المؤلفون: Neves JLB; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Urcino C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Dowell C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Hone AJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Mental Illness Research Education and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Morgenstern D; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., Chua VM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ramiro IBL; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; The Marine Science Institute, University of the Philippines, Quezon City 1101, Philippines., Imperial JS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Phan J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Fisher FA; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Watkins M; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Tun JO; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ueberheide BM; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., McIntosh JM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA.; Mental Health Department, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Vasconcelos V; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Gajewiak J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

المصدر: Marine drugs [Mar Drugs] 2024 Feb 29; Vol. 22 (3). Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Conus Snail* , Conotoxins* , Receptors, Nicotinic*, Animals ; Mice ; Calcium ; Amino Acid Sequence ; alpha7 Nicotinic Acetylcholine Receptor

المؤلفون: Paguigan ND; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 81112, United States., Yan Y; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Karthikeyan M; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Chase K; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Carter J; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Leavitt LS; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Lim AL; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 81112, United States., Lin Z; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 81112, United States., Memon T; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 81112, United States., Christensen S; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Bentzen BH; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Schmitt N; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Reilly CA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 81112, United States., Teichert RW; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Raghuraman S; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Olivera BM; Department of Biology, University of Utah, Salt Lake City, Utah 81112, United States., Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 81112, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2021 Sep 17; Vol. 16 (9), pp. 1654-1662. Date of Electronic Publication: 2021 Aug 23.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Amines/*metabolism , Calcium Channels/*metabolism , Sensory Receptor Cells/*metabolism, Amines/administration & dosage ; Animals ; Calcium/metabolism ; Ganglia, Spinal/metabolism ; Male ; Mice ; Patch-Clamp Techniques ; Signal Transduction ; Thermosensing/physiology ; Urochordata ; Vertebrates

المؤلفون: Paguigan ND; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Tun JO; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Lin Z; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Dowell C; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Deering-Rice CE; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Lim AL; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Karthikeyan M; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Hughen RW; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Zhang J; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Peterson RT; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Reilly CA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Light AR; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., McIntosh JM; Department of Psychiatry, and School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.; George E Whalen Veterans Affairs Medical Center, Salt Lake City, Utah 84148, United States., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jul 21; Vol. 12 (14), pp. 2693-2704. Date of Electronic Publication: 2021 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Nicotinic* , Urochordata*, Animals ; Aplysia ; Mice ; Nicotinic Antagonists/pharmacology ; Nylons ; Rats ; alpha7 Nicotinic Acetylcholine Receptor

المؤلفون: Niu C; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Lin Z; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Paguigan ND; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Sun L; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Zhang J; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Torres JP; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Cadeddu R; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Karthikeyan M; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Bortolato M; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Reilly CA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States., Hughen RW; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Light AR; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 May 27; Vol. 64 (10), pp. 7033-7043. Date of Electronic Publication: 2021 May 05.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Analgesics/*chemistry , Conus Snail/*chemistry , GABA Antagonists/*chemistry , Neurosteroids/*chemistry , Receptors, GABA/*chemistry, Action Potentials/drug effects ; Analgesics/chemical synthesis ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Animals ; Conus Snail/metabolism ; Disease Models, Animal ; GABA Antagonists/isolation & purification ; GABA Antagonists/pharmacology ; GABA Antagonists/therapeutic use ; Ganglia, Spinal/cytology ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/physiology ; Mice ; Mice, Inbred C57BL ; Molecular Conformation ; Neurosteroids/isolation & purification ; Neurosteroids/pharmacology ; Neurosteroids/therapeutic use ; Pain/chemically induced ; Pain/drug therapy ; Pain/pathology ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Receptors, GABA/metabolism

المؤلفون: Giacobassi MJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Alluri R; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Finol-Urdaneta RK; Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia., Terlau H; Institute of Physiology, Christian Albrechts University Kiel, Kiel 24118, Germany., Teichert RW; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, UT 841120; olivera@biology.utah.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Mar 10; Vol. 117 (10), pp. 5494-5501. Date of Electronic Publication: 2020 Feb 20.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Ganglia, Spinal/*cytology , Sensory Receptor Cells/*classification , Sensory Receptor Cells/*physiology, Animals ; Calcium/metabolism ; Conotoxins/pharmacology ; Cytosol/metabolism ; Ganglia, Spinal/drug effects ; Kv1.1 Potassium Channel/antagonists & inhibitors ; Mice ; Mice, Transgenic ; Peptides/pharmacology ; Potassium Channel Blockers/pharmacology ; Sensory Receptor Cells/drug effects ; Single-Cell Analysis ; Transcriptome

