-
1
المؤلفون: Ling-Jen Chen, Leo T. Burka
المصدر: Chemical Research in Toxicology. 20:1741-1744
مصطلحات موضوعية: Male, Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Metabolite, Carboxylic acid, Pyridinium Compounds, Toxicology, Aldehyde, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Nucleophile, Furosemide, medicine, Animals, Organic chemistry, Dimethyldioxirane, Diuretics, Biotransformation, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Molecular Structure, Chemistry, General Medicine, Rats, Inbred F344, Rats, Microsomes, Liver, Epoxy Compounds, Salts, Pyridinium, Oxidation-Reduction, Enone, medicine.drug
-
2
المؤلفون: Fred B. Lih, Ling-Jen Chen Ferguson, Edward H. Lebetkin, Horace D. Parkinson, Kenneth B. Tomer, Leo T Burka, Susan J. Borghoff
المصدر: Journal of Toxicology and Environmental Health, Part A. 70:1416-1423
مصطلحات موضوعية: Male, Menthofuran, Chromatography, Health, Toxicology and Mutagenesis, Kidney Glomerulus, Cyclohexane Monoterpenes, Pennyroyal Oil, Metabolism, Toxicology, Menthone, High-performance liquid chromatography, Rats, Menthol, chemistry.chemical_compound, Sex Factors, chemistry, Alpha-Globulins, Monoterpenes, Animals, Female, Carbon Radioisotopes, Pulegone, Metabolic Networks and Pathways, Pennyroyal, Corn oil
-
3
المؤلفون: Po-Chuen Chan, Grace E. Kissling, Leo T. Burka, Natasha P. Clayton, Katsuhiko Yoshizawa, Abraham Nyska
المصدر: Experimental and Toxicologic Pathology. 58:223-236
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Administration, Oral, Toxicology, Article, Pathology and Forensic Medicine, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Liver Function Tests, Oral administration, Internal medicine, medicine, Animals, Gamma-glutamyltransferase, health care economics and organizations, Kava, Dose-Response Relationship, Drug, medicine.diagnostic_test, biology, Piper methysticum, Cholesterol, CYP1A2, Hypertrophy, gamma-Glutamyltransferase, Cell Biology, General Medicine, Immunohistochemistry, Rats, Inbred F344, Rats, Endocrinology, Liver, chemistry, Dietary Supplements, Toxicity, biology.protein, Female, Liver function tests
-
4
المؤلفون: Leo T. Burka, E. H. Lebetkin, L.-J. Chen, J. M. Sanders
المصدر: Xenobiotica. 36:515-534
مصطلحات موضوعية: Male, medicine.medical_specialty, Health, Toxicology and Mutagenesis, F344 rats, Administration, Oral, Adipose tissue, Ether, Urine, Toxicology, Biochemistry, Mice, chemistry.chemical_compound, Sex Factors, Species Specificity, Internal medicine, Halogenated Diphenyl Ethers, medicine, Animals, Feces, Pharmacology, Carbon Isotopes, Dose-Response Relationship, Drug, Chemistry, Phenyl Ethers, General Medicine, Metabolism, Rats, Inbred F344, Pentabromodiphenyl ether, Rats, Endocrinology, Adipose Tissue, Female, Glucuronide, Oxidation-Reduction
-
5
المؤلفون: L.-J. Chen, Leo T. Burka, E. H. Lebetkin, J. M. Sanders
المصدر: Xenobiotica. 36:103-117
مصطلحات موضوعية: Male, medicine.medical_specialty, Metabolic Clearance Rate, Health, Toxicology and Mutagenesis, Polybrominated Biphenyls, Urine, Absorption (skin), Toxicology, Biochemistry, Drug Administration Schedule, Excretion, Mice, chemistry.chemical_compound, Sulfate conjugate, Species Specificity, Oral administration, Internal medicine, Halogenated Diphenyl Ethers, medicine, Animals, Tissue Distribution, Pharmacology, Dose-Response Relationship, Drug, biology, Chemistry, Phenyl Ethers, General Medicine, Metabolism, Glutathione, Rats, Inbred F344, Hydrocarbons, Brominated, Rats, Endocrinology, Organ Specificity, biology.protein, Female, Glucuronide
-
6
المؤلفون: Michael L. Cunningham, Leo T. Burka, W. Black, C. S. Smith, R. James, J. M. Sanders
المصدر: Toxicological Sciences. 88:127-133
