المؤلفون: Libardo MDJ; Discovery Biology, Infectious Diseases & Vaccines, Merck & Co., Inc., West Point, PA 19486, USA., Durr E; Discovery Biology, Infectious Diseases & Vaccines, Merck & Co., Inc., West Point, PA 19486, USA., Hernandez LD; Discovery Biology, Infectious Diseases & Vaccines, Merck & Co., Inc., West Point, PA 19486, USA.

المصدر: Methods and protocols [Methods Protoc] 2023 Apr 07; Vol. 6 (2). Date of Electronic Publication: 2023 Apr 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101720073 Publication Model: Electronic Cited Medium: Internet ISSN: 2409-9279 (Electronic) Linking ISSN: 24099279 NLM ISO Abbreviation: Methods Protoc Subsets: PubMed not MEDLINE

المؤلفون: Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Duncombe CJ; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Green SR; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Wyatt PG; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Thompson S; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Ray PC; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Ioerger TR; Department of Computer Science and Engineering, Texas A&M University, College Station, TX 77843, USA., Oh S; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Goodwin MB; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Barry CE 3rd; Tuberculosis Research Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7935, South Africa. Electronic address: cbarry@niaid.nih.gov.

المصدر: Cell chemical biology [Cell Chem Biol] 2021 Aug 19; Vol. 28 (8), pp. 1180-1191.e20. Date of Electronic Publication: 2021 Mar 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents/*pharmacology , Drug Resistance, Bacterial/*drug effects , Indoles/*pharmacology , Mycobacterium tuberculosis/*drug effects , Tryptophan/*biosynthesis, Animals ; Antitubercular Agents/chemistry ; Antitubercular Agents/metabolism ; Dose-Response Relationship, Drug ; Indoles/chemistry ; Indoles/metabolism ; Mice ; Microbial Sensitivity Tests ; Models, Molecular ; Molecular Structure ; Mycobacterium bovis/drug effects ; Mycobacterium bovis/metabolism ; Mycobacterium tuberculosis/metabolism

المؤلفون: Comert F; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA., Heinrich F; Department of Physics, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA., Chowdhury A; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA., Schoeneck M; University of Rochester School of Medicine and Dentistry, Rochester, NY, 14620, USA., Darling C; Department of Biological Sciences, Clemson University, Clemson, SC, 29634, USA., Anderson KW; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA.; Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA., Libardo MDJ; Department of Chemistry and Institute of Materials Science, University of Connecticut, Storrs, CT, 06269, USA., Angeles-Boza AM; Department of Chemistry and Institute of Materials Science, University of Connecticut, Storrs, CT, 06269, USA., Silin V; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA., Cotten ML; Department of Applied Science, William and Mary, Williamsburg, VA, 23185, USA. mcotten@wm.edu., Mihailescu M; Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA. emihailescu@ibbr.umd.edu.

المصدر: Scientific reports [Sci Rep] 2021 Jun 16; Vol. 11 (1), pp. 12620. Date of Electronic Publication: 2021 Jun 16.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Cell-Penetrating Peptides/*pharmacology , Copper/*chemistry , Lipid Bilayers/*chemistry, A549 Cells ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell-Penetrating Peptides/chemistry ; Fish Proteins/chemistry ; Fish Proteins/pharmacology ; HeLa Cells ; Humans ; Lipid Peroxidation ; Models, Molecular

المؤلفون: Portelinha J; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States., Duay SS; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States.; Chemistry Department, Adamson University, 900 San Marcelino Street, Ermita, Manila 1000, Philippines., Yu SI; Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, Connecticut 06269, United States., Heilemann K; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States., Libardo MDJ; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States., Juliano SA; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States., Klassen JL; Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, Connecticut 06269, United States., Angeles-Boza AM; Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States.; Institute of Material Science, University of Connecticut, 55 North Eagleville Road, Storrs, Connecticut 06269, United States.

المصدر: Chemical reviews [Chem Rev] 2021 Feb 24; Vol. 121 (4), pp. 2648-2712. Date of Electronic Publication: 2021 Feb 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985134R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6890 (Electronic) Linking ISSN: 00092665 NLM ISO Abbreviation: Chem Rev Subsets: MEDLINE

مواضيع طبية MeSH: Copper/*chemistry , Copper/*metabolism , Pore Forming Cytotoxic Proteins/*chemistry , Pore Forming Cytotoxic Proteins/*pharmacology, Animals ; Cations, Divalent ; Humans ; Pore Forming Cytotoxic Proteins/immunology ; Pore Forming Cytotoxic Proteins/metabolism ; Protein Domains

المؤلفون: Oh S; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Azeeza S; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Pauly GT; Chemical Biology Laboratory, National Cancer Institute, Frederick, Maryland 21702, United States., Roma JSO; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Sajid A; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Tateishi Y; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Duncombe C; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Goodwin M; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Ioerger TR; Department of Computer Science and Engineering, Texas A&M University, College Station, Texas 77843, United States., Wyatt PG; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Ray PC; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Gray DW; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Barry CE 3rd; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.; Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7935, South Africa.