المؤلفون: Cordeiro S; Institute of Physiology, Christian-Albrechts-University Kiel, 24118 Kiel, Germany., Finol-Urdaneta RK; Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.; Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 4N1, Canada., Köpfer D; Max-Planck-Institute for Biophysical Chemistry, Computational Biomolecular Dynamics Group, 37077 Göttingen, Germany., Markushina A; Institute of Physiology, Christian-Albrechts-University Kiel, 24118 Kiel, Germany., Song J; Institute of Physiology, Christian-Albrechts-University Kiel, 24118 Kiel, Germany., French RJ; Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 4N1, Canada., Kopec W; Max-Planck-Institute for Biophysical Chemistry, Computational Biomolecular Dynamics Group, 37077 Göttingen, Germany., de Groot BL; Max-Planck-Institute for Biophysical Chemistry, Computational Biomolecular Dynamics Group, 37077 Göttingen, Germany., Giacobassi MJ; Department of Biology, University of Utah, Salt Lake City, UT 841120., Leavitt LS; Department of Biology, University of Utah, Salt Lake City, UT 841120., Raghuraman S; Department of Biology, University of Utah, Salt Lake City, UT 841120., Teichert RW; Department of Biology, University of Utah, Salt Lake City, UT 841120., Olivera BM; Department of Biology, University of Utah, Salt Lake City, UT 841120 olivera@biology.utah.edu h.terlau@physiologie.uni-kiel.de., Terlau H; Institute of Physiology, Christian-Albrechts-University Kiel, 24118 Kiel, Germany; olivera@biology.utah.edu h.terlau@physiologie.uni-kiel.de.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jan 15; Vol. 116 (3), pp. 1059-1064. Date of Electronic Publication: 2018 Dec 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Conotoxins*/chemistry , Conotoxins*/metabolism , Ganglia, Spinal*/chemistry , Ganglia, Spinal*/metabolism , Membrane Potentials* , Molecular Dynamics Simulation* , Neurons*/chemistry , Neurons*/metabolism , Shaker Superfamily of Potassium Channels*/antagonists & inhibitors , Shaker Superfamily of Potassium Channels*/chemistry , Shaker Superfamily of Potassium Channels*/metabolism, HEK293 Cells ; Humans ; Ion Transport ; Protein Binding

المؤلفون: Memon T; Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, United States., Chase K; Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, United States., Leavitt LS; Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, United States., Olivera BM; Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, United States., Teichert RW; Department of Biology, University of Utah, 257 S. 1400 E., Salt Lake City, UT 84112, United States. Electronic address: russ.teichert@utah.edu.

المصدر: Neuroscience [Neuroscience] 2017 Jun 14; Vol. 353, pp. 76-86. Date of Electronic Publication: 2017 Apr 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

مواضيع طبية MeSH: Cold Temperature* , Thermosensing*, Ganglia, Spinal/*physiology , Neurons/*physiology , Nociception/*physiology , Potassium Channels, Voltage-Gated/*physiology , TRPA1 Cation Channel/*physiology , Thermoreceptors/*physiology, Animals ; Cells, Cultured ; Female ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; HEK293 Cells ; Humans ; Isothiocyanates/administration & dosage ; Male ; Menthol/administration & dosage ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/drug effects ; Neurons/metabolism ; Potassium Channels, Voltage-Gated/antagonists & inhibitors ; TRPA1 Cation Channel/genetics ; TRPA1 Cation Channel/metabolism ; TRPM Cation Channels/genetics ; TRPM Cation Channels/metabolism ; TRPM Cation Channels/physiology

المؤلفون: Furlong TM; Department of Pharmacology and Toxicology, University of Utah, 30 S. 2000 E., Rm 201, Salt Lake City, UT, 84112, USA. teri.furlong@utah.edu., Leavitt LS; Department of Pharmacology and Toxicology, University of Utah, 30 S. 2000 E., Rm 201, Salt Lake City, UT, 84112, USA., Keefe KA; Department of Pharmacology and Toxicology, University of Utah, 30 S. 2000 E., Rm 201, Salt Lake City, UT, 84112, USA., Son JH; Department of Pharmacology and Toxicology, University of Utah, 30 S. 2000 E., Rm 201, Salt Lake City, UT, 84112, USA.

المصدر: Neurotoxicity research [Neurotox Res] 2016 May; Vol. 29 (4), pp. 569-82. Date of Electronic Publication: 2016 Feb 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-3524 (Electronic) Linking ISSN: 10298428 NLM ISO Abbreviation: Neurotox Res Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*drug effects , Central Nervous System Stimulants/*toxicity , Dopamine Plasma Membrane Transport Proteins/*metabolism , Impulsive Behavior/*drug effects , Neurotoxicity Syndromes/*etiology , Neurotoxicity Syndromes/*physiopathology, Animals ; Body Temperature/drug effects ; Brain/metabolism ; Dextroamphetamine ; Disease Models, Animal ; Dopamine/metabolism ; Male ; Methamphetamine ; Motor Activity/drug effects ; Neuropsychological Tests ; Rats ; Rats, Sprague-Dawley ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins ; Time Factors ; p-Chloroamphetamine

المؤلفون: Curtice KJ; Department of Biology, University of Utah, Salt Lake City, Utah., Leavitt LS; Department of Biology, University of Utah, Salt Lake City, Utah., Chase K; Department of Biology, University of Utah, Salt Lake City, Utah., Raghuraman S; Department of Biology, University of Utah, Salt Lake City, Utah., Horvath MP; Department of Biology, University of Utah, Salt Lake City, Utah., Olivera BM; Department of Biology, University of Utah, Salt Lake City, Utah., Teichert RW; Department of Biology, University of Utah, Salt Lake City, Utah russ.teichert@utah.edu.

المصدر: Journal of neurophysiology [J Neurophysiol] 2016 Feb 01; Vol. 115 (2), pp. 1031-42. Date of Electronic Publication: 2015 Nov 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

مواضيع طبية MeSH: Cerebellum/*cytology , Neuroglia/*classification , Neurons/*classification, Action Potentials ; Animals ; Cells, Cultured ; Ion Channels/antagonists & inhibitors ; Ion Channels/classification ; Mice ; Mice, Inbred C57BL ; Neuroglia/metabolism ; Neuroglia/physiology ; Neurons/metabolism ; Neurons/physiology ; Receptors, Neurotransmitter/agonists ; Receptors, Neurotransmitter/antagonists & inhibitors ; Receptors, Neurotransmitter/classification