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المؤلفون: William Farnaby, Louise Dickson, Stephen Robert Mack, William J. Buffham, Daniel Brown, Jonathan Ellery, Philip J. Mitchell, Matt Barnes, Loredana Ciuclan, Richard J. Isaacs, Toni Cheung, Peter Bunyard
المصدر: European Journal of Pharmacology. 833:8-15
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Allosteric modulator, RHOA, biology, Stereochemistry, Allosteric regulation, Antagonist, chemistry.chemical_element, Calcium, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Lysophosphatidic acid, biology.protein, Receptor, Benzoic acid
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المؤلفون: Jonathan, Ellery, Louise, Dickson, Toni, Cheung, Loredana, Ciuclan, Peter, Bunyard, Stephen, Mack, William J, Buffham, William, Farnaby, Philip, Mitchell, Daniel, Brown, Richard, Isaacs, Matt, Barnes
المصدر: European journal of pharmacology. 833
مصطلحات موضوعية: Cyclopropanes, Allosteric Regulation, Indenes, Cell Line, Tumor, Benzamides, Cyclic AMP, Animals, Calcium, Receptors, Lysophosphatidic Acid, Benzoates, Oxazoles, Rats
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المؤلفون: Kristin Wahl, Hamed Alborzinia, Heike Bantel, Maria Thomas, Matthias P. Ebert, Loredana Ciuclan, Steven Dooley, Stefan Wölfl, F Wandrer, Katja Breitkopf-Heinlein, Sabrina Ehnert, H Gaitantzi, Andreas K. Nussler, Ina Bergheim, Pia Rakoczy, Christoph Meyer
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-15 (2018)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Immunology, Apoptosis, medicine.disease_cause, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Transforming Growth Factor beta, medicine, Animals, Humans, Ethanol metabolism, lcsh:QH573-671, Protein kinase B, Ethanol, Chemistry, lcsh:Cytology, Acetaldehyde, Cell Biology, CYP2E1, Mice, Inbred C57BL, Crosstalk (biology), 030104 developmental biology, Cancer research, Hepatocytes, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Loredana Ciuclan, Nicholas W. Morrell, Nicholas Duggan, Liqun Dong, Daniel Sutton, Jenny Simmons, Gino Van Heeke, Gerald Dubois, Karen England, Matthew Thomas, Martin Hussey, Kelly-Ann Sheppard, Gabor Jarai, Matthew J. Edwards
المصدر: The American Journal of Pathology. 183:1461-1473
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Indoles, Heart Ventricles, Hypertension, Pulmonary, Endogeny, Bone morphogenetic protein, Article, Pathology and Forensic Medicine, Mice, Downregulation and upregulation, Right ventricular hypertrophy, Internal medicine, medicine, Animals, Humans, Familial Primary Pulmonary Hypertension, Pyrroles, Hypoxia, Lung, business.industry, Hemodynamics, Antagonist, Antibodies, Monoclonal, Hypoxia (medical), medicine.disease, HEK293 Cells, medicine.anatomical_structure, Endocrinology, Ventricle, Bone Morphogenetic Proteins, Chronic Disease, Intercellular Signaling Peptides and Proteins, medicine.symptom, business, Signal Transduction
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المؤلفون: Stephanie J. Harris, Matthew Thomas, Matthias P. Wymann, John Westwick, Peter Finan, Loredana Ciuclan, Christoph Walker, Stephen G. Ward
المصدر: European Journal of Immunology. 42:3394-3404
مصطلحات موضوعية: 0303 health sciences, medicine.medical_treatment, Immunology, Inflammation, Biology, Cell biology, TCIRG1, 03 medical and health sciences, 0302 clinical medicine, Immune system, Cytokine, In vivo, medicine, Immunology and Allergy, Phosphorylation, Interleukin 17, medicine.symptom, Protein kinase B, 030304 developmental biology, 030215 immunology
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المؤلفون: Mark Southwood, James Iremonger, Josephine A. Pickworth, David J. Rowlands, Robert H. Allen, Nicholas W. Morrell, Matthew Thomas, N Arnold, Sheila E. Francis, Sabine Guth-Gundel, Allan Lawrie, Loredana Ciuclan, Alexander M.K. Rothman
المساهمون: Morrell, Nicholas [0000-0001-5700-9792], Apollo - University of Cambridge Repository
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Hypertension, Pulmonary, Ubiquitin-Protein Ligases, Transgene, Cell, Mice, Transgenic, Pulmonary Artery, 030204 cardiovascular system & hematology, Bone morphogenetic protein, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, 0302 clinical medicine, microRNA, medicine, Animals, Humans, Rats, Wistar, Hypoxia, Aged, Gene knockdown, biology, General Medicine, Middle Aged, Hypoxia (medical), Rats, Ubiquitin ligase, Mice, Inbred C57BL, MicroRNAs, Phenotype, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Cancer research, medicine.symptom, Signal transduction, Signal Transduction
