المؤلفون: Sara Alam, Emily Doherty, Paula Ortega-Prieto, Julia Arizanova, Louise Fets

المصدر: Disease Models & Mechanisms, Vol 16, Iss 11 (2023)

مصطلحات موضوعية: cancer metabolism, drug uptake, pharmacology, transporters, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/16/11/dmm050404; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/feff507f62b14f25b04c33f86387c391

المؤلفون: Louise Fets, Natalie Bevan, Patrícia M. Nunes, Sebastien Campos, Mariana Silva dos Santos, Emma Sherriff, James I. MacRae, David House, Dimitrios Anastasiou

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/aa31f1f645774f4d82554094d5106503

المؤلفون: Lucy Penfold, Angela Woods, Alice E. Pollard, Julia Arizanova, Eneko Pascual-Navarro, Phillip J. Muckett, Marian H. Dore, Alex Montoya, Chad Whilding, Louise Fets, Joao Mokochinski, Theodora A. Constantin, Anabel Varela-Carver, Damien A. Leach, Charlotte L. Bevan, Alexander Yu. Nikitin, Zoe Hall, David Carling

المصدر: Cell Reports, Vol 42, Iss 4, Pp 112396- (2023)

مصطلحات موضوعية: CP: Cancer, CP: Metabolism, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723004072; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/11a6b824917b48fc8d5c5b5a9e0faa99

المؤلفون: Holly Newton, Yi-Fang Wang, Laura Camplese, Joao B. Mokochinski, Holger B. Kramer, André E. X. Brown, Louise Fets, Susumu Hirabayashi

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/0e28b218bcbf4e1a9a38907a77d327a9

المؤلفون: Louise Fets, Natalie Bevan, Patrícia M. Nunes, Sebastien Campos, Mariana Silva dos Santos, Emma Sherriff, James I. MacRae, David House, Dimitrios Anastasiou

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-1 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/4c039da5be434539aeae4e5f31573e64

المؤلفون: Jamie A Macpherson, Alina Theisen, Laura Masino, Louise Fets, Paul C Driscoll, Vesela Encheva, Ambrosius P Snijders, Stephen R Martin, Jens Kleinjung, Perdita E Barran, Franca Fraternali, Dimitrios Anastasiou

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: allostery, molecular dynamics, enzymology, native mass spectrometry, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/45068; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/e58bac1bbbec4b70ba28e24697d45179

المؤلفون: James I. MacRae, Ginevra Doglioni, Patrícia M. Nunes, Michalis Gounis, Cyril H. Benes, David House, Aakriti Jain, Paul C. Driscoll, Sebastien Andre Campos, Dimitrios Anastasiou, Alan J. Wright, Mariana Silva dos Santos, Nicola O’Reilly, Fiona Grimm, Kevin D. Courtney, Louise Fets, Timothy J. Ragan, George Papageorgiou

المصدر: Nature chemical biology
Nature Chemical Biology

مصطلحات موضوعية: 0301 basic medicine, Monocarboxylic Acid Transporters, Biochemical Phenomena, Glutamine, Citric Acid Cycle, Article, 03 medical and health sciences, Inhibitory Concentration 50, Mice, Adenosine Triphosphate, Cell Line, Tumor, Animals, Humans, Metabolomics, Mode of action, Molecular Biology, Monocarboxylate transporter, biology, Chemistry, Glutamate dehydrogenase, Gene Expression Profiling, Hydrolysis, Tricarboxylic Acids, Cell Biology, Metabolism, Prodrug, Cell biology, Amino Acids, Dicarboxylic, Mitochondria, Oxygen, Metabolic pathway, 030104 developmental biology, biology.protein, MCF-7 Cells, Ketoglutaric Acids, Cattle, Puromycin, Flux (metabolism), Intracellular, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975ee01bf3b610630ef535d28d0505bc
http://europepmc.org/articles/PMC6298574

المؤلفون: Louise Fets, Holger Kramer, André Ex Brown, Susumu Hirabayashi, Laura Camplese, Joao B. Mokochinski, Yi-Fang Wang, Holly Newton

