المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras

المصدر: Journal of Medicinal Chemistry. 48:6779-6782

مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc05f6b9f812322c1ff557485178cfdb
https://doi.org/10.1021/jm050307e

المؤلفون: Ding I. Yang, Jiu Haw Yin, Long Shiuh Chen, Tzyh Chwen Ju, Chung Y. Hsu

المصدر: Free Radical Biology and Medicine. 36:1317-1328

مصطلحات موضوعية: Alkylation, Nitric Oxide Synthase Type II, Nitric Oxide, Biochemistry, Antioxidants, Nitric oxide, S-Nitrosoglutathione, chemistry.chemical_compound, Physiology (medical), Glioma, parasitic diseases, Tumor Cells, Cultured, medicine, Animals, Buthionine sulfoximine, Cytotoxicity, Antineoplastic Agents, Alkylating, Chelating Agents, Carmustine, biology, Chemistry, Glutathione, medicine.disease, Rats, Nitric oxide synthase, Drug Resistance, Neoplasm, Cancer research, biology.protein, Carbamates, Nitric Oxide Synthase, Phenanthrolines, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357efb03b261cda1986008698ff7f5e1
https://doi.org/10.1016/j.freeradbiomed.2004.02.010

المؤلفون: Niel C. Hoglen, Patricia C. Contreras, Brad P. Hirakawa, Long-Shiuh Chen, Todd Groessl, Craig D. Fisher

المصدر: Journal of Pharmacology and Experimental Therapeutics. 309:634-640

مصطلحات موضوعية: Male, Pharmacology, Rats, Sprague-Dawley, Mice, Liver disease, Pharmacokinetics, In vivo, Oral administration, medicine, Animals, Potency, Enzyme Inhibitors, Pentanoic Acids, Caspase, Liver injury, Mice, Inbred BALB C, biology, business.industry, medicine.disease, Caspase Inhibitors, Rats, Apoptosis, Models, Animal, biology.protein, Molecular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cd6072fda815132c80b024022dc888
https://doi.org/10.1124/jpet.103.062034

المؤلفون: Mark B. Judkins, Stanley C. Gill, Long-Shiuh Chen, Chris Tucker, Daniel W. Drolet, James A. Farmer

المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 732:203-212

مصطلحات موضوعية: Quality Control, Vascular Endothelial Growth Factor A, Angiogenesis, Injections, Subcutaneous, Aptamer, Oligonucleotides, Endothelial Growth Factors, Polyethylene glycol, chemistry.chemical_compound, Drug Stability, Pharmacokinetics, Blood plasma, Animals, Humans, Chromatography, High Pressure Liquid, Lymphokines, Chromatography, Vascular Endothelial Growth Factors, Chemistry, Reproducibility of Results, General Chemistry, Macaca mulatta, In vitro, Vascular endothelial growth factor, Injections, Intravenous, Quantitative analysis (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd7c27c6305d85c906115d8f32a28f
https://doi.org/10.1016/s0378-4347(99)00285-6

المؤلفون: James M. Fujitaki, Ross Dixon, Heather M. Grettenberger, Long-Shiuh Chen

المصدر: Journal of Biochemical and Biophysical Methods. 33:25-30

مصطلحات موضوعية: Drug, Detection limit, Chromatography, Chemistry, media_common.quotation_subject, Biophysics, Cardiovascular Agents, Deoxyribonucleosides, Aminoimidazole Carboxamide, Biochemistry, High-performance liquid chromatography, Spectrophotometry, Human plasma, Plasma concentration, Humans, Colorimetry, Cardioprotective Agent, Chromatography, High Pressure Liquid, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5a68ca6b58ca775631d751380dddb6
https://doi.org/10.1016/0165-022x(96)00011-5

المؤلفون: Ross Dixon, James M. Fujitaki, Long-Shiuh Chen

المصدر: Journal of Pharmaceutical and Biomedical Analysis. 14:1535-1538

مصطلحات موضوعية: Detection limit, Chromatography, Working electrode, Chemistry, Clinical Biochemistry, Pharmaceutical Science, Deoxyribonucleosides, Haplorhini, Reversed-phase chromatography, Glassy carbon, Aminoimidazole Carboxamide, Phosphate, Sensitivity and Specificity, Amperometry, Rats, Analytical Chemistry, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, Electrochemistry, Animals, Quantitative analysis (chemistry), Spectroscopy, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9853716f4fdd35ad9ed8a8865d84aa2b
https://doi.org/10.1016/0731-7085(95)01719-4

المؤلفون: Ross Dixon, James M. Fujttaki, Long-Shiuh Chen

المصدر: Journal of Liquid Chromatography. 18:1451-1457

مصطلحات موضوعية: Detection limit, chemistry.chemical_compound, Chromatography, Working electrode, chemistry, Acadesine, Elution, Molecular Medicine, Methanol, Quantitative analysis (chemistry), High-performance liquid chromatography, Amperometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aea9e85094444162c0d27fb068a35cbe
https://doi.org/10.1080/10826079508010423

المؤلفون: Michael L. Klein, Jerry Bill, Morton F. Goldberg, Mark Blumenkrantz, Samir C. Patel, Joan W. Miller, Dwight Henninger, Blake Tomkinson, Lawrence A. Yannuzzi, Laurie B. Wiegand, David R. Guyer, Long Shiuh Chen, Daniel F. Martin, Daniel W. Drolet, Stanley C. Gill, Denis O'Shaughnessy, Julia A. Haller, Anthony P. Adamis, Raymond A. Bendele, Evangelos S. Gragoudas

المصدر: Retina (Philadelphia, Pa.). 22(2)

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, Pathology, Skin Neoplasms, Angiogenesis, Pegaptanib, Drug Evaluation, Preclinical, Oligonucleotides, Endothelial Growth Factors, Retinal Neovascularization, chemistry.chemical_compound, Macular Degeneration, Mice, Medicine, Fluorescein Angiography, Skin, Anti vegf, Aged, 80 and over, Lymphokines, Vascular Endothelial Growth Factors, General Medicine, Exudates and Transudates, Middle Aged, Vascular endothelial growth factor, Female, Rabbits, Clinical evaluation, medicine.drug, Half-Life, medicine.medical_specialty, Aptamer, Guinea Pigs, Biological Availability, Mice, Nude, Injections, Capillary Permeability, Pegaptanib Sodium, Animals, Humans, Corneal Neovascularization, Retinopathy of Prematurity, Aged, business.industry, Infant, Newborn, Exudative age-related macular degeneration, Choroidal Neovascularization, Rats, Vitreous Body, Ophthalmology, chemistry, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a08633a57e5156307a8cba91b1dca81
https://pubmed.ncbi.nlm.nih.gov/11927845

المؤلفون: Niel C. Hoglen, Long-Shiuh Chen, Craig D. Fisher, Patricia C. Contreras, Karen L. Valentino

المصدر: Hepatology. 38:580-581

مصطلحات موضوعية: Clinical trial, Caspase inhibitors, Hepatology, Pharmacokinetics, business.industry, Apoptosis, Medicine, Tissue distribution, Pharmacology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::edf5c59ca3952746eb2181149167ad2f
https://doi.org/10.1016/s0270-9139(03)80916-3

المؤلفون: C, Hoglen Niel, Long-Shiuh, Chen, D, Fisher Craig, P, Hirakawa Brad, Todd, Groessl, C, Contreras Patricia

المصدر: The Journal of Pharmacology and Experimental Therapeutics; May 2004, Vol. 309 Issue: 2 p634-40, 7p