المؤلفون: Cummings CT; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Linger RM; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Parker, CO, USA., Cohen RA; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Sather S; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Kirkpatrick GD; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Davies KD; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., DeRyckere D; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Earp HS; Department of Medicine, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA. Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Graham DK; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

المصدر: Oncotarget [Oncotarget] 2014 Nov 15; Vol. 5 (21), pp. 10434-45.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*pharmacology , Carcinoma, Non-Small-Cell Lung/*therapy , Lung Neoplasms/*therapy , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins/*metabolism , Receptor Protein-Tyrosine Kinases/*metabolism, Apoptosis/drug effects ; Apoptosis/genetics ; Carboplatin/pharmacology ; Carcinoma, Non-Small-Cell Lung/immunology ; Cell Line, Tumor ; Down-Regulation ; Drug Resistance/drug effects ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Lung Neoplasms/immunology ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Molecular Targeted Therapy ; Oncogene Protein v-akt/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/immunology ; RNA, Small Interfering/genetics ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/immunology ; STAT6 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Tumor Stem Cell Assay ; c-Mer Tyrosine Kinase

المؤلفون: Linger RM; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Lee-Sherick AB, DeRyckere D, Cohen RA, Jacobsen KM, McGranahan A, Brandão LN, Winges A, Sawczyn KK, Liang X, Keating AK, Tan AC, Earp HS, Graham DK

المصدر: Blood [Blood] 2013 Aug 29; Vol. 122 (9), pp. 1599-609. Date of Electronic Publication: 2013 Jul 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Targeted Therapy*, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Proto-Oncogene Proteins/*antagonists & inhibitors , Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors, Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Gene Expression Regulation, Leukemic/drug effects ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; RNA, Small Interfering/pharmacology ; RNA, Small Interfering/therapeutic use ; Xenograft Model Antitumor Assays ; c-Mer Tyrosine Kinase

المؤلفون: Linger RM; Department of Pediatrics, Section of Hematology, Oncology and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Cohen RA, Cummings CT, Sather S, Migdall-Wilson J, Middleton DH, Lu X, Barón AE, Franklin WA, Merrick DT, Jedlicka P, DeRyckere D, Heasley LE, Graham DK

المصدر: Oncogene [Oncogene] 2013 Jul 18; Vol. 32 (29), pp. 3420-31. Date of Electronic Publication: 2012 Aug 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation*, Carcinoma, Non-Small-Cell Lung/*metabolism , Lung Neoplasms/*metabolism , Proto-Oncogene Proteins/*metabolism , Receptor Protein-Tyrosine Kinases/*metabolism, Animals ; Apoptosis/physiology ; Blotting, Western ; Carcinoma, Non-Small-Cell Lung/pathology ; Drug Resistance, Neoplasm/physiology ; Female ; Gene Knockdown Techniques ; Humans ; Immunoprecipitation ; Lung Neoplasms/pathology ; Male ; Mice ; Middle Aged ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/physiology ; Tissue Array Analysis ; Xenograft Model Antitumor Assays ; c-Mer Tyrosine Kinase ; Axl Receptor Tyrosine Kinase

المؤلفون: Migdall-Wilson J; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Bates C, Schlegel J, Brandão L, Linger RM, DeRyckere D, Graham DK

المصدر: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31635. Date of Electronic Publication: 2012 Feb 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Cell Nucleus/*drug effects , Cell Nucleus/*enzymology , Intercellular Signaling Peptides and Proteins/*pharmacology , Leukemia/*enzymology , Proto-Oncogene Proteins/*metabolism , Receptor Protein-Tyrosine Kinases/*metabolism, Amino Acid Sequence ; Cell Compartmentation/drug effects ; Cell Line, Tumor ; Cell Membrane/enzymology ; Conserved Sequence ; Glycosylation/drug effects ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Ligands ; Molecular Sequence Data ; Molecular Weight ; Nuclear Export Signals ; Nuclear Localization Signals/chemistry ; Protein Biosynthesis/drug effects ; Protein Isoforms/chemistry ; Protein Isoforms/metabolism ; Proto-Oncogene Proteins/chemistry ; Receptor Protein-Tyrosine Kinases/chemistry ; Signal Transduction/drug effects ; Time Factors ; c-Mer Tyrosine Kinase

المؤلفون: Lee-Sherick AB; Department of Paediatrics, Section of Haematology, Oncology, and Bone Marrow Transplantation, University of Colorado Denver School of Medicine, Aurora, CO, USA., Linger RM, Gore L, Keating AK, Graham DK

