المؤلفون: Cm, Lindgren, Im, Heid, Jc, Randall, Lamina C, Steinthorsdottir V, Qi L, Ek, Speliotes, Thorleifsson G, Cj, Willer, Bm, Herrera, Au, Jackson, Lim N, Scheet P, Soranzo N, Amin N, Ys, Aulchenko, Jc, Chambers, Drong A, Luan J, Hn, Lyon, Rivadeneira F, Sanna S, Nj, Timpson, Mc, Zillikens, Jh, Zhao, Almgren P, Bandinelli S, Aj, Bennett, Rn, Bergman, Ll, Bonnycastle, Sj, Bumpstead, Sj, Chanock, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Asf, Doney, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Ng, Forouhi, Gieger C, Grallert H, Cj, Groves, Grundy S, Guiducci C, Hadley D, Hamsten A, As, Havulinna, Hofman A, Holle R, Jw, Holloway, Illig T, Isomaa B, Lc, Jacobs, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Gm, Lathrop, Da, Lawlor, Mangino M, Wl, Mcardle, Meitinger T, Ma, Morken, Ap, Morris, Munroe P, Narisu N, Nordström A, Nordström P, Ba, Oostra, Cna, Palmer, Payne F, Jf, Peden, Inga Prokopenko, Renström F, Ruokonen A, Salomaa V, Ms, Sandhu, Lj, Scott, Scuteri A, Silander K, Song K, Yuan X, Hm, Stringham, Aj, Swift, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Gb, Walters, Mn, Weedon, Jcm, Witteman, Zhang C, Zhang W, Mj, Caulfield, Fs, Collins, Davey Smith G, Inm, Day, Pw, Franks, At, Hattersley, Fb, Hu, Jarvelin M, Kong A, Js, Kooner, Laakso M, Lakatta E, Mooser V, Ad, Morris, Peltonen L, Nj, Samani, Td, Spector, Dp, Strachan, Tanaka T, Tuomilehto J, Ag, Uitterlinden, Cm, Duijn, Nj, Wareham, Procardis, Watkins For The Consortia H., Dm, Waterworth, Boehnke M, Deloukas P, Groop L, Dj, Hunter, Thorsteinsdottir U, Schlessinger D, H-, Wichmann, Tm, Frayling, Gr, Abecasis, Jn, Hirschhorn, Rjf, Loos, Stefansson K, Kl, Mohlke, Barroso I, Giant Mi, Mccarthy For The Consortium

المصدر: Europe PubMed Central
PLoS Genetics
PLoS Genetics, Vol 5, Iss 7 (2009)

مصطلحات موضوعية: lcsh:Genetics, 0303 health sciences, 03 medical and health sciences, Cancer Research, 0302 clinical medicine, lcsh:QH426-470, Genetics, Correction, 030209 endocrinology & metabolism, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4aa71e313de404e331242e6d0f0e4f
http://europepmc.org/abstract/PMC/PMC2722420

المؤلفون: Grenko CM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN, USA., Taylor HJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. hjt52@cam.ac.uk.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. hjt52@cam.ac.uk.; Heart and Lung Research Institute, University of Cambridge, Cambridge, UK. hjt52@cam.ac.uk., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Xue D; Department of Surgery, Weill Cornell Medicine, New York, NY, USA.; Center for Genomic Health, Weill Cornell Medicine, New York, NY, USA., Lee BN; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Weiss Z; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Yan T; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Swift AJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Mansell EC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Lee A; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Robertson CC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY, USA.; Center for Genomic Health, Weill Cornell Medicine, New York, NY, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. francis.collins@nih.gov., Taylor DL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

المصدر: Diabetologia [Diabetologia] 2024 Jul 05. Date of Electronic Publication: 2024 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

