المؤلفون: Badran YR; Division of Gastroenterology, Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, MA, USA., Zou F; Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China., Durbin SM; Harvard Medical School, Boston, MA, USA.; Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Dutra BE; Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Abu-Sbeih H; Department of Internal Medicine, University of Missouri Kansas City, Kansas City, Missouri, USA., Thomas AS; Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Altan M; Department of Thoracic, Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Thompson JA; Department of Medicine, Division of Oncology, Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance, University of Washington, Seattle, Washington, USA., Qiao W; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Leet DE; Harvard Medical School, Boston, MA, USA.; Department of Internal Medicine, University of California San Francisco, San Francisco, California, USA., Lai PY; Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA., Horick NK; Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA., Postow MA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Medicine, Weill Cornell Medical Center, New York, New York, USA., Faleck DM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA mldougan@partners.org YWang59@mdanderson.org faleckd@mskcc.org.; Department of Medicine, Weill Cornell Medical Center, New York, New York, USA., Wang Y; Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA mldougan@partners.org YWang59@mdanderson.org faleckd@mskcc.org., Dougan M; Division of Gastroenterology, Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA mldougan@partners.org YWang59@mdanderson.org faleckd@mskcc.org.; Harvard Medical School, Boston, MA, USA.

المصدر: Journal for immunotherapy of cancer [J Immunother Cancer] 2023 Jun; Vol. 11 (6).

نوع المنشور: Multicenter Study; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Immunological*/adverse effects , Enterocolitis*/drug therapy, Humans ; Immune Checkpoint Inhibitors/adverse effects ; Infliximab/therapeutic use ; Retrospective Studies ; Immunosuppression Therapy

المؤلفون: Hu Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Leet DE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Allesøe RL; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Oliveira G; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Li S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Luoma AM; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Liu J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA., Forman J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Huang T; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Iorgulescu JB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Holden R; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Sarkizova S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gohil SH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Academic Haematology, University College London, London, UK., Redd RA; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA., Sun J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Elagina L; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Giobbie-Hurder A; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA., Zhang W; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Peter L; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA., Ciantra Z; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Rodig S; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Olive O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Shetty K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Pyrdol J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Uduman M; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Lee PC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Bachireddy P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Buchbinder EI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Yoon CH; Harvard Medical School, Boston, MA, USA.; Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA., Neuberg D; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA., Pentelute BL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Hacohen N; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA., Livak KJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Olsen LR; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Lyngby, Denmark.; Center for Genomic Medicine, Copenhagen University Hospital, Copenhagan, Denmark., Barouch DH; Harvard Medical School, Boston, MA, USA.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Wucherpfennig KW; Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Fritsch EF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Ott PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. patrick_ott@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. patrick_ott@dfci.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. patrick_ott@dfci.harvard.edu.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. patrick_ott@dfci.harvard.edu.

المصدر: Nature medicine [Nat Med] 2021 Mar; Vol. 27 (3), pp. 515-525. Date of Electronic Publication: 2021 Jan 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Immunologic Memory*, Antigens, Neoplasm/*genetics , Cancer Vaccines/*immunology , Epitopes/*immunology , Melanoma/*immunology, Humans ; Melanoma/pathology

المؤلفون: Thompson LL; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Katznelson E; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Leet DE; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Durbin SM; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Yoon J; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Reynolds KL; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Dougan ML; Department of Medicine, Division of Gastroenterology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA., Chen ST; Department of Medicine, Division of Hematology & Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA; Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: stchen@partners.org.

المصدر: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 Jan; Vol. 142, pp. 143-146. Date of Electronic Publication: 2020 Oct 22.

نوع المنشور: Letter

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Adrenal Cortex Hormones/*therapeutic use , Colitis/*chemically induced , Colitis/*drug therapy , Immune Checkpoint Inhibitors/*adverse effects, Adrenal Cortex Hormones/pharmacology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome

المؤلفون: Badran YR; Department of Medicine, Massachusetts General Hospital , Boston, MA, USA.; Medical Student, Harvard Medical School , Boston, MA, USA., Leet DE; Medical Student, Harvard Medical School , Boston, MA, USA., Dougan M; Medical Student, Harvard Medical School , Boston, MA, USA.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital , Boston, MA, USA.

