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المؤلفون: Loutet SA; NovoBind Livestock Therapeutics, Vancouver, British Columbia V6E 0C3, Canada., Cheung S; NovoBind Livestock Therapeutics, Vancouver, British Columbia V6E 0C3, Canada., Zaytsoff S; NovoBind Livestock Therapeutics, Vancouver, British Columbia V6E 0C3, Canada., Hofacre C; Southern Poultry Research Group, Inc., Watkinsville, GA 30677, USA., Jones MK; Southern Poultry Research Group, Inc., Watkinsville, GA 30677, USA., Van Petegem F; Department of Biochemistry and Molecular Biology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Abnousi H; NovoBind Livestock Therapeutics, Vancouver, British Columbia V6E 0C3, Canada. Electronic address: info@novobind.com.

المصدر: Poultry science [Poult Sci] 2024 Apr; Vol. 103 (4), pp. 103578. Date of Electronic Publication: 2024 Feb 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

مواضيع طبية MeSH: Single-Domain Antibodies* , Clostridium Infections*/prevention & control , Clostridium Infections*/veterinary , Enteritis*/prevention & control , Enteritis*/veterinary , Poultry Diseases*/prevention & control , Poultry Diseases*/microbiology, Animals ; Clostridium perfringens/genetics ; Poultry ; Incidence ; Chickens

المؤلفون: Verstraete MM; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Morales LD; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Kobylarz MJ; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Loutet SA; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Laakso HA; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada., Pinter TB; Department of Chemistry, University of Western Ontario, London, Ontario N6A 5C1, Canada., Stillman MJ; Department of Chemistry, University of Western Ontario, London, Ontario N6A 5C1, Canada., Heinrichs DE; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada., Murphy MEP; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada michael.murphy@ubc.ca.

المصدر: The Journal of biological chemistry [J Biol Chem] 2019 Jul 26; Vol. 294 (30), pp. 11622-11636. Date of Electronic Publication: 2019 Jun 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*physiology , Citrates/*biosynthesis , Heme/*metabolism , Staphylococcus aureus/*metabolism, Adenosine Diphosphate/metabolism ; Bacterial Proteins/biosynthesis ; Bacterial Proteins/genetics ; Catalysis ; Citrates/metabolism ; Genes, Bacterial ; Protein Binding ; Protein Conformation ; Staphylococcus aureus/genetics

المؤلفون: Kobylarz MJ; The Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia , Vancouver, British Columbia V6T 1Z3; Canada., Heieis GA; The Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia , Vancouver, British Columbia V6T 1Z3; Canada., Loutet SA; The Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia , Vancouver, British Columbia V6T 1Z3; Canada., Murphy MEP; The Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia , Vancouver, British Columbia V6T 1Z3; Canada.

المصدر: ACS chemical biology [ACS Chem Biol] 2017 Jul 21; Vol. 12 (7), pp. 1778-1786. Date of Electronic Publication: 2017 May 12.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Benzoquinones/*chemistry , Flavin-Adenine Dinucleotide/*chemistry , Iron/*metabolism , Oxidoreductases/*metabolism , Siderophores/*metabolism, Anaerobiosis ; Binding Sites ; Cloning, Molecular ; Crystallography, X-Ray ; Kinetics ; Models, Molecular ; NADP/chemistry ; Oxidation-Reduction ; Oxidoreductases/chemistry

المؤلفون: El-Halfawy OM; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.; Microbiology and Immunology Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Klett J; Department of Chemical and Physical Biology, Centre for Biological Research, CIB, CSIC, Madrid, Spain., Ingram RJ; The Wellcome-Wolfson Institute of Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom., Loutet SA; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada., Murphy ME; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada., Martín-Santamaría S; Department of Chemical and Physical Biology, Centre for Biological Research, CIB, CSIC, Madrid, Spain., Valvano MA; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada m.valvano@qub.ac.uk.; The Wellcome-Wolfson Institute of Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.

المصدر: MBio [mBio] 2017 Mar 14; Vol. 8 (2). Date of Electronic Publication: 2017 Mar 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Bacterial*, Anti-Bacterial Agents/*metabolism , Burkholderia cenocepacia/*drug effects , Burkholderia cenocepacia/*metabolism , Lipocalins/*metabolism, Gene Expression ; Methicillin-Resistant Staphylococcus aureus/genetics ; Mycobacterium tuberculosis/genetics ; Pseudomonas aeruginosa/genetics

المؤلفون: Loutet SA; Centre for Human Immunology, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., El-Halfawy OM; Centre for Human Immunology, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Jassem AN; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., López JM; Biomar Microbial Technologies, León, Spain., Medarde AF; Biomar Microbial Technologies, León, Spain., Speert DP; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada; Department of Pathology, University of British Columbia, Vancouver, BC, Canada., Davies JE; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Valvano MA; Centre for Human Immunology, Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada; Centre for Infection and Immunity, Queen's University Belfast, Belfast, UK. Electronic address: m.valvano@qub.ac.uk.

