayo Clinic, Rochester, MN, 55905, USA., Bradshaw GA; Harvard Medical School, Boston, MA, 02115, USA., Hunter AS; Harvard Medical School, Boston, MA, 02115, USA., Carlson BL; Mayo Clinic, Rochester, MN, 55905, USA., Calmo NM; Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Chen J; Mayo Clinic, Rochester, MN, 55905, USA.; Shengjing Hospital of China Medical University, Shenyang, 110004, China., Tian S; Mayo Clinic, Rochester, MN, 55905, USA., Sarkaria JN; Mayo Clinic, Rochester, MN, 55905, USA., Nagel ZD; Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. znagel@hsph.harvard.edu.

المصدر: Nature communications [Nat Commun] 2024 Jun 21; Vol. 15 (1), pp. 5294. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ataxia Telangiectasia Mutated Proteins*/metabolism , Ataxia Telangiectasia Mutated Proteins*/antagonists & inhibitors , Ataxia Telangiectasia Mutated Proteins*/genetics , Glioblastoma*/genetics , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Glioblastoma*/pathology , Tumor Suppressor Protein p53*/metabolism , Tumor Suppressor Protein p53*/genetics , DNA Breaks, Double-Stranded*/drug effects , Temozolomide*/pharmacology, Humans ; Cell Line, Tumor ; Mutation ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/drug effects ; DNA Repair/drug effects ; Brain Neoplasms/genetics ; Brain Neoplasms/drug therapy ; Brain Neoplasms/pathology ; Brain Neoplasms/metabolism ; Animals ; DNA End-Joining Repair/drug effects ; Mice ; Phosphorylation/drug effects

المؤلفون: Rona G; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY 10016, USA., Miwatani-Minter B; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Zhang Q; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Goldberg HV; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Kerzhnerman MA; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Howard JB; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Simoneschi D; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Lane E; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Hobbs JW; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Sassani E; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Wang AA; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Keegan S; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA; Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA., Laverty DJ; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Piett CG; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pongor LS; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Cancer Genomics and Epigenetics Core Group, Hungarian Centre of Excellence for Molecular Medicine, Szeged 6728, Hungary., Xu ML; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Andrade J; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Thomas A; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Sicinski P; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, Chalubinskiego 5, 02-004 Warsaw, Poland., Askenazi M; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Biomedical Hosting LLC, 33 Lewis Avenue, Arlington, MA 02474, USA., Ueberheide B; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Fenyö D; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA; Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA., Nagel ZD; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pagano M; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY 10016, USA. Electronic address: michele.pagano@nyulangone.org.

المصدر: Molecular cell [Mol Cell] 2024 Apr 04; Vol. 84 (7), pp. 1224-1242.e13. Date of Electronic Publication: 2024 Mar 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cyclins*/genetics , DNA Mismatch Repair*, Animals ; Proliferating Cell Nuclear Antigen/genetics ; Proliferating Cell Nuclear Antigen/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Interphase ; Mammals/metabolism

المؤلفون: Chen J; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Shengjing Hospital of China Medical University, Shenyang 110004, China., Laverty DJ; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Talele S; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55905, USA., Bale A; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Bakken KK; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Decker PA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA., Vaubel RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Eckel-Passow JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA., Bhargava R; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.; Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Lou Z; Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA., Hamerlik P; AstraZeneca, Cambridge, UK., Harley B; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Elmquist WF; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55905, USA., Nagel ZD; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Gupta SK; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.

المصدر: Science translational medicine [Sci Transl Med] 2024 Feb 14; Vol. 16 (734), pp. eadj5962. Date of Electronic Publication: 2024 Feb 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism , Glioblastoma*/drug therapy , Glioblastoma*/genetics , Glioblastoma*/radiotherapy , Pyridines* , Quinolones*, Humans ; Signal Transduction ; DNA Repair/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism

المؤلفون: Rona G; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA.; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY 10016, USA., Miwatani-Minter B; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Zhang Q; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Goldberg HV; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Kerzhnerman MA; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Howard JB; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Simoneschi D; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Lane E; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Hobbs JW; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Sassani E; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Wang AA; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Keegan S; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA.; Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA., Laverty DJ; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Piett CG; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pongor LS; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Hungarian Centre of Excellence for Molecular Medicine, University of Szeged, Szeged, H-6728, Hungary., Xu ML; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Andrade J; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Thomas A; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Sicinski P; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA.; Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, Chalubinskiego 5, 02-004 Warsaw, Poland., Askenazi M; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Biomedical Hosting LLC, 33 Lewis Avenue, Arlington, MA 02474, USA., Ueberheide B; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA., Fenyö D; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA.; Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA., Nagel ZD; Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pagano M; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY 10016, USA.; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY 10016, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 13. Date of Electronic Publication: 2024 Jan 13.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Vassel FM; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Laverty DJ; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA., Bian K; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Piett CG; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA., Hemann MT; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Walker GC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Nagel ZD; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair* , DNA Replication*, Animals ; Mice ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Mad2 Proteins/genetics ; Mad2 Proteins/metabolism ; Mitosis/genetics

المؤلفون: Lu H; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX75390, USA., Zhang Q; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX75390, USA., Laverty DJ; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA02115, USA., Puncheon AC; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX75390, USA., Augustine MM; Division of Surgical Oncology, Department of Surgery, UT Southwestern Medical Center, Dallas, TX75390, USA.; Department of Surgery, North Texas VA Medical Center, Dallas, TX75216, USA., Williams GJ; Department of Biochemistry and Molecular Biology, Robson DNA Science Centre, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Nagel ZD; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA02115, USA., Chen BPC; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX75390, USA., Davis AJ; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX75390, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jul 21; Vol. 51 (13), pp. 6770-6783.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Activated Protein Kinase*/genetics , Ataxia Telangiectasia*, Humans ; DNA Repair ; Threonine/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; DNA End-Joining Repair ; DNA/genetics

المؤلفون: Lu H, Zhang Q, Laverty DJ, Puncheon AC, Williams GJ, Nagel ZD, Chen BP, Davis AJ

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 02. Date of Electronic Publication: 2023 Feb 02.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Yuhas SC, Laverty DJ, Lee H, Majumdar A, Greenberg MM

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2022 Feb 16; Vol. 144 (6), pp. 2825. Date of Electronic Publication: 2022 Feb 03.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Piett CG; Department of Environmental Health, JBL Center for Radiation Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Pecen TJ; Department of Environmental Health, JBL Center for Radiation Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Laverty DJ; Department of Environmental Health, JBL Center for Radiation Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Nagel ZD; Department of Environmental Health, JBL Center for Radiation Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, USA. znagel@hsph.harvard.edu.

المصدر: Nature protocols [Nat Protoc] 2021 Sep; Vol. 16 (9), pp. 4265-4298. Date of Electronic Publication: 2021 Aug 06.

نوع المنشور: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair* , Genes, Reporter* , Genetic Techniques*, Plasmids/*chemical synthesis, Humans

المؤلفون: Nguyen MT; Case Western Reserve University, Department of Biochemistry, Cleveland, OH, 44106, USA., Moiani D; Departments of Cancer Biology and of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcomb Blvd, Houston, TX, 77030, USA., Ahmed Z; Departments of Cancer Biology and of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcomb Blvd, Houston, TX, 77030, USA., Arvai AS; Integrative Structural & Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA., Namjoshi S; Departments of Cancer Biology and of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcomb Blvd, Houston, TX, 77030, USA., Shin DS; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Fedorov Y; Case Small-Molecule Screening Core, School of Medicine, Case Western Reserve University, Cleveland, OH, 44016, USA., Selvik EJ; Department of Pharmaceutical Sciences, The University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR, 72205, USA., Jones DE; Department of Pharmaceutical Sciences, The University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR, 72205, USA., Pink J; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA., Yan Y; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA., Laverty DJ; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, 02115, USA., Nagel ZD; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, 02115, USA., Tainer JA; Departments of Cancer Biology and of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcomb Blvd, Houston, TX, 77030, USA; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. Electronic address: JTainer@mdanderson.org., Gerson SL; Case Western Reserve University, Department of Biochemistry, Cleveland, OH, 44106, USA; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA. Electronic address: Slg5@case.edu.

المصدر: Progress in biophysics and molecular biology [Prog Biophys Mol Biol] 2021 Aug; Vol. 163, pp. 143-159. Date of Electronic Publication: 2021 Mar 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0401233 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1732 (Electronic) Linking ISSN: 00796107 NLM ISO Abbreviation: Prog Biophys Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair* , Uracil-DNA Glycosidase*/genetics , Uracil-DNA Glycosidase*/metabolism, Catalytic Domain ; Cytidine Deaminase ; DNA Damage ; Humans ; Minor Histocompatibility Antigens ; Uracil