المؤلفون: Jovanovic VM, Narisu N, Bonnycastle LL, Tharakan R, Mesch KT, Glover HJ, Yan T, Sinha N, Sen C, Castellano D, Yang S, Blivis D, Ryu S, Bennett DF, Rosales-Soto G, Inman J, Ormanoglu P, LeClair CA, Xia M, Schneider M, Hernandez-Ochoa EO, Erdos MR, Simeonov A, Chen S, Singeç I, Collins FS, Doege CA, Tristan CA

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 02. Date of Electronic Publication: 2024 Jul 02.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Swift AJ; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Mansell EC; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Lee A; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Winnicki E; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Li ES; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Robertson CC; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Parsons VA; Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Huynh T; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Krilow C; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Mohlke KL; Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.

المصدر: The CRISPR journal [CRISPR J] 2024 Feb; Vol. 7 (1), pp. 53-67.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101738191 Publication Model: Print Cited Medium: Internet ISSN: 2573-1602 (Electronic) Linking ISSN: 25731599 NLM ISO Abbreviation: CRISPR J Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2* , Induced Pluripotent Stem Cells*, Humans ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; CRISPR-Cas Systems/genetics ; Gene Editing ; RNA, Guide, CRISPR-Cas Systems

المؤلفون: Xue D; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Taylor DL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Zhang M; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Grenko C; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Taylor HJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN Cambridge, UK., Yan T; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Tang X; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Sinha N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Zhu J; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Vandana JJ; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, The Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Nok Chong AC; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Lee A; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Mansell EC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Swift AJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Zhong A; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Zhou T; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Center for Genomic Health, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA. Electronic address: shc2034@med.cornell.edu., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: francis.collins@nih.gov.

المصدر: Cell metabolism [Cell Metab] 2023 Nov 07; Vol. 35 (11), pp. 1897-1914.e11. Date of Electronic Publication: 2023 Oct 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/metabolism , Human Embryonic Stem Cells*/metabolism , Insulin-Secreting Cells*/metabolism, Humans ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide ; Carbonyl Reductase (NADPH)/genetics ; Carbonyl Reductase (NADPH)/metabolism

المؤلفون: Brotman SM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., El-Sayed Moustafa JS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Guan L; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Wang D; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Welch R; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Currin KW; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Tomlinson M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Medical and Molecular Genetics, King's College London, London, UK., Vadlamudi S; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Roberts AL; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Oravilahti A; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland., Silva LF; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Yan T; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raza Y; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Yan X; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Parker SCJ; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Kuusisto J; Department of Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland., Pajukanta P; Department of Human Genetics and Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Tuomilehto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Love MI; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA., Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Laakso M; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.; Department of Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 27. Date of Electronic Publication: 2023 Oct 27.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Hudaiberdiev S; Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20892., Taylor DL; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Song W; Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20892., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Bhuiyan RM; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032.; Department of Genetics and Genome Sciences, University of Connecticut, Farmington, CT 06032., Taylor HJ; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Tang X; Department of Surgery, Weill Cornell Medicine, New York, NY 10065.; Center for Genomic Health, Weill Cornell Medicine, New York, NY 10065., Yan T; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Swift AJ; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Consortium D, Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY 10065.; Center for Genomic Health, Weill Cornell Medicine, New York, NY 10065., Stitzel ML; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032.; Department of Genetics and Genome Sciences, University of Connecticut, Farmington, CT 06032.; Institute of Systems Genomics, University of Connecticut, Farmington, CT 06032., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892., Ovcharenko I; Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, MD 20892., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD 20892.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 29; Vol. 120 (35), pp. e2206612120. Date of Electronic Publication: 2023 Aug 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/pathology , Deep Learning* , Enhancer Elements, Genetic* , Islets of Langerhans*/metabolism , Islets of Langerhans*/pathology, Genetic Variation ; Humans ; Computer Simulation

