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1
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2دورية أكاديمية
المؤلفون: Ma J; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; Ministry of Health Holdings, Singapore 099253, Singapore., Al Moussawi K; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Lou H; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Chan HF; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Wang Y; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom., Chadwick J; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Phetsouphanh C; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; The Kirby Institute, University of New South Wales, Kensington, NSW 2052, Australia., Slee EA; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Zhong S; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Leissing TM; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Roth A; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; Department of Molecular Oncology, BC Cancer, Vancouver, BC V5Z 4E6, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada.; Department of Computer Science, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Qin X; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; Department of Oncology, Faculty of Medical Sciences, University College London, London WC1E 6BT, United Kingdom., Chen S; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Yin J; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Ratnayaka I; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Hu Y; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Louphrasitthiphol P; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Taylor L; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., Bettencourt PJG; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.; Center for Interdisciplinary Research in Health, Faculty of Medicine, Universidade Católica Portuguesa, Lisbon 1649-023, Portugal., Muers M; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom., McShane H; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Goldin R; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W2 1NY, United Kingdom., Soilleux EJ; Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom., Coleman ML; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom., Ratcliffe PJ; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Lu X; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.
المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 05; Vol. 121 (10), pp. e2309957121. Date of Electronic Publication: 2024 Feb 29.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
مواضيع طبية MeSH: Lymphoma, B-Cell* , Repressor Proteins*/metabolism, Animals ; Mice ; Hypoxia/metabolism ; Mixed Function Oxygenases/metabolism ; Tumor Microenvironment
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3دورية أكاديمية
المؤلفون: Saward BG; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK., Leissing TM; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK., Clifton IJ; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK., Tumber A; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK., Timperley CM; CBR Division, Defence Science and Technology Laboratory (DSTL), Porton Down, Salisbury, SP4 0JQ, UK., Hopkinson RJ; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK.; Present address: Leicester Institute for Structural and Chemical Biology and School of Chemistry, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester, LE1 7RH, UK., Schofield CJ; Department of Chemistry and the, Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, Mansfield Road, University of Oxford, Oxford, OX1 3TA, UK.
المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Feb 14; Vol. 24 (4), pp. e202200576. Date of Electronic Publication: 2023 Jan 09.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE
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4دورية أكاديمية
المؤلفون: Leissing TM; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom., Hardy AP; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom., Chan H; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom., Wang Y; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom., Tumber A; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom., Chowdhury R; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom., Feng T; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom; NDM Research Building, University of Oxford, Oxford, United Kingdom., Coleman ML; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom., Cockman ME; The Francis Crick Institute, Ratcliffe Laboratory, London, United Kingdom., Kramer HB; MRC London Institute of Medical Sciences, London, United Kingdom; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom., Berridge G; NDM Research Building, University of Oxford, Oxford, United Kingdom., Fischer R; NDM Research Building, University of Oxford, Oxford, United Kingdom., Kessler BM; NDM Research Building, University of Oxford, Oxford, United Kingdom., Ratcliffe PJ; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom; The Francis Crick Institute, Ratcliffe Laboratory, London, United Kingdom. Electronic address: peter.ratcliffe@ndm.ox.ac.uk., Lu X; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom. Electronic address: xin.lu@ludwig.ox.ac.uk., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom. Electronic address: christopher.schofield@chem.ox.ac.uk.
المصدر: The Journal of biological chemistry [J Biol Chem] 2022 Jun; Vol. 298 (6), pp. 102020. Date of Electronic Publication: 2022 May 07.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
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5دورية أكاديمية
المؤلفون: Brem J; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK. jurgen.brem@chem.ox.ac.uk., Panduwawala T; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Hansen JU; Statens Serum Institut, Copenhagen, Denmark., Hewitt J; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK., Liepins E; Latvian Institute of Organic Synthesis, Riga, Latvia., Donets P; Latvian Institute of Organic Synthesis, Riga, Latvia., Espina L; Department of Medical Microbiology, Institute of infection & Immunity, Cardiff University, Cardiff, UK., Farley AJM; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Shubin K; Latvian Institute of Organic Synthesis, Riga, Latvia., Campillos GG; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Kiuru P; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Shishodia S; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA., Krahn D; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Leśniak RK; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Schmidt Adrian J; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Calvopiña K; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Turrientes MC; Department of Microbiology, Ramón y Cajal University Hospital and Ramón y Cajal Institute for Health Research (IRYCIS), Madrid, Spain., Kavanagh ME; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Lubriks D; Latvian Institute of