المؤلفون: Todorova V; Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria., Savova MS; Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria., Ivanova S; Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria., Ivanov K; Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria., Georgiev MI; Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.

المصدر: Nutrients [Nutrients] 2023 Jul 07; Vol. 15 (13). Date of Electronic Publication: 2023 Jul 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Adipogenesis* , Leuzea*/chemistry, Humans ; Mice ; Animals ; Plant Extracts/chemistry ; Lipid Metabolism ; Lipolysis ; Lipids ; 3T3-L1 Cells

المؤلفون: Olennikov DN; Laboratory of Biomedical Research, Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Sakh'yanovoy Street 6, 670047 Ulan-Ude, Russia.

المصدر: Biomolecules [Biomolecules] 2022 Nov 20; Vol. 12 (11). Date of Electronic Publication: 2022 Nov 20.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Leuzea* , Asteraceae* , Lignans* , Triterpenes*, Ethnopharmacology ; Flavonoids

المؤلفون: Skała E; Department of Biology and Pharmaceutical Botany, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland., Olszewska MA; Department of Pharmacognosy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland., Makowczyńska J; Department of Biology and Pharmaceutical Botany, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland., Kicel A; Department of Pharmacognosy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 10; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Leuzea*, Biomass ; Flavonoids ; Sucrose

المؤلفون: Zhen D; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: dongzhen@imun.edu.cn., Liu C; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: 76526971@qq.com., Huang T; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: nmghtp@163.com., Fu D; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: fu_dan_ni@126.com., Bai X; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: bx_1226@163.com., Ma Q; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: maqq2020@126.com., Jiang M; Collage of Computer Science and Technology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: mingyangjiang@imun.edu.cn., Gong G; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: gongguohua0211@163.com.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2022 Oct 05; Vol. 296, pp. 115497. Date of Electronic Publication: 2022 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Acute Lung Injury*/chemically induced , Acute Lung Injury*/drug therapy , Acute Lung Injury*/metabolism , Asteraceae*/chemistry , Leuzea*/chemistry , Plant Extracts*/chemistry , Plant Extracts*/pharmacology , Plant Extracts*/therapeutic use, Animals ; Anti-Inflammatory Agents ; Ethanol ; Heme Oxygenase-1/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflorescence ; Interleukin-6/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Lipopolysaccharides/toxicity ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred BALB C ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Signal Transduction ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: Zheng Z; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Xian Y; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China; Department of Pharmacy, Xi'an NO.3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, Shaanxi 710018, PR China., Jin Z; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Yao F; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Liu Y; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Deng Y; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Wang B; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Chen D; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Yang J; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Ren L; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China., Lin R; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, No. 76 Yanta West Road, Xi'an, Shaanxi 710061, PR China. Electronic address: linrong@xjtu.edu.cn.

المصدر: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2022 Oct; Vol. 105, pp. 154197. Date of Electronic Publication: 2022 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

مواضيع طبية MeSH: Leuzea* , Myocardial Ischemia* , Sirtuins*, Animals ; Male ; Rats ; Adenosine Triphosphate ; Energy Metabolism ; NAD ; NF-E2-Related Factor 2 ; Oxidative Stress ; Rats, Sprague-Dawley ; Reactive Oxygen Species

المؤلفون: Afsharnezhad M; Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran., Shahangian SS; Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran., Rasti B; Department of Microbiology, Faculty of Basic Sciences, Lahijan Branch, Islamic Azad University (IAU), Lahijan, Guilan, Iran., Faezi Ghasemi M; Department of Microbiology, Faculty of Basic Sciences, Lahijan Branch, Islamic Azad University (IAU), Lahijan, Guilan, Iran.