المصدر: International journal of antimicrobial agents [Int J Antimicrob Agents] 2015 Oct; Vol. 46 (4), pp. 376-80. Date of Electronic Publication: 2015 Jun 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

مواضيع طبية MeSH: Drug Synergism*, Anti-Bacterial Agents/*pharmacology , Biological Products/*pharmacology , Burkholderia cepacia complex/*drug effects , Polymyxin B/*pharmacology, Biological Products/isolation & purification ; Humans

المؤلفون: Takayama SJ; †Department of Microbiology and Immunology, ‡Department of Biochemistry and Molecular Biology, and §UBC Centre for Blood Research, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Loutet SA; †Department of Microbiology and Immunology, ‡Department of Biochemistry and Molecular Biology, and §UBC Centre for Blood Research, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Mauk AG; †Department of Microbiology and Immunology, ‡Department of Biochemistry and Molecular Biology, and §UBC Centre for Blood Research, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Murphy ME; †Department of Microbiology and Immunology, ‡Department of Biochemistry and Molecular Biology, and §UBC Centre for Blood Research, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.

المصدر: Biochemistry [Biochemistry] 2015 Apr 28; Vol. 54 (16), pp. 2613-21. Date of Electronic Publication: 2015 Apr 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*chemistry , Heme/*chemistry , Heme Oxygenase (Decyclizing)/*chemistry , Iron/*chemistry , Staphylococcus aureus/*enzymology, Bacterial Proteins/metabolism ; Binding Sites ; Heme/metabolism ; Heme Oxygenase (Decyclizing)/metabolism ; Hydrogen Peroxide/chemistry ; Hydrophobic and Hydrophilic Interactions ; Iron/metabolism ; Oxidation-Reduction

المؤلفون: Loutet SA, Chan ACK, Kobylarz MJ, Verstraete MM, Pfaffen S, Ye B, Arrieta AL, Murphy MEP

المصدر: 2015.

المصدر: In: Trace Metals and Infectious Diseases Nriagu JO; Skaar EP
Chapter 4
9780262029193

نوع المنشور: Review

بيانات الدورية: Publisher: MIT Press Cited Medium: Internet

المؤلفون: Loutet SA; From the Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Kobylarz MJ; From the Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Chau CHT; From the Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada., Murphy MEP; From the Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. Electronic address: michael.murphy@ubc.ca.

المصدر: The Journal of biological chemistry [J Biol Chem] 2013 Sep 06; Vol. 288 (36), pp. 25749-25759. Date of Electronic Publication: 2013 Jul 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*metabolism , Flavoproteins/*metabolism , Heme/*metabolism , Iron/*metabolism , Mixed Function Oxygenases/*metabolism , Oxygenases/*metabolism , Staphylococcus aureus/*enzymology, Bacterial Proteins/genetics ; Flavoproteins/genetics ; Heme/genetics ; Hydrogen Peroxide/pharmacology ; Mixed Function Oxygenases/genetics ; NADP/genetics ; NADP/metabolism ; Oxidants/pharmacology ; Oxygenases/genetics ; Staphylococcus aureus/genetics

المؤلفون: Lee TW; Department of Biochemistry and Biomedical Sciences and Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada., Verhey TB, Antiperovitch PA, Atamanyuk D, Desroy N, Oliveira C, Denis A, Gerusz V, Drocourt E, Loutet SA, Hamad MA, Stanetty C, Andres SN, Sugiman-Marangos S, Kosma P, Valvano MA, Moreau F, Junop MS

المصدر: Journal of medicinal chemistry [J Med Chem] 2013 Feb 28; Vol. 56 (4), pp. 1405-17. Date of Electronic Publication: 2013 Jan 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*chemistry , Bacterial Proteins/*chemistry , Burkholderia cenocepacia/*enzymology , Phosphotransferases (Alcohol Group Acceptor)/*chemistry, Bacterial Proteins/genetics ; Burkholderia cenocepacia/genetics ; Crystallography, X-Ray ; Models, Molecular ; Mutation ; Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors ; Phosphotransferases (Alcohol Group Acceptor)/genetics ; Protein Conformation ; Structure-Activity Relationship ; Virulence