Organic Synthesis, Riga, Latvia., Hinchliffe P; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Langley GW; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK.; Charles River Laboratories, Saffron Walden, UK., Aboklaish AF; Department of Medical Microbiology, Institute of infection & Immunity, Cardiff University, Cardiff, UK., Eneroth A; Department of Pharmacy, Uppsala Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala University, Uppsala, Sweden., Backlund M; Department of Pharmacy, Uppsala Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala University, Uppsala, Sweden., Baran AG; Latvian Institute of Organic Synthesis, Riga, Latvia., Nielsen EI; Department of Pharmacy, Uppsala University, Uppsala, Sweden., Speake M; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., Kuka J; Latvian Institute of Organic Synthesis, Riga, Latvia., Robinson J; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., Grinberga S; Latvian Institute of Organic Synthesis, Riga, Latvia., Robinson L; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., McDonough MA; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Rydzik AM; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK.; Research and Early Development, Respiratory & Immunology, AstraZeneca, Mölndal, Sweden., Leissing TM; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Jimenez-Castellanos JC; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.; Chemical Biology of Antibiotics, Centre for Infection & Immunity (CIIL), Pasteur Institute, INSERM U1019 - CNRS UMR 9017, Lille, France., Avison MB; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Da Silva Pinto S; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Pannifer AD; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK., Martjuga M; Latvian Institute of Organic Synthesis, Riga, Latvia., Widlake E; Department of Medical Microbiology, Institute of infection & Immunity, Cardiff University, Cardiff, UK., Priede M; Latvian Institute of Organic Synthesis, Riga, Latvia., Hopkins Navratilova I; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK., Gniadkowski M; Department of Molecular Microbiology, National Medicines Institute, Warsaw, Poland., Belfrage AK; Department of Medicinal Chemistry, Drug Design and Discovery, Uppsala University, Uppsala, Sweden., Brandt P; Department of Medicinal Chemistry, Drug Design and Discovery, Uppsala University, Uppsala, Sweden.; Beactica Therapeutics AB, Uppsala, Sweden., Yli-Kauhaluoma J; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Bacque E; Evotec Infectious Diseases Lyon, Marcy l'Etoile, France., Page MGP; Jacobs University Bremen gGmbH, Bremen, Germany., Björkling F; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Tyrrell JM; Department of Medical Microbiology, Institute of infection & Immunity, Cardiff University, Cardiff, UK.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Spencer J; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Lang PA; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Baranczewski P; Department of Pharmacy, SciLifeLab Drug Discovery and Development Platform, ADME of Therapeutics Facility, Uppsala University, Uppsala, Sweden., Cantón R; Department of Microbiology, Ramón y Cajal University Hospital and Ramón y Cajal Institute for Health Research (IRYCIS), Madrid, Spain., McElroy SP; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., Jones PS; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., Baquero F; Department of Microbiology, Ramón y Cajal University Hospital and Ramón y Cajal Institute for Health Research (IRYCIS), Madrid, Spain., Suna E; Latvian Institute of Organic Synthesis, Riga, Latvia., Morrison A; University of Dundee, European Screening Centre, BioCity Scotland, Newhouse, UK.; BioAscent Discovery Ltd, Newhouse, UK., Walsh TR; Department of Medical Microbiology, Institute of infection & Immunity, Cardiff University, Cardiff, UK., Schofield CJ; Department of Chemistry, Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK. christopher.schofield@chem.ox.ac.uk.
المصدر: Nature chemistry [Nat Chem] 2022 Jan; Vol. 14 (1), pp. 15-24. Date of Electronic Publication: 2021 Dec 13.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101499734 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-4349 (Electronic) Linking ISSN: 17554330 NLM ISO Abbreviation: Nat Chem Subsets: MEDLINE
مواضيع طبية MeSH: beta-Lactamase Inhibitors/*pharmacology , beta-Lactams/*metabolism, Animals ; Gram-Negative Bacteria/drug effects ; Humans ; Mice ; Microbial Sensitivity Tests ; Protein Binding ; Structure-Activity Relationship ; beta-Lactamase Inhibitors/chemistry ; beta-Lactamase Inhibitors/metabolism
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6دورية أكاديمية
المؤلفون: Shishodia S; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Demetriades M; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Zhang D; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Tam NY; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR 999077, China., Maheswaran P; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Clunie-O'Connor C; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Tumber A; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Leung IKH; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Ng YM; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR 999077, China., Leissing TM; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., El-Sagheer AH; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.; Chemistry Branch Department of Science and Mathematics, Suez University, Suez 43721, Egypt., Salah E; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Brown T; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Aik WS; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR 999077, China., McDonough MA; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K., Schofield CJ; The Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Nov 25; Vol. 64 (22), pp. 16609-16625. Date of Electronic Publication: 2021 Nov 11.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Drug Design*, Alpha-Ketoglutarate-Dependent Dioxygenase FTO/*antagonists & inhibitors , Antineoplastic Agents/*pharmacology, Antineoplastic Agents/chemistry ; Crystallography, X-Ray ; Histone Demethylases/metabolism ; Humans ; Mixed Function Oxygenases/metabolism ; Structure-Activity Relationship
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7دورية أكاديمية