المصدر: Iranian biomedical journal [Iran Biomed J] 2021 Jan; Vol. 25 (1), pp. 21-32. Date of Electronic Publication: 2020 Aug 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pasteur Institute of Iran Country of Publication: Iran NLM ID: 9814853 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2008-823X (Electronic) Linking ISSN: 1028852X NLM ISO Abbreviation: Iran Biomed J Subsets: MEDLINE

مواضيع طبية MeSH: Leuzea*, Enzyme Inhibitors/*pharmacology , Plant Extracts/*pharmacology, Acetone ; Alzheimer Disease/enzymology ; Anti-Bacterial Agents/pharmacology ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Cholinesterase Inhibitors/pharmacology ; Diabetes Mellitus/enzymology ; Enzyme Inhibitors/chemistry ; Ethanol ; Flavonoids/analysis ; Free Radical Scavengers/pharmacology ; Gram-Positive Bacteria/drug effects ; Humans ; Inhibitory Concentration 50 ; Methanol ; Oils, Volatile/analysis ; Phenols/analysis ; Plant Extracts/chemistry ; alpha-Amylases/antagonists & inhibitors

المؤلفون: Zughdani M; Department of Pharmacognosy, Faculty of Pharmacy, Near East University, Lefkoşa, Nicosia, 99138, N. Cyprus; The University of Elmergib, Faculty of Pharmacy, Department of Pharmacognosy, Libya., Yusufoğlu HS; Department of Pharmacognosy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia., Ekiz G; Near East University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Lefkoşa, Nicosia, Cyprus., Linden A; University of Zurich, Department of Chemistry, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Çalış İ; Department of Pharmacognosy, Faculty of Pharmacy, Near East University, Lefkoşa, Nicosia, 99138, N. Cyprus. Electronic address: icalis664@gmail.com.

المصدر: Phytochemistry [Phytochemistry] 2020 Dec; Vol. 180, pp. 112530. Date of Electronic Publication: 2020 Oct 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Ecdysteroids* , Leuzea*, Magnetic Resonance Spectroscopy ; Molecular Structure

المؤلفون: Skała E; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Muszyńskiego 1, 90-151, Łódź, Poland. ewa.skala@umed.lodz.pl., Kowalczyk T; Department of Genetics and Plant Molecular Biology and Biotechnology, The University of Łódź, Banacha 12/13, 90-237, Łódź, Poland., Toma M; Laboratory of Medical Genetics, University of Łódź, Pomorska 141/143, 90-236, Łódź, Poland., Szemraj J; Department of Medical Biochemistry, Medical University of Łódź, Mazowiecka 6/8, 92-215, Łódź, Poland., Radek M; Department of Neurosurgery, Surgery of Spine and Peripheral Nerves, Medical University of Łódź, University Hospital WAM-CSW, Łódź, Poland., Pytel D; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Hollings Cancer Center, HCC-709, 86 Jonathan Lucas Street, Charleston, SC, 29425, USA., Wieczfinska J; Department of Immunopathology, Chair of Allergology, Immunology and Dermatology, Faculty of Biomedical Sciences and Postgraduate Training, Medical University of Łódź, Żeligowskiego 7/9, 90-752, Łódź, Poland., Wysokińska H; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Muszyńskiego 1, 90-151, Łódź, Poland., Śliwiński T; Laboratory of Medical Genetics, University of Łódź, Pomorska 141/143, 90-236, Łódź, Poland., Sitarek P; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Muszyńskiego 1, 90-151, Łódź, Poland.

المصدر: Molecular and cellular biochemistry [Mol Cell Biochem] 2018 Aug; Vol. 445 (1-2), pp. 89-97. Date of Electronic Publication: 2017 Dec 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Brain Neoplasms/*pathology , Caspase 3/*metabolism , Caspase 9/*metabolism , Glioma/*pathology , Leuzea/*chemistry , Membrane Potential, Mitochondrial/*drug effects , Plant Extracts/*pharmacology , Plant Roots/*chemistry , Reactive Oxygen Species/*metabolism, Antineoplastic Agents, Phytogenic/pharmacology ; Brain Neoplasms/enzymology ; Brain Neoplasms/metabolism ; Caspase 3/genetics ; Caspase 9/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Enzyme Activation ; Glioma/enzymology ; Glioma/metabolism ; Humans ; Leuzea/growth & development ; Leuzea/metabolism ; Middle Aged ; Plant Roots/growth & development ; Plant Roots/metabolism ; Tumor Suppressor Protein p53/drug effects ; bcl-2-Associated X Protein/genetics

