المؤلفون: Tikvah K. Hayes, Elisa Aquilanti, Nicole S. Persky, Xiaoping Yang, Erica E. Kim, Lisa Brenan, Amy B. Goodale, Douglas Alan, Ted Sharpe, Robert E. Shue, Lindsay Westlake, Lior Golomb, Brianna R. Silverman, Myshal D. Morris, Ty Running Fisher, Eden Beyene, Yvonne Y. Li, Andrew D. Cherniack, Federica Piccioni, J. Kevin Hicks, Andrew S. Chi, Daniel P. Cahill, Jorg Dietrich, Tracy T. Batchelor, David E. Root, Cory M. Johannessen, Matthew Meyerson

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/0edde2f4b771457398e829246efe16d1

المؤلفون: Tikvah K. Hayes, Elisa Aquilanti, Nicole S. Persky, Xiaoping Yang, Erica E. Kim, Lisa Brenan, Amy B. Goodale, Douglas Alan, Ted Sharpe, Robert E. Shue, Lindsay Westlake, Lior Golomb, Brianna R. Silverman, Myshal D. Morris, Ty Running Fisher, Eden Beyene, Yvonne Y. Li, Andrew D. Cherniack, Federica Piccioni, J. Kevin Hicks, Andrew S. Chi, Daniel P. Cahill, Jorg Dietrich, Tracy T. Batchelor, David E. Root, Cory M. Johannessen, Matthew Meyerson

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c60cde2e831e452ca04b334e2136cd27

المؤلفون: Colin W. Garvie, Xiaoyun Wu, Malvina Papanastasiou, Sooncheol Lee, James Fuller, Gavin R. Schnitzler, Steven W. Horner, Andrew Baker, Terry Zhang, James P. Mullahoo, Lindsay Westlake, Stephanie H. Hoyt, Marcus Toetzl, Matthew J. Ranaghan, Luc de Waal, Joseph McGaunn, Bethany Kaplan, Federica Piccioni, Xiaoping Yang, Martin Lange, Adrian Tersteegen, Donald Raymond, Timothy A. Lewis, Steven A. Carr, Andrew D. Cherniack, Christopher T. Lemke, Matthew Meyerson, Heidi Greulich

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8c9d393dbd6b4b13a8ba16d21da8b36d

المؤلفون: Haiquan Chen, Jian Carrot-Zhang, Yue Zhao, Haichuan Hu, Samuel S. Freeman, Su Yu, Gavin Ha, Alison M. Taylor, Ashton C. Berger, Lindsay Westlake, Yuanting Zheng, Jiyang Zhang, Aruna Ramachandran, Qiang Zheng, Yunjian Pan, Difan Zheng, Shanbo Zheng, Chao Cheng, Muyu Kuang, Xiaoyan Zhou, Yang Zhang, Hang Li, Ting Ye, Yuan Ma, Zhendong Gao, Xiaoting Tao, Han Han, Jun Shang, Ying Yu, Ding Bao, Yechao Huang, Xiangnan Li, Yawei Zhang, Jiaqing Xiang, Yihua Sun, Yuan Li, Andrew D. Cherniack, Joshua D. Campbell, Leming Shi, Matthew Meyerson

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-6 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/4a9c53d05b3d4f2bb8b67fc34b59ad6c

المؤلفون: Douglas L, Orsi, Elisabeth, Pook, Nico, Bräuer, Anders, Friberg, Philip, Lienau, Christopher T, Lemke, Timo, Stellfeld, Ulf, Brüggemeier, Vera, Pütter, Hanna, Meyer, Maria, Baco, Stephanie, Tang, Andrew D, Cherniack, Lindsay, Westlake, Samantha A, Bender, Mustafa, Kocak, Craig A, Strathdee, Matthew, Meyerson, Knut, Eis, Jonathan T, Goldstein

المصدر: Journal of medicinal chemistry. 65(21)

مصطلحات موضوعية: PPAR gamma, Ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ae813451ab4026cd308dc1142c4ed2b6
https://pubmed.ncbi.nlm.nih.gov/36542814

المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein

المصدر: Journal of Medicinal Chemistry. 65:14843-14863

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bcec82278b2a513b7653d5a4ef4822cb
https://doi.org/10.1021/acs.jmedchem.2c01379

المؤلفون: Xiaoyun Wu, Gavin R. Schnitzler, Galen F. Gao, Brett Diamond, Andrew R. Baker, Bethany Kaplan, Kaylyn Williamson, Lindsay Westlake, Selena Lorrey, Timothy A. Lewis, Colin W. Garvie, Martin Lange, Sikander Hayat, Henrik Seidel, John Doench, Andrew D. Cherniack, Charlotte Kopitz, Matthew Meyerson, Heidi Greulich