المؤلفون: Rabe P; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Kamps JJAG; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.; Diamond Light Source, Diamond House, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0FA, UK., Sutherlin KD; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Linyard JDS; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Aller P; Diamond Light Source, Diamond House, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0FA, UK., Pham CC; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Makita H; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Clifton I; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., McDonough MA; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Leissing TM; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Shutin D; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Lang PA; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Butryn A; Diamond Light Source, Diamond House, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0FA, UK., Brem J; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Gul S; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Fuller FD; Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA., Kim IS; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Cheah MH; Department of Chemistry - Ångström, Molecular Biomimetics, Uppsala University, SE 751 20 Uppsala, Sweden., Fransson T; Interdisciplinary Center for Scientific Computing, University of Heidelberg, 69120 Heidelberg, Germany., Bhowmick A; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Young ID; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA., O'Riordan L; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Brewster AS; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Pettinati I; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Doyle M; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Joti Y; Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198, Japan.; RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148, Japan., Owada S; Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198, Japan.; RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148, Japan., Tono K; Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198, Japan.; RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148, Japan., Batyuk A; Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA., Hunter MS; Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA., Alonso-Mori R; Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA., Bergmann U; Stanford PULSE Institute, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.; Department of Physics, University of Wisconsin-Madison, 1150 University Avenue, Madison, WI 53706, USA., Owen RL; Diamond Light Source, Diamond House, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK., Sauter NK; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Claridge TDW; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Robinson CV; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK., Yachandra VK; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Yano J; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA., Kern JF; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA. christopher.schofield@chem.ox.ac.uk allen.orville@diamond.ac.uk jfkern@lbl.gov., Orville AM; Diamond Light Source, Diamond House, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK. christopher.schofield@chem.ox.ac.uk allen.orville@diamond.ac.uk jfkern@lbl.gov.; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0FA, UK., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. christopher.schofield@chem.ox.ac.uk allen.orville@diamond.ac.uk jfkern@lbl.gov.
المصدر: Science advances [Sci Adv] 2021 Aug 20; Vol. 7 (34). Date of Electronic Publication: 2021 Aug 20 (Print Publication: 2021).
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
مواضيع طبية MeSH: Electrons* , Oxidoreductases*/chemistry, Catalysis ; Catalytic Domain ; Crystallography, X-Ray ; Ferric Compounds ; Humans ; Lasers ; Oxygen/chemistry ; Penicillins/chemistry ; Penicillins/metabolism ; Substrate Specificity
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8دورية أكاديمية
المؤلفون: Lang PA; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom., Leissing TM; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom., Page MGP; Jacobs University Bremen gGmbH, Bremen, Germany., Schofield CJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom christopher.schofield@chem.ox.ac.uk jurgen.brem@chem.ox.ac.uk., Brem J; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom christopher.schofield@chem.ox.ac.uk jurgen.brem@chem.ox.ac.uk.
المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jan 20; Vol. 65 (2). Date of Electronic Publication: 2021 Jan 20 (Print Publication: 2021).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
مواضيع طبية MeSH: Escherichia coli*/genetics , beta-Lactamase Inhibitors*/pharmacology, Anti-Bacterial Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Bacterial Proteins/genetics ; Microbial Sensitivity Tests ; beta-Lactamases/genetics
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9دورية أكاديمية
المؤلفون: Leissing TM; Evotec SE, Essener Bogen 7, 22419 Hamburg, Germany., Luh LM; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Cromm PM; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany. Electronic address: philipp.cromm@bayer.com.
المصدر: Drug discovery today. Technologies [Drug Discov Today Technol] 2020 Dec; Vol. 37, pp. 73-82. Date of Electronic Publication: 2020 Dec 10.
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101235076 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-6749 (Electronic) Linking ISSN: 17406749 NLM ISO Abbreviation: Drug Discov Today Technol Subsets: MEDLINE
مواضيع طبية MeSH: Proteasome Endopeptidase Complex*/metabolism , Ubiquitin-Protein Ligases*/metabolism, Proteolysis ; Ubiquitin ; Ubiquitination
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10دورية أكاديمية
المؤلفون: Lemos C; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Schulze L; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Weiske J; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Meyer H; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Braeuer N; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Barak N; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Eberspächer U; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Werbeck N; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Stresemann C; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Lange M; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Lesche R; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Zablowsky N; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Juenemann K; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Kamburov A; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Luh LM; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Leissing TM; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Mortier J; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Steckel M; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Steuber H; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Eis K; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Eheim A; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany., Steigemann P; Bayer AG Research and Development, Pharmaceuticals, Müllerstr. 178, 13342 Berlin, Germany.
المصدر: IScience [iScience] 2020 Sep 01; Vol. 23 (9), pp. 101517. Date of Electronic Publication: 2020 Sep 01 (Print Publication: 2020).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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