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المؤلفون: Jamie Rossjohn, Lars Fugger, Lise T. Jensen
المصدر: Fugger, L, Jensen, L T & Rossjohn, J 2020, ' Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases ', Cell, vol. 181, no. 1, pp. 63-80 . https://doi.org/10.1016/j.cell.2020.03.007
مصطلحات موضوعية: 0303 health sciences, medicine.medical_specialty, MEDLINE, Biology, General Biochemistry, Genetics and Molecular Biology, Autoimmune Diseases, 03 medical and health sciences, 0302 clinical medicine, Immune system, Intervention (counseling), medicine, Humans, Immunotherapy, Intensive care medicine, Immunosuppressive Agents, 030217 neurology & neurosurgery, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd8e723eb9669317d3b30b25522b5af
https://doi.org/10.1016/j.cell.2020.03.007 -
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المؤلفون: Paulius Viskaitis, Myrtha Arnold, Celia Garau, Lise T. Jensen, Lars Fugger, Daria Peleg-Raibstein, Denis Burdakov
المصدر: Viskaitis, P, Arnold, M, Garau, C, Jensen, L T, Fugger, L, Peleg-Raibstein, D & Burdakov, D 2022, ' Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice ', Current biology : CB, vol. 32, no. 8, pp. 1812-1821.e4 . https://doi.org/10.1016/j.cub.2022.02.067
مصطلحات موضوعية: Mammals, Neurons, Orexins, amino acids, food intake, behavior, digestive, oral, and skin physiology, Hypothalamus, Brain, exploration, General Biochemistry, Genetics and Molecular Biology, Eating, Mice, Glucose, appetite, orexin, Animals, Amino Acids, hypocretin, hypothalamus, diet, General Agricultural and Biological Sciences
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a60d63abe9ed32f0ad5049914bc253
https://doi.org/10.1016/j.cub.2022.02.067 -
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المؤلفون: Kathrine E. Attfield, Elizabeth J. Soilleux, Orit Rozenblatt-Rosen, Lise T. Jensen, Lars Fugger, Lan T. Nguyen, Matan Hofree, Aggelakopoulou M, Aviv Regev, Lee J, Anna Neumann, Thomas R Barber, Gil McVean, Davies Jl, Kaur G, Porter Cbm, Danielle Dionne, Subita Balaram Kuttikkatte, Orr Ashenberg, Mary Carrington, Hayley G. Evans, Samantha J. Riesenfeld, Desel Cae, Ayshwarya Subramanian, Inbal Avraham-Davidi
مصطلحات موضوعية: Fetus, Spiral artery, Angiogenesis, Trophoblast, Intrauterine growth restriction, Biology, medicine.disease, Andrology, medicine.anatomical_structure, KIR2DL1, embryonic structures, medicine, Genetic predisposition, Receptor, reproductive and urinary physiology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd74f84be5053402b6acedf26e47f594
https://doi.org/10.1101/2021.03.26.437292 -
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المؤلفون: Maria Evangelidou, Vivian Tseveleki, Ioannis Kanistras, Fotis Lampros, Hans Lassmann, Anastasia Dagkonaki, Maria-Eleni Androutsou, Irini Papazian, Theodore Tselios, Torben Ruhwedel, Lise T. Jensen, Maria Anagnostouli, Maria Avloniti, Lesley Probert, John Matsoukas, Wiebke Möbius
المصدر: Frontiers in Immunology
Dagkonaki, A, Avloniti, M, Evangelidou, M, Papazian, I, Kanistras, I, Tseveleki, V, Lampros, F, Tselios, T, Jensen, L T, Möbius, W, Ruhwedel, T, Androutsou, M E, Matsoukas, J, Anagnostouli, M, Lassmann, H & Probert, L 2020, ' Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions ', Frontiers in Immunology, vol. 11, 575451 . https://doi.org/10.3389/fimmu.2020.575451
