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1دورية أكاديميةRab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth
المؤلفون: Linda Sawade, Federica Grandi, Marianna Mignanelli, Genaro Patiño-López, Kerstin Klinkert, Francina Langa-Vives, Roberta Di Guardo, Arnaud Echard, Alessandra Bolino, Volker Haucke
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth
المؤلفون: Kerstin Klinkert, Volker Haucke, Alessandra Bolino, Genaro Patino-Lopez, Linda Sawade, Francina Langa-Vives, Federica Grandi, Marianna Mignanelli, Roberta Di Guardo, Arnaud Echard
المساهمون: Leibniz Forschungsinstitut für Molekulare Pharmakolgie = Leibniz Institute for Molecular Pharmacology [Berlin, Allemagne] (FMP), Leibniz Association, IRCCS Ospedale San Raffaele [Milan, Italy], Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie] (UniSR), Hospital Infantil de México Federico Gómez (HIMFG), Trafic membranaire et Division cellulaire - Membrane Traffic and Cell Division, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur [Paris] (IP), Freie Universität Berlin, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Supported by grants from the German Research Foundation (DFG) (SFB958/A01 and HA2686/15-1 to V.H.), from Muscular Dystrophy Association (MDA574294) and AFM-Telethon France (#21528) to A.B., V.H. and A.B. are funded by E-Rare-3 JTC 2017 and are members of the eRARE Consortium 'Treat-MTMs'. Part of this work has been supported by Institut Pasteur and CNRS to A.E., K.K. was supported by the Pasteur - Paris University (PPU) International PhD Program and by and a fellowship from FRM (FDT20150532389)., Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.2835. ⟨10.1038/s41467-020-16696-6⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2835. ⟨10.1038/s41467-020-16696-6⟩مصطلحات موضوعية: 0301 basic medicine, Myelin biology and repair, General Physics and Astronomy, GTPase, mTORC1, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Small GTPases, chemistry.chemical_compound, Myelin, 0302 clinical medicine, Charcot-Marie-Tooth Disease, Gene Knock-In Techniques, Lipid signalling, lcsh:Science, Myelin Sheath, Multidisciplinary, Hyperactivation, Chemistry, Protein Tyrosine Phosphatases, Non-Receptor, Phenotype, 3. Good health, Cell biology, medicine.anatomical_structure, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Science, Primary Cell Culture, Down-Regulation, Mice, Transgenic, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, medicine, Animals, Humans, Phosphatidylinositol, Gene, General Chemistry, Nutrient signalling, Lipid Metabolism, nervous system diseases, 030104 developmental biology, HEK293 Cells, rab GTP-Binding Proteins, Astrocytes, Mutation, lcsh:Q, 030217 neurology & neurosurgery, Biogenesis, HeLa Cells
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المؤلفون: Gaëtan Chicanne, Francesca Bianchi, Linda Sawade, Ivan de Curtis, Ubaldo Del Carro, Yesim Parman, Marta Guerrero-Valero, Roberta Di Guardo, Davide Pareyson, Valeria Alberizzi, Bernard Payrastre, Federica Grandi, Silvia Cipriani, Angelo Schenone, Alessandra Bolino, Volker Haucke
المساهمون: Guerrero-Valero, M., Grandi, F., Cipriani, S., Alberizzi, V., Di Guardo, R., Chicanne, G., Sawade, L., Bianchi, F., Del Carro, U., De Curtis, I., Pareyson, D., Parman, Y., Schenone, A., Haucke, V., Payrastre, B., Bolino, A.
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Charcot-Marie-Tooth neuropathies, Schwann cells, myelin, myotubularin, phosphoinositides, Animals, Charcot-Marie-Tooth Disease, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Knockout, Myelin Sheath, Myosin Type II, Phosphatidylinositol Phosphates, Protein Tyrosine Phosphatases, Non-Receptor, rhoA GTP-Binding Protein, Signal Transduction, RHOA, Myotubularin, Knockout, mTORC1, Myelin, Myosin, medicine, Non-Receptor, Cytoskeleton, Multidisciplinary, biology, Chemistry, Myelin outfoldings, Biological Sciences, Cell biology, medicine.anatomical_structure, biology.protein, Signal transduction, Protein Tyrosine Phosphatases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdec724fd3719cb7bff8dddbaf9c0f2
http://hdl.handle.net/11567/1057661 -
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المؤلفون: Thomas Volkmer, Thomas Korte, Ali Saitov, Linda Sawade, Gabriele Beyer, Wolfgang Lockau, Iris Maldener, Dennis J. Nürnberg, Friederike Klemke
المصدر: Microbiology
مصطلحات موضوعية: GTP', Cations, Divalent, Gene Expression, Mannose, medicine.disease_cause, Microbiology, Divalent, chemistry.chemical_compound, Polyphosphates, Glucokinase, Escherichia coli, medicine, Cloning, Molecular, chemistry.chemical_classification, Microbial Viability, biology, Gene Expression Profiling, Polyphosphate, Temperature, Hydrogen-Ion Concentration, Anabaena, Molecular biology, Standard, Recombinant Proteins, Enzyme assay, Kinetics, Glucose, Biochemistry, chemistry, biology.protein, bacteria, Physiology and Biochemistry, Nucleoside, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ff53425ffb19aa3e001c72209e102e
https://doi.org/10.1099/mic.0.081836-0 -
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المؤلفون: Dmytro Puchkov, Gala A. Classen, Tanja Maritzen, Volker Haucke, Christian Rosenmund, Dorothea Lorenz, Natalia L. Kononenko, Arndt Pechstein, Linda Sawade, Thorsten Trimbuch, Natalie Kaempf, Alexander M. Walter
المصدر: Neuron. 82(5):981-988
مصطلحات موضوعية: Dynamins, Endosome, Neuroscience(all), Adaptor Protein Complex 2, Mice, Transgenic, Endosomes, Endocytosis, Clathrin, Synaptic vesicle, Hippocampus, Exocytosis, Bulk endocytosis, Mice, Animals, Dynamin, Neurons, biology, General Neuroscience, Coated Pits, Cell-Membrane, Models, Theoretical, Cell biology, Rats, Mice, Inbred C57BL, Synapses, biology.protein, Clathrin adaptor proteins, Synaptic Vesicles