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المؤلفون: Kurt Gordon Pike, Christopher J. Lynch, Robert te Poele, Stephen Green, Carl S. Rye, Emmanuel de Billy, Keith Jones, Julie Demeritt, Paul D. Kemmitt, Nicola E. A. Chessum, Kevin Michael Foote, Louise Goodwin, Paul Workman, Florence I. Raynaud, Alan T. Henley, Swee Y. Sharp, Angela Hayes, Rosie Isaac, Lisa O’ Fee, Joanna Boros, Lorenzo Zani, Julie A. Tucker, Matthew D. Cheeseman, Scott G. Lamont, Paul Faulder
المصدر: Medchemcomm
MedChemComm (Online) 7 (2016): 1580–1586. doi:10.1039/C6MD00159A
info:cnr-pdr/source/autori:Carl S. Rye, Nicola E. A. Chessum, Scott Lamont, Kurt G. Pike, Paul Faulder, Julie Demeritt,Paul Kemmitt, Julie Tucker, Lorenzo Zani, Matthew D. Cheeseman, Rosie Isaac, Louise Goodwin, Joanna Boros, Florence Raynaud, Angela Hayes, Alan T. Henley, Emmanuel de Billy, Christopher J. Lynch, Swee Y. Sharp, Robert te Poele, Lisa O' Fee, Kevin M. Foote, Stephen Green, Paul Workman, Keith Jones/titolo:Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9/doi:10.1039%2FC6MD00159A/rivista:MedChemComm (Online)/anno:2016/pagina_da:1580/pagina_a:1586/intervallo_pagine:1580–1586/volume:7مصطلحات موضوعية: 0301 basic medicine, Phenotypic screening, Pharmaceutical Science, Pharmacology, Biology, Biochemistry, 03 medical and health sciences, HSF1, kinase inhibitor, cancer, pyrimidine, phenotypic screening, Drug Discovery, medicine, Potency, Transcription factor, Cell survival, chemistry.chemical_classification, Organic Chemistry, fungi, Cancer, medicine.disease, Cell biology, Chemistry, 030104 developmental biology, Enzyme, chemistry, Molecular Medicine, Cyclin-dependent kinase 9
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6ce0847e97e3ad58a24d19ca03ebf9
https://pubmed.ncbi.nlm.nih.gov/27746890 -
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المؤلفون: Lisa O’ Fee, Julie A. Tucker, Julie Demeritt, Emmanuel de Billy, Matthew D. Cheeseman, Kevin Michael Foote, Stephen Green, Kurt Gordon Pike, Scott G. Lamont, Louise Goodwin, Paul D. Kemmitt, Christopher J. Lynch, Paul Workman, Lorenzo Zani, Swee Y. Sharp, Alan T. Henley, Nicola E. A. Chessum, Rosie Isaac, Paul Faulder, Keith Jones, Robert te Poele, Carl S. Rye, Angela Hayes, Florence I. Raynaud, Joanna Boros
المصدر: MedChemComm. 7:1870-1870
مصطلحات موضوعية: Pharmacology, Stress (mechanics), Biochemistry, Chemistry, Drug Discovery, Organic Chemistry, Pharmaceutical Science, Molecular Medicine, Cyclin-dependent kinase 9, HSF1, Combinatorial chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b6d5eaa36d49e84b057c0ca284c84b1e
https://doi.org/10.1039/c6md90040b