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1دورية أكاديمية
المؤلفون: Eytan Breman, Benjamin Demoulin, Sophie Agaugué, Sebastien Mauën, Alexandre Michaux, Lorraine Springuel, Julien Houssa, Fanny Huberty, Céline Jacques-Hespel, Céline Marchand, Jérôme Marijsse, Thuy Nguyen, Nancy Ramelot, Benjamin Violle, Dorothée Daro, Peter De Waele, David E. Gilham, Valérie Steenwinckel
المصدر: Frontiers in Immunology, Vol 9 (2018)
مصطلحات موضوعية: chimeric antigen receptor, T cells, PI3K inhibitor, NKG2D, CD314, NKG2D blocking antibody, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Lorraine Springuel, Jean-Christophe Renauld, Laurent Knoops
المصدر: Haematologica, Vol 100, Iss 10 (2015)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Tekla Hornakova, Lorraine Springuel, Julien Devreux, Alexandra Dusa, Stefan N. Constantinescu, Laurent Knoops, Jean-Christophe Renauld
المصدر: Haematologica, Vol 96, Iss 6 (2011)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
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المؤلفون: Marc Van den Eynde, Alain Hendlisz, Hans Prenen, Mateusz Opyrchal, Javier Carrasco, Jean-Luc Canon, Lorraine Springuel, Frederic Lehmann, Caroline Lonez, Anne Flament, Jean-Pascal Machiels, Sylvie Rottey, David E. Gilham, Kunle Odunsi, Leila Shaza, Eric Van Cutsem, Bertrand Alexandre
المساهمون: UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - (SLuc) Unité d'oncologie médicale, UCL - (SLuc) Centre du cancer
المصدر: BIODRUGS
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 33, no. 5, p. 515-537 (2019)
Biodrugs
BioDrugs
BioDrugs, Vol. 33, no. 5, p. 515-537 (2019)مصطلحات موضوعية: EXPRESSION, Stromal cell, BLOCKADE, T-Lymphocytes, ANTITUMOR-ACTIVITY, Biotechnologie, Cell- and Tissue-Based Therapy, Review Article, Pharmacologie, LYMPHOCYTES, THERAPY, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Neoplasms, Tumor Microenvironment, medicine, Medicine and Health Sciences, Animals, Humans, DOSE-ESCALATION, Pharmacology (medical), ADOPTIVE IMMUNOTHERAPY, 030203 arthritis & rheumatology, Pharmacology, Clinical Trials as Topic, Tumor microenvironment, Receptors, Chimeric Antigen, biology, business.industry, Cancer, General Medicine, medicine.disease, CANCER, GENE, Chimeric antigen receptor, PHASE-I, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, biology.protein, Human medicine, Antibody, business, CHECKPOINT, Biotechnology
وصف الملف: Print; application/pdf; 1 full-text file(s): application/pdf
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المؤلفون: Noam Stern-Ginossar, Ofer Mandelboim, Einat Seidel, Lorraine Springuel, Julie Tai-Schmiedel, Boaz Tirosh, Eric Chevet, Miriam Shmuel, David E. Gilham, Mohamed Mahameed, Akram Obiedat, Yoav Charpak-Amikam, Tony Avril, Priya Dipta, Jennifer Bolsée
المساهمون: The Hebrew University of Jerusalem (HUJ), The Hebrew University Hadassah Medical School, Weizmann Institute of Science [Rehovot, Israël], Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes (UR)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), CRLCC Eugène Marquis (CRLCC), 0, Ministry of Science and Technology, Israel, 721236, H2020 Marie Skłodowska-Curie Actions, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Journal of Molecular Medicine (Berlin, Germany)
Journal of Molecular Medicine
Journal of Molecular Medicine, 2020, 98 (1), pp.135-148. ⟨10.1007/s00109-019-01859-w⟩
