يعرض 1 - 10 نتائج من 28 نتيجة بحث عن '"Lj, Ransone"', وقت الاستعلام: 1.69s تنقيح النتائج
  1. 1
    Transformation by Jun: requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos

    المؤلفون: Im, Morgan, Lj, Ransone, Tj, Bos, Im, Verma, Peter K Vogt

    المصدر: Europe PubMed Central

    مصطلحات موضوعية: Chloramphenicol O-Acetyltransferase, Transcriptional Activation, Leucine Zippers, Transcription, Genetic, Protein Conformation, Proto-Oncogene Proteins c-jun, Blotting, Western, Molecular Sequence Data, Genes, fos, Chick Embryo, Transfection, DNA-Binding Proteins, Cell Transformation, Neoplastic, Genes, jun, Protein Biosynthesis, Mutagenesis, Site-Directed, Animals, Amino Acid Sequence, Chickens, Proto-Oncogene Proteins c-fos, Cells, Cultured

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::14d0e3fcb6a684747b104cf53e6db196
    https://pubmed.ncbi.nlm.nih.gov/1594243

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  2. 2
    دورية أكاديمية
    Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kappaB mediated gene expression.

    المؤلفون: Palanki MS; Celgene Signal Research Division, 5555 Oberlin Drive, San Diego, CA 92121, USA. mpalanki@signalpharm.com, Gayo-Fung LM, Shevlin GI, Erdman P, Sato M, Goldman M, Ransone LJ, Spooner C

    المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2002 Sep 16; Vol. 12 (18), pp. 2573-7.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

    مواضيع طبية MeSH: Gene Expression Regulation/*physiology , NF-kappa B/*antagonists & inhibitors , Pyrimidines/*pharmacology , Pyrroles/*pharmacology , Transcription Factor AP-1/*antagonists & inhibitors, Humans ; Jurkat Cells ; NF-kappa B/physiology ; Pyrimidines/chemistry ; Pyrroles/chemistry ; Structure-Activity Relationship ; Transcription Factor AP-1/physiology

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  3. 3
    دورية أكاديمية
    Inhibitors of NF-kappaB and AP-1 gene expression: SAR studies on the pyrimidine portion of 2-chloro-4-trifluoromethylpyrimidine-5-[N-(3', 5'-bis(trifluoromethyl)phenyl)carboxamide].

    المؤلفون: Palanki MS; Signal Pharmaceuticals, Inc., 5555 Oberlin Drive, San Diego, California 92121, USA. mpalanki@signalpharm.com, Erdman PE, Gayo-Fung LM, Shevlin GI, Sullivan RW, Goldman ME, Ransone LJ, Bennett BL, Manning AM, Suto MJ

    المصدر: Journal of medicinal chemistry [J Med Chem] 2000 Oct 19; Vol. 43 (21), pp. 3995-4004.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

    مواضيع طبية MeSH: NF-kappa B/*antagonists & inhibitors , Pyrimidines/*chemical synthesis , Pyrimidines/*chemistry , Transcription Factor AP-1/*antagonists & inhibitors, Animals ; Caco-2 Cells ; Cell Membrane Permeability/drug effects ; Combinatorial Chemistry Techniques ; Cricetinae ; Humans ; Jurkat Cells ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Pyrimidines/pharmacology ; Structure-Activity Relationship ; Transcription Factor AP-1/genetics ; Transcription Factor AP-1/metabolism ; Transfection

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  4. 4
    دورية أكاديمية
    Novel inhibitors of AP-1 and NF-kappaB mediated gene expression: structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)++ +pyrimidi ne-5-carboxylate.

