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1
المؤلفون: John Moliterni, Arco Y. Jeng, John Fitt, Lisa B. Stamford, Eli M. Wallace, L. Blanchard, Mary Chou, S. De Lombaert, Jenny Tan, Paula Savage, Daniel Hoyer, N. Marcopoulos, D. Simonsbergen, Angelo J. Trapani, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 43:488-504
مصطلحات موضوعية: Male, medicine.hormone, Endothelin converting enzyme 1, Stereochemistry, Organophosphonates, Tetrazoles, Blood Pressure, Endothelin-Converting Enzymes, Rats, Sprague-Dawley, Endothelins, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Structure–activity relationship, Tetrazole, Enzyme Inhibitors, Protein Precursors, education, Benzofurans, education.field_of_study, Endothelin-1, biology, Phosphoramidon, Metalloendopeptidases, Stereoisomerism, Endothelin 1, Combinatorial chemistry, Rats, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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2
المؤلفون: Mary Chou, Michael A. Moskal, Arco Y. Jeng, Nicholas Marcopulos, Eli M. Wallace, Alan D. Neubert, John Moliterni, Lisa B. Stamford, Angelo J. Trapani, Paula Savage
المصدر: Journal of Medicinal Chemistry. 41:1513-1523
مصطلحات موضوعية: Male, Stereochemistry, Endothelin converting enzyme 1, Molecular Sequence Data, Organophosphonates, Blood Pressure, Peptide, CHO Cells, Tripeptide, Endothelin-Converting Enzymes, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Amide, Drug Discovery, Peptide synthesis, Animals, Aspartic Acid Endopeptidases, Humans, Amino Acid Sequence, Enzyme Inhibitors, education, Peptide sequence, chemistry.chemical_classification, education.field_of_study, Dipeptide, Endothelin-1, Acetylene, Metalloendopeptidases, Phosphonate, Recombinant Proteins, Rats, chemistry, Drug Design, Molecular Medicine, Neprilysin
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3
المؤلفون: Michael A. Moskal, Dongchu Wei, Lisa B. Stamford, Jenny Tan, Clive Gideon Diefenbacher, Eli M. Wallace, L. Blanchard, Paula Savage, Stéphane De Lombaert, Hoyer Denton W, Arco Y. Jeng
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:1059-1064
مصطلحات موضوعية: chemistry.chemical_classification, education.field_of_study, biology, Endothelin converting enzyme 1, Stereochemistry, fungi, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, law.invention, Enzyme, chemistry, law, Enzyme inhibitor, Drug Discovery, Recombinant DNA, biology.protein, Molecular Medicine, Moiety, education, Endothelin receptor, Molecular Biology, Neprilysin, IC50
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4
المؤلفون: Lisa B. Stamford, L. Blanchard, Angelo J. Trapani, Yumi Sakane, R. D. Ghai, Stéphane De Lombaert, Carol Berry
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:2875-2880
مصطلحات موضوعية: chemistry.chemical_classification, Metalloproteinase, biology, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Angiotensin-converting enzyme, Biochemistry, In vitro, Enzyme, Atrial natriuretic peptide, chemistry, Drug Discovery, Renin–angiotensin system, biology.protein, Molecular Medicine, Molecular Biology, Neprilysin, Tricyclic
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5
المؤلفون: Donald Mark Sperbeck, L. Blanchard, Herman R. Rodriguez, Michael Grim, Stéphane De Lombaert, Lisa B. Stamford, Todd M. Jenson
المصدر: Tetrahedron Letters. 35:7513-7516
مصطلحات موضوعية: chemistry.chemical_classification, Dipeptide, biology, Stereochemistry, Organic Chemistry, Angiotensin-converting enzyme, Biochemistry, chemistry.chemical_compound, Orally active, Enzyme, medicine.anatomical_structure, chemistry, Intramolecular force, Drug Discovery, Indoline, biology.protein, medicine, Nucleus, Tricyclic