المصدر: ACS infectious diseases [ACS Infect Dis] 2021 Feb 12; Vol. 7 (2), pp. 479-492. Date of Electronic Publication: 2021 Jan 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents*/pharmacology , Mycobacterium tuberculosis*/genetics, High-Throughput Screening Assays ; Structure-Activity Relationship

المؤلفون: Thomas SE; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Whitehouse AJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Brown K; University of Cambridge Molecular Immunity Unit, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge CB2 0AY, UK., Burbaud S; University of Cambridge Molecular Immunity Unit, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Belardinelli JM; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA., Sangen J; University of Cambridge Molecular Immunity Unit, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Lahiri R; National Hansen's Disease Program, Healthcare Systems Bureau, Health Resources and Services Administration, Department of Health and Human Services, Baton Rouge, LA, USA., Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA., Gupta P; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Malhotra S; Birkbeck College, University of London, Malet Street WC1E7HX, UK., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA., Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA., Abell C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Coyne AG; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Blundell TL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Floto RA; University of Cambridge Molecular Immunity Unit, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge CB2 0AY, UK., Mendes V; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.

المصدر: Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 8099-8112.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Bacterial Proteins/*antagonists & inhibitors , Enzyme Inhibitors/*pharmacology , RNA, Transfer/*metabolism , tRNA Methyltransferases/*antagonists & inhibitors, Anti-Bacterial Agents/chemistry ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Binding Sites ; Drug Discovery/methods ; Enzyme Inhibitors/chemistry ; Molecular Docking Simulation ; Mycobacterium abscessus/drug effects ; Mycobacterium abscessus/enzymology ; Mycobacterium leprae/drug effects ; Mycobacterium leprae/enzymology ; Protein Binding ; tRNA Methyltransferases/chemistry ; tRNA Methyltransferases/metabolism

المؤلفون: Whitehouse AJ; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Kasbekar M; National Center for Advancing Translational Sciences , National Institutes of Health , Bethesda , Maryland 20850 , United States., Brear PD; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge , CB2 1GA , U.K., Fischer G; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge , CB2 1GA , U.K., Thomas CJ; National Center for Advancing Translational Sciences , National Institutes of Health , Bethesda , Maryland 20850 , United States., Barry CE 3rd; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Coyne AG; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Abell C; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Dec 12; Vol. 62 (23), pp. 10586-10604. Date of Electronic Publication: 2019 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Antitubercular Agents/*chemistry , Antitubercular Agents/*pharmacology , Fumarate Hydratase/*antagonists & inhibitors , Mycobacterium tuberculosis/*drug effects, Binding Sites ; Fumarate Hydratase/metabolism ; Humans ; Models, Molecular ; Molecular Structure ; Mycobacterium tuberculosis/enzymology ; Protein Conformation ; Structure-Activity Relationship

المؤلفون: Whitehouse AJ; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Thomas SE; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge CB2 1GA , U.K., Brown KP; Molecular Immunity Unit, Department of Medicine, MRC Laboratory of Molecular Biology , University of Cambridge , Francis Crick Avenue, Cambridge Biomedical Campus , Cambridge CB2 0QH , U.K.; Cambridge Centre for Lung Infection , Royal Papworth Hospital , Cambridge CB23 3RE , U.K., Fanourakis A; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Chan DS; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease , National Institutes of Health , 9000 Rockville Pike , Bethesda, Maryland 20892 , United States., Mendes V; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge CB2 1GA , U.K., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease , National Institutes of Health , 9000 Rockville Pike , Bethesda, Maryland 20892 , United States., Floto RA; Molecular Immunity Unit, Department of Medicine, MRC Laboratory of Molecular Biology , University of Cambridge , Francis Crick Avenue, Cambridge Biomedical Campus , Cambridge CB2 0QH , U.K.; Cambridge Centre for Lung Infection , Royal Papworth Hospital , Cambridge CB23 3RE , U.K., Abell C; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Blundell TL; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge CB2 1GA , U.K., Coyne AG; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Aug 08; Vol. 62 (15), pp. 7210-7232. Date of Electronic Publication: 2019 Jul 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*chemistry , Drug Development/*methods , Escherichia coli Proteins/*antagonists & inhibitors , Escherichia coli Proteins/*metabolism , Mycobacterium abscessus/*drug effects , Mycobacterium abscessus/*enzymology , tRNA Methyltransferases/*antagonists & inhibitors , tRNA Methyltransferases/*metabolism, Anti-Bacterial Agents/pharmacology ; Crystallography, X-Ray/methods ; Humans ; Protein Structure, Secondary

