يعرض 1 - 10 نتائج من 40 نتيجة بحث عن '"Lionel Guittat"', وقت الاستعلام: 0.90s تنقيح النتائج
  1. 1
    دورية أكاديمية
    The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells.

    المؤلفون: Nassima Temime-Smaali, Lionel Guittat, Assitan Sidibe, Kazuo Shin-ya, Chantal Trentesaux, Jean-François Riou

    المصدر: PLoS ONE, Vol 4, Iss 9, p e6919 (2009)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: http://europepmc.org/articles/PMC2732903?pdf=render; https://doaj.org/toc/1932-6203

    URL الوصول: https://doaj.org/article/de7d9fcca91541e09de07e06680f424f

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  2. 2
    G-quadruplex ligands as potent regulators of lysosomes

    المؤلفون: Lucille Ferret, Karla Alvarez-Valadez, Jennifer Rivière, Alexandra Muller, Natalia Bohálová, Luo Yu, Lionel Guittat, Vaclav Brázda, Guido Kroemer, Jean-Louis Mergny, Mojgan Djavaheri-Mergny

    المصدر: Autophagy. :1-15

    مصطلحات موضوعية: Cell Biology, Molecular Biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9b5a62efcb01e9677305699bf880fdd0
    https://doi.org/10.1080/15548627.2023.2170071

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  3. 3
    Supplementary Figures 1-9 from Telomere Targeting with a New G4 Ligand Enhances Radiation-Induced Killing of Human Glioblastoma Cells

    المؤلفون: Andreï Tchirkov, Pierre Verrelle, Jean-Louis Mergny, Phong Lan Thao Tran, Lionel Guittat, Anne De Cian, Emmanuel Chautard, Marie-Paule Teulade-Fichou, Jean-Marie Lehn, Anne Petitjean, Bertrand Evrard, Patrick Merle

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2f063260d3a8d034598a8e25299e5c
    https://doi.org/10.1158/1535-7163.22496886.v1

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  4. 4
    Supplementary Methods from Telomere Targeting with a New G4 Ligand Enhances Radiation-Induced Killing of Human Glioblastoma Cells

    المؤلفون: Andreï Tchirkov, Pierre Verrelle, Jean-Louis Mergny, Phong Lan Thao Tran, Lionel Guittat, Anne De Cian, Emmanuel Chautard, Marie-Paule Teulade-Fichou, Jean-Marie Lehn, Anne Petitjean, Bertrand Evrard, Patrick Merle

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b7e15bcdad8eeee1c813a6a00736bf
    https://doi.org/10.1158/1535-7163.22496883.v1

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  5. 5
    Data from Telomere Targeting with a New G4 Ligand Enhances Radiation-Induced Killing of Human Glioblastoma Cells

    المؤلفون: Andreï Tchirkov, Pierre Verrelle, Jean-Louis Mergny, Phong Lan Thao Tran, Lionel Guittat, Anne De Cian, Emmanuel Chautard, Marie-Paule Teulade-Fichou, Jean-Marie Lehn, Anne Petitjean, Bertrand Evrard, Patrick Merle

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::893d5c5098816cb838f7a5a6f683ce3e
    https://doi.org/10.1158/1535-7163.c.6535419

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  6. 6
    Télomères et télomérase : des cibles toujours pertinentes en oncologie ?

    المؤلفون: Lionel Guittat, Evelyne Ségal-Bendirdjian, Jean-Louis Mergny

    المساهمون: Laboratoire d'Optique et Biosciences (LOB), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École polytechnique (X), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)

    المصدر: Bulletin du Cancer
    Bulletin du Cancer, John Libbey Eurotext, 2020, ⟨10.1016/j.bulcan.2020.10.007⟩

    مصطلحات موضوعية: Cancer Research, Telomerase, [SDV.CAN]Life Sciences [q-bio]/Cancer, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Biology, G-quadruplex, 03 medical and health sciences, Imetelstat, 0302 clinical medicine, imételstat, Radiology, Nuclear Medicine and imaging, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, prolifération cellulaire, inhibiteur, 0303 health sciences, Hematology, General Medicine, Télomères, Telomere, Oncology, 030220 oncology & carcinogenesis, Cancer research, télomérase, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811cc3f8a6356e6c3a266e567de19814
    https://doi.org/10.1016/j.bulcan.2020.10.007

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  7. 7
    G-quadruplexes in helminth parasites

    المؤلفون: Alessio Cantara, Yu Luo, Michaela Dobrovolná, Natalia Bohalova, Miroslav Fojta, Daniela Verga, Lionel Guittat, Anne Cucchiarini, Solène Savrimoutou, Cécile Häberli, Jean Guillon, Jennifer Keiser, Václav Brázda, Jean Louis Mergny

