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المؤلفون: Matthew R. Redinbo, Steven A. Kliewer, Linda B. Moore, Sompop Bencharit, Li Peng, Jillian Orans, Yu Xue
المصدر: Molecular Endocrinology. 21:1028-1038
مصطلحات موضوعية: Models, Molecular, Receptors, Steroid, Protein Conformation, medicine.medical_treatment, Biology, Crystallography, X-Ray, digestive system, Steroid, chemistry.chemical_compound, Endocrinology, Constitutive androstane receptor, medicine, Animals, Humans, Progesterones, Amino Acid Sequence, Amino Acids, Receptor, Molecular Biology, Pregnane X receptor, Estradiol, Ligand, Estrogen Receptor alpha, Pregnane X Receptor, General Medicine, Metabolism, digestive system diseases, chemistry, Biochemistry, Mutagenesis, Xenobiotic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab441eaf79e2026d20e31efe4f5f8ccd
https://doi.org/10.1210/me.2006-0323 -
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المؤلفون: Olivia R. R. Ittoop, Hongbing Wang, G. Bruce Wisely, Virginia E. Carnahan, Tom Luntz, Julie B. Stimmel, Linda B. Moore, Schroeder M. Noble, Paula R. Davis-Searles, Edward L. LeCluyse, Ashutosh Tripathy, Donald P. McDonnell, Ryan E. Watkins, Matthew R. Redinbo
المصدر: Biochemistry. 45:8579-8589
مصطلحات موضوعية: Receptors, Steroid, Receptors, Cytoplasmic and Nuclear, Biology, Ligands, Biochemistry, Article, Nuclear Receptor Coactivator 1, Constitutive androstane receptor, Humans, Nuclear receptor co-repressor 1, Histone Acetyltransferases, Pregnane X receptor, Retinoid X Receptor alpha, Retinoid X receptor alpha, Pregnane X Receptor, Tryptophan, DNA, Protein Structure, Tertiary, Nuclear receptor coactivator 1, Nuclear receptor, Nuclear receptor coactivator 3, Nuclear receptor coactivator 2, Biophysics, Dimerization, Ultracentrifugation, Transcription Factors
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المؤلفون: Jon D. Williams, Millard H. Lambert, Bruce Wisely, Robert X. Xu, John T. Moore, Linda B. Moore, Gregory M. Waitt, Erin N. Warren, Timothy M. Willson, Jon L. Collins, Emily E. Weinert
المصدر: Molecular Cell. 16(6):919-928
مصطلحات موضوعية: Binding Sites, Retinoid X Receptor alpha, Receptors, Cytoplasmic and Nuclear, Cell Biology, Biology, Retinoid X receptor, Ligand (biochemistry), Ligands, DNA-binding protein, Protein Structure, Tertiary, Thiazoles, Nuclear receptor, Biochemistry, Transcription (biology), Constitutive androstane receptor, Oximes, Biophysics, Inverse agonist, Humans, Receptor, Dimerization, Molecular Biology, Constitutive Androstane Receptor, Transcription Factors
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المؤلفون: Julie B. Stimmel, H. Eric Xu, Valerie G. Montana, Linda B. Moore, Millard H. Lambert, Steven G. Blanchard, Thomas B. Stanley, Cristin M. Galardi, Jason A. Holt, Lisa M. Leesnitzer
المصدر: Biochemistry. 42:9278-9287
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Amino Acid Motifs, Receptors, Cytoplasmic and Nuclear, Peroxisome proliferator-activated receptor, Biology, Crystallography, X-Ray, Ligands, Transfection, Biochemistry, Fluorescence, Mediator, Two-Hybrid System Techniques, Coactivator, medicine, Humans, Nuclear Receptor Co-Repressor 1, Protein Isoforms, Gene silencing, Nuclear Receptor Co-Repressor 2, Retinoid, Receptor, Oxazoles, Cells, Cultured, chemistry.chemical_classification, Binding Sites, Molecular Structure, Nuclear Proteins, Peptide Fragments, Protein Structure, Tertiary, DNA-Binding Proteins, Repressor Proteins, chemistry, Nuclear receptor, Tyrosine, Corepressor, hormones, hormone substitutes, and hormone antagonists, Transcription Factors
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المؤلفون: Millard H. Lambert, Randy K. Bledsoe, Boggs Sharon Davis, Jason Nichols, Shawn P. Williams, John T. Moore, Jon L. Collins, Timothy M. Willson, Ann B. Miller, David D. McKee, Michael A. Watson, Derek J. Parks, Linda B. Moore, Bruce Wisely
المصدر: Journal of Biological Chemistry. 278:27138-27143
مصطلحات موضوعية: Indole test, Hydrogen bond, Ligand, Stereochemistry, Tryptophan, Cell Biology, Ring (chemistry), Biochemistry, chemistry.chemical_compound, chemistry, Imidazole, Liver X receptor, Molecular Biology, Histidine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1b805b51c3cf75b118fcd22e4f6f97c8
https://doi.org/10.1074/jbc.m302260200 -
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المؤلفون: Elizabeth J. Beaudet, Ron Laethem, Steven J. Novick, Zhiyang Zhao, Thomas A. Brodie, Debie J. Hoivik, Andrews Robert Carl, Timothy K. Tippin, Edward L. LeCluyse, J. David Becherer, Jürgen M. Lehmann, Linda B. Moore, Darryl L. McDougald, Summer Jolley, Steven A. Kliewer, Michael D. Gaul, G. Hamilton, Kathy Mellon-Kusibab
المصدر: Drug Metabolism and Disposition. 31:870-877