Frontiers in Immunology, Vol 11 (2020)مصطلحات موضوعية: 0301 basic medicine, Male, Myeloid, T-Lymphocytes, multiple sclerosis, Lymphocyte Activation, Immune tolerance, Myelin, 0302 clinical medicine, immune system diseases, Immunology and Allergy, Medicine, M2 macrophages, antigen-specific immunotherapy, Myeloid Cells, Cells, Cultured, Original Research, biology, Greece, Experimental autoimmune encephalomyelitis, Middle Aged, medicine.anatomical_structure, Spinal Cord, neuroprotection, Female, Immunosuppressive Agents, lcsh:Immunologic diseases. Allergy, PD-L1, Adult, Encephalomyelitis, Autoimmune, Experimental, Synaptosomal-Associated Protein 25, CNS demyelination, T cell, Immunology, Mice, Transgenic, Neuroprotection, Myelin oligodendrocyte glycoprotein, MOGAD, 03 medical and health sciences, Young Adult, Ym1/Chi3l3, Animals, Humans, Cell Proliferation, business.industry, humanized DR2 mice, Interleukin-2 Receptor alpha Subunit, Myelin Basic Protein, HLA-DR Antigens, medicine.disease, Axons, nervous system diseases, Mice, Inbred C57BL, 030104 developmental biology, nervous system, Gene Expression Regulation, Case-Control Studies, biology.protein, Interleukin-2, business, lcsh:RC581-607, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb7385b0b831c52b951e62281ba380d
http://europepmc.org/articles/PMC7711156 -
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المؤلفون: Jørgen Frøkiær, Christiane Desel, Britta Brügger, Paul M. Matthews, Lise T. Jensen, Soren L. Faergeman, Calliope A. Dendrou, Annette Bang Oturai, Hayley G. Evans, Christian Lüchtenborg, Mette Sommerlund, Subita Balaram Kuttikkatte, Lars Fugger, Manuel A. Friese, Kathrine E. Attfield
المساهمون: Medical Research Council (MRC), Merck Serono Ltd
المصدر: Cell Death & Disease
Faergeman, S L, Evans, H, Attfield, K E, Desel, C, Kuttikkatte, S B, Sommerlund, M, Jensen, L T, Frokiaer, J, Friese, M A, Matthews, P M, Luchtenborg, C, Brügger, B, Oturai, A B, Dendrou, C A & Fugger, L 2020, ' A novel neurodegenerative spectrum disorder in patients with MLKL deficiency ', Cell Death and Disease, vol. 11, no. 5, 303 . https://doi.org/10.1038/s41419-020-2494-0
Faergeman, S L, Evans, H, Attfield, K E, Desel, C, Kuttikkatte, S B, Sommerlund, M, Jensen, L T, Frokiaer, J, Friese, M A, Matthews, P M, Luchtenborg, C, Brügger, B, Oturai, A B, Dendrou, C A & Fugger, L 2020, ' A novel neurodegenerative spectrum disorder in patients with MLKL deficiency ', Cell Death and Disease, vol. 11, 303 . https://doi.org/10.1038/s41419-020-2494-0
Cell Death and Disease, Vol 11, Iss 5, Pp 1-13 (2020)مصطلحات موضوعية: Nervous system, Cancer Research, Programmed cell death, Ataxia, Necroptosis, Immunology, Central nervous system, Apoptosis, 0601 Biochemistry and Cell Biology, Bioinformatics, Article, Frameshift mutation, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Atrophy, medicine, Animals, Humans, 1112 Oncology and Carcinogenesis, lcsh:QH573-671, Neurodegeneration, Phosphorylation, 030304 developmental biology, 0303 health sciences, lcsh:Cytology, business.industry, Neurodegenerative diseases, Cell Biology, medicine.disease, MAP Kinase Kinase Kinases, 3. Good health, medicine.anatomical_structure, Receptor-Interacting Protein Serine-Threonine Kinases, medicine.symptom, business, Protein Kinases, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Molly Strom, Lars Fugger, J. Antonio González, Lise T. Jensen, Panagiota Iordanidou, Denis Burdakov
المصدر: Europe PubMed Central
González, J A, Jensen, LT, Iordanidou, P, Strom, M, Fugger, L & Burdakov, D 2016, ' Inhibitory Interplay between Orexin Neurons and Eating ', Current Biology, vol. 26, no. 18, pp. 2486-2491 . https://doi.org/10.1016/j.cub.2016.07.013