المؤلفون: Libardo MDJ; Department of Chemistry , University of Connecticut , 55 N. Eagleville Road , Storrs , Connecticut 06269 , United States., de la Fuente-Nuñez C; Synthetic Biology Group, MIT Synthetic Biology Center, Department of Biological Engineering, and Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , 21 Ames Street , Cambridge , Massachusetts 02139 , United States.; Research Laboratory of Electronics , Massachusetts Institute of Technology , 50 Vassar Street , Cambridge , Massachusetts 02139 , United States.; The Broad Institute of MIT and Harvard , 415 Main Street , Cambridge , Massachusetts 02139 , United States., Anand K; Department of Microbiology and Cell Biology, Center for Infectious Disease Research , Indian Institute of Science , Bangalore 560012 , India., Krishnamoorthy G; Department of Immunology , Max Planck Institute for Infection Biology , Virchowweg 12 , Berlin 10117 , Germany., Kaiser P; Department of Immunology , Max Planck Institute for Infection Biology , Virchowweg 12 , Berlin 10117 , Germany., Pringle SC; The Ragon Institute of Harvard, MIT, and Massachusetts General Hospital , 400 Technology Square , Cambridge , Massachusetts 02139 , United States., Dietz C; Department of Chemistry , University of Connecticut , 55 N. Eagleville Road , Storrs , Connecticut 06269 , United States., Pierce S; Department of Chemistry , University of Connecticut , 55 N. Eagleville Road , Storrs , Connecticut 06269 , United States., Smith MB; Department of Chemistry , University of Connecticut , 55 N. Eagleville Road , Storrs , Connecticut 06269 , United States., Barczak A; The Ragon Institute of Harvard, MIT, and Massachusetts General Hospital , 400 Technology Square , Cambridge , Massachusetts 02139 , United States.; Division of Infectious Disease , Massachusetts General Hospital , 55 Fruit Street , Boston , Massachusetts 02114 , United States.; Department of Medicine , Harvard Medical School , 25 Shattuck Street , Boston , Massachusetts 02115 , United States., Kaufmann SHE; Department of Immunology , Max Planck Institute for Infection Biology , Virchowweg 12 , Berlin 10117 , Germany., Singh A; Department of Microbiology and Cell Biology, Center for Infectious Disease Research , Indian Institute of Science , Bangalore 560012 , India., Angeles-Boza AM; Department of Chemistry , University of Connecticut , 55 N. Eagleville Road , Storrs , Connecticut 06269 , United States.; Institute of Materials Science , University of Connecticut , 97 N. Eagleville Road , Storrs , Connecticut 06269 , United States.

المصدر: ACS infectious diseases [ACS Infect Dis] 2018 Nov 09; Vol. 4 (11), pp. 1623-1634. Date of Electronic Publication: 2018 Sep 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Chelating Agents/*pharmacology , Copper/*chemistry , Mycobacterium tuberculosis/*drug effects , Peptides/*pharmacology , Phagosomes/*chemistry, Animals ; Anti-Bacterial Agents/pharmacology ; Chelating Agents/chemistry ; Host-Pathogen Interactions ; Macrophages/microbiology ; Mice ; Oxidation-Reduction ; Oxidative Stress ; Peptides/chemistry ; Proof of Concept Study ; RAW 264.7 Cells ; Tuberculosis/microbiology

المؤلفون: Libardo MDJ; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Bahar AA; Department of Biomedical and Chemical Engineering, Syracuse University, NY, USA., Ma B; Basic Science Program, Leidos Biomedical Research, Inc. Cancer and Inflammation Program, National Cancer Institute, Frederick, MD, USA., Fu R; National High Magnetic Field Laboratory, Tallahassee, FL, USA., McCormick LE; Hamilton College, Department of Chemistry, Clinton, NY, USA., Zhao J; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD, USA., McCallum SA; Rennselaer Polytechnic Institute, Center for Biotechnology & Interdisciplinary Studies, Troy, NY, USA., Nussinov R; Basic Science Program, Leidos Biomedical Research, Inc. Cancer and Inflammation Program, National Cancer Institute, Frederick, MD, USA.; Sackler Institute of Molecular Medicine, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Israel., Ren D; Department of Biomedical and Chemical Engineering, Syracuse University, NY, USA.; Syracuse Biomaterials Institute, Syracuse University, NY, USA.; Department of Civil and Environmental Engineering, Syracuse University, NY, USA.; Department of Biology, Syracuse University, NY, USA., Angeles-Boza AM; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Cotten ML; Department of Applied Science, College of William and Mary, Williamsburg, VA, USA.

المصدر: The FEBS journal [FEBS J] 2017 Nov; Vol. 284 (21), pp. 3662-3683. Date of Electronic Publication: 2017 Sep 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Antimicrobial Cationic Peptides/*metabolism , Biofilms/*drug effects , Escherichia coli/*drug effects , Fish Proteins/*metabolism , Pseudomonas aeruginosa/*drug effects , Staphylococcus aureus/*drug effects, Animals ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/metabolism ; Antimicrobial Cationic Peptides/isolation & purification ; DNA Cleavage/drug effects ; Escherichia coli/cytology ; Escherichia coli/growth & development ; Fish Proteins/isolation & purification ; Fishes ; Microbial Sensitivity Tests ; Molecular Dynamics Simulation ; Pseudomonas aeruginosa/cytology ; Pseudomonas aeruginosa/growth & development ; Staphylococcus aureus/cytology ; Staphylococcus aureus/growth & development