Journal of Molecular Medicine, Springer Verlag, 2020, 98 (1), pp.135-148. ⟨10.1007/s00109-019-01859-w⟩مصطلحات موضوعية: PERK, B7 Antigens, T-Lymphocytes, Eukaryotic Initiation Factor-2, [SDV.CAN]Life Sciences [q-bio]/Cancer, Blood Donors, UPR, Transfection, Immunotherapy, Adoptive, Lopinavir, 03 medical and health sciences, eIF-2 Kinase, 0302 clinical medicine, Downregulation and upregulation, Transduction, Genetic, Cell Line, Tumor, Drug Discovery, medicine, HIV Protease Inhibitor, Integrated stress response, Humans, Phosphorylation, Protein kinase A, B7H6, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Nelfinavir, Receptors, Chimeric Antigen, Kinase, Chemistry, Endoplasmic reticulum, HIV Protease Inhibitors, Endoplasmic Reticulum Stress, 3. Good health, Cell biology, CAR-T, Killer Cells, Natural, 030220 oncology & carcinogenesis, Unfolded protein response, Unfolded Protein Response, Molecular Medicine, Original Article, medicine.drug, Signal Transduction
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المؤلفون: Benjamin Violle, Céline Jacques-Hespel, Nancy Ramelot, Fanny Huberty, Eytan Breman, Peter De Waele, Sébastien Mauen, Alexandre Michaux, Lorraine Springuel, Benjamin Demoulin, Jérôme Marijsse, Thuy Nguyen, Céline Marchand, Dorothée Daro, Valérie Steenwinckel, Sophie Agaugue, David E. Gilham, Julien Houssa
المصدر: Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunologyمصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, T-Lymphocytes, Cell, Ligands, Immunotherapy, Adoptive, NKG2D, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, NKG2D blocking antibody, Immunology and Allergy, LY294002, Enzyme Inhibitors, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, Original Research, chimeric antigen receptor, biology, Chemistry, hemic and immune systems, people.cause_of_death, Cell biology, medicine.anatomical_structure, NK Cell Lectin-Like Receptor Subfamily K, Antibody, lcsh:Immunologic diseases. Allergy, Cell Survival, Morpholines, T cell, Immunology, Receptors, Antigen, T-Cell, T cells, chemical and pharmacologic phenomena, PI3K inhibitor, 03 medical and health sciences, CD314, Fratricide, Cell Line, Tumor, medicine, Humans, Antibodies, Blocking, Chimeric antigen receptor, Blockade, 030104 developmental biology, Chromones, biology.protein, K562 Cells, lcsh:RC581-607, people, fratricide
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb734f27ae0d4c1bdf4f2b10e7770dc
https://doi.org/10.3389/fimmu.2018.02940 -
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المؤلفون: David E. Gilham, Panagiota A. Sotiropoulou, Alexandre Michaux, Eytan Breman, Mikhail Steklov, Simon Bornschein, Lorraine Springuel
المصدر: Journal of Clinical Oncology. 38:3103-3103
مصطلحات موضوعية: Small hairpin RNA, Cancer Research, Gene knockdown, Oncology, business.industry, Medicine, In patient, Vector (molecular biology), Car t cells, business, Gene, Chimeric antigen receptor, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c14763a83645d16fa4c45efac9fcc9e9
https://doi.org/10.1200/jco.2020.38.15_suppl.3103 -
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المؤلفون: Béatrice Turcq, Elisabeth Losdyck, Lorraine Springuel, Pascale Saussoy, Laurent Knoops, Francois-Xavier Mahon, Jean-Christophe Renauld
المساهمون: UCL - SSS/DDUV/GECE - Génétique cellulaire, UCL - SSS/DDUV/MEXP - Médecine expérimentale, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de biologie hématologique, UCL - (SLuc) Service d'hématologie, Centre National de la Recherche Scientifique (CNRS)
المصدر: Cellular and Molecular Life Sciences, Vol. 73, no. 24, p. 4739-4748 (2016)