    المؤلفون: Palanki MS; Signal Pharmaceuticals, Inc., San Diego, CA 92121, USA. mpalanki@signalpharm.com, Erdman PE, Manning AM, Ow A, Ransone LJ, Spooner C, Suto C, Suto M

    المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2000 Aug 07; Vol. 10 (15), pp. 1645-8.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

    مواضيع طبية MeSH: Gene Expression Regulation/*drug effects , Maleimides/*pharmacology , NF-kappa B/*antagonists & inhibitors , Pyrimidines/*pharmacology , Transcription Factor AP-1/*antagonists & inhibitors, Humans ; Jurkat Cells ; Maleimides/chemistry ; Pyrimidines/chemistry ; Structure-Activity Relationship

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  5. 5
    دورية أكاديمية
    2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3',5'- bis(trifluoromethyl)phenyl)-carboxamide: a potent inhibitor of NF-kappa B- and AP-1-mediated gene expression identified using solution-phase combinatorial chemistry.

    المؤلفون: Sullivan RW; Department of Medicinal Chemistry, Signal Pharmaceuticals, Inc., San Diego, California 92121, USA., Bigam CG, Erdman PE, Palanki MS, Anderson DW, Goldman ME, Ransone LJ, Suto MJ

    المصدر: Journal of medicinal chemistry [J Med Chem] 1998 Feb 12; Vol. 41 (4), pp. 413-9.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

    مواضيع طبية MeSH: Cytokines/*biosynthesis , Gene Expression Regulation/*drug effects , NF-kappa B/*antagonists & inhibitors , Pyrimidines/*chemical synthesis , Transcription Factor AP-1/*antagonists & inhibitors, Actins/biosynthesis ; Animals ; Humans ; Immunosuppression Therapy ; Inflammation ; Interleukin-2/biosynthesis ; Interleukin-8/biosynthesis ; Jurkat Cells ; Luciferases/biosynthesis ; Molecular Structure ; Pyrimidines/chemistry ; Pyrimidines/pharmacokinetics ; Recombinant Fusion Proteins/antagonists & inhibitors ; Structure-Activity Relationship ; Tetradecanoylphorbol Acetate/pharmacology ; Transfection

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  6. 6
    دورية أكاديمية
    SP100030 is a novel T-cell-specific transcription factor inhibitor that possesses immunosuppressive activity in vivo.

    المؤلفون: Goldman ME; Department of Pharmacology, Signal Pharmaceuticals, Inc, San Diego, California 92121, USA. mgoldman@signalpharm.com, Ransone LJ, Anderson DW, Gaarde WA, Suto MJ, Sullivan RW, Shorthouse R, Morikawa M, Morris RE

    المصدر: Transplantation proceedings [Transplant Proc] 1996 Dec; Vol. 28 (6), pp. 3106-9.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print Cited Medium: Print ISSN: 0041-1345 (Print) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE

    مواضيع طبية MeSH: Lymphocyte Transfusion*, Arthritis, Experimental/*immunology , Heart Transplantation/*immunology , Immunosuppressive Agents/*pharmacology , Lymph Nodes/*immunology , Lymphocytes/*immunology, Animals ; Arthritis, Experimental/prevention & control ; Body Weight/drug effects ; Dexamethasone/pharmacology ; Female ; Hyperplasia ; Isoantigens/immunology ; Lymph Nodes/pathology ; Lymphocytes/drug effects ; Lymphocytes/radiation effects ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C3H ; Organic Chemicals ; Rats ; Rats, Inbred Lew ; Spleen ; Transplantation, Heterotopic

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  7. 7
    دورية أكاديمية
    Detection of protein-protein interactions by coimmunoprecipitation and dimerization.

    المؤلفون: Ransone LJ; Signal Pharmaceuticals, Incorporated, San Diego, California 92121, USA.

    المصدر: Methods in enzymology [Methods Enzymol] 1995; Vol. 254, pp. 491-7.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

    بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print Cited Medium: Print ISSN: 0076-6879 (Print) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

    مواضيع طبية MeSH: Oncogene Proteins/*chemistry , Oncogene Proteins/*metabolism , Transcription Factors/*metabolism, Animals ; Cell Nucleus/metabolism ; Chemical Precipitation ; Chromatography, Affinity/methods ; Cross-Linking Reagents ; Electrophoresis, Polyacrylamide Gel/methods ; Glutaral ; Immunologic Techniques ; Macromolecular Substances ; Methionine/metabolism ; Oncogene Proteins/analysis ; Protein Biosynthesis ; Rabbits ; Reticulocytes/metabolism ; Sulfur Radioisotopes ; Transcription Factors/analysis ; Triticum/metabolism

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  8. 8
    دورية أكاديمية
    Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B.

