المؤلفون: Ileana Corvo, Florencia Ferraro, Alicia Merlino, Kathrin Zuberbühler, Anthony J. O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Tatiana Basika, Leda Roche, James H. McKerrow, Charles S. Craik, Conor R. Caffrey, José F. Tort

المصدر: Frontiers in Molecular Biosciences, Vol 5 (2018)

مصطلحات موضوعية: Fasciola hepatica, cathepsin L, active site conformation, S2 pocket, mutagenesis, molecular dynamics simulation, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fmolb.2018.00040/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/d4c2423d90c340b9bc971306ed846e6a

المؤلفون: Ileana Corvo, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Alegra Eroy-Reveles, Leda Roche, James H McKerrow, John P Dalton, Charles S Craik, Conor R Caffrey, José F Tort

المصدر: PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2269 (2013)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3708847?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/39e3cf915bba40f283c68f81e3d26e2e

المؤلفون: Mark W Robinson, Ileana Corvo, Peter M Jones, Anthony M George, Matthew P Padula, Joyce To, Martin Cancela, Gabriel Rinaldi, Jose F Tort, Leda Roche, John P Dalton

المصدر: PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1012 (2011)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3071364?pdf=render; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/0d9f9991408b4538968d958192283b3b

المؤلفون: Víctor Raggio, Leda Roche

المصدر: Revista Médica del Uruguay, Vol 25, Iss 1 (2009)

مصطلحات موضوعية: BIOLOGÍA MOLECULAR, GENOMA HUMANO, GENÉTICA MEDICA, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://revista.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/478; https://doaj.org/toc/0303-3295; https://doaj.org/toc/1688-0390

URL الوصول: https://doaj.org/article/088a9e899e404647912c3d57c7e7065a

المؤلفون: Víctor Raggio, Leda Roche, Patricia Esperón, Mario Stoll

المصدر: Revista Médica del Uruguay, Vol 23, Iss 2 (2007)

مصطلحات موضوعية: EDUCACION MEDICA CONTINUA, EDUCACION A DISTANCIA, TECNOLOGIA EDUCACIONAL GENOMICA, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://revista.rmu.org.uy/ojsrmu311/index.php/rmu/article/view/626; https://doaj.org/toc/0303-3295; https://doaj.org/toc/1688-0390

URL الوصول: https://doaj.org/article/3a976efd905a4055b3358bc12a50ae65

المؤلفون: Alvaro Díaz, Martín Cancela, Arnaldo Zaha, Edileuza Danieli da Silva, Henrique Bunselmeyer Ferreira, Ileana Corvo, Leda Roche, Aline Teichmann, José Fransisco Tort

المصدر: Parasitology. 144:1695-1707

مصطلحات موضوعية: 0301 basic medicine, Signal peptide, Cathepsin L, Cysteine Proteinase Inhibitors, Cathepsin C, Cathepsin B, 03 medical and health sciences, Hepatica, parasitic diseases, Escherichia coli, Animals, Humans, Fasciola hepatica, Amino Acid Sequence, Phylogeny, Organisms, Genetically Modified, biology, Helminth Proteins, biology.organism_classification, Cystatins, Recombinant Proteins, 030104 developmental biology, Infectious Diseases, Biochemistry, biology.protein, Cattle, Animal Science and Zoology, Parasitology, Cystatin, Sequence Alignment, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d833c6fddfe1d769aa91517d9e80265
https://doi.org/10.1017/s0031182017001093

المؤلفون: Natalia Pi-Denis, Lucía Pastro, Gabriel Peluffo, Nicolás Curbelo, Alejandra Vomero, Leda Roche, María Boidi, Víctor Raggio, Martin Ciganda, Alejandra Tapié, Jorge Souto

المساهمون: Tapie, Alejandra. Universidad de la República (Uruguay). Facultad de Medicina, Pi-Denis, Natalia. Universidad de la República (Uruguay). Facultad de Medicina, Souto, Jorge. Universidad de la República (Uruguay). Facultad de Medicina, Vomero, Alejandra. Universidad de la República (Uruguay). Facultad de Medicina, Peluffo, Gabriel. Universidad de la República (Uruguay). Facultad de Medicina, Boidi, María. Universidad de la República (Uruguay). Facultad de Medicina, Ciganda, Martín. Universidad de la República (Uruguay). Facultad de Ciencias. Laboratorio de Interacciones Moleculares, Curbelo, Nicolás. Universidad de la República (Uruguay). Facultad de Medicina, Raggio, Victor. Universidad de la República (Uruguay). Facultad de Medicina, Roche, Leda. Universidad de la República (Uruguay). Facultad de Medicina, Pastro, Lucía. Universidad de la República (Uruguay). Facultad de Ciencias. Laboratorio de Interacciones Moleculares

