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المؤلفون: Steven P. Seitz, John T. Hunt, Kelly L. Covello, Lisa Elkin, Gregory D. Vite, Yuval Blat, Jay A. Markwalder, Jonathan G. Pabalan, Maria Jure-Kunkel
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:582-585
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Carboxylic Acids, Pharmaceutical Science, Biochemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Drug Discovery, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Urea, Enzyme Inhibitors, Indoleamine 2,3-dioxygenase, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Tryptophan, Metabolic stability, High-Throughput Screening Assays, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Microsomes, Liver, Molecular Medicine, Intracellular, Kynurenine, HeLa Cells
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المؤلفون: Wilson Z. Shou, Lisa Elkin, Lizbeth Gallagher, Kathy Mosure, Matthew G. Soars, Andrew Dennis Wagner, Lindsey K. Stavola
المصدر: Rapid Communications in Mass Spectrometry. 30:1787-1796
مصطلحات موضوعية: Reproducibility, Chromatography, Chemistry, Drug discovery, Electrospray ionization, 010401 analytical chemistry, Organic Chemistry, Selected reaction monitoring, Mass spectrometry, Tandem mass spectrometry, 030226 pharmacology & pharmacy, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Matrix (chemical analysis), 03 medical and health sciences, 0302 clinical medicine, medicine, Pitavastatin, Spectroscopy, medicine.drug
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المؤلفون: Debra, Nickischer, Lisa, Elkin, Normand, Cloutier, Jonathan, O'Connell, Martyn, Banks, Andrea, Weston
المصدر: Methods in molecular biology (Clifton, N.J.). 1683
مصطلحات موضوعية: Microscopy, Data Interpretation, Statistical, Drug Discovery, Image Processing, Computer-Assisted, Cluster Analysis, Humans, Reproducibility of Results, Hep G2 Cells, High-Throughput Screening Assays, Molecular Imaging
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d027fbc415718506ef93b476f0f615b4
https://pubmed.ncbi.nlm.nih.gov/29082493 -
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المؤلفون: Martyn Banks, Andrea D. Weston, Lisa Elkin, Jonathan O’Connell, Debra Nickischer, Normand J. Cloutier
المصدر: Methods in Molecular Biology ISBN: 9781493973552
مصطلحات موضوعية: 0301 basic medicine, education.field_of_study, Computer science, Drug discovery, Scale (chemistry), Phenotypic screening, Population, 01 natural sciences, Data science, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, 030104 developmental biology, High-content screening, education, Throughput (business)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2773afaf4e6bf70a4e60829b2e3d6bde
https://doi.org/10.1007/978-1-4939-7357-6_11 -
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المؤلفون: Stephen R. Johnson, Dianlin Xie, Lihong Cheng, Yang Hong, John S. Tokarski, Adriana Zupa-Fernandez, Jodi K. Muckelbauer, Mark R. Witmer, Sophie Wu, Chiehying Chang, Donna L. Pedicord, Suzanne C. Edavettal, David S. Weinstein, William J. Pitts, Yuval Blat, James R. Burke, Lisa Elkin, Kristen Pike, Jeffrey Tredup
المصدر: Journal of Biological Chemistry. 290:11061-11074
مصطلحات موضوعية: Models, Molecular, T-Lymphocytes, Allosteric regulation, Biology, Crystallography, X-Ray, Biochemistry, TYK2 Kinase, Enzyme Stability, Functional selectivity, Humans, Molecular Biology, Janus kinase 1, Janus kinase 3, Janus Kinase 3, Receptors, Interleukin-2, Janus Kinase 1, Cell Biology, Protein Structure, Tertiary, Cell biology, Tyrosine kinase 2, Signal transduction, Janus kinase, Receptors, Thrombopoietin, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9176c99caf70572ecd7615a142c06a
https://doi.org/10.1074/jbc.m114.619502 -