المؤلفون: Grenko CM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Taylor HJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Yan T; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Swift AJ; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Robertson CC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA., Taylor DL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 17. Date of Electronic Publication: 2023 Jul 17.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Tenney AP; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA., Di Gioia SA; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Webb BD; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chan WM; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., de Boer E; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., Garnai SJ; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Harvard-MIT Health Sciences and Technology, Harvard Medical School, Boston, MA, USA., Barry BJ; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Ray T; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Kosicki M; Environmental Genomics & System Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Robson CD; Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Zhang Z; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Collins TE; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Gelber A; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Pratt BM; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Fujiwara Y; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA., Varshney A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Lek M; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA., Warburton PE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Advanced Genomics Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Van Ryzin C; Metabolic Medicine Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Lehky TJ; EMG Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Zalewski C; Audiology Unit, Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, MD, USA., King KA; Audiology Unit, Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, MD, USA., Brewer CC; Audiology Unit, Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, MD, USA., Thurm A; Neurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, NIH, Bethesda, MD, USA., Snow J; Office of the Clinical Director, National Institute of Mental Health, NIH, Bethesda, MD, USA., Facio FM; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA.; Invitae Corporation, San Francisco, CA, USA., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Swift A; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Chines PS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bell JL; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Mohan S; Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA., Whitman MC; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Staffieri SE; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, and University of Melbourne, Melbourne, Victoria, Australia.; Department of Ophthalmology, Royal Children's Hospital, Parkville, Victoria, Australia., Elder JE; Department of Ophthalmology, Royal Children's Hospital, Parkville, Victoria, Australia., Demer JL; Stein Eye Institute and Departments of Ophthalmology, Neurology, and Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA., Torres A; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatrics, Boston Medical Center, Boston University Aram V. Chobanian & Edward Avedisian School of Medicine, Boston, MA, USA., Rachid E; Department of Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon., Al-Haddad C; Department of Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon., Boustany RM; Pediatrics & Adolescent Medicine/Biochemistry & Molecular Genetics, American University of Beirut Medical Center, Beirut, Lebanon., Mackey DA; Lions Eye Institute, University of Western Australia, Perth, Australia., Brady AF; North West Thames Regional Genetics Service, Northwick Park Hospital, Harrow, UK., Fenollar-Cortés M; Unidad de Genética Clínica, Instituto de Medicina del Laboratorio. IdISSC, Hospital Clínico San Carlos, Madrid, Spain., Fradin M; Service de Génétique Clinique, CHU Rennes, Centre Labellisé Anomalies du Développement, Rennes, France., Kleefstra T; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Center of Excellence for Neuropsychiatry, Vincent van Gogh Institute for Psychiatry, Venray, the Netherlands., Padberg GW; Department of Neurology, Radboud University Medical Center, Nijmegen, the Netherlands., Raskin S; Centro de Aconselhamento e Laboratório Genetika, Curitiba, Paraná, Brazil., Sato MT; Department of Ophthalmology & Otorhinolaryngology, Federal University of Paraná, Curitiba, Paraná, Brazil., Orkin SH; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA., Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Hadlock TA; Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA., Vissers LELM; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., van Bokhoven H; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., Jabs EW; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Pennacchio LA; Environmental Genomics & System Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Manoli I; Metabolic Medicine Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Engle EC; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. elizabeth.engle@childrens.harvard.edu.; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.

المصدر: Nature genetics [Nat Genet] 2023 Jul; Vol. 55 (7), pp. 1149-1163. Date of Electronic Publication: 2023 Jun 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Facial Paralysis*/genetics , Facial Paralysis*/congenital , Facial Paralysis*/metabolism, Animals ; Mice ; GATA2 Transcription Factor/genetics ; GATA2 Transcription Factor/metabolism ; Motor Neurons/metabolism ; Neurogenesis ; Neurons, Efferent