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2016, 73 (24), pp.4739-4748. ⟨10.1007/s00018-016-2310-2⟩مصطلحات موضوعية: 0301 basic medicine, Genome instability, MESH: Oncogenes, DNA mismatch repair, Tyrosine kinase inhibitor, medicine.disease_cause, Tyrosine-kinase inhibitor, MESH: Down-Regulation, Mice, 0302 clinical medicine, MESH: DNA Methylation, RNA interference, MESH: RNA, Small Interfering, MESH: Janus Kinases, MESH: Protein Kinase Inhibitors, MESH: Animals, RNA, Small Interfering, Promoter Regions, Genetic, Oncogenic mutations, Mutation, Gene Expression Regulation, Leukemic, MESH: MutL Protein Homolog 1, MLH1, Myeloid leukemia, MESH: Drug Resistance, Neoplasm, 3. Good health, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, MESH: Gene Expression Regulation, Leukemic, Molecular Medicine, Intercellular Signaling Peptides and Proteins, MutL Protein Homolog 1, Tyrosine kinase, medicine.drug_class, Down-Regulation, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, Cell Line, 03 medical and health sciences, Cellular and Molecular Neuroscience, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, MESH: Promoter Regions, Genetic, medicine, Animals, Humans, Point Mutation, MESH: Intercellular Signaling Peptides and Proteins, Molecular Biology, Protein Kinase Inhibitors, MESH: Mice, Janus Kinases, MESH: Point Mutation, Pharmacology, MESH: Humans, Point mutation, Janus kinase (JAK), MESH: Clone Cells, Cell Biology, Oncogenes, DNA Methylation, MESH: Gene Knockdown Techniques, Clone Cells, MESH: Cell Line, 030104 developmental biology, MESH: Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Drug Resistance, Neoplasm, Drug resistance, Cancer research, Ectopic expression
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المؤلفون: Julien Devreux, Stefan N. Constantinescu, Lorraine Springuel, Tekla Hornakova, Alexandra Dusa, Jean-Christophe Renauld, Laurent Knoops
المساهمون: UCL - SSS/DDUV - Institut de Duve, UCL - (SLuc) Service d'hématologie
المصدر: Haematologica : the hematology journal, Vol. 96, no. 6, p. 845-853 (2011)
مصطلحات موضوعية: Models, Molecular, Mutant, CHO Cells, Drug resistance, Biology, medicine.disease_cause, Binding, Competitive, Protein Structure, Secondary, Mice, Adenosine Triphosphate, Cricetulus, Cell Line, Tumor, Cricetinae, Gene Order, STAT5 Transcription Factor, medicine, Animals, Phosphorylation, Protein Kinase Inhibitors, Mutation, Janus kinase 2, Janus kinase 1, Janus Kinase 1, Original Articles, Hematology, Janus Kinase 2, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Molecular biology, Protein kinase domain, Drug Resistance, Neoplasm, Cancer research, biology.protein, Carcinogenesis, Tyrosine kinase, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a2d47471be86359d6c4f655be9c5a1
https://doi.org/10.3324/haematol.2010.036350 -
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المؤلفون: Jean-Christophe Renauld, Elisabetta Flex, Sandrine Degryse, Jan Cools, Laurent Knoops, Tekla Hornakova, Marco Tartaglia, Elisabeth Losdyck, Stefan N. Constantinescu, Olga Gielen, Lorraine Springuel
المساهمون: UCL - (SLuc) Service d'hématologie, UCL - SSS/DDUV - Institut de Duve
المصدر: Journal of Biological Chemistry, Vol. 290, no. 48, p. 29022-29034 (2015)
مصطلحات موضوعية: Mutation, Missense, Tyrosine-protein kinase (tyrosine kinase), Biology, Signal transduction, Biochemistry, Mice, hemic and lymphatic diseases, Cell Line, Tumor, CD135, Animals, Humans, Receptors, Cytokine, Receptor, Molecular Biology, Protein Kinase Inhibitors, Oncogene, Common gamma chain, Mice, Inbred BALB C, Leukemia, Janus kinase 3, Janus kinase (JAK), Janus Kinase 3, Cell Biology, Janus Kinase 1, Janus Kinase 2, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Molecular biology, Neoplasm Proteins, Amino Acid Substitution, JAK inhibitor, Interleukin-21 receptor, Cancer research, Cytokine receptor, Tyrosine kinase, Signal Transduction
وصف الملف: Print-Electronic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deb3d95fd0dfca2ff6d4dc508b94953
https://hdl.handle.net/2078.1/166226