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1دورية أكاديمية
المؤلفون: Natalie Ives, Rebecca Woolley, Moin A Saleem, Catherine A Moakes, Aoife Waters, Rodney D Gilbert, Hugh Jarrett, Elizabeth Brettell, Steve Nash, Louise K Farmer, Khadija Ourradi, Sally A Johnson
المصدر: Efficacy and Mechanism Evaluation, Vol 11, Iss 11 (2024)
مصطلحات موضوعية: humans, child, randomised controlled trial, acute kidney injury, shiga-toxigenic escherichia coli, shiga toxin, haemolytic uraemic syndrome, complement activation, eculizumab, severity of illness index, podocytes, vascular endothelial growth factor, united kingdom (mesh), Medicine
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2050-4373
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المؤلفون: Rebecca H. Vaughan, Jean-Claude Kresse, Louise K. Farmer, Marie L. Thézénas, Benedikt M. Kessler, Jan H.N. Lindeman, Edward J. Sharples, Gavin I. Welsh, Rikke Nørregaard, Rutger J. Ploeg, Maria Kaisar
المصدر: American Journal of Transplantation, 22(4), 1073-1087. WILEY
Vaughan, R H, Kresse, J C, Farmer, L K, Thézénas, M L, Kessler, B M, Lindeman, J H N, Sharples, E J, Welsh, G I, Nørregaard, R, Ploeg, R J & Kaisar, M 2022, ' Cytoskeletal protein degradation in brain death donor kidneys associates with adverse posttransplant outcomes ', American Journal of Transplantation, vol. 22, no. 4, pp. 1073-1087 . https://doi.org/10.1111/ajt.16912
Vaughan, R, Kresse, J-C, Farmer, L K, Thézénas, M, Kessler, B, Lindeman, J, Sharples, E, Welsh, G I, Nørregaard, R, Ploeg, R & Kaisar, M 2021, ' Cytoskeletal protein degradation in brain death donor kidneys associates with adverse posttransplant outcomes ', American Journal of Transplantation . https://doi.org/10.1111/ajt.16912مصطلحات موضوعية: basic (laboratory) research/science, Brain Death, Tissue and Organ Procurement, kidney (allograft) function, translational research/science, donors and donation, injury, nephrology, basic (laboratory) research, kidney transplantation/nephrology, kidney (allograft) function/dysfunction, Kidney, proteomics, Living Donors, Immunology and Allergy, Humans, Pharmacology (medical), organ transplantation in general, donation after brain death (DBD) [donors and donation], science, donation after brain death (DBD), Transplantation, dysfunction, Graft Survival, glomerular biology and disease, QUOD biobank, Kidney Transplantation, Tissue Donors, kidney failure, Cytoskeletal Proteins, kidney failure/injury, translational research, cellular biology, Proteolysis
وصف الملف: application/pdf
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المؤلفون: David O. Bates, Monica Gamez, Andrew H.J. Salmon, Sara Desideri, Simon C. Satchell, Benjamin P. Dallyn, Siân L. Baker, Raina D. Ramnath, Peter W. Mathieson, Gavin I. Welsh, Louise K. Farmer, Nicola Buckner, Christopher R. Neal, Rebecca R. Foster, Karen L. Onions, Luigi Gnudi, Kai B. Betteridge, Kari Alitalo
المصدر: Onions, K L, Gamez, M, Buckner, N R, Baker, S L, Betteridge, K B, Desideri, S, Dallyn, B P, Ramnath, R D, Neal, C R, Farmer, L K, Mathieson, P W, Gnudi, L, Alitalo, K, Bates, D O, Salmon, A H J, Welsh, G I, Satchell, S C & Foster, R R 2019, ' VEGFC reduces glomerular albumin permeability and protects against alterations in VEGF receptor expression in diabetic nephropathy ', Diabetes, vol. 68, no. 1, pp. 172-187 . https://doi.org/10.2337/db18-0045
Onions, K, Gamez, M, Buckner, N R, Baker, S L, Betteridge, K B, Desideri, S, Dallyn, B P, Ramnath, R, Neal, C R, Farmer, L K, Mathieson, P W, Gnudi, L, Alitalo, K, Bates, D O, Salmon, A H J, Welsh, G I, Satchell, S C & Foster, R R 2019, ' VEGFC reduces glomerular albumin permeability and protects against alterations in VEGF receptor expression in diabetic nephropathy ', Diabetes, vol. 68, no. 1, pp. 172-187 . https://doi.org/10.2337/db18-0045مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Genotype, Endocrinology, Diabetes and Metabolism, Blotting, Western, Bristol Heart Institute, Fluorescent Antibody Technique, 030209 endocrinology & metabolism, urologic and male genital diseases, Diabetic nephropathy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Internal Medicine, medicine, Animals, Humans, Immunoprecipitation, Diabetic Nephropathies, Receptor, Cells, Cultured, Podocytes, urogenital system, business.industry, Vascular Endothelial Growth Factor Receptor-3, medicine.disease, female genital diseases and pregnancy complications, 3. Good health, Vascular endothelial growth factor, Vascular endothelial growth factor A, Diabetes Mellitus, Type 1, Receptors, Vascular Endothelial Growth Factor, 030104 developmental biology, Endocrinology, Vascular endothelial growth factor C, chemistry, Glomerular Filtration Barrier, Albuminuria, Microalbuminuria, medicine.symptom, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c39bf793bc204a86d876d372fe64aec
https://doi.org/10.2337/db18-0045 -
