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1دورية أكاديمية
المؤلفون: Anjili Mathur, Christopher Ware, Lenora Davis, Adi Gazdar, Bo-Sheng Pan, Bart Lutterbach
المصدر: PLoS ONE, Vol 9, Iss 6, p e98515 (2014)
وصف الملف: electronic resource
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المؤلفون: Jason D. Katz, Bart Lutterbach, Harold Hatch, Robert J. Mathvink, Wenxian Wang, Xianlu Qu, Kaiko Kunii, C. Gary Marshall, Bo-Sheng Pan, Keith W. Rickert, Craig Rosenstein, Alexander A. Szewczak, Jonathan R. Young, Kevin J. Lumb, David Joseph Guerin, Sangita B. Patel, Gaozhen Hang, Qinwen Zeng, Sujal V. Deshmukh, Deborah Walker, Danielle Falcone, Stephen M. Soisson, Lenora Davis, Rachael Holmes, Kerrie Spencer, William K. Dahlberg, Wei Lu, James P. Jewell, Ana Esther Ortega Gabarda, Naim Nazef, Michael D. Altman, Christopher J. Dinsmore, John F. Reilly, Jongwon Lim
المصدر: Journal of Medicinal Chemistry. 54:4092-4108
مصطلحات موضوعية: Models, Molecular, C-Met, Pyridines, Transplantation, Heterologous, Mice, Nude, Antineoplastic Agents, Crystallography, X-Ray, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Phosphorylation, Sulfonamides, biology, Chemistry, Cyclin-dependent kinase 4, Kinase, Receptor Protein-Tyrosine Kinases, Cancer, Haplorhini, medicine.disease, Transmembrane protein, Rats, Benzocycloheptenes, Biochemistry, Mutation, Cancer research, biology.protein, Pyrazoles, Molecular Medicine, Female, Drug Screening Assays, Antitumor, Signal transduction, Tyrosine kinase, Neoplasm Transplantation, Protein Binding
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المؤلفون: Lenora Davis, Alessandra Di Bacco, Harold Hatch, Kaiko Kunii, Bart Lutterbach, Cem Elbi, Masakazu Yashiro, Julie Gorenstein
المصدر: Cancer Research. 68:2340-2348
مصطلحات موضوعية: musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, Receptor, ErbB-3, Apoptosis, Cell Growth Processes, Biology, Fibroblast growth factor, Gefitinib, Stomach Neoplasms, Cell Line, Tumor, Internal medicine, medicine, Humans, ERBB3, Phosphorylation, RNA, Small Interfering, Receptor, Fibroblast Growth Factor, Type 2, integumentary system, Cell growth, Fibroblast growth factor receptor 2, Gene Amplification, Cancer, medicine.disease, stomatognathic diseases, Pyrimidines, Endocrinology, Oncology, embryonic structures, Cancer research, Erlotinib, Signal transduction, Signal Transduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5200b0f67fbfe60e507fa1e57dc4a12e
https://doi.org/10.1158/0008-5472.can-07-5229 -
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المؤلفون: Xianzhi Mao, Elaine Rands, Laura Sepp-Lorenzino, Patrice A. Ciecko, Susan Hill, Jennifer M. Shipman, William F. Hoffman, Brett Connolly, Mark E. Fraley, Stephen C. Beck, Kathleen E. Coll, Kenneth A. Thomas, David C. Heimbrook, Keith W. Rickert, Lenora Davis, Jackson B. Gibbs, Nancy E. Kohl, Joanne Antanavage, George D. Hartman
المصدر: Cancer Research. 64:751-756
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, medicine.medical_specialty, Angiogenesis, Fibrosarcoma, Transplantation, Heterologous, Administration, Oral, Biological Availability, Mice, Nude, Angiogenesis Inhibitors, Antineoplastic Agents, Pharmacology, Biology, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, Enzyme Inhibitors, Phosphorylation, Kinase activity, Autophosphorylation, Kinase insert domain receptor, Tyrosine phosphorylation, Vascular Endothelial Growth Factor Receptor-2, Vascular endothelial growth factor, Endocrinology, Oncology, chemistry, Cell Division
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcb0bf205e5ae41fb8194e8859404d5
https://doi.org/10.1158/0008-5472.can-03-2871 -
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المؤلفون: Christopher Ware, Adi F. Gazdar, Bo Sheng Pan, Bart Lutterbach, Lenora Davis, Anjili Mathur
المصدر: PLoS ONE, Vol 9, Iss 6, p e98515 (2014)