المصدر: British journal of haematology [Br J Haematol] 2010 Nov; Vol. 151 (4), pp. 295-311. Date of Electronic Publication: 2010 Aug 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Molecular Targeted Therapy/*methods , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy, Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Child ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Epigenesis, Genetic/drug effects ; Humans ; Phosphotransferases/antagonists & inhibitors ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology

المؤلفون: Linger RM; University of Colorado Denver School of Medicine, Department of Pediatrics, Aurora, CO 80045, USA., Keating AK, Earp HS, Graham DK

المصدر: Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2010 Oct; Vol. 14 (10), pp. 1073-90.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101127833 Publication Model: Print Cited Medium: Internet ISSN: 1744-7631 (Electronic) Linking ISSN: 14728222 NLM ISO Abbreviation: Expert Opin Ther Targets Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms/*drug therapy , Proto-Oncogene Proteins/*antagonists & inhibitors , Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors, Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Clinical Trials as Topic ; Humans ; Neoplasms/genetics ; Oncogene Proteins/genetics ; Oncogene Proteins/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins/metabolism ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/metabolism ; Signal Transduction/drug effects ; Treatment Outcome ; Tumor Microenvironment ; Axl Receptor Tyrosine Kinase

المؤلفون: Linger RM; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA., DeRyckere D, Brandão L, Sawczyn KK, Jacobsen KM, Liang X, Keating AK, Graham DK

المصدر: Blood [Blood] 2009 Sep 24; Vol. 114 (13), pp. 2678-87. Date of Electronic Publication: 2009 Jul 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Retracted Publication

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*/methods, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Proto-Oncogene Proteins/*physiology , Receptor Protein-Tyrosine Kinases/*physiology, Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Survival/genetics ; Child ; Gene Expression Regulation, Leukemic ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Proto-Oncogene Proteins/antagonists & inhibitors ; Proto-Oncogene Proteins/genetics ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/pharmacology ; RNA, Small Interfering/therapeutic use ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors ; Receptor Protein-Tyrosine Kinases/genetics ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; c-Mer Tyrosine Kinase

المؤلفون: Goebel-Goody SM; University of Colorado Denver Anschutz Medical Campus, Aurora, CO 80045, USA., Davies KD, Alvestad Linger RM, Freund RK, Browning MD

المصدر: Neuroscience [Neuroscience] 2009 Feb 18; Vol. 158 (4), pp. 1446-59. Date of Electronic Publication: 2008 Nov 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0306-4522 (Print) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

مواضيع طبية MeSH: Hippocampus/*cytology , Neuronal Plasticity/*physiology , Receptors, N-Methyl-D-Aspartate/*metabolism , Synapses/*physiology, Animals ; Bicuculline/pharmacology ; Biophysical Phenomena ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; GABA Antagonists/pharmacology ; Glutamic Acid/metabolism ; Immunoprecipitation/methods ; In Vitro Techniques ; Male ; Neurons/drug effects ; Neurons/metabolism ; Organometallic Compounds/pharmacology ; Patch-Clamp Techniques ; Phenanthrolines/pharmacology ; Phosphorylation/drug effects ; Protein Subunits/metabolism ; Protein Transport ; Protein Tyrosine Phosphatases/antagonists & inhibitors ; Quinoxalines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Subcellular Fractions/metabolism ; Subcellular Fractions/ultrastructure ; Synapses/ultrastructure ; Tyrosine/metabolism

المؤلفون: Linger RM; Department of Pediatrics, University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA., Keating AK, Earp HS, Graham DK

المصدر: Advances in cancer research [Adv Cancer Res] 2008; Vol. 100, pp. 35-83.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370416 Publication Model: Print Cited Medium: Print ISSN: 0065-230X (Print) Linking ISSN: 0065230X NLM ISO Abbreviation: Adv Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms/*etiology , Neoplasms/*therapy , Oncogene Proteins/*physiology , Proto-Oncogene Proteins/*physiology , Receptor Protein-Tyrosine Kinases/*physiology, Animals ; Cell Survival ; Drug Delivery Systems ; Humans ; Models, Biological ; Neoplasm Invasiveness/genetics ; Neoplasms/genetics ; Neoplasms/pathology ; Neovascularization, Pathologic/genetics ; Oncogene Proteins/antagonists & inhibitors ; Oncogene Proteins/genetics ; Oncogene Proteins/metabolism ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins/antagonists & inhibitors ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/metabolism ; Signal Transduction/physiology ; Tumor Burden/genetics ; c-Mer Tyrosine Kinase ; Axl Receptor Tyrosine Kinase