المصدر: Expert review of anticancer therapy [Expert Rev Anticancer Ther] 2020 Sep; Vol. 20 (9), pp. 727-730. Date of Electronic Publication: 2020 Sep 01.

نوع المنشور: Editorial

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101123358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8328 (Electronic) Linking ISSN: 14737140 NLM ISO Abbreviation: Expert Rev Anticancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Immune Checkpoint Inhibitors/*adverse effects , Immunotherapy/*adverse effects , Neoplasms/*therapy, Animals ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immunotherapy/methods ; Neoplasms/immunology

المؤلفون: Hu Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Anandappa AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Sun J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Kim J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Leet DE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Bozym DJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA., Chen C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Williams L; Broad Institute of MIT and Harvard, Cambridge, MA., Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA., Zhang W; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Tabbaa D; Broad Institute of MIT and Harvard, Cambridge, MA., Steelman S; Broad Institute of MIT and Harvard, Cambridge, MA., Olive O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Livak KJ; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA., Kishi H; Department of Immunology, University of Toyama, Toyama, Japan., Muraguchi A; Department of Immunology, University of Toyama, Toyama, Japan., Guleria I; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Stevens J; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Lane WJ; Harvard Medical School, Boston, MA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Burkhardt UE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Fritsch EF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA., Neuberg D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA., Ott PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and., Hacohen N; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Massachusetts General Hospital, Boston, MA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.; Harvard Medical School, Boston, MA.; Broad Institute of MIT and Harvard, Cambridge, MA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA; and.

المصدر: Blood [Blood] 2018 Nov 01; Vol. 132 (18), pp. 1911-1921. Date of Electronic Publication: 2018 Aug 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood

مواضيع طبية MeSH: T-Cell Antigen Receptor Specificity*, Antigens, Neoplasm/*immunology , Receptors, Antigen, T-Cell/*immunology, Cancer Vaccines/therapeutic use ; Cells, Cultured ; Cloning, Molecular/methods ; HEK293 Cells ; Humans ; Jurkat Cells ; Leukemia, Lymphocytic, Chronic, B-Cell/immunology ; Melanoma/immunology ; Melanoma/therapy ; Receptors, Antigen, T-Cell/genetics

المؤلفون: Agarwal I; Department of Biology, Amherst College, Massachusetts 01002., Farnow C; Department of Biology, Amherst College, Massachusetts 01002., Jiang J; Program in Biochemistry and Biophysics, Amherst College, Massachusetts 01002., Kim KS; Department of Biology, Amherst College, Massachusetts 01002., Leet DE; Department of Biology, Amherst College, Massachusetts 01002., Solomon RZ; Department of Biology, Amherst College, Massachusetts 01002., Hale VA; Department of Biology, Amherst College, Massachusetts 01002., Goutte C; Department of Biology, Amherst College, Massachusetts 01002 cegoutte@amherst.edu.; Program in Biochemistry and Biophysics, Amherst College, Massachusetts 01002.

المصدر: Genetics [Genetics] 2018 Feb; Vol. 208 (2), pp. 745-762. Date of Electronic Publication: 2017 Dec 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-2631 (Electronic) Linking ISSN: 00166731 NLM ISO Abbreviation: Genetics Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Caenorhabditis elegans/*genetics , Germ Cells/*metabolism , Membrane Proteins/*deficiency , Receptors, Notch/*metabolism, Alleles ; Animals ; Caenorhabditis elegans Proteins ; Cell Proliferation ; Gain of Function Mutation ; Glucagon-Like Peptide-1 Receptor/metabolism ; Gonads/metabolism ; Male ; Mutation ; Oocytes/metabolism ; Oogenesis ; Phenotype ; Reproduction/genetics