مصطلحات موضوعية: Male, endocrine system, medicine.medical_specialty, CYP3A, Polybrominated Biphenyls, Administration, Oral, Complex Mixtures, Toxicology, Gene Expression Regulation, Enzymologic, chemistry.chemical_compound, Polybrominated diphenyl ethers, Internal medicine, Cytochrome P-450 CYP1A1, Halogenated Diphenyl Ethers, medicine, Animals, Cytochrome P-450 CYP3A, RNA, Messenger, reproductive and urinary physiology, Flame Retardants, biology, Reverse Transcriptase Polymerase Chain Reaction, Phenyl Ethers, Diphenyl ether, Oxidoreductases, N-Demethylating, Aryl hydrocarbon receptor, Rats, Inbred F344, Rats, Up-Regulation, Endocrinology, chemistry, Environmental chemistry, Cytochrome P-450 CYP2B1, Toxicity, biology.protein, Androstane, Aryl Hydrocarbon Hydroxylases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e27d34d2919d6d17376167d2505d85
https://doi.org/10.1093/toxsci/kfi288 -
7
المؤلفون: James So, Leo T. Burka, James M. Mathews, Donna P. Coleman, Amy S. Etheridge, Purvi R. Patel, John L Valentine, Sherry R Black
المصدر: Drug Metabolism and Disposition. 33:1555-1563
مصطلحات موضوعية: Male, Administration, Oral, Biological Availability, Pharmaceutical Science, Pharmacology, Dihydromethysticin, Lactones, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Pharmacokinetics, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Kava, Adenosine Triphosphatases, Desmethoxyyangonin, Plant Extracts, Piper methysticum, Kavalactone, Rats, Inbred F344, Rats, Anti-Anxiety Agents, chemistry, Pyrones, Injections, Intravenous, Microsomes, Liver, Methysticin, Drug metabolism, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d06cf99839655dadf689fdc41c3ba9e
https://doi.org/10.1124/dmd.105.004317 -
8
المؤلفون: Molly Vallant, Gary A. Boorman, Diane F. Gerken, Edward H. Lebetkin, Leo T. Burka, Irwin D. Richard, Pamela E. Blackshear, Joel S. Parker, Edward K. Lobenhofer
المصدر: Toxicologic Pathology. 33:111-117
مصطلحات موضوعية: Male, medicine.medical_specialty, Microarray, 040301 veterinary sciences, Biology, Toxicology, 030226 pharmacology & pharmacy, Pathology and Forensic Medicine, 0403 veterinary science, Transcriptome, Necrosis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Gene expression, medicine, Animals, Molecular Biology, Gene, Acetaminophen, Oligonucleotide Array Sequence Analysis, Inflammation, Dose-Response Relationship, Drug, Gene Expression Profiling, 04 agricultural and veterinary sciences, Cell Biology, Analgesics, Non-Narcotic, Rats, Inbred F344, Rats, Endocrinology, Liver, Liver Lobe, DNA microarray, Drug metabolism, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e321a4d4cc2aaa4b5de4d2e82cced4d5
https://doi.org/10.1080/01926230590522257 -
9
المؤلفون: Denise Orzech, Kristine L. Witt, John R. Bucher, Jerry D. Johnson, A.F. Fuciarelli, Steven W. Graves, Michelle J. Hooth, Leo T. Burka, Robert C. Sills, Joseph K. Haseman
المصدر: Food and Chemical Toxicology. 42:1757-1768
مصطلحات موضوعية: Male, Carcinogenicity Tests, Ratón, Drug Compounding, Administration, Oral, Mice, Inbred Strains, Absorption (skin), Biology, Toxicology, Excretion, Mice, Random Allocation, chemistry.chemical_compound, medicine, Animals, Longitudinal Studies, Acrolein, Carcinogen, Dose-Response Relationship, Drug, Stomach, Body Weight, Hippuric acid, General Medicine, Survival Analysis, Rats, Inbred F344, Rats, Flavoring Agents, Dose–response relationship, medicine.anatomical_structure, chemistry, Toxicity, Carcinogens, Female, Food Science
-
10
المؤلفون: Joseph H. Roycroft, Jeffrey A. Dill, Kathleen H. Mellinger, Kyeonghee Monica Lee, Derrick J. Bates, Leo T. Burka
المصدر: Toxicological Sciences. 77:6-18
مصطلحات موضوعية: medicine.medical_specialty, Pathology, Vanadium Compounds, Lung deposition, Vanadium, chemistry.chemical_element, Mice, Inbred Strains, Toxicology, Models, Biological, Mice, Internal medicine, Administration, Inhalation, medicine, Animals, Toxicokinetics, Pentoxide, Toxicity Tests, Chronic, Lung, Dose-Response Relationship, Drug, Inhalation, Chemistry, Organ Size, Rats, Inbred F344, Rats, medicine.anatomical_structure, Endocrinology, Concomitant, Female, Deposition (chemistry)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f75abd5ab23b374ca3f21cf297df46
https://doi.org/10.1093/toxsci/kfh005