المصدر: Journal of Biological Chemistry. 295:16464-16467

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::72fa51298ce54931ed8d31071052afbf
https://doi.org/10.1074/jbc.aac120.016548

المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein

المصدر: Journal of Medicinal Chemistry. 66:1082-1082

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ec4cea163f1d6c31ece521e358ffd5a2
https://doi.org/10.1021/acs.jmedchem.2c02002

المؤلفون: Yang Zhang, Samuel S. Freeman, Haichuan Hu, Ashton C. Berger, Yuan Li, Lindsay Westlake, Difan Zheng, Ying Yu, Joshua D. Campbell, Gavin Ha, Alison M. Taylor, Aruna Ramachandran, Leming Shi, Ding Bao, Qiang Zheng, Yechao Huang, Jian Carrot-Zhang, Ting Ye, Chao Cheng, Yunjian Pan, Yuanting Zheng, Jiyang Zhang, Xiaoyan Zhou, Shanbo Zheng, Yue Zhao, Yawei Zhang, Su Yu, Jun Shang, Hang Li, Yihua Sun, Yuan Ma, Haiquan Chen, Han Han, Matthew Meyerson, Xiaoting Tao, Xiangnan Li, Andrew D. Cherniack, Muyu Kuang, Jiaqing Xiang, Zhendong Gao

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-6 (2019)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, Receptor, ErbB-2, MAP Kinase Kinase 1, Loss of Heterozygosity, General Physics and Astronomy, medicine.disease_cause, Loss of heterozygosity, 0302 clinical medicine, HLA Antigens, lcsh:Science, Exome, Exome sequencing, Cancer, Aged, 80 and over, Multidisciplinary, RNA-Binding Proteins, Middle Aged, Proto-Oncogene Proteins c-met, 3. Good health, ErbB Receptors, 030220 oncology & carcinogenesis, Adenocarcinoma, Female, KRAS, Adult, Proto-Oncogene Proteins B-raf, DNA Copy Number Variations, Science, Receptors, Antigen, T-Cell, Receptors, Antigen, B-Cell, Adenocarcinoma of Lung, Adenocarcinoma in Situ, Human leukocyte antigen, Biology, Malignancy, Article, General Biochemistry, Genetics and Molecular Biology, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Exome Sequencing, Genetics, medicine, Humans, Neoplasm Invasiveness, neoplasms, Aged, Gene Expression Profiling, General Chemistry, medicine.disease, digestive system diseases, Gene expression profiling, 030104 developmental biology, Mutation, Cancer research, lcsh:Q, Tumor Suppressor Protein p53

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e869032752dccbe620cc15973c500df4
http://link.springer.com/article/10.1038/s41467-019-13460-3

المؤلفون: Adrian Tersteegen, Stephanie H. Hoyt, Steven A. Carr, Donald Raymond, Christopher T. Lemke, Federica Piccioni, James Mullahoo, Martin Lange, Xiaoping Yang, Bethany Kaplan, Colin W. Garvie, Andrew Baker, Marcus Toetzl, Heidi Greulich, Malvina Papanastasiou, Steven Horner, Luc de Waal, Timothy A. Lewis, James R. Fuller, Sooncheol Lee, Lindsay Westlake, Andrew D. Cherniack, Joseph McGaunn, Terry Zhang, Gavin R. Schnitzler, Matthew Meyerson, Matthew J. Ranaghan, Xiaoyun Wu

المصدر: 'Nature Communications ', vol: 12, pages: 4375-1-4375-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Cell death, 0301 basic medicine, Cancer therapy, Cell Survival, RNase P, Science, General Physics and Astronomy, Plasma protein binding, Mass Spectrometry, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Multienzyme Complexes, Cryoelectron microscopy, Catalytic Domain, Tetrahydroisoquinolines, Endoribonucleases, Humans, X-ray crystallography, Multidisciplinary, Calorimetry, Differential Scanning, Chemistry, HEK 293 cells, Intracellular Signaling Peptides and Proteins, Phosphodiesterase, General Chemistry, Heterotetramer, Adenosine Monophosphate, Cyclic Nucleotide Phosphodiesterases, Type 3, Recombinant Proteins, Cell biology, Pyridazines, Kinetics, HEK293 Cells, 030104 developmental biology, Structural biology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, Protein Multimerization, HeLa Cells, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfd121cbb4144ac667f5c20f822fddc
https://doi.org/10.1038/s41467-021-24495-w