المؤلفون: Ballet, C, Correia, MSP, Conway, LP, Locher, TL, Lehmann, LC, Garg, N, Vujasinovic, M, Deindl, S, Lohr, JM, Globisch, D

المصدر: Chemical science. 9(29):6233-6239

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:138767282

المؤلفون: Bacic L; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Gaullier G; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Sabantsev A; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Brackmann K; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Dimakou D; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Halic M; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, United States., Hewitt G; The Francis Crick Institute, London, United Kingdom., Boulton SJ; The Francis Crick Institute, London, United Kingdom., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

المصدر: ELife [Elife] 2021 Sep 06; Vol. 10. Date of Electronic Publication: 2021 Sep 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin Assembly and Disassembly* , Poly ADP Ribosylation*, Carrier Proteins/*metabolism , DNA Helicases/*metabolism , DNA-Binding Proteins/*metabolism , Nuclear Proteins/*metabolism , Nucleosomes/*metabolism , Poly (ADP-Ribose) Polymerase-1/*metabolism , Poly(ADP-ribose) Polymerases/*metabolism, Carrier Proteins/genetics ; Cryoelectron Microscopy ; DNA Helicases/genetics ; DNA Helicases/ultrastructure ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/ultrastructure ; Humans ; Kinetics ; Models, Molecular ; Nuclear Proteins/genetics ; Nucleosomes/genetics ; Nucleosomes/ultrastructure ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly(ADP-ribose) Polymerases/genetics ; Protein Binding ; Protein Conformation ; Recombinant Proteins/metabolism ; Structure-Activity Relationship ; Substrate Specificity

المؤلفون: Hewitt G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Borel V; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Segura-Bayona S; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Takaki T; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Ruis P; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Bellelli R; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Sommerova L; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Vancevska A; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Tomas-Loba A; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Zhu K; Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK., Cooper C; Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK., Fugger K; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Patel H; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Goldstone R; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Schneider-Luftman D; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Herbert E; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Stamp G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Brough R; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Pettitt S; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Lord CJ; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., West SC; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Ahel I; Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK., Ahel D; Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK., Chapman JR; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Boulton SJ; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Artios Pharma Ltd., Meditrina, Babraham Research Campus, Cambridge CB22 3AT, UK. Electronic address: simon.boulton@crick.ac.uk.

المصدر: Molecular cell [Mol Cell] 2021 Feb 18; Vol. 81 (4), pp. 767-783.e11. Date of Electronic Publication: 2020 Dec 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin Assembly and Disassembly*, DNA Helicases/*metabolism , DNA-Binding Proteins/*metabolism , Neoplasm Proteins/*metabolism , Neoplasms, Experimental/*metabolism , Nucleosomes/*metabolism , Poly(ADP-ribose) Polymerases/*metabolism, Animals ; DNA Helicases/genetics ; DNA Replication/drug effects ; DNA-(Apurinic or Apyrimidinic Site) Lyase/genetics ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; DNA-Binding Proteins/genetics ; Homologous Recombination/drug effects ; Mice ; Mice, Knockout ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/genetics ; Neoplasms, Experimental/genetics ; Nucleosomes/genetics ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerases/genetics

المؤلفون: Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Bacic L; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Hewitt G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Brackmann K; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Sabantsev A; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Gaullier G; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Pytharopoulou S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Degliesposti G; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK., Okkenhaug H; Imaging Facility, Babraham Institute, Cambridge CB22 3AT, UK., Tan S; Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA., Costa A; Macromolecular Machines Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Skehel JM; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK., Boulton SJ; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: simon.boulton@crick.ac.uk., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden. Electronic address: sebastian.deindl@icm.uu.se.

المصدر: Cell reports [Cell Rep] 2020 Dec 22; Vol. 33 (12), pp. 108529.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage*, DNA Helicases/*metabolism , DNA-Binding Proteins/*metabolism , Nucleosomes/*metabolism, Animals ; Histones/metabolism ; Humans ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Xenopus laevis

المؤلفون: Marklund E; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., van Oosten B; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Mao G; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Amselem E; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Kipper K; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Sabantsev A; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Emmerich A; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Globisch D; Department of Medicinal Chemistry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Zheng X; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Berg OG; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Johansson M; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Elf J; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. johan.elf@icm.uu.se., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. sebastian.deindl@icm.uu.se.

المصدر: Nature [Nature] 2020 Jul; Vol. 583 (7818), pp. 858-861. Date of Electronic Publication: 2020 Jun 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Nucleic Acid Conformation* , Substrate Specificity*/genetics, DNA/*chemistry , Operator Regions, Genetic/*genetics, Binding Sites/genetics ; DNA/genetics ; Diffusion ; Fluorescence Resonance Energy Transfer ; Kinetics ; Lac Repressors/metabolism ; Protein Binding ; Rotation ; Single Molecule Imaging ; Spectrometry, Fluorescence

المؤلفون: Kipper K; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Eremina N; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Marklund E; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Tubasum S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Mao G; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Elf J; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

المصدر: PloS one [PLoS One] 2018 Jun 01; Vol. 13 (6), pp. e0198416. Date of Electronic Publication: 2018 Jun 01 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Escherichia coli/*metabolism , Escherichia coli Proteins/*genetics , Fluorescent Dyes/*chemistry , Lac Repressors/*genetics, Binding Sites ; Dimerization ; Electrophoretic Mobility Shift Assay ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/metabolism ; Immobilized Nucleic Acids/chemistry ; Immobilized Nucleic Acids/metabolism ; Lac Repressors/chemistry ; Lac Repressors/metabolism ; Maleimides/chemistry ; Microscopy, Fluorescence ; Mutagenesis, Site-Directed ; Protein Binding ; Protein Structure, Tertiary ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification

المؤلفون: Lehmann LC; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Hewitt G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Aibara S; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17165 Solna, Sweden., Leitner A; Department of Biology, Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, 8093 Zürich, Switzerland., Marklund E; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., Maslen SL; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK., Maturi V; Department of Medical Biochemistry and Microbiology, and Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, 75123 Uppsala, Sweden., Chen Y; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden., van der Spoel D; Department of Cell and Molecular Biology, Computational Biology and Bioinformatics, Uppsala University, 75124 Uppsala, Sweden., Skehel JM; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK., Moustakas A; Department of Medical Biochemistry and Microbiology, and Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, 75123 Uppsala, Sweden., Boulton SJ; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: simon.boulton@crick.ac.uk., Deindl S; Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden. Electronic address: sebastian.deindl@icm.uu.se.

المصدر: Molecular cell [Mol Cell] 2017 Dec 07; Vol. 68 (5), pp. 847-859.e7.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin Assembly and Disassembly* , DNA Damage* , DNA Repair*, DNA Helicases/*metabolism , DNA-Binding Proteins/*metabolism , Nucleosomes/*enzymology, Catalytic Domain ; Cell Line, Tumor ; DNA Helicases/chemistry ; DNA Helicases/genetics ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Enzyme Activation ; Humans ; Microscopy, Electron ; Molecular Dynamics Simulation ; Mutation ; Nucleosomes/chemistry ; Poly (ADP-Ribose) Polymerase-1/chemistry ; Poly (ADP-Ribose) Polymerase-1/metabolism ; Poly ADP Ribosylation ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Transport ; Scattering, Small Angle ; Static Electricity ; Structure-Activity Relationship ; Time Factors ; X-Ray Diffraction