González, J A, Jensen, L T, Iordanidou, P, Strom, M, Fugger, L & Burdakov, D 2016, ' Inhibitory Interplay between Orexin Neurons and Eating ', Current Biology, vol. 26, no. 18, pp. 2486-91 . https://doi.org/10.1016/j.cub.2016.07.013مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Cell, Net energy, Biology, Inhibitory postsynaptic potential, General Biochemistry, Genetics and Molecular Biology, Eating, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Journal Article, medicine, Animals, Obesity, Overeating, Neurons, 2. Zero hunger, Orexins, Agricultural and Biological Sciences(all), Cell control, Biochemistry, Genetics and Molecular Biology(all), Brain, Feeding Behavior, medicine.disease, Orexin, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, medicine.symptom, Energy Intake, Energy Metabolism, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Dieting
وصف الملف: application/pdf
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المؤلفون: Lars Fugger, Nick Willcox, Lise T. Jensen, Manuel A. Friese
مصطلحات موضوعية: Autoimmune disease, Transgene, Immunology, Hematopoietic Stem Cell Transplantation, Mice, Transgenic, Disease, Human leukocyte antigen, Biology, medicine.disease, Autoimmune Diseases, Pathogenesis, Disease Models, Animal, Mice, Immune system, Humanized mouse, medicine, Animals, Humans, Immunology and Allergy, Stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888871a9361e557eb41b43bdee21afee
https://ora.ox.ac.uk/objects/uuid:600d3834-04a0-4d4a-9e8e-92598c0877e3 -
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المؤلفون: Lise T. Jensen, Lars Fugger, J. Antonio González, Denis Burdakov
المصدر: European Journal of Neuroscience. 35:1426-1432
مصطلحات موضوعية: 0303 health sciences, medicine.medical_specialty, Lateral hypothalamus, General Neuroscience, Efferent, Neuropeptide, Biology, Orexin, Ventral tegmental area, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, medicine.anatomical_structure, nervous system, Hypothalamus, Internal medicine, medicine, Locus coeruleus, Zona incerta, Neuroscience, psychological phenomena and processes, 030217 neurology & neurosurgery, 030304 developmental biology
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المؤلفون: Lise T. Jensen, Denis Burdakov, Mahesh M. Karnani, Anne Venner, Lars Fugger
المصدر: The Journal of Physiology. 589:639-651
مصطلحات موضوعية: 0303 health sciences, medicine.medical_specialty, Physiology, Glutamate receptor, Strychnine, Biology, Inhibitory postsynaptic potential, gamma-Aminobutyric acid, Orexin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, chemistry, Postsynaptic potential, Internal medicine, medicine, Excitatory postsynaptic potential, Glycine receptor, Neuroscience, 030217 neurology & neurosurgery, 030304 developmental biology, medicine.drug
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المؤلفون: J. A. Gonzalez, Lars Fugger, Douglas A. Bayliss, Denis Burdakov, Lise T. Jensen, Susan E. Doyle, Manuel Miranda-Anaya, Michael Menaker
المصدر: González, J A, Jensen, L T, Doyle, S E, Miranda-Anaya, M, Menaker, M, Fugger, L, Bayliss, D A & Burdakov, D 2009, ' Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons ', European Journal of Neuroscience, vol. 30, no. 1, pp. 57-64 . https://doi.org/10.1111/j.1460-9568.2009.06789.x
European Journal of Neuroscienceمصطلحات موضوعية: Patch-Clamp Techniques, Potassium Channels, Transgene, Green Fluorescent Proteins, Action Potentials, Neuropeptide, Mice, Transgenic, Nerve Tissue Proteins, In Vitro Techniques, Motor Activity, Biology, Article, Membrane Potentials, Mice, 03 medical and health sciences, Potassium Channels, Tandem Pore Domain, 0302 clinical medicine, Animals, Patch clamp, 030304 developmental biology, Mice, Knockout, Neurons, Membrane potential, Orexins, 0303 health sciences, General Neuroscience, digestive, oral, and skin physiology, Neuropeptides, Intracellular Signaling Peptides and Proteins, Brain, Feeding Behavior, Hydrogen-Ion Concentration, Potassium channel, Orexin, Glucose, nervous system, Hypothalamus, Knockout mouse, Neuroscience, psychological phenomena and processes, 030217 neurology & neurosurgery