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1
المؤلفون: Wietfeld Bernhard, Xiangguang Tian, Yong Zhang, Franck Mallet, Richard Kaehny, Cheng Li, Leo A. Hardegger, Bo Yu, Jeannine Stäuble, Lei Shi, Barbara Bianchi, Florian Andreas Rampf, Jialiang Li, Stephan Lanz, Christoph Spoendlin, Christine Zepperitz, Xuesong Zhang, Shangjun Teng, Chunlong Cai, Yao Yang, Roger Humair, Alexandre Grand-Guillaume Perrenoud
المصدر: Organic Process Research & Development. 24:1743-1755
مصطلحات موضوعية: Process development, Chemistry, Organic Chemistry, Late stage, EMA401, Physical and Theoretical Chemistry, Combinatorial chemistry, Angiotensin II, Phenylalanine derivatives
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2
المؤلفون: Eric Sidler, Roger Humair, Leo A. Hardegger
المصدر: Organic Process Research & Development. 24:1756-1762
مصطلحات موضوعية: chemistry.chemical_classification, Organic Chemistry, Condensation, Combinatorial chemistry, Angiotensin II, Cinnamic acid, Amino acid, chemistry.chemical_compound, chemistry, Pyridine, Knoevenagel condensation, Piperidine, Physical and Theoretical Chemistry, Derivative (chemistry)
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3
المؤلفون: Alexandre Grand-Guillaume Perrenoud, Julien Haber, Florian Andreas Rampf, Van Tong Luu, Roger Humair, Wietfeld Bernhard, Michael Kibiger, Thomas Ruch, Lukas Padeste, Tao Hong, Pascal Beney, Yao Yang, Anikó Udvarhelyi, Leo A. Hardegger, Eric Sidler, Andreas Kaegi, Xingxian Gu, Dominique Bixel, Christian Fleury, Feng Gao, Thierry Schlama, Florian Kleinbeck
المصدر: Organic Process Research & Development. 24:1763-1771
مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Process development, Chemistry, Organic Chemistry, Phenylalanine, Phenylalanine ammonia-lyase, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Part iii, chemistry.chemical_compound, Enzyme, Biocatalysis, Physical and Theoretical Chemistry, Derivative (chemistry)
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4
المؤلفون: Birgit S. Lauber, Leo A. Hardegger, Kazi A. Alam, Bjarte A. Lund, Oliver Dumele, Michael Harder, Bernd Kuhn, Richard A. Engh, François Diederich
المصدر: Chemistry (Weinheim an der Bergstrasse, Germany). 26(39)
مصطلحات موضوعية: Organic Chemistry, General Chemistry, Catalysis
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5
المؤلفون: Michael Harder, Leo A. Hardegger, Oliver Dumele, Alam K. Asraful, Birgit Sophia Lauber, François Diederich, Richard A. Engh, Bjarte Aarmo Lund, Bernd Kuhn
المصدر: Chemistry - A European Journal. 22:211-221
مصطلحات موضوعية: Models, Molecular, Hydrocarbons, Fluorinated, Stereochemistry, Glycine, Crystallography, X-Ray, Ligands, 010402 general chemistry, 01 natural sciences, Catalysis, chemistry.chemical_compound, Molecular recognition, Drug Discovery, Ribose, Transferase, Amino Acid Sequence, Binding site, Protein kinase A, Protein Kinase Inhibitors, Protein kinase B, Binding Sites, 010405 organic chemistry, Drug discovery, Kinase, Organic Chemistry, Intracellular Signaling Peptides and Proteins, General Chemistry, 0104 chemical sciences, chemistry, Protein Kinases
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6
المؤلفون: Jeremy M Sivak, Leo A. Hardegger, Stephen Poor, Elizabeth Fassbender, Keith Jendza, Jason Elliott, Shawn Hanks, Debby Long, Chun Zhang, Fang Liu, Rosemarie Cepeda, Amber Woolfenden, Karl Miranda, Leland Johnson, Powers James J, Malay Ghosh, Donglei Liu, Wendy Lee, Vinayak Hosagrahara, Nello Mainolfi, Christopher M. Adams, Catherine Solovay, Bruce D Jaffee, Nan Ji, Erik Meredith, Fupeng Ma, Karen Anderson, Jean-Claude Bizec, Yubin Qiu, Gerald D. Artman, Peter Tarsa, Yao Peng, Yiqin Zhang, Siyuan Shen, Chang Rao
المصدر: Journal of medicinal chemistry. 61(4)
مصطلحات موضوعية: 0301 basic medicine, Indoles, genetic structures, medicine.drug_class, VEGF receptors, Administration, Topical, Carboxamide, Rodentia, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Drug Discovery, medicine, Potency, Animals, Protein Kinase Inhibitors, Indole test, Trifluoromethyl, biology, Macular degeneration, medicine.disease, Vascular Endothelial Growth Factor Receptor-2, eye diseases, Choroidal Neovascularization, 030104 developmental biology, Choroidal neovascularization, Pyrimidines, chemistry, 030221 ophthalmology & optometry, biology.protein, Wet Macular Degeneration, Molecular Medicine, Pyrazoles, sense organs, Rabbits, medicine.symptom, Ophthalmic Solutions
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7
المؤلفون: Leo A. Hardegger, Jacqueline Habegger, Timothy J. Donohoe
المصدر: ChemInform. 46
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Ketone, chemistry, Pyridine, General Medicine, Methylene, Combinatorial chemistry, Catalysis
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8
المؤلفون: Robert Ecabert, Yoshiaki Isshiki, Joachim Diez, Beat Spinnler, Guido Hartmann, Jean-Marc Plancher, Wolfgang Haap, François Diederich, David Banner, Nobuo Shimma, Ralf Thoma, Bernd Kuhn, Jörg Benz, Kenji Morikami, Bernard Gsell, Lilli Anselm, Martine Stihle, Leo A. Hardegger
المصدر: ChemMedChem. 6:2048-2054
مصطلحات موضوعية: Stereochemistry, Cathepsin L, MAP Kinase Kinase 1, Crystallography, X-Ray, Ligands, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Halogens, Molecular recognition, Catalytic Domain, Drug Discovery, Hydrolase, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Halogen bond, Ligand, Chemistry, Aryl, Organic Chemistry, Affinities, Acceptor, Halogen, Molecular Medicine, Protein Binding
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9
المؤلفون: Leo A. Hardegger, Wolfgang Haap, Lilli Anselm, Joachim Diez, David Banner, François Diederich, Beat Spinnler, Bernd Kuhn, Jean-Marc Plancher, Bernard Gsell, Guido Hartmann, Jörg Benz, Martine Stihle, Robert Ecabert, Ralf Thoma
المصدر: Angewandte Chemie. 123:329-334
مصطلحات موضوعية: Chemistry, General Medicine
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10
المؤلفون: Christoph Fäh, Solange Meyer, Leo A. Hardegger, Daniel Bur, Roland Mathys, François Diederich
المصدر: European Journal of Organic Chemistry. 2010:4617-4629
مصطلحات موضوعية: chemistry.chemical_classification, Ketone, biology, Stereochemistry, Organic Chemistry, Absolute configuration, Diastereomer, Plasmepsin, Active site, Chemical synthesis, Chiral resolution, Alicyclic compound, chemistry, biology.protein, Physical and Theoretical Chemistry