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المؤلفون: Lizbeth Gallagher, Jun Zhang, Wilson Z. Shou, Harold N. Weller, Lisa Elkin, Marianne Vath
المصدر: Journal of Chromatography B. 967:211-218
مصطلحات موضوعية: Organic Cation Transport Proteins, Clinical Biochemistry, Biochemistry, Analytical Chemistry, Cycle time, Tandem Mass Spectrometry, Lc ms ms, medicine, Humans, Throughput (business), Chromatography, Chemistry, Silicates, ORGANIC CATION TRANSPORTER 2, Reproducibility of Results, Transporter, Cell Biology, General Medicine, Metformin, High-Throughput Screening Assays, HEK293 Cells, Graphitic carbon, Multiple injection, Graphite, Chromatography, Liquid, medicine.drug
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المؤلفون: Mary Ellen Cvijic, A. David Rodrigues, Matthew G. Soars, Lisa Elkin, Tatyana Zvyaga, Yurong Lai
المصدر: Drug Metabolism and Disposition. 42:566-574
مصطلحات موضوعية: medicine.drug_class, Pharmaceutical Science, ATP-binding cassette transporter, Biology, Models, Biological, Bile Acids and Salts, Feces, Sulfation, Cholestasis, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 11, Pharmacology, Bile acid, Kinase, Bile Canaliculi, Biological Transport, Transporter, medicine.disease, Bile Salt Export Pump, Biochemistry, Hepatocytes, ATP-Binding Cassette Transporters, Chemical and Drug Induced Liver Injury, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77495db29a5c16f7d145e5d1a9193168
https://doi.org/10.1124/dmd.113.054205 -
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المؤلفون: Andrew D, Wagner, Lisa, Elkin, Kathy, Mosure, Lizbeth, Gallagher, Lindsey K, Stavola, Matthew G, Soars, Wilson, Shou
المصدر: Rapid communications in mass spectrometry : RCM. 30(15)
مصطلحات موضوعية: Liver-Specific Organic Anion Transporter 1, Tandem Mass Spectrometry, Drug Discovery, Solid Phase Extraction, Humans, Reproducibility of Results, Chromatography, Liquid
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المؤلفون: Joanne L. Sproston, Robert J. Riley, Lisa Elkin, Patrick Barton, Kathleen W. Mosure, Matthew G. Soars
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 44(7)
مصطلحات موضوعية: Drug, Male, Quantitative structure–activity relationship, Organic anion transporter 1, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Drug Evaluation, Preclinical, Quantitative Structure-Activity Relationship, Pharmacology, Organic Anion Transporters, Sodium-Independent, Toxicology, Kidney, Biochemistry, Inhibitory Concentration 50, Organic Anion Transport Protein 1, Pharmacokinetics, In vivo, Animals, Humans, media_common, biology, Transporter, General Medicine, In vitro, Rats, Renal Elimination, HEK293 Cells, Drug Design, biology.protein, Clearance
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المؤلفون: James W. Darrow, Aaron Bourret, Robert Desimone, Jin-Ming Xiong, Patricia Maciejewski, Seung H. Lee, David C. Eustice, Mihaela Diana Danca, Douglas A. Pippin, David R. Brittelli, Kropf Jeffrey E, Peter Blomgren, Melissa Hill-Drzewi, Kevin S. Currie, Lisa Elkin, Steven L. Gallion, Scott A. Mitchell
المصدر: Bioorganicmedicinal chemistry letters. 19(24)
مصطلحات موضوعية: animal structures, Angiogenesis, Clinical Biochemistry, Receptor, EphB4, Pharmaceutical Science, Angiogenesis Inhibitors, Biochemistry, Receptor tyrosine kinase, chemistry.chemical_compound, Growth factor receptor, Cell Line, Tumor, Drug Discovery, Humans, Urea, Receptor, Molecular Biology, Protein Kinase Inhibitors, biology, Phenylurea Compounds, Organic Chemistry, Imidazoles, Angiopoietin receptor, Vascular endothelial growth factor, chemistry, Pyrazines, embryonic structures, biology.protein, Cancer research, Molecular Medicine, Signal transduction, Platelet-derived growth factor receptor