المؤلفون: Ortiz G; Department of Cellular and Molecular Pharmacology, University of California San Francisco San Francisco CA 94158 USA danica.fujimori@ucsf.edu., Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California San Francisco San Francisco CA 94158 USA danica.fujimori@ucsf.edu., Qin SL; Department of Cellular and Molecular Pharmacology, University of California San Francisco San Francisco CA 94158 USA danica.fujimori@ucsf.edu., Zhang MY; Department of Cellular and Molecular Pharmacology, University of California San Francisco San Francisco CA 94158 USA danica.fujimori@ucsf.edu., Lee GM; Small Molecule Discovery Center (SMDC), University of California San Francisco San Francisco CA 94158 USA.; Department of Pharmaceutical Chemistry, University of California San Francisco San Francisco CA 94158 USA., Neitz RJ; Small Molecule Discovery Center (SMDC), University of California San Francisco San Francisco CA 94158 USA.; Department of Pharmaceutical Chemistry, University of California San Francisco San Francisco CA 94158 USA., Kelly MJS; Department of Pharmaceutical Chemistry, University of California San Francisco San Francisco CA 94158 USA., Arkin MR; Small Molecule Discovery Center (SMDC), University of California San Francisco San Francisco CA 94158 USA.; Department of Pharmaceutical Chemistry, University of California San Francisco San Francisco CA 94158 USA., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California San Francisco San Francisco CA 94158 USA danica.fujimori@ucsf.edu.; Department of Pharmaceutical Chemistry, University of California San Francisco San Francisco CA 94158 USA.

المصدر: RSC chemical biology [RSC Chem Biol] 2023 Dec 18; Vol. 5 (3), pp. 209-215. Date of Electronic Publication: 2023 Dec 18 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE

المؤلفون: Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, California 94158, United States., Kelly MJS; Department of Pharmaceutical Chemistry, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, California 94158, United States., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, California 94158, United States.; Department of Pharmaceutical Chemistry, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, California 94158, United States.; Quantitative Biosciences Institute, University of California San Francisco, 1700 Fourth Street, San Francisco, California 94158, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2023 Sep 15; Vol. 18 (9), pp. 1915-1925. Date of Electronic Publication: 2021 Feb 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Histones*/metabolism , Chromatin*, Methylation ; Peptides/chemistry ; Protein Domains ; Protein Binding

المؤلفون: Chen IP; Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA., Longbotham JE; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., McMahon S; Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA., Suryawanshi RK; Gladstone Institutes, San Francisco, CA 94158, USA., Khalid MM; Gladstone Institutes, San Francisco, CA 94158, USA., Taha TY; Gladstone Institutes, San Francisco, CA 94158, USA., Tabata T; Gladstone Institutes, San Francisco, CA 94158, USA., Hayashi JM; Gladstone Institutes, San Francisco, CA 94158, USA., Soveg FW; Gladstone Institutes, San Francisco, CA 94158, USA., Carlson-Stevermer J; Synthego Corporation, 3696 Haven Avenue, Suite A, Menlo Park, CA 94063, USA., Gupta M; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA., Zhang MY; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Lam VL; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Li Y; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Yu Z; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Titus EW; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Diallo A; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Oki J; Synthego Corporation, 3696 Haven Avenue, Suite A, Menlo Park, CA 94063, USA., Holden K; Synthego Corporation, 3696 Haven Avenue, Suite A, Menlo Park, CA 94063, USA., Krogan N; Gladstone Institutes, San Francisco, CA 94158, USA; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA., Fujimori DG; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: danica.fujimori@ucsf.edu., Ott M; Gladstone Institutes, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute COVID-19 Research Group (QCRG), University of California, San Francisco, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: melanie.ott@gladstone.ucsf.edu.

المصدر: Cell reports [Cell Rep] 2022 Jul 19; Vol. 40 (3), pp. 111088. Date of Electronic Publication: 2022 Jun 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Angiotensin-Converting Enzyme 2 ; Animals ; Antiviral Agents/pharmacology ; Interferons ; Mice ; Nuclear Proteins ; Transcription Factors ; Viral Proteins

المؤلفون: Chen IP, Longbotham JE, McMahon S, Suryawanshi RK, Carlson-Stevermer J, Gupta M, Zhang MY, Soveg FW, Hayashi JM, Taha TY, Lam VL, Li Y, Yu Z, Titus EW, Diallo A, Oki J, Holden K, Krogan N, Galonić Fujimori D, Ott M

مؤلفون مشاركون: QCRG Structural Biology Consortium

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2021 Nov 15. Date of Electronic Publication: 2021 Nov 15.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Anderson SE; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States., Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California 94158, United States., O'Kane PT; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States., Ugur FS; Chemistry and Chemical Biology Graduate Program, University of California San Francisco, San Francisco, California 94158, United States., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California 94158, United States.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158, United States.; Quantitative Biosciences Institute, University of California San Francisco, San Francisco, California 94158, United States., Mrksich M; Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.; Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Department of Cell and Developmental Biology, Northwestern University, Evanston, Illinois 60208, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2021 Jan 15; Vol. 16 (1), pp. 205-213. Date of Electronic Publication: 2020 Dec 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Histones/*metabolism , Hypoxia-Inducible Factor-Proline Dioxygenases/*metabolism , Retinoblastoma-Binding Protein 2/*metabolism, Fluorescence Polarization ; Humans ; Ligands

المؤلفون: Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94158, USA., Zhang MY; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94158, USA., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94158, USA; Quantitative Biosciences Institute, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address: Danica.Fujimori@ucsf.edu.