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المؤلفون: Ruth Rollason, Shang-Zhong Xu, Lutz Birnbaumer, Daniel J. Whitcomb, Lan Ni, Moin A. Saleem, Louise K. Farmer, Kate J. Heesom, Alexander Goodliff, Abigail C Lay, Gavin I. Welsh
المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Journal of the American Society of Nephrology. August 2019:ASN.2018070729
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Farmer, L, Rollason, R, Whitcomb, D, Ni, L, Goodlif, A, Lay, A, Birnbaumer, L, Heesom, K, Xu, S-Z, Saleem, M & Welsh, G 2019, ' TRPC6 Binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility ', Journal of the American Society of Nephrology, vol. 30, no. 10, pp. 1910-1924 . https://doi.org/10.1681/ASN.2018070729
J Am Soc Nephrolمصطلحات موضوعية: 0301 basic medicine, GENES, podocyte, MUTACION, Motility, glomerulus, Podocyte, Focal adhesion, purl.org/becyt/ford/1 [https], Ciencias Biológicas, Mice, 03 medical and health sciences, ENFERMEDADES RENALES, 0302 clinical medicine, Biología Celular, Microbiología, Cell Movement, parasitic diseases, Cell Adhesion, TRPC6 Cation Channel, medicine, Animals, NEFROLOGIA, Cell adhesion, Cytoskeleton, purl.org/becyt/ford/1.6 [https], Actin, Mice, Knockout, focal segmental glomerulosclerosis, biology, Calpain, Podocytes, Chemistry, PROTEINAS, RIÑON, renal cell biology, General Medicine, Actin cytoskeleton, Cell biology, Basic Research, 030104 developmental biology, medicine.anatomical_structure, Nephrology, 030220 oncology & carcinogenesis, biology.protein, TRASTORNOS GENETICOS, human activities, CIENCIAS NATURALES Y EXACTAS
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f4cad1110536e07501e256be5a0c20
https://jasn.asnjournals.org/content/30/10/1910 -
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المؤلفون: Hong, Huo, Alistair G, Fryatt, Louise K, Farmer, Ralf, Schmid, Richard J, Evans
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Models, Molecular, Binding Sites, Purinergic P2X Receptor Antagonists, antagonist, purinergic receptor, molecular docking, Rats, Receptors, Purinergic P2X1, Xenopus laevis, P2XR, Pyridoxal Phosphate, ion channel, Animals, Humans, orthosteric site, oocyte, Receptors, Purinergic P2X4, cysteine, PPADS, mutagenesis, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::2b8799a3a2bbe196c1938574138d8be5
https://pubmed.ncbi.nlm.nih.gov/29997254 -
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المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Agonist, Time Factors, Purinergic P2X Receptor Antagonists, medicine.drug_class, Intracellular Space, Biology, Models, Biological, Biochemistry, Partial agonist, Protein Structure, Secondary, Ion Channels, Purinergic P2X Receptor Agonists, Structure-Activity Relationship, Xenopus laevis, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, 0302 clinical medicine, medicine, Extracellular, Animals, Humans, PPADS, Receptor, Molecular Biology, 030304 developmental biology, Pharmacology, 0303 health sciences, fungi, Cell Biology, Recombinant Proteins, Protein Structure, Tertiary, 3. Good health, Cell biology, Receptors, Purinergic P2X1, ATP, Electrophysiology, Transmembrane domain, chemistry, Mutagenesis, Pyridoxal Phosphate, Extracellular Space, Ion Channel Gating, 030217 neurology & neurosurgery, Receptors, Purinergic P2X2, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfccf3b26fa6cc324f83fead0f0f0748
https://doi.org/10.1074/jbc.m113.464651 -
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المؤلفون: Steven J. Ennion, Volko A. Straub, Louise K. Farmer, Shire K Singh, Felix D Guerrero, Selvan Bavan
المصدر: Molecular Pharmacology. 79:776-785
مصطلحات موضوعية: Time Factors, Arginine, medicine.medical_treatment, Suramin, Molecular Sequence Data, Mutant, Biology, Xenopus laevis, Ticks, Homologous desensitization, medicine, Animals, Amino Acid Sequence, Receptor, Ion channel, Desensitization (medicine), Pharmacology, C-terminus, Articles, Molecular biology, Peptide Fragments, Protein Structure, Tertiary, Receptors, Purinergic P2X, Mutation, Biophysics, Molecular Medicine, Cattle, Female, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8602b768aed9753984a0ced07344e0a
https://doi.org/10.1124/mol.110.070037 -
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المؤلفون: Louise K, Farmer, Ralf, Schmid, Richard J, Evans
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Models, Molecular, NF449, Purinergic P2X Receptor Antagonists, Suramin, Molecular Dynamics Simulation, Ligands, Ligand-gated Ion Channel, Mice, Xenopus laevis, Adenosine Triphosphate, Ion Channel, Animals, Humans, Point Mutation, Cysteine, PPADS, Binding Sites, Lysine, Benzenesulfonates, Rats, ATP, Electrophysiology, Mutagenesis, Drug Design, Mutagenesis, Site-Directed, Oocytes, Purinergic Receptor, P2X Receptor, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::845a78b502ee376258941786d2836bba
https://pubmed.ncbi.nlm.nih.gov/25425641