    المساهمون: Mergny, Jean-Louis, Masaryk University [Brno] (MUNI), Institute of Biophysics of the Czech Academy of Sciences (IBP / CAS), Czech Academy of Sciences [Prague] (CAS), Laboratoire d'Optique et Biosciences (LOB), École polytechnique (X)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Chimie, Modélisation et Imagerie pour la Biologie [Orsay], Université Paris-Sud - Paris 11 (UP11)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Brno University of Technology [Brno] (BUT), Centre de recherche de l'Institut Curie [Paris], Institut Curie [Paris], Université Sorbonne Paris Nord, Acides Nucléiques : Régulations Naturelle et Artificielle (ARNA), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Basel (Unibas)

    المصدر: Nucleic Acids Research
    Nucleic Acids Research, In press, 50 (5), pp.2719-2735. ⟨10.1093/nar/gkac129⟩

    مصطلحات موضوعية: [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Genome, Nematoda, Ligands, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], G-Quadruplexes, Platyhelminths, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Helminths, parasitic diseases, Genetics, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Animals, Humans, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Cattle, Parasites, [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedc70ab9dabadf6eaab596fe4fccce5
    https://edoc.unibas.ch/90405/

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  8. 8
    Regulatory interplay between Vav1, Syk and β-catenin occurs in lung cancer cells

    المؤلفون: Vanessa Laurienté, Antonin Oudar, Christine Le Roy, Lionel Guittat, Souleymane Harouna-Rachidi, Laura Gardano, Rofia Boudria, Nadine Varin-Blank, Elisabetta Dondi

    المصدر: Cellular signalling. 86

    مصطلحات موضوعية: VAV1, Lung Neoplasms, Cytoskeleton organization, Chemistry, Syk, Signal transducing adaptor protein, RAC1, Cell Biology, Cell biology, Humans, Syk Kinase, Ectopic expression, Guanine nucleotide exchange factor, Signal transduction, Phosphorylation, Proto-Oncogene Proteins c-vav, beta Catenin, Adaptor Proteins, Signal Transducing, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ca77eeb17d5bf51084fa0acc4dfcb7
    https://pubmed.ncbi.nlm.nih.gov/34252536

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  9. 9
    [Are telomeres and telomerase still relevant targets in oncology?]

    المؤلفون: Jean-Louis, Mergny, Lionel, Guittat, Évelyne, Ségal-Bendirdjian

    المصدر: Bulletin du cancer. 108(1)

    مصطلحات موضوعية: Oncolytic Virotherapy, Oncolytic Viruses, Neoplasms, Nucleic Acids, Humans, RNA, Immunotherapy, Enzyme Inhibitors, Telomere, Telomerase

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f083265f0948cd257965448ccd33d207
    https://pubmed.ncbi.nlm.nih.gov/33256968

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  10. 10
    Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia

    المؤلفون: Maude Quettier, Dominique Ledoux, Christine Le Roy, Marouane Bouyaba, Stéphanie Le Coquil, Vincent Levy, Lionel Guittat, Nadine Varin-Blank, Stéphane Saint-Georges, Florence Ajchenbaum-Cymbalista, Vanessa Laurienté

    المساهمون: Adaptateurs de signalisation en hématologie (ASIH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Sorbonne Paris Cité (USPC)-Université Paris 13 (UP13), Université Paris 13 (UP13), Centre d'Investigations Cliniques 9504, Université Paris Diderot - Paris 7 (UPD7)-Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

    المصدر: Oncotarget
    Oncotarget, Impact journals, 2016, 7 (27), ⟨10.18632/oncotarget.9031⟩

    مصطلحات موضوعية: 0301 basic medicine, Receptors, CXCR4, CXCR4/CXCR5, [SDV]Life Sciences [q-bio], Chronic lymphocytic leukemia, B-cell receptor, Down-Regulation, Lymphadenopathy, CXCR5, 03 medical and health sciences, hemic and lymphatic diseases, Tumor Cells, Cultured, medicine, Humans, Phosphorylation, Lymph node, Protein Kinase C, Protein kinase C, B-Lymphocytes, Gene Expression Regulation, Leukemic, business.industry, breakpoint cluster region, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, Oncology, Proto-Oncogene Proteins c-bcr, Immunology, Cancer research, Lymph, IGHV@, business, CLL, protein kinase D, Research Paper, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbf616009d19fb98ab47a8ebbfa2162
    https://doi.org/10.18632/oncotarget.9031

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