المؤلفون: Brett T. Wisniewski, Jane E. Dorweiler, Legan Er, Davis Ee, Anita L. Manogaran, Douglas R. Lyke

مصطلحات موضوعية: 0303 health sciences, Cell division, biology, animal diseases, 030302 biochemistry & molecular biology, Mutant, Actin remodeling, Arp2/3 complex, macromolecular substances, Yeast, nervous system diseases, Cell biology, 03 medical and health sciences, Fimbrin, biology.protein, MDia1, Actin, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5984572c6405637f127c6f81fd4cfa
https://doi.org/10.1101/145060

المؤلفون: Arce NA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Markham-Lee Z; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Liang Q; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Najmudin S; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Dean G; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Su AJ; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Wilson MS; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Sidonio RF; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Lollar P; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA., Emsley J; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.

المصدر: Blood [Blood] 2024 May 09; Vol. 143 (19), pp. 1992-2004.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor*/metabolism , von Willebrand Factor*/chemistry , Single-Domain Antibodies*/pharmacology , Single-Domain Antibodies*/chemistry , Single-Domain Antibodies*/metabolism, Humans ; Platelet Aggregation/drug effects ; Protein Conformation ; Protein Domains ; Protein Binding ; Platelet Adhesiveness/drug effects ; Crystallography, X-Ray ; Animals ; Blood Platelets/metabolism

المؤلفون: Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA., Liu Y; Department of Bioengineering, Lehigh University, Bethlehem, PA.; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA., Arce NA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA., Parker ET; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA., Lollar P; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA., Zhang XF; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA., Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA.

المصدر: Blood [Blood] 2023 Mar 09; Vol. 141 (10), pp. 1221-1232.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Disease, Type 2*/genetics , von Willebrand Factor*/chemistry , von Willebrand Factor*/genetics , von Willebrand Factor*/metabolism, Humans ; Binding Sites ; Blood Platelets/metabolism ; Mutation ; Platelet Glycoprotein GPIb-IX Complex/metabolism

المؤلفون: Dorweiler JE; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Lyke DR; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Lemoine NP; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA.; Department of Zoology, Milwaukee Public Museum, Milwaukee, WI 53233, USA., Guereca S; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Buchholz HE; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Legan ER; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Radtke CM; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA., Manogaran AL; Department of Biological Sciences, Marquette University, Milwaukee, WI 53233, USA.

المصدر: Viruses [Viruses] 2022 Jul 21; Vol. 14 (7). Date of Electronic Publication: 2022 Jul 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Prions*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae Proteins*/metabolism, Actin Cytoskeleton/metabolism ; Actins/metabolism ; Peptide Termination Factors/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism

المؤلفون: Ito J; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Baldwin WH; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Cox C; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Healey JF; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Parker ET; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Legan ER; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Li R; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Gill S; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Batsuli G; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, Georgia, USA.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Mar; Vol. 20 (3), pp. 574-588. Date of Electronic Publication: 2021 Dec 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Factor VIII* , Hemophilia A*, Animals ; Antibodies, Monoclonal ; Mice ; Polysaccharides ; von Willebrand Factor/metabolism

المؤلفون: Voos KM; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA., Cao W; Department of Bioengineering, Lehigh University, Bethlehem, Pennsylvania, USA., Arce NA; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA., Legan ER; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA., Wang Y; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA., Shajahan A; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Azadi P; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Lollar P; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA., Zhang XF; Department of Bioengineering, Lehigh University, Bethlehem, Pennsylvania, USA., Li R; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, Georgia, USA.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Jan; Vol. 20 (1), pp. 196-207. Date of Electronic Publication: 2021 Sep 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Disease, Type 2*/metabolism , von Willebrand Factor*/metabolism, Animals ; Blood Platelets/metabolism ; Platelet Aggregation ; Platelet Glycoprotein GPIb-IX Complex/metabolism ; Polysaccharides ; Protein Binding

المؤلفون: Arce NA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Cao W; Department of Bioengineering, Department of Mechanical Engineering & Mechanics, Lehigh University, Bethlehem, PA, USA., Brown AK; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK., Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Wilson MS; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Xu ER; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK., Berndt MC; Faculty of Health Sciences, Curtin University, Perth, WA, Australia., Emsley J; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK., Zhang XF; Department of Bioengineering, Department of Mechanical Engineering & Mechanics, Lehigh University, Bethlehem, PA, USA. xiz310@lehigh.edu., Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA. renhao.li@emory.edu.

المصدر: Nature communications [Nat Commun] 2021 Apr 21; Vol. 12 (1), pp. 2360. Date of Electronic Publication: 2021 Apr 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: von Willebrand Factor/*chemistry , von Willebrand Factor/*metabolism, Antibodies, Monoclonal/pharmacology ; Biomechanical Phenomena ; Crystallography, X-Ray ; Humans ; In Vitro Techniques ; Models, Molecular ; Mutation ; Platelet Aggregation/drug effects ; Protein Conformation ; Protein Domains ; Protein Stability ; Protein Unfolding ; Ristocetin/pharmacology ; Single Molecule Imaging ; Single-Domain Antibodies/pharmacology ; Tensile Strength ; von Willebrand Factor/genetics

المؤلفون: Legan ER; From the Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, GA., Li R; From the Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, GA.

المصدر: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2019 Sep; Vol. 39 (9), pp. 1702-1704. Date of Electronic Publication: 2019 Aug 21.

نوع المنشور: Editorial; Research Support, N.I.H., Extramural; Comment

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

مواضيع طبية MeSH: Thrombospondins* , von Willebrand Factor*, Disintegrins ; Metalloproteases ; Thrombospondin 1

المؤلفون: Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia., Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2019 Jun; Vol. 17 (6), pp. 863-865.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Factor VIII* , von Willebrand Factor*, Blood Coagulation Tests ; Phosphorylation ; Platelet Adhesiveness

المؤلفون: Deng W; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Voos KM; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Colucci JK; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Legan ER; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Lollar P; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Li R; Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2018 Oct; Vol. 16 (10), pp. 2097-2105. Date of Electronic Publication: 2018 Aug 16.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Hemostasis*, Peptide Fragments/*metabolism , von Willebrand Factor/*metabolism, Blood Platelets/metabolism ; Humans ; Mechanotransduction, Cellular ; Peptide Fragments/chemistry ; Platelet Glycoprotein GPIb-IX Complex/metabolism ; Protein Interaction Domains and Motifs ; Protein Stability ; Transition Temperature ; von Willebrand Factor/chemistry