المصدر: COLIBRI
Universidad de la República
instacron:Universidad de la República
Clinical Case Reports

مصطلحات موضوعية: 0301 basic medicine, Ohtahara syndrome, Case Report, Case Reports, 030105 genetics & heredity, mental retardation, Domain (software engineering), 03 medical and health sciences, Epilepsy, 0302 clinical medicine, medicine, Missense mutation, In patient, Gene, Genetics, business.industry, Mental retardation, General Medicine, medicine.disease, Molecular analysis, epilepsy, ARX, business, Novel mutation, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc103ecb6c53bff4b71e56c98c86f11
https://doi.org/10.1002/ccr3.769

المؤلفون: Conor R. Caffrey, Alicia Merlino, José F. Tort, Leda Roche, Lucía Pastro, James H. McKerrow, Ileana Corvo, Kathrin Zuberbühler, Tatiana Basika, Anthony J. O’Donoghue, Charles S. Craik, Florencia Ferraro, Natalia Pi-Denis

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 5 (2018)

مصطلحات موضوعية: 0301 basic medicine, Proteases, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, cathepsin L, Cathepsin L, 03 medical and health sciences, active site conformation, Molecular Biosciences, lcsh:QH301-705.5, Molecular Biology, Original Research, chemistry.chemical_classification, S2 pocket, 030102 biochemistry & molecular biology, biology, Tissue migration, Active site, Substrate (chemistry), Fasciola hepatica, Amino acid, 030104 developmental biology, Enzyme, molecular dynamics simulation, lcsh:Biology (General), chemistry, biology.protein, mutagenesis, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819b246a53aead9a5b748f9b02846ca0
http://europepmc.org/articles/PMC5917446

المؤلفون: Gabriela Maggioli, Daniel Acosta, Tatiana Basika, Diego Rosadilla, José F. Tort, Valeria Gayo, Fernando Silveira, Leda Roche, Silvina Rossi, Sheila Giacaman, Carlos Carmona

المصدر: Vaccine. 29:9057-9063

مصطلحات موضوعية: Male, Fascioliasis, medicine.medical_treatment, Antibodies, Helminth, Sheep Diseases, Parasite Load, Microbiology, Leucyl Aminopeptidase, chemistry.chemical_compound, Adjuvants, Immunologic, Hepatica, parasitic diseases, medicine, Animals, Fasciola hepatica, Sheep, Domestic, Vaccines, Sheep, General Veterinary, General Immunology and Microbiology, biology, Alum, Vaccination, Public Health, Environmental and Occupational Health, Liver fluke, biology.organism_classification, Virology, Recombinant Proteins, Infectious Diseases, chemistry, Immunoglobulin G, Antibody Formation, biology.protein, Molecular Medicine, Antibody, Leucine, Adjuvant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6beb29393889cb192cfc156c4c916801
https://doi.org/10.1016/j.vaccine.2011.09.020

المؤلفون: Mónica Cappetta, Leda Roche, Natalia Pi-Denis, Martín Cancela, José F. Tort, Ileana Corvo

المصدر: Molecular and Biochemical Parasitology. 167:41-47

مصطلحات موضوعية: Models, Molecular, Cathepsin L, Molecular Sequence Data, Gene Expression, Cathepsin A, Pichia, Cathepsin O, Catalytic Domain, Enzyme Stability, Cathepsin K, medicine, Animals, Molecular Biology, Cathepsin, biology, Temperature, Active site, Sequence Analysis, DNA, DNA, Helminth, Fasciola hepatica, Hydrogen-Ion Concentration, Cathepsins, Protein Structure, Tertiary, Cysteine Endopeptidases, Biochemistry, biology.protein, Collagenase, Parasitology, Collagen, Type I collagen, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17702ba87b6c4d46a467d41c3f2a5784
https://doi.org/10.1016/j.molbiopara.2009.04.005