PLoS ONEمصطلحات موضوعية: MAPK/ERK pathway, Colorectal cancer, Cancer Treatment, lcsh:Medicine, Biochemistry, Mice, 0302 clinical medicine, Cell Signaling, Tyrosine Kinase Signaling Cascade, Molecular Cell Biology, Basic Cancer Research, Drug Discovery, Medicine and Health Sciences, lcsh:Science, Mice, Inbred BALB C, 0303 health sciences, Multidisciplinary, Cell Death, integumentary system, Kinase, NF-kappa B, Genomics, Signaling Cascades, 3. Good health, Oncology, Cell Processes, 030220 oncology & carcinogenesis, embryonic structures, Colorectal Neoplasms, Research Article, Biotechnology, Signal Transduction, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Drug Research and Development, Cell Survival, Mice, Nude, Mouse model of colorectal and intestinal cancer, Cell Growth, 03 medical and health sciences, Cell Line, Tumor, Gastrointestinal Tumors, Genetics, medicine, Animals, Humans, Viability assay, Receptor, Fibroblast Growth Factor, Type 2, Protein kinase B, Cell Proliferation, 030304 developmental biology, Pharmacology, Mitogen-Activated Protein Kinase Kinases, business.industry, Cell growth, lcsh:R, Gene Amplification, Biology and Life Sciences, Cancers and Neoplasms, Cancer, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, stomatognathic diseases, Pyrimidines, Small Molecules, Immunology, Cancer research, lcsh:Q, business, Proto-Oncogene Proteins c-akt
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المؤلفون: Lloyd Waxman, Lenora Davis, Kuo-Chang Yin, Xiao-Ping Shi, Andrew M. Stern, Ahern Janet
المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1310:119-126
مصطلحات موضوعية: Guanine, Deoxyhypusine synthase, Population, Cell, Tumorigenic cell line, Biology, Guanidines, HeLa, Cell growth, Mice, chemistry.chemical_compound, Peptide Initiation Factors, Tumor Cells, Cultured, medicine, Animals, Humans, Enzyme Inhibitors, education, Molecular Biology, Cell Line, Transformed, Oxidoreductases Acting on CH-NH Group Donors, education.field_of_study, Chinese hamster ovary cell, Cell Cycle, RNA-Binding Proteins, 3T3 Cells, Cell Biology, Antiproliferation, Cell cycle, biology.organism_classification, Molecular biology, medicine.anatomical_structure, chemistry, Cell culture, Puromycin, biology.protein, Eukaryotic translation initiation factor 5A, Cell Division, HeLa Cells
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المؤلفون: Massimo Loda, Elisa Benedettini, Bo Sheng Pan, Victoria M. Richon, Michelangelo Fiorentino, John F. Reilly, Dyane Bailey, Lenora Davis, Lucian R. Chirieac, John D. Minna, Natalie Vena, Silvano Bosari, Christopher Ware, Bart Lutterbach, Azra H. Ligon, Adi F. Gazdar, Michael Peyton, Giulio Draetta, Beow Y. Yeap, Lynette M. Sholl
المساهمون: Benedettini E, Sholl LM, Peyton M, Reilly J, Ware C, Davis L, Vena N, Bailey D, Yeap BY, Fiorentino M, Ligon AH, Pan BS, Richon V, Minna JD, Gazdar AF, Draetta G, Bosari S, Chirieac LR, Lutterbach B, Loda M
مصطلحات موضوعية: medicine.drug_class, Tyrosine-kinase inhibitor, Pathology and Forensic Medicine, Metastasis, Carcinoma, Non-Small-Cell Lung, EGFR mutations MET amplification lung cancer NSCLC, medicine, Carcinoma, Humans, Epidermal growth factor receptor, Lung cancer, Protein Kinase Inhibitors, In Situ Hybridization, Fluorescence, EGFR inhibitors, biology, Brain Neoplasms, business.industry, Cancer, Proto-Oncogene Proteins c-met, medicine.disease, respiratory tract diseases, Enzyme Activation, ErbB Receptors, Survival Rate, Drug Resistance, Neoplasm, Mutation, Immunology, Cancer research, biology.protein, Female, business, Regular Articles, Brain metastasis
وصف الملف: STAMPA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56e62ac6232b5f60d5a3c1bf3469316
http://hdl.handle.net/11585/577838 -
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المؤلفون: Edward M. Scolnick, Scott D. Mosser, R D Keys, Lenora Davis, Jackson B. Gibbs, Mark S. Marshall, W. S. Hill
المصدر: Molecular and Cellular Biology. 11:3997-4004
مصطلحات موضوعية: chemistry.chemical_classification, Effector, Rap GTP-binding protein, Cell Biology, Biology, SH3 domain, Amino acid, chemistry, Biochemistry, Oncogene Protein p21(ras), NCK1, HRAS, Molecular Biology, Peptide sequence
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