المؤلفون: Bettegowda, C, Sausen, M, Leary, RJ, Kinde, I, Wang, YX, Agrawal, N, Bartlett, BR, Wang, H, Luber, B, Alani, RM, Antonarakis, ES, Azad, NS, Bardelli, A, Brem, H, Cameron, JL, Lee, CC, Fecher, LA, Gallia, GL, Gibbs, P, Le, D, Giuntoli, RL, Goggins, M, Hogarty, MD, Holdhoff, M, Hong, SM, Jiao, YC, Juhl, HH, Kim, JJ, Siravegna, G, Laheru, DA, Lauricella, C, Lim, M, Lipson, EJ, Marie, SKN, Netto, GJ, Oliner, KS, Olivi, A, Olsson, L, Riggins, GJ, Sartore-Bianchi, A, Schmidt, K, Shih, IM, Oba-Shinjo, SM, Siena, S, Theodorescu, D, Tie, JN, Harkins, TT, Veronese, S, Wang, TL, Weingart, JD, Wolfgang, CL, Wood, LD, Xing, DM, Hruban, RH, Wu, J, Allen, PJ, Schmidt, CM, Choti, MA, Velculescu, VE, Kinzler, KW, Vogelstein, B, Papadopoulos, N, Luis, AJ

المصدر: Science translational medicine. 6(224)

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:128408322

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المؤلفون: Fairchild L; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Whalen J; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., D'Aco K; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Wu J; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Gustafson CB; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Solovieff N; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Su F; Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA., Leary RJ; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Campbell CD; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA., Balbin OA; Novartis Institutes for BioMedical Research Inc., Cambridge, MA 02139, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Mar 29; Vol. 15 (689), pp. eabm8729. Date of Electronic Publication: 2023 Mar 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Cell-Free Nucleic Acids*/genetics , Neoplasms*/pathology, Humans ; Clonal Hematopoiesis/genetics ; Hematopoiesis/genetics ; Inflammation ; Sequence Analysis, DNA ; Mutation/genetics ; Tumor Microenvironment

المؤلفون: Orlando EJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA. elena.orlando@novartis.com., Han X; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA., Tribouley C; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA., Wood PA; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA., Leary RJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Riester M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Levine JE; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Qayed M; Aflac Cancer and Blood Disorders Center, Emory University, Atlanta, GA, USA., Grupp SA; Divison of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Boyer M; University of Utah, Salt Lake City, UT, USA., De Moerloose B; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., Nemecek ER; Oregon Health & Science University, Portland, OR, USA., Bittencourt H; Sainte-Justine University Health Center, Montreal, Quebec, Canada., Hiramatsu H; Department of Pediatrics, Kyoto University, Kyoto, Japan., Buechner J; Department of Pediatric Hematology and Oncology, Oslo University Hospital, Oslo, Norway., Davies SM; Divison of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Verneris MR; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Nguyen K; Navigate BioPharma Services, Inc., A Novartis Subsidiary, Carlsbad, CA, USA., Brogdon JL; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Bitter H; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Morrissey M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Pierog P; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA., Pantano S; Novartis Pharma AG, Basel, Switzerland., Engelman JA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Winckler W; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.

المصدر: Nature medicine [Nat Med] 2018 Oct; Vol. 24 (10), pp. 1504-1506. Date of Electronic Publication: 2018 Oct 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm/*genetics , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Receptors, Antigen, T-Cell/*genetics , Receptors, Chimeric Antigen/*genetics, Antigens, CD19/genetics ; Antigens, CD19/immunology ; Humans ; Immunotherapy, Adoptive ; Loss of Heterozygosity/genetics ; Mutation ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/immunology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Receptors, Chimeric Antigen/immunology ; Receptors, Chimeric Antigen/therapeutic use ; T-Lymphocytes/immunology

المؤلفون: Dagogo-Jack I; Department of Medicine, Massachusetts General Hospital, Boston, MA., Brannon AR; Novartis Institutes of BioMedical Research, Cambridge, MA., Ferris LA; Department of Medicine, Massachusetts General Hospital, Boston, MA., Campbell CD; Novartis Institutes of BioMedical Research, Cambridge, MA., Lin JJ; Department of Medicine, Massachusetts General Hospital, Boston, MA., Schultz KR; Department of Medicine, Massachusetts General Hospital, Boston, MA., Ackil J; Department of Medicine, Massachusetts General Hospital, Boston, MA., Stevens S; Department of Medicine, Massachusetts General Hospital, Boston, MA., Dardaei L; Department of Medicine, Massachusetts General Hospital, Boston, MA., Yoda S; Department of Medicine, Massachusetts General Hospital, Boston, MA., Hubbeling H; Department of Medicine, Massachusetts General Hospital, Boston, MA., Digumarthy SR; Department of Radiology, Massachusetts General Hospital, Boston, MA., Riester M; Novartis Institutes of BioMedical Research, Cambridge, MA., Hata AN; Department of Medicine, Massachusetts General Hospital, Boston, MA., Sequist LV; Department of Medicine, Massachusetts General Hospital, Boston, MA., Lennes IT; Department of Medicine, Massachusetts General Hospital, Boston, MA., Iafrate AJ; Department of Pathology, Massachusetts General Hospital, Boston, MA., Heist RS; Department of Medicine, Massachusetts General Hospital, Boston, MA., Azzoli CG; Department of Medicine, Massachusetts General Hospital, Boston, MA., Farago AF; Department of Medicine, Massachusetts General Hospital, Boston, MA., Engelman JA; Novartis Institutes of BioMedical Research, Cambridge, MA., Lennerz JK; Department of Pathology, Massachusetts General Hospital, Boston, MA., Benes CH; Department of Medicine, Massachusetts General Hospital, Boston, MA., Leary RJ; Novartis Institutes of BioMedical Research, Cambridge, MA., Shaw AT; Department of Medicine, Massachusetts General Hospital, Boston, MA., Gainor JF; Department of Medicine, Massachusetts General Hospital, Boston, MA.