المؤلفون: Williamson A; MRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.; Metabolic Research Laboratories Wellcome Trust-MRC Institute of Metabolic Science, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK., Norris DM; Metabolic Research Laboratories Wellcome Trust-MRC Institute of Metabolic Science, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK., Yin X; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China., Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moxley AH; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Vadlamudi S; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Wilson EP; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ahuja V; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Arzumanyan Z; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Bonnycastle LL; Center for Precision Health Research National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bornstein SR; Department of Internal Medicine III, Metabolic and Vascular Medicine, Medical Faculty Carl Gustav Carus, Dresden, Germany.; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Bretschneider MP; Department of Internal Medicine III, Metabolic and Vascular Medicine, Medical Faculty Carl Gustav Carus, Dresden, Germany.; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Buchanan TA; Department of Medicine, Division of Endocrinology and Diabetes, Keck School of Medicine USC, Los Angeles, CA, USA., Chang YC; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei City, Taiwan.; Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei City, Taiwan., Chuang LM; Department of Internal Medicine, Division of Endocrinology and Metabolism, National Taiwan University Hospital, Taipei City, Taiwan., Chung RH; Institute of Population Health Sciences, National Health Research Institutes, Toufen, Taiwan., Clausen TD; Department of Gynecology and Obstetrics, Nordsjaellands Hospital, Hillerød, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Damm P; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Pregnant Women with Diabetes, Rigshospitalet, Copenhagen, Denmark.; Department of Obstetrics, Rigshospitalet, Copenhagen, Denmark., Delgado GE; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., de Mello VD; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Quebec, Canada., Dwivedi OP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Erdos MR; Center for Precision Health Research National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Fernandes Silva L; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Frayling TM; University of Exeter Medical School University of Exeter, Exeter, UK., Gieger C; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Goodarzi MO; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism Cedars-Sinai Medical Center, Los Angeles, CA, USA., Guo X; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Gustafsson S; Department of Medical Sciences, Clinical Epidemiology, Uppsala University, Uppsala, Sweden., Hakaste L; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Hammar U; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Hatem G; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Malmö, Sweden., Herrmann S; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; Department of Internal Medicine III, Prevention and Care of Diabetes, Medical Faculty Carl Gustav Carus, Dresden, Germany., Højlund K; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark., Horn K; Medical Faculty Institute for Medical Informatics, Statistics and Epidemiology, Leipzig, Germany.; LIFE Leipzig Research Center for Civilization Diseases, Medical Faculty, Leipzig, Germany., Hsueh WA; Internal Medicine, Endocrinology, Diabetes and Metabolism, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Hung YJ; Institute of Preventive Medicine, National Defense Medical Center, New Taipei City, Taiwan., Hwu CM; Department of Medicine Section of Endocrinology and Metabolism, Taipei Veterans General Hospital, Taipei City, Taiwan., Jonsson A; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kårhus LL; Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark., Kleber ME; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.; SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany., Kovacs P; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Lauzon M; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Lee IT; Department of Internal Medicine Division of Endocrinology and Metabolism, Taichung Veterans General Hospital, Taichung City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung City, Taiwan., Lindgren CM; Big Data Institute Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK.; Broad Institute, Cambridge, MA, USA., Lindström J; Finnish Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Luan J; MRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Aly DM; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Malmö, Sweden., Mathiesen E; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Pregnant Women with Diabetes, Rigshospitalet, Copenhagen, Denmark.; Department of Endocrinology Rigshospitalet, Copenhagen, Denmark., Moissl AP; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.; Institute of Nutritional Sciences, Friedrich-Schiller-University, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena, Jena, Germany., Morris AP; Centre for Genetics and Genomics Versus Arthritis Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., Narisu N; Center for Precision Health Research National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Perakakis N; Department of Internal Medicine III, Metabolic and Vascular Medicine, Medical Faculty Carl Gustav Carus, Dresden, Germany.; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Peters A; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Prasad RB; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Malmö, Sweden., Rodionov RN; Department of Internal Medicine III, University Center for Vascular Medicine, Medical Faculty Carl Gustav Carus, Dresden, Germany.; College of Medicine and Public Health, Flinders University and Flinders Medical Centre, Adelaide, Australia., Roll K; Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rundsten CF; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sarnowski C; Department of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center, Houston, TX, USA., Savonen K; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Scholz M; Medical Faculty Institute for Medical Informatics, Statistics and Epidemiology, Leipzig, Germany.; LIFE Leipzig Research Center for Civilization Diseases, Medical Faculty, Leipzig, Germany., Sharma S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Food Chemistry and Molecular and Sensory Science, Technical University of Munich, Freising-Weihenstephan, München, Germany., Stinson SE; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Suleman S; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tan J; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Taylor KD; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Vistisen D; Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Witte DR; Steno Diabetes Center Aarhus, Aarhus, Denmark.; Department of Public Health, Aarhus University, Aarhus, Denmark., Walther R; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; Department of Internal Medicine III, Pathobiochemistry, Medical Faculty Carl Gustav Carus, Dresden, Germany., Wu P; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Xiang AH; Research and Evaluation, Division of Biostatistics, Kaiser Permanente Southern California, Pasadena, CA, USA., Zethelius B; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Ahlqvist E; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Malmö, Sweden., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Chen YI; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Collins FS; Center for Precision Health Research National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Fall T; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Florez JC; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, The Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Fritsche A; Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany., Grallert H; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Groop L; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Lund, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Lind L; Department of Medical Sciences, Clinical Epidemiology, Uppsala University, Uppsala, Sweden., Loeffler M; Medical Faculty Institute for Medical Informatics, Statistics and Epidemiology, Leipzig, Germany.; LIFE Leipzig Research Center for Civilization Diseases, Medical Faculty, Leipzig, Germany., März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Synlab Academy, SYNLAB Holding Deutschland GmbH, Mannheim, Germany., Meigs JB; Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany.; Clinical Sciences Malmö, Genomics, Diabetes and Endocrinology, Lund University, Lund, Sweden.; Department of Medicine Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Raffel LJ; Department of Pediatrics, Genetic and Genomic Medicine, University of California, Irvine, CA, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Schwarz PEH; Helmholtz Zentrum München Paul Langerhans Institute Dresden (PLID), University Hospital and Faculty of Medicine TU Dresden, Dresden, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Department of Internal Medicine III, Prevention and Care of Diabetes, Medical Faculty Carl Gustav Carus, Dresden, Germany., Stumvoll M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Sundström J; Department of Medical Sciences, Clinical Epidemiology, Uppsala University, Uppsala, Sweden., Tönjes A; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Tuomi T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Tuomilehto J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Wagner R; Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany., Barroso I; Exeter Centre of Excellence for Diabetes Research (EXCEED), Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Walker M; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Wareham NJ; MRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA. karen_mohlke@med.unc.edu., Wheeler E; MRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK. eleanor.wheeler@mrc-epid.cam.ac.uk., O'Rahilly S; Metabolic Research Laboratories Wellcome Trust-MRC Institute of Metabolic Science, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK. so104@medschl.cam.ac.uk., Fazakerley DJ; Metabolic Research Laboratories Wellcome Trust-MRC Institute of Metabolic Science, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK. djf72@cam.ac.uk., Langenberg C; MRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK. claudia.langenberg@qmul.ac.uk.; Computational Medicine, Berlin Institute of Health at Charité-Universitätsmedizin, Berlin, Germany. claudia.langenberg@qmul.ac.uk.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. claudia.langenberg@qmul.ac.uk.

مؤلفون مشاركون: Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC)

المصدر: Nature genetics [Nat Genet] 2023 Jun; Vol. 55 (6), pp. 973-983. Date of Electronic Publication: 2023 Jun 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Insulin Resistance*/genetics , Diabetes Mellitus, Type 2*/genetics, Humans ; Insulin/genetics ; Genome-Wide Association Study ; Glucose/metabolism ; Blood Glucose/genetics