مصطلحات موضوعية: Male, Receptors, Steroid, Matrix metalloproteinase inhibitor, Cell Culture Techniques, Drug Evaluation, Preclinical, Administration, Oral, Aminopyridines, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, ADAM17 Protein, Matrix Metalloproteinase Inhibitors, chemistry.chemical_compound, In vivo, medicine, Animals, Cytochrome P-450 CYP3A, Humans, Rats, Wistar, Enzyme inducer, Pharmacology, chemistry.chemical_classification, Pregnane X receptor, Dose-Response Relationship, Drug, Formamides, biology, Pregnane, Pregnane X Receptor, Metalloendopeptidases, Oxidoreductases, N-Demethylating, Dipeptides, Amides, Molecular biology, Matrix Metalloproteinases, Rats, ADAM Proteins, Thiazoles, medicine.anatomical_structure, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, Enzyme Induction, Hepatocyte, Hepatocytes, biology.protein, Drug Evaluation, Aryl Hydrocarbon Hydroxylases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728180f659f051cfc4b785f829bf565b
https://doi.org/10.1124/dmd.31.7.870 -
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المؤلفون: Dana R Hohman, Lisa A. Orband-Miller, Susan L. Weaver, Eugene L. Stewart, Shawn P. Williams, John T. Moore, Thomas G. Consler, Paul Kenneth Spearing, Ning Go, Philip Stewart Turnbull, Millard H. Lambert, Ron L. Hale, Linda B. Moore, Stacey A. Jones, Amy T. Lu, Brad R. Henke, G. Bruce Wisely, Jean Shearin, R. Graham Robinett
المصدر: Journal of Medicinal Chemistry. 45:5492-5505
مصطلحات موضوعية: Models, Molecular, endocrine system, Transcription, Genetic, Estrogen receptor, Crystallography, X-Ray, Ligands, Partial agonist, Radioligand Assay, Structure-Activity Relationship, Genes, Reporter, Drug Discovery, Tumor Cells, Cultured, polycyclic compounds, Estrogen Receptor beta, Humans, Structure–activity relationship, Receptor, reproductive and urinary physiology, Estrogen receptor beta, Triazines, Chemistry, Ligand binding assay, Estrogen Receptor alpha, Stereoisomerism, Antiestrogen, Receptors, Estrogen, Biochemistry, Molecular Medicine, Estrogen receptor alpha, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Linda B. Moore, John T. Moore, Timothy M. Willson, Millard H. Lambert, Bruce Wisely, Steven A. Kliewer, D.D. McKee, Jodi M. Maglich
المصدر: Molecular Endocrinology. 16:977-986
مصطلحات موضوعية: Models, Molecular, Receptors, Steroid, Swine, Molecular Sequence Data, Receptors, Cytoplasmic and Nuclear, Xenopus Proteins, Retinoid X receptor, Biology, Transfection, Protein Structure, Secondary, Xenobiotics, Bile Acids and Salts, Evolution, Molecular, Mice, Xenopus laevis, Liver X receptor beta, Dogs, Endocrinology, Constitutive androstane receptor, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, Receptor, Molecular Biology, Constitutive Androstane Receptor, Phylogeny, Zebrafish, Pregnane X receptor, Binding Sites, Molecular Structure, Pregnane X Receptor, Liver X receptor alpha, Haplorhini, General Medicine, Rats, Biochemistry, Nuclear receptor, Steroids, Estrogen-related receptor gamma, Rabbits, Chickens, Sequence Alignment, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fff253434028bbfc7e82f5aab43e04
https://doi.org/10.1210/mend.16.5.0828 -
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المؤلفون: Donna J. Buckley, Srikanth C. Nallani, Rucha S. Sane, Bryan Goodwin, Arthur R. Buckley, Linda B. Moore, Pankaj B. Desai
المصدر: Drug Metabolism and Disposition. 30:608-612
مصطلحات موضوعية: Receptors, Steroid, medicine.medical_specialty, Metabolite, Receptors, Cytoplasmic and Nuclear, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Mixed Function Oxygenases, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Internal medicine, medicine, Cytochrome P-450 CYP3A, Humans, RNA, Messenger, skin and connective tissue diseases, Cells, Cultured, Pregnane X receptor, biology, CYP3A4, Pregnane X Receptor, Cytochrome P450, Antiestrogen, Tamoxifen, Endocrinology, Nuclear receptor, chemistry, Mechanism of action, Hepatocytes, biology.protein, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13557d4e44174333cc89b1449351d46
https://doi.org/10.1124/dmd.30.5.608 -
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المؤلفون: Timothy M. Willson, Michael A. Watson, Randy K. Bledsoe, Jonathon S. Russel, Thomas A. Spencer, Jon L. Collins, Dansu Li, John T. Moore, Derek J. Parks, Linda B. Moore, Thomas G. Consler, Cristin M. Galardi, Millard H. Lambert, David D. McKee
المصدر: Journal of Medicinal Chemistry. 44:886-897
مصطلحات موضوعية: Models, Molecular, Receptors, Steroid, Oxysterol, Blotting, Western, Molecular Sequence Data, Receptors, Cytoplasmic and Nuclear, Fluorescence, Cell Line, Structure-Activity Relationship, Nuclear Receptor Coactivator 1, Chlorocebus aethiops, Drug Discovery, Animals, Amino Acid Sequence, Liver X receptor, Receptor, Ketocholesterols, Transcription factor, Histone Acetyltransferases, Liver X Receptors, Cell Nucleus, Orphan receptor, Binding Sites, Cell-Free System, Chemistry, Tryptophan, Cholic Acids, Stereoisomerism, Orphan Nuclear Receptors, Hydroxycholesterols, DNA-Binding Proteins, Nuclear receptor coactivator 1, Sterols, Cholesterol, Energy Transfer, Nuclear receptor, Biochemistry, Molecular Medicine, lipids (amino acids, peptides, and proteins), Pharmacophore, Transcription Factors