المصدر: Current opinion in chemical biology [Curr Opin Chem Biol] 2020 Aug; Vol. 57, pp. 105-113. Date of Electronic Publication: 2020 Aug 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*/methods, Chromatin/*metabolism , Epigenesis, Genetic/*drug effects , Histone Code/*drug effects, Acetylation/drug effects ; Acetyltransferases/chemistry ; Acetyltransferases/metabolism ; Animals ; Chromatin/chemistry ; Histone Demethylases/chemistry ; Histone Demethylases/metabolism ; Histones/chemistry ; Histones/metabolism ; Humans ; Ligands ; Methylation/drug effects ; Models, Molecular ; Ubiquitin/chemistry ; Ubiquitin/metabolism

المؤلفون: Petronikolou N; Department of Cellular and Molecular Pharmacology , University of California , 600 16th Street, Genentech Hall , San Francisco , California 94158 , United States., Longbotham JE; Department of Cellular and Molecular Pharmacology , University of California , 600 16th Street, Genentech Hall , San Francisco , California 94158 , United States., Fujimori DG; Department of Cellular and Molecular Pharmacology , University of California , 600 16th Street, Genentech Hall , San Francisco , California 94158 , United States.; Department of Pharmaceutical Chemistry , University of California , 600 16th Street, Genentech Hall , San Francisco , California 94158 , United States.

المصدر: Biochemistry [Biochemistry] 2020 Feb 11; Vol. 59 (5), pp. 647-651. Date of Electronic Publication: 2020 Jan 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Histones/*metabolism , Neoplasms/*enzymology , Retinoblastoma-Binding Protein 2/*metabolism, Biocatalysis ; Histones/chemistry ; Humans ; Methylation ; Retinoblastoma-Binding Protein 2/chemistry ; Substrate Specificity

المؤلفون: Petronikolou N; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, United States., Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, United States., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, United States; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, United States. Electronic address: danica.fujimori@ucsf.edu.

المصدر: Methods in enzymology [Methods Enzymol] 2020; Vol. 639, pp. 217-236. Date of Electronic Publication: 2020 Apr 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

مواضيع طبية MeSH: Histone Demethylases*/genetics , Histone Demethylases*/metabolism , Histones*/metabolism, Chromatin/genetics ; Demethylation ; Humans ; Jumonji Domain-Containing Histone Demethylases/genetics ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Protein Processing, Post-Translational

المؤلفون: Delgado M; Department of Physical and Analytical Chemistry, University Jaume I, 12071, Castelló de la Plana, Spain., Görlich S; Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, United Kingdom., Longbotham JE; Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, United Kingdom., Scrutton NS; Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, United Kingdom., Hay S; Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, United Kingdom., Moliner V; Department of Physical and Analytical Chemistry, University Jaume I, 12071, Castelló de la Plana, Spain.; Department of Chemistry, University of Bath, Bath BA2 7AY, United Kingdom., Tuñón I; Department of Physical Chemistry, University of València, 46100, Burjassot, Spain.

المصدر: ACS catalysis [ACS Catal] 2019 May 15; Vol. 7 (5), pp. 3190-3198. Date of Electronic Publication: 2017 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101562209 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2155-5435 (Print) NLM ISO Abbreviation: ACS Catal Subsets: PubMed not MEDLINE

المؤلفون: Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Chio CM; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Dharmarajan V; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Trnka MJ; Department of Pharmaceutical Chemistry, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Torres IO; Chemistry and Chemical Biology Graduate Program, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Goswami D; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Ruiz K; TETRAD Graduate Program, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Burlingame AL; Department of Pharmaceutical Chemistry, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA., Griffin PR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA., Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA. Danica.Fujimori@ucsf.edu.; Department of Pharmaceutical Chemistry, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA. Danica.Fujimori@ucsf.edu.

المصدر: Nature communications [Nat Commun] 2019 Jan 09; Vol. 10 (1), pp. 94. Date of Electronic Publication: 2019 Jan 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Histones/*metabolism , Retinoblastoma-Binding Protein 2/*metabolism, Animals ; Catalytic Domain ; Models, Molecular ; Protein Conformation ; Protein Domains ; Retinoblastoma-Binding Protein 2/genetics ; Sf9 Cells