المصدر: JCO precision oncology [JCO Precis Oncol] 2018; Vol. 2018. Date of Electronic Publication: 2018 Jan 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2473-4284 (Print) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: PubMed not MEDLINE

المؤلفون: Gao H; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Korn JM; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Ferretti S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Monahan JE; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Wang Y; China Novartis Institutes for Biomedical Research, Shanghai, China., Singh M; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Zhang C; China Novartis Institutes for Biomedical Research, Shanghai, China., Schnell C; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Yang G; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Zhang Y; China Novartis Institutes for Biomedical Research, Shanghai, China., Balbin OA; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Barbe S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Cai H; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Casey F; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Chatterjee S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Chiang DY; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Chuai S; China Novartis Institutes for Biomedical Research, Shanghai, China., Cogan SM; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Collins SD; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Dammassa E; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Ebel N; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Embry M; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Green J; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Kauffmann A; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Kowal C; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Leary RJ; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Lehar J; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Liang Y; China Novartis Institutes for Biomedical Research, Shanghai, China., Loo A; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Lorenzana E; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Robert McDonald E 3rd; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., McLaughlin ME; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Merkin J; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Meyer R; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Naylor TL; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Patawaran M; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Reddy A; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Röelli C; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Ruddy DA; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Salangsang F; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Santacroce F; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Singh AP; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Tang Y; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Tinetto W; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Tobler S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Velazquez R; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Venkatesan K; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Von Arx F; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Wang HQ; Department of Oncology Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Wang Z; China Novartis Institutes for Biomedical Research, Shanghai, China., Wiesmann M; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Wyss D; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Xu F; China Novartis Institutes for Biomedical Research, Shanghai, China., Bitter H; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Atadja P; China Novartis Institutes for Biomedical Research, Shanghai, China., Lees E; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Hofmann F; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Li E; China Novartis Institutes for Biomedical Research, Shanghai, China., Keen N; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Cozens R; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Jensen MR; Oncology Disease Area, Novartis Institutes for Biomedical Research, Basel, Switzerland., Pryer NK; Oncology Disease Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA., Williams JA; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA., Sellers WR; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.

المصدر: Nature medicine [Nat Med] 2015 Nov; Vol. 21 (11), pp. 1318-25. Date of Electronic Publication: 2015 Oct 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , High-Throughput Screening Assays/*methods , Neoplasms/*drug therapy , Xenograft Model Antitumor Assays/*methods, Animals ; Breast Neoplasms/drug therapy ; Carcinoma/drug therapy ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Pancreatic Ductal/drug therapy ; Colorectal Neoplasms/drug therapy ; Disease Models, Animal ; Female ; Humans ; Lung Neoplasms/drug therapy ; Melanoma/drug therapy ; Mice ; Neoplasm Transplantation ; Pancreatic Neoplasms/drug therapy ; Reproducibility of Results ; Skin Neoplasms/drug therapy ; Stomach Neoplasms/drug therapy

المؤلفون: Sausen M; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Phallen J; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Adleff V; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Jones S; Personal Genome Diagnostics Inc., Baltimore, Maryland 21224, USA., Leary RJ; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Barrett MT; The Translational Genomics Research Institute, Scottsdale, Arizona 85004, USA.; Mayo Clinic Arizona, Scottsdale, Arizona 85054, USA., Anagnostou V; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Parpart-Li S; Personal Genome Diagnostics Inc., Baltimore, Maryland 21224, USA., Murphy D; Personal Genome Diagnostics Inc., Baltimore, Maryland 21224, USA., Kay Li Q; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Hruban CA; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Scharpf R; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., White JR; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., O'Dwyer PJ; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA., Allen PJ; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, 10065, USA., Eshleman JR; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Thompson CB; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Klimstra DS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA., Linehan DC; School of Medicine and Dentistry, University of Rochester, Rochester, New York, 14642, USA., Maitra A; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Hruban RH; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.; Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA., Diaz LA Jr; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Von Hoff DD; The Translational Genomics Research Institute, Scottsdale, Arizona 85004, USA.; Virginia Piper Cancer Center, Scottsdale Healthcare, Scottsdale, Arizona 85258, USA., Johansen JS; Department of Oncology and Medicine, Herlev Hospital, University of Copenhagen, Copenhagen 2730, Denmark., Drebin JA; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Velculescu VE; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

المصدر: Nature communications [Nat Commun] 2015 Jul 07; Vol. 6, pp. 7686. Date of Electronic Publication: 2015 Jul 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic/*physiology , Pancreatic Neoplasms/*blood , Pancreatic Neoplasms/*genetics, Biomarkers, Tumor ; DNA/blood ; Genomics ; Humans ; Predictive Value of Tests ; Recurrence ; Treatment Outcome