نتائج البحث - "Liane Dupont"

1

Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern

المصدر: Nature Microbiology
Dupont, L, Snell, L B, Graham, C, Seow, J, Merrick, B, Lechmere, T, Maguire, T J A, Hallett, S R, Pickering, S, Charalampous, T, Alcolea-Medina, A, Huettner, I, Jimenez-Guardeño, J M, Acors, S, Almeida, N, Cox, D, Dickenson, R E, Galao, R P, Kouphou, N, Lista, M J, Ortega-Prieto, A M, Wilson, H, Winstone, H, Fairhead, C, Su, J Z, Nebbia, G, Batra, R, Neil, S, Shankar-Hari, M, Edgeworth, J D, Malim, M H & Doores, K J 2021, ' Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern ', Nature Microbiology, vol. 6, no. 11, pp. 1433-1442 . https://doi.org/10.1038/s41564-021-00974-0

مصطلحات موضوعية: Microbiology (medical), Adult, Male, COVID-19 Vaccines, Immunology, Alpha (ethology), Applied Microbiology and Biotechnology, Microbiology, Neutralization, Immunoglobulin G, Virus, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Antibodies, Viral/blood, Neutralization Tests, SARS-CoV-2/genetics, Genetics, Humans, Neutralizing antibody, Antibodies, Neutralizing/blood, 030304 developmental biology, Aged, Aged, 80 and over, 0303 health sciences, biology, SARS-CoV-2, Vaccination, Immunization, Passive, Cell Biology, Middle Aged, Virology, 3. Good health, COVID-19/immunology, Spike Glycoprotein, Coronavirus/genetics, Immunoglobulin M, Viral infection, Mutation, biology.protein, Female, Antibody, 030217 neurology & neurosurgery

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5faf396a883d2efccb60cc07135362b
http://europepmc.org/articles/PMC8556155

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2

Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study

المؤلفون: Jennifer Vidler, Shubhankar Sinha, Helen Kakkassery, Jack Cooper, Thanussuyah Alaguthurai, Thomas Hayday, Ana Montes, Yin Wu, Puay Ling Lee, Shraddha Kamdar, Leticia Monin, Muhammad Shamim Khan, Rosalind Graham, Daniel Davies, Maria Conde Poole, Miguel Muñoz-Ruiz, Adam Laing, Charlotte O'Brien-Gore, Sheeba Irshad, Sophie Papa, Anne Rigg, Elizabeth Harvey-Jones, Piers E.M. Patten, Magdalene Joseph, Paul Fields, Clara Domingo-Vila, Mark Harries, Francesca Di Rosa, Jeffrey Seow, Richard Davis, Adrian Hayday, Katie J. Doores, Duncan R. McKenzie, Isaac Francos Quijorna, Josephine Eum, Angela Swampillai, Timothy Tree, Bernard V. North, Liane Dupont, James Spicer, Michael H. Malim, Sultan Abdul-Jawad, Carl Graham, Irene del Molino del Barrio

المصدر: Lancet oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7e59dcd46956cf15585304c1e9092d
https://doi.org/10.1016/s1470-2045(21)00213-8

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3

Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter

المؤلفون: Liane Dupont, Megan McIntosh, Madeleine Poulter, Lily Du, Matthew B. Reeves, Stephanie Choi

المساهمون: Dupont, Liane [0000-0002-2124-4069], Apollo - University of Cambridge Repository

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Cytomegalovirus, Biochemistry, epigenetic regulation, chromatin modification, 03 medical and health sciences, herpesvirus, cell signaling, Humans, Histone acetyltransferase activity, Gene Regulation, lysine acetyltransferase 6A (KAT6A), Src family kinase, Promoter Regions, Genetic, Protein kinase A, Molecular Biology, Cells, Cultured, Histone Acetyltransferases, 030102 biochemistry & molecular biology, biology, Chemistry, histone acetylation, phosphoproteomics, Zinc Fingers, Cell Biology, Histone acetyltransferase, 3. Good health, Cell biology, Chromatin, hematopoietic cell kinase, src-Family Kinases, 030104 developmental biology, Histone phosphorylation, Histone, cytomegalovirus reactivation, gene expression, biology.protein, Virus Activation

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71275f7a5ac69b3ccbbf34c8db479f6f
https://doi.org/10.1074/jbc.ra119.009667

4

Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections

المصدر: medRxiv
article-version (status) pre
article-version (number) 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73de8e732926f902875f67eac533c570
http://europepmc.org/articles/PMC8202432

5

Interim results of the safety and immune-efficacy of 1 versus 2 doses of COVID-19 vaccine BNT162b2 for cancer patients in the context of the UK vaccine priority guidelines

مصطلحات موضوعية: education.field_of_study, medicine.medical_specialty, business.industry, Population, Cancer, Context (language use), Immune dysregulation, medicine.disease_cause, medicine.disease, Vaccine efficacy, Herd immunity, Vaccination, Internal medicine, Medicine, Seroconversion, business, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f306c775f6a44fc6cb777201f33ee31d
https://doi.org/10.1101/2021.03.17.21253131