    المؤلفون: Kerr LD; Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92138., Ransone LJ, Wamsley P, Schmitt MJ, Boyer TG, Zhou Q, Berk AJ, Verma IM

    المصدر: Nature [Nature] 1993 Sep 30; Vol. 365 (6445), pp. 412-9.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

    بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Print ISSN: 0028-0836 (Print) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

    مواضيع طبية MeSH: Transcription, Genetic*, DNA-Binding Proteins/*metabolism , NF-kappa B/*metabolism , Proto-Oncogene Proteins/*metabolism , Transcription Factors/*metabolism, Animals ; Base Sequence ; Cell Line ; Drosophila ; Enhancer Elements, Genetic ; Escherichia coli ; HeLa Cells ; Humans ; Molecular Sequence Data ; Mutation ; Oligodeoxyribonucleotides ; Precipitin Tests ; Protein Binding ; Proto-Oncogene Proteins c-rel ; Recombinant Proteins ; Saccharomyces cerevisiae/genetics ; TATA-Box Binding Protein ; Transcription Factor TFIID ; Transcriptional Activation ; Transfection

    Find this article in full text from ProQuest Full Text Finder
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  9. 9
    دورية أكاديمية
    The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein.

    المؤلفون: Ransone LJ; Molecular Biology and Virology Laboratory, Salk Institute, San Diego, CA 85800., Kerr LD, Schmitt MJ, Wamsley P, Verma IM

    المصدر: Gene expression [Gene Expr] 1993; Vol. 3 (1), pp. 37-48.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

    بيانات الدورية: Publisher: Cognizant Communications Country of Publication: United States NLM ID: 9200651 Publication Model: Print Cited Medium: Print ISSN: 1052-2166 (Print) Linking ISSN: 10522166 NLM ISO Abbreviation: Gene Expr Subsets: MEDLINE

    مواضيع طبية MeSH: DNA-Binding Proteins/*metabolism , Proto-Oncogene Proteins c-fos/*metabolism , Proto-Oncogene Proteins c-jun/*metabolism , Transcription Factors/*metabolism, Amino Acid Sequence ; Binding Sites ; Humans ; Leucine Zippers/genetics ; Leucine Zippers/physiology ; Molecular Sequence Data ; Point Mutation ; Proto-Oncogene Proteins c-fos/genetics ; Proto-Oncogene Proteins c-jun/genetics ; RNA/biosynthesis ; TATA Box ; TATA-Box Binding Protein ; Transcription, Genetic

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  10. 10
    دورية أكاديمية
    Transformation by Jun: requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos.

    المؤلفون: Morgan IM; Department of Microbiology, University of Southern California School of Medicine, Los Angeles., Ransone LJ, Bos TJ, Verma IM, Vogt PK

    المصدر: Oncogene [Oncogene] 1992 Jun; Vol. 7 (6), pp. 1119-25.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

    بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232 (Print) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

    مواضيع طبية MeSH: Genes, fos* , Genes, jun*, Cell Transformation, Neoplastic/*genetics , Leucine Zippers/*genetics , Proto-Oncogene Proteins c-fos/*genetics , Proto-Oncogene Proteins c-jun/*genetics, Amino Acid Sequence ; Animals ; Blotting, Western ; Cells, Cultured ; Chick Embryo ; Chickens ; Chloramphenicol O-Acetyltransferase/genetics ; Chloramphenicol O-Acetyltransferase/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Protein Biosynthesis ; Protein Conformation ; Transcription, Genetic ; Transcriptional Activation ; Transfection

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