المؤلفون: Morozko, EL, Smith-Geater, C, Monteys, AM, Pradhan, S, Lim, RG, Langfelder, P, Kachemov, M, Kulkarni, JA, Zaifman, J, Hill, A, Stocksdale, JT, Cullis, PR, Wu, J, Ochaba, J, Miramontes, R, Chakraborty, A, Hazral, TK, Laub, A, St-Cyrc, S, Orellanam, I, Kopan, L, Wang, KQ, Yeung, S, Leavitt, BR, Reidling, JC, Yang, XW, Steffan, JS, Davidson, BL, Sarkar, PS, Thompson, LM

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 32

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::09985a4ebf37235f513250eff78dfb8c
https://escholarship.org/uc/item/3qr022ts

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المؤلفون: Fote GM; Department of Biological Chemistry, UC Irvine School of Medicine, Irvine, CA 92697.; Department of Neurological Surgery, UC Irvine School of Medicine, Orange, CA 92868., Eapen VV; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.; Casma Therapeutics, Cambridge, MA 02139., Lim RG; The University of California Irvine Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697., Yu C; Department of Physiology and Biophysics, University of California, Irvine, CA 92697., Salazar L; Department of Psychiatry and Human Behavior, UC Irvine School of Medicine, Orange, CA 92868., McClure NR; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697., McKnight J; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697., Nguyen TB; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697., Heath MC; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697., Lau AL; Department of Psychiatry and Human Behavior, UC Irvine School of Medicine, Orange, CA 92868., Villamil MA; Department of Biological Chemistry, UC Irvine School of Medicine, Irvine, CA 92697., Miramontes R; Department of Psychiatry and Human Behavior, UC Irvine School of Medicine, Orange, CA 92868., Kratter IH; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158.; Stanford Brain Stimulation Lab, Stanford, CA 94304.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94304., Finkbeiner S; Center for Systems and Therapeutics, Gladstone Institutes, San Francisco, CA 94158.; Department of Physiology, University of California, San Francisco, CA 94158.; Department of Neurology, University of California, San Francisco, CA 94158., Reidling JC; The University of California Irvine Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697., Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115., Kaiser P; Department of Biological Chemistry, UC Irvine School of Medicine, Irvine, CA 92697., Huang L; Department of Physiology and Biophysics, University of California, Irvine, CA 92697., Housman DE; Koch Institute for Integrative Cancer Research, The Massachusetts Institute of Technology, Cambridge, MA 02139., Thompson LM; Department of Biological Chemistry, UC Irvine School of Medicine, Irvine, CA 92697.; The University of California Irvine Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.; Department of Psychiatry and Human Behavior, UC Irvine School of Medicine, Orange, CA 92868.; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697.; Center for Epigenetics and Metabolism, University of California, Irvine School of Medicine, University of California, Irvine, CA 92697., Steffan JS; The University of California Irvine Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.; Department of Psychiatry and Human Behavior, UC Irvine School of Medicine, Orange, CA 92868.; Center for Epigenetics and Metabolism, University of California, Irvine School of Medicine, University of California, Irvine, CA 92697.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Aug 06; Vol. 121 (32), pp. e2319091121. Date of Electronic Publication: 2024 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Huntingtin Protein*/metabolism , Huntingtin Protein*/genetics , Lysosomes*/metabolism , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Ubiquitin*/metabolism , Mitochondria*/metabolism, Humans ; Autophagy ; Animals ; Mitochondrial Proteins/metabolism ; Mitochondrial Proteins/genetics ; Mice ; Protein Binding ; Huntington Disease/metabolism ; Huntington Disease/genetics ; Huntington Disease/pathology ; Peptides/metabolism