يعرض 1 - 10 نتائج من 61 نتيجة بحث عن '"Louise Tee"', وقت الاستعلام: 0.85s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Complete response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT mutations and high tumour mutational burden

    المؤلفون: Joanne D. Stockton, Louise Tee, Celina Whalley, Jonathan James, Mark Dilworth, Rachel Wheat, Thomas Nieto, S-CORT Consortium, Ian Geh, João D. Barros-Silva, Andrew D. Beggs

    المصدر: Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)

    مصطلحات موضوعية: Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1748-717X

    URL الوصول: https://doaj.org/article/e778f28ee9ec4faebfafc381306dd3be

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest Full Text Finder
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  2. 2
    دورية أكاديمية
    Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer

    المؤلفون: Kasun Wanigasooriya, Joao D. Barros-Silva, Louise Tee, Mohammed E. El-asrag, Agata Stodolna, Oliver J. Pickles, Joanne Stockton, Claire Bryer, Rachel Hoare, Celina M. Whalley, Robert Tyler, Toritseju Sillo, Christopher Yau, Tariq Ismail, Andrew D. Beggs

    المصدر: Frontiers in Oncology, Vol 12 (2022)

    مصطلحات موضوعية: colorectal cancer, organoid, radiotherapy, PI3K - AKT pathway, mTOR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.920444/full; https://doaj.org/toc/2234-943X

    URL الوصول: https://doaj.org/article/a68422d51da247698891b279834c4704

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  3. 3
    Abstract 2989: Colorectal cancer displays three patterns of tumor-specific MHC-II inducibility and dynamics, with implications for combining epigenetic therapy with immunotherapy

    المؤلفون: Oliver J. Pickles, Kasun Wanigasooriya, Anetta Ptasinska, Akshay J. Patel, Helen L. Robbins, Claire Bryer, Celina M. Whalley, Louise Tee, Neeraj Lal, Maria Pinna, Nahla Elzefzafy, Phillipe Taniere, Andrew D. Beggs, Gary W. Middleton

    المصدر: Cancer Research. 83:2989-2989

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e3accfb5e078a2cd2bb682573f50c053
    https://doi.org/10.1158/1538-7445.am2023-2989

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  4. 4
    Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer

    المؤلفون: Oliver J Pickles, Andrew D Beggs, Gary Middleton, Louise Tee, Aneta Drozd

    المصدر: Oncotarget

    مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, medicine.medical_treatment, Context (language use), colorectal cancer, encorafenib, Targeted therapy, BRAF, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Encorafenib, medicine, Vemurafenib, neoplasms, paradox breaker, Cetuximab, business.industry, Melanoma, Binimetinib, medicine.disease, digestive system diseases, PLX8394, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, business, medicine.drug, Research Paper

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46857e202d1849bfbdaf09f7f3bf121
    http://europepmc.org/articles/PMC7456617

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  5. 5
    Patient derived organoids reveal that PI3K/AKT signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer

    المؤلفون: Celina Whalley, Andrew D Beggs, Oliver J Pickles, Rachel Hoare, Kasun Wanigasooriya, Tortieju Sillo, Mohammed E. El-Asrag, Robert Tyler, Louise Tee, Tariq Ismail, João D. Barros-Silva, Agata Stodolna, Joanne D. Stockton, Christopher Yau, Claire Bryer

    مصطلحات موضوعية: Biological pathway, Downregulation and upregulation, business.industry, Colorectal cancer, Radioresistance, Cancer cell, Cancer research, Medicine, mTORC1, business, medicine.disease, Protein kinase B, PI3K/AKT/mTOR pathway

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::30f360ef6663cfb090a839265b85f193
    https://doi.org/10.1101/2021.08.31.458326

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  6. 6
    Complete response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT mutations and high tumour mutational burden

    المؤلفون: Rachel Wheat, João D. Barros-Silva, Andrew D Beggs, Celina Whalley, Mark P Dilworth, Jonathan James, Thomas Nieto, Ian Geh, Joanne D. Stockton, Louise Tee

    المصدر: Radiation Oncology (London, England)
    Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)

    مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Tumour heterogeneity, Colorectal cancer, medicine.medical_treatment, DNA Mutational Analysis, R895-920, Adenocarcinoma, Clonal Evolution, Cohort Studies, 03 medical and health sciences, Medical physics. Medical radiology. Nuclear medicine, 0302 clinical medicine, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Protein kinase B, Exome sequencing, PI3K/AKT/mTOR pathway, RC254-282, Germ-Line Mutation, Retrospective Studies, business.industry, Rectal Neoplasms, Research, Remission Induction, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Chemoradiotherapy, medicine.disease, Neoadjuvant Therapy, Radiation therapy, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Genes, ras, Treatment Outcome, 030220 oncology & carcinogenesis, Case-Control Studies, Immunohistochemistry, Female, business, Proto-Oncogene Proteins c-akt

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1970bf74cfdac3cd53dee6b4e183a4fd
    https://pubmed.ncbi.nlm.nih.gov/34256782

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
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  7. 7
    Childhood obesity

    المؤلفون: Julie Lanigan, Louise Tee, Rachael Brandreth

    المصدر: Medicine. 47:190-194

    مصطلحات موضوعية: General Medicine

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::24038611cbb2e5f2c634183022c85680
    https://doi.org/10.1016/j.mpmed.2018.12.007

    View record from ScienceDirect Full Text via ClinicalKey
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  8. 8
    Evidence that autosomal recessive spastic cerebral palsy-1 (CPSQ1) is caused by a missense variant in HPDL

    المؤلفون: Diana Walsh, Graeme R. Clark, Ezequiel Martin, Neil V. Morgan, Louise Tee, Hannah Titheradge, Evan Reid, Mary O'Driscoll, Eamonn R. Maher, Bryndis Yngvadottir

    المساهمون: Martin, Ezequiel [0000-0002-0051-8868], Reid, Evan [0000-0003-1623-7304], Maher, Eamonn R [0000-0002-6226-6918], Apollo - University of Cambridge Repository

    المصدر: Brain Communications

    مصطلحات موضوعية: 0301 basic medicine, Genetics, cerebral palsy, business.industry, General Engineering, autosomal recessive, medicine.disease, inherited, Cerebral palsy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Spastic cerebral palsy, Genetic linkage, Paralysis, Spastic, Missense mutation, Medicine, Original Article, medicine.symptom, business, 030217 neurology & neurosurgery, Loss function, Exome sequencing

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963925c09b25fd4fb0d71debf31d4f84

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  9. 9
    Response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT pathway dysregulation and high tumour mutational burden

    المؤلفون: Rachel Wheat, Andrew D Beggs, Mark P Dilworth, Jonathan James, Joanne D. Stockton, Louise Tee, Ian Geh, Celina Whalley, Thomas Nieto

    مصطلحات موضوعية: Tumour heterogeneity, medicine.diagnostic_test, Colorectal cancer, business.industry, DNA Repair Pathway, medicine.disease, Biopsy, medicine, Cancer research, business, Protein kinase B, PI3K/AKT/mTOR pathway, Exome sequencing, Chemoradiotherapy

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::092de73419f62a59d0b4b69d16d12523
    https://doi.org/10.1101/2020.02.01.20019794

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  10. 10
    Health and population effects of rare gene knockouts in adult humans with related parents

    المؤلفون: Kenneth Paigen, John Wright, Rosie McEachan, Eamonn Sheridan, Dan Mason, Yali Xue, Laura Southgate, Richard C. Trembath, Konrad J. Karczewski, Anne H. O’Donnell-Luria, Monkol Lek, Kristina Giorda, David A. van Heel, Srikanth Bellary, Chris Tyler-Smith, Mark G. Thomas, Louise Tee, Vagheesh M. Narasimhan, Michael Schnall-Levin, Shane A. McCarthy, Eamonn R. Maher, Jia Zhilong, Hajrah A. Khawaja, Harry Hemingway, Christopher M. Bates, Christopher L. Baker, Ann M. Kelly, Petko M. Petkov, Daniel G. MacArthur, Nicholas A. Bockett, Constantinos A. Parisinos, Anthony H. Barnett, Karen A. Hunt, Richard Durbin, Chris Griffiths, Michael R. Barnes

    المصدر: Science. 352:474-477

    مصطلحات موضوعية: 0301 basic medicine, Genetics, education.field_of_study, Multidisciplinary, Population, Biology, Genome, 3. Good health, 03 medical and health sciences, 030104 developmental biology, Gene Knockout Techniques, education, Gene, Exome, Gene knockout, PRDM9, Exome sequencing

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::329edb47570eee0a17f6ad1922551549
    https://doi.org/10.1126/science.aac8624

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