6

Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6

المؤلفون: Callum Talbot-Cooper, Yongxu Lu, Liane Dupont, Brian J. P. Huntly, Geoffrey L. Smith, Jennifer H. Stuart, Shuchi Agrawal-Singh, Joseph S. Snowden, Andrei I. Smid

المساهمون: Lu, Yongxu [0000-0003-4701-5560], Smid, Andrei I [0000-0001-9732-0059], Snowden, Joseph S [0000-0001-7857-0634], Smith, Geoffrey L [0000-0002-3730-9955], Apollo - University of Cambridge Repository

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, STAT2 recruitment, viruses, Vaccinia virus, Herpesvirus 1, Human, Virus Replication, medicine.disease_cause, Microbiology, Histone Deacetylases, Virus, Cell Line, type I interferon signaling, Viral Proteins, 03 medical and health sciences, 0302 clinical medicine, Interferon, Cell Line, Tumor, Vaccinia, vaccinia virus protein C6, medicine, Humans, STAT2, immune evasion, Histone deacetylase 5, Multidisciplinary, biology, Chemistry, HDAC11, DNA Viruses, histone deactylase 4, Biological Sciences, HDAC4, HDAC1, 3. Good health, Cell biology, Repressor Proteins, HEK293 Cells, 030104 developmental biology, Herpes simplex virus, PNAS Plus, 030220 oncology & carcinogenesis, Interferon Type I, biology.protein, HeLa Cells, Signal Transduction, medicine.drug

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18abd67d3939b3fe8a1323591374e449
https://doi.org/10.1073/pnas.1816399116

7

The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

المؤلفون: Sergio Martínez Cuesta, Paul J. Lehner, Liane Dupont, Stefan G. Sarafianos, Edward J. D. Greenwood, Ana Teixeira-Silva, Nicholas J Matheson, James C Williamson, Adi Naamati, Stuart Bloor, Raven Shah

المساهمون: Dupont, Liane [0000-0002-2124-4069], Williamson, James [0000-0002-2009-189X], Greenwood, Edward [0000-0002-5224-0263], Matheson, Nicholas [0000-0002-3318-1851], Lehner, Paul [0000-0001-9383-1054], Apollo - University of Cambridge Repository

المصدر: Cell hostmicrobe. 29(5)

مصطلحات موضوعية: Chromosomal Proteins, Non-Histone, viruses, Ubiquitin-Protein Ligases, Virus Integration, ATAC-seq, Cell Cycle Proteins, HIV Infections, Biology, Vpr, SMC5-SMC6 complex, Virus Replication, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Virology, Complementary DNA, Extrachromosomal DNA, Gene expression, Smc5-Smc6 complex, Gene silencing, Humans, 030304 developmental biology, chromatin compaction, 0303 health sciences, unintegrated lentivirus, virus diseases, vpr Gene Products, Human Immunodeficiency Virus, biochemical phenomena, metabolism, and nutrition, Nuclear DNA, Chromatin, Cell biology, viral gene silencing, SLF2, Host-Pathogen Interactions, HIV-1, Parasitology, CRISPR-Cas9 knockout screen, 030217 neurology & neurosurgery

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab28e1bb3ff7f4d6f71903c5fc9aa2c
https://pubmed.ncbi.nlm.nih.gov/33811831

8

Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant

المساهمون: Medical Microbiology and Infection Prevention, AII - Infectious diseases

المصدر: Immunity, 54(6), 1276-1289.e6. Cell Press
Immunity
Graham, C, Seow, J, Huettner, I, Khan, H, Kouphou, N, Acors, S, Winstone, H, Pickering, S, Galao, R P, Dupont, L, Lista, M J, Jimenez-Guardeño, J M, Laing, A G, Wu, Y, Joseph, M, Muir, L, van Gils, M J, Ng, W M, Duyvesteyn, H M E, Zhao, Y, Bowden, T A, Shankar-Hari, M, Rosa, A, Cherepanov, P, McCoy, L E, Hayday, A C, Neil, S J D, Malim, M H & Doores, K J 2021, ' Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant ', Immunity, vol. 54, no. 6, pp. 1276-1289.e6 . https://doi.org/10.1016/j.immuni.2021.03.023

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, COVID-19/diagnosis, Protein Conformation, Antibodies, Viral, Epitopes/chemistry, Neutralization, Epitope, Epitopes, 0302 clinical medicine, antibody, Antibodies, Viral/chemistry, Immunology and Allergy, Protein Binding/immunology, biology, Antibodies, Monoclonal, Antibodies, Neutralizing/immunology, neutralizing epitope, Infectious Diseases, Angiotensin-Converting Enzyme 2/chemistry, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, Angiotensin-Converting Enzyme 2, Antibody, variant of concern, Protein Binding, Antigenicity, Subdominant, medicine.drug_class, Immunology, Antibodies, Monoclonal/chemistry, Cross Reactions, Monoclonal antibody, SARS-CoV-2/immunology, Article, Antigenic drift, Structure-Activity Relationship, 03 medical and health sciences, Neutralization Tests, Viral entry, medicine, Humans, B.1.1.7, Spike Glycoprotein, Coronavirus/chemistry, SARS-CoV-2, immune escape, COVID-19, neutralization, Antibodies, Neutralizing, Virology, 030104 developmental biology, Mutation, biology.protein, Cross Reactions/immunology