المؤلفون: Hu B; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: 839061084@qq.com., Zhen D; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: dongzhen@imun.edu.cn., Bai M; Key Laboratory of Mongolian Medicine Research and Development Engineering, Ministry of Education, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: baimeirong@126.com., Xuan T; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: 1543505206@qq.com., Wang Y; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: shen348@126.com., Liu M; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: lmjlwz@163.com., Yu L; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: tl_ylj@163.com., Bai D; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: 1605551902@qq.com., Fu D; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: biops2016@163.com., Wei C; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao, 028000, Inner Mongolia Autonomous Region, PR China. Electronic address: weichengxi1224@163.com.

المصدر: Journal of ethnopharmacology [J Ethnopharmacol] 2022 Apr 24; Vol. 288, pp. 114936. Date of Electronic Publication: 2022 Jan 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Cardiotoxicity/*prevention & control , Doxorubicin/*toxicity , Leuzea/*chemistry , Plant Extracts/*pharmacology, Animals ; Antibiotics, Antineoplastic/toxicity ; Apoptosis/drug effects ; Cardiotonic Agents/isolation & purification ; Cardiotonic Agents/pharmacology ; Cardiotoxicity/etiology ; Cell Line ; Ethanol/chemistry ; Female ; Male ; Mitochondrial Dynamics/drug effects ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/pathology ; Rats ; Tandem Mass Spectrometry ; Zebrafish

المؤلفون: Skała E; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Poland. ewa.skala@umed.lodz.pl., Sitarek P; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Poland., Toma M; Department of Molecular Genetics, University of Łódź, Poland., Szemraj J; Department of Medical Biochemistry, Medical University of Łódź, Poland., Radek M; Department of Neurosurgery and Peripheral Nerve Surgery, Medical University of Łódź, University Hospital WAM-CSW, Łódź, Poland., Nieborowska-Skorska M; Department of Microbiology and Immunology, Fels Institute for Cancer Research and Molecular Biology, Temple University, School of Medicine, Philadelphia, PA, USA., Skorski T; Department of Microbiology and Immunology, Fels Institute for Cancer Research and Molecular Biology, Temple University, School of Medicine, Philadelphia, PA, USA., Wysokińska H; Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Poland., Śliwiński T; Department of Molecular Genetics, University of Łódź, Poland.

المصدر: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2016 Nov; Vol. 68 (11), pp. 1454-1464. Date of Electronic Publication: 2016 Oct 02.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*pharmacology , Brain Neoplasms/*drug therapy , Cell Proliferation/*drug effects , Glioma/*drug therapy , Leuzea/*chemistry , Plant Extracts/*pharmacology , Plant Roots/*chemistry , Proto-Oncogene Proteins c-bcl-2/*metabolism , Tumor Suppressor Protein p53/*metabolism , bcl-2-Associated X Protein/*metabolism, Agrobacterium/physiology ; Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Blotting, Western ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Cell Cycle Checkpoints/drug effects ; Dose-Response Relationship, Drug ; Glioma/genetics ; Glioma/metabolism ; Glioma/pathology ; Leuzea/microbiology ; Membrane Potential, Mitochondrial/drug effects ; Microscopy, Fluorescence ; Phytotherapy ; Plant Extracts/isolation & purification ; Plant Roots/microbiology ; Plants, Medicinal ; Proto-Oncogene Proteins c-bcl-2/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/drug effects ; Transformation, Bacterial ; Tumor Suppressor Protein p53/genetics ; bcl-2-Associated X Protein/genetics