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
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المؤلفون: Margaret Nilsen, Annabel S. Campbell, Anne Katrine Johansen, Ian Morecroft, Lynn Loughlin, Kirsty M. Mair, Leigh Paton, Margaret R. MacLean, Emma Wallace, Matthew Thomas, Kevin P. White, John D. McClure, Loredana Ciuclan
المصدر: Circulation. 126:1087-1098
مصطلحات موضوعية: Male, medicine.medical_specialty, Hydroxyestrones, Hypertension, Pulmonary, CYP1B1, Myocytes, Smooth Muscle, Pulmonary Artery, Muscle hypertrophy, Mice, Right ventricular hypertrophy, Physiology (medical), medicine.artery, Internal medicine, Stilbenes, medicine, Animals, Humans, Enzyme inducer, Hypoxia, Lung, Cells, Cultured, Mice, Knockout, Estradiol, Hypertrophy, Right Ventricular, biology, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Estrogens, Hypoxia (medical), medicine.disease, Pulmonary hypertension, Cell Hypoxia, Up-Regulation, medicine.anatomical_structure, Endocrinology, Enzyme Induction, Chronic Disease, Cytochrome P-450 CYP1B1, Pulmonary artery, biology.protein, Female, Aryl Hydrocarbon Hydroxylases, medicine.symptom, Cardiology and Cardiovascular Medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b8c1830356508492781306d7e83f3e
https://doi.org/10.1161/circulationaha.111.062927 -
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المؤلفون: Jan Roger, Andrew C. Pearce, Gabor Jarai, Alan M. Holmes, David C. Budd, Loredana Ciuclan, Alexander Robinson, Victoria J. Burton
المصدر: Blood. 118:4750-4758
مصطلحات موضوعية: Leukocyte migration, Hypertension, Pulmonary, Immunology, Down-Regulation, Mice, Transgenic, Pulmonary Artery, Biology, Bone Morphogenetic Protein Receptors, Type II, Biochemistry, Receptors, Interleukin-8B, Receptors, Interleukin-8A, Proinflammatory cytokine, Mice, Vascular Biology, medicine, Animals, Humans, Bone morphogenetic protein receptor, Antihypertensive Agents, Cells, Cultured, Barrier function, Lung, Endothelial Cells, Cell Biology, Hematology, medicine.disease, Pulmonary hypertension, Extravasation, BMPR2, Chemotaxis, Leukocyte, Disease Models, Animal, medicine.anatomical_structure, Organ Specificity, Benzamides, Disease Progression, Cancer research, Cyclobutanes, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f65af2979df8b3ad3705212584f07cd
https://doi.org/10.1182/blood-2011-05-347393 -
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المؤلفون: Martin Hussey, Loredana Ciuclan, Neil John Press, Matthew Thomas
المصدر: Pharmacologytherapeutics. 138(3)
مصطلحات موضوعية: Pharmacology, Pathology, medicine.medical_specialty, Cell type, Serotonin, TPH1, business.industry, Hypertension, Pulmonary, Bioinformatics, medicine.disease, Pulmonary hypertension, BMPR2, Serotonin pathway, medicine.artery, Pulmonary artery, medicine, Animals, Humans, Pharmacology (medical), Serotonin Production, Familial Primary Pulmonary Hypertension, business
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المؤلفون: David J. Rowlands, Sarah Beach, Martin Hussey, Victoria J. Burton, Margaret R. MacLean, Peter Jones, Olivier Bonneau, Roy Fox, Irena Konstantinova, Nicholas Duggan, Robert B. Good, Andrew C. Pearce, Loredana Ciuclan, John Westwick, Matthew Thomas, Gabor Jarai, Ieuan Clay
المصدر: American journal of respiratory and critical care medicine. 187(1)
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Pathology, Serotonin, Indoles, Hypertension, Pulmonary, Pharmacology, Tryptophan Hydroxylase, Critical Care and Intensive Care Medicine, Piperazines, Receptor, Platelet-Derived Growth Factor beta, Mice, Growth factor receptor, Fibrosis, Internal medicine, medicine, Animals, Pyrroles, Phosphorylation, Hypoxia, Protein Kinase Inhibitors, Neointimal hyperplasia, Mice, Knockout, TPH1, biology, business.industry, Hemodynamics, Imatinib, Hypoxia (medical), Protein-Tyrosine Kinases, medicine.disease, Disease Models, Animal, Imatinib mesylate, Endocrinology, Pyrimidines, Benzamides, biology.protein, Imatinib Mesylate, medicine.symptom, business, Platelet-derived growth factor receptor, medicine.drug