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Amino Acid Transport Systems, Carcinogenesis, Dietary Sugars, PROTEIN, General Physics and Astronomy, Metabolic network, medicine.disease_cause, Animals, Genetically Modified, 0302 clinical medicine, Hemolymph, Drosophila Proteins, CANCER CACHEXIA, lcsh:Science, Wasting, chemistry.chemical_classification, INSULIN-RESISTANCE, Muscle Weakness, Multidisciplinary, Nuclear Proteins, Cancer metabolism, Amino acid, Cell biology, Multidisciplinary Sciences, DROSOPHILA, Muscular Atrophy, Drosophila melanogaster, Larva, AMINO-ACID TRANSPORTERS, Science & Technology - Other Topics, GROWTH, medicine.symptom, EXPRESSION, Proline, Science, Context (language use), Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, medicine, Animals, Amino acid transporter, Muscle, Skeletal, Science & Technology, Gene Expression Profiling, Receptor Protein-Tyrosine Kinases, YAP-Signaling Proteins, Neoplasms, Experimental, General Chemistry, Fibroblast Growth Factors, Gene expression profiling, 030104 developmental biology, chemistry, Cancer cell, Trans-Activators, ras Proteins, lcsh:Q, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eec89e6ca42aa1a5c250d9bdba4eea3
https://doi.org/10.1038/s41467-020-18502-9

المؤلفون: Louise Fets, Alina Theisen, Perdita E. Barran, Ambrosius P. Snijders, Dimitrios Anastasiou, Jens Kleinjung, Franca Fraternali, Paul C. Driscoll, Vesela Encheva, Jamie A. Macpherson, Laura Masino, Stephen R. Martin

مصطلحات موضوعية: Chemistry, Allosteric regulation, PKM2, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d3644388d550bf2fb5ddce19e60e8b8b
https://doi.org/10.7554/elife.45068.042

المؤلفون: Laura Masino, Dimitrios Anastasiou, Stephen R. Martin, Jamie A. Macpherson, Paul C. Driscoll, Ambrosius P. Snijders, Louise Fets, Alina Theisen, Vesela Encheva, Perdita E. Barran, Franca Fraternali, Jens Kleinjung

المصدر: Macpherson, J A, Theisen, A, Masino, L, Fets, L, Driscoll, P C, Encheva, V, Snijders, A P, Martin, S R, Kleinjung, J, Barran, P E, Fraternali, F & Anastasiou, D 2019, ' Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation ', eLife, vol. 8, e45068 . https://doi.org/10.7554/eLife.45068
eLife
eLife, Vol 8 (2019)
Macpherson, J A, Theisen, A, Masino, L, Fets, L, Driscoll, P C, Encheva, V, Snijders, A P, Martin, S R, Kleinjung, J, Barran, P E, Fraternali, F & Anastasiou, D 2019, ' Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation ', eLife, vol. 8 . https://doi.org/10.7554/eLife.45068

مصطلحات موضوعية: native mass spectrometry, none, Structural Biology and Molecular Biophysics, DNA Mutational Analysis, Mutant, computational biology, Fructosediphosphates, structural biology, Glycolysis, Biology (General), Enzyme Inhibitors, Chemical Biology & High Throughput, chemistry.chemical_classification, Human Biology & Physiology, 0303 health sciences, allostery, Chemistry, General Neuroscience, 030302 biochemistry & molecular biology, systems biology, General Medicine, Medicine, Intracellular, Research Article, Computational and Systems Biology, Thyroid Hormones, QH301-705.5, Science, Phenylalanine, enzymology, Immunology, Allosteric regulation, Enzyme Activators, Infectious Disease, Molecular Dynamics Simulation, PKM2, Biochemistry & Proteomics, Inhibitory postsynaptic potential, Gene Expression Regulation, Enzymologic, General Biochemistry, Genetics and Molecular Biology, Cell Line, Signalling & Oncogenes, 03 medical and health sciences, Allosteric Regulation, None, molecular biophysics, Humans, Computational & Systems Biology, 030304 developmental biology, General Immunology and Microbiology, Activator (genetics), Spectrum Analysis, FOS: Clinical medicine, Mutagenesis, Membrane Proteins, Cell Biology, Tumour Biology, molecular dynamics, Metabolism, Enzyme, Structural biology, Biophysics, Protein Multimerization, Carrier Proteins, Pyruvate kinase, Developmental Biology, Structural Biology & Biophysics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca318211df7ac2c7605a9c3bd0